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| Product | Description | |
|---|---|---|
| L67 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| L67 | L67 (DNA Ligase Inhibitor) is a competitive DNA ligase inhibitor that effectively inhibits DNA ligases I/III (both IC 50 are 10 μM). L67 can cause nuclear DNA damage by reducing levels of mitochondrial DNA and increasing levels of mitochondrially-generated ROS. L67 also activates the Caspase 1 -dependent apoptosis pathway in cancer cells, can be used in cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DNA Ligase Inhibitor. CAS No. 325970-71-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15586. |  |
| L67 | L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple competitive inhibitor with respect to nicked DNA. L67 inhibits DNA ligases I and III with IC50 values of 10 μM and 10 μM.). Synonyms: L67; L-67; L 67. Grades: 98%. CAS No. 325970-71-6. Molecular formula: C16H14Br2N4O4. Mole weight: 486.12. |  |
| Anti-COVID-19 Traditional Chinese Medicine Compound Library | A unique collection of 1162 monomers from 70 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening?- Sources are 70 TCM plants including Lonicera japonica Thunb. , Forsythia suspensa, Scutellaria baicalensis Georgi, Bupleuri Radix, Agastache rugosa, Isatidis Radix, Rhodiola rosea, etc. ?- Structurally diverse: including Flavonoids, alkaloids, Polyphenols, Terpenes, ets. ; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6720. Categories: Anti-COVID-19 Traditional Chinese Medicine Compounds Libraries. |  |
| Anti-Inflammatory Traditional Chinese Medicine Compound Library | A collection of 1040 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study?- Covers various targets such as COX, CCR, STAT, TGFβ, etc. involved in inflammation?- Diversity: includes Flavone, Saponins, Terpenes, Alkaloids, etc. ?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L6710. Categories: Anti-Inflammatory Traditional Chinese Medicine Compounds Libraries. | |
| Anti-Tumor Natural Product Library | A unique collection of 1471 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); - Known bioactivity for all compounds: detailed biological and pharmacological information, providing the research foundation and theoretical direction for screening; - Clear source: known active natural products selected from animals, plants, or microorganisms with clear species information; - Detailed compound information with structure, solubility, targeted signal pathways, action sites, and biological activity description; - Cost-effectiveness: expensive natural products with poor drug likeliness are excluded, allowing for more high-quality natural products at a lower cost. Uses: Scientific use. Product Category: L6700. Categories: Anti-Tumor Natural Product Libraries. | |
| Anti-virus Traditional Chinese Medicine Monomer Library | A collection of 270 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies. Uses: Scientific use. Product Category: L6730. Categories: Anti-virus Traditional Chinese Medicine Monomer Libraries. | |
| Dorzolamide hydrochloride | Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC 50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: L671152 hydrochloride; MK507 hydrochloride. CAS No. 130693-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 250 mg. Product ID: HY-B0109A. | |
| Dorzolamide Impurity A | Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Uses: Carbonic anhydrase inhibitors. Synonyms: L671152; MK507; L 671152; MK 507; L-671152; MK-507; Trusopt. Grades: >98%. CAS No. 120279-96-1. Molecular formula: C10H16N2O4S3. Mole weight: 324.44. | |
| L-670,596 | L-670,596 is a potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist with IC50 value of 5.5 nM. It displays ALDH1A1 specific inhibitory activity. It inhibits human platelet aggregation and U-44069-induced contractions of guinea pig trachea in vitro. It also inhibits thromboxane-mediated endothelial cell death. It is orally active in vivo. Synonyms: L-670596; L 670596; L670596; (-)-6-8-Difluoro-2,3,4,9-tetrahydro-9-[[4-(methylsulfonyl)phenyl]methyl]-1H-carbazole-1-acetic acid; 2-[6,8-Difluoro-9-[(4-methylsulfonylphenyl)methyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid. Grades: ≥98% by HPLC. CAS No. 121083-05-4. Molecular formula: C22H21F2NO4S. Mole weight: 433.47. | |
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