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The enzyme is found in the bacterium Rhodopseudomonas palustris, which produces N-(4-coumaroyl)-L-homoserine lactone as a quorum-sensing signal. Group: Enzymes. Synonyms: p-coumaryl-homoserine lactone synthase; RpaI. Enzyme Commission Number: EC 2.3.1.229. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2176; 4-coumaroyl-homoserine lactone synthase; EC 2.3.1.229; p-coumaryl-homoserine lactone synthase; RpaI. Cat No: EXWM-2176.
acyl-homoserine-lactone synthase
Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing. Each bacterial cell has a basal level of AHL and, once the population density reaches a critical level, it triggers AHL-signalling which, in turn, initiates the expression of particular virulence genes. N-(3-Oxohexanoyl)-[acyl-carrier protein] and hexanoyl-[acyl-carrier protein] are the best substrates. The fatty-acyl substrate is derived from fatty-acid biosynthesis through acyl-[acyl-carrier protein] rather than from fatty-acid degradation through acyl-CoA. S-Adenosyl-L-methionine cannot be rep...No. 176023-66-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2126; acyl-homoserine-lactone synthase; EC 2.3.1.184; 176023-66-8; acyl-homoserine lactone synthase; acyl homoserine lactone synthase; acyl-homoserinelactone synthase; acylhomoserine lactone synthase; AHL synthase; AHS; AHSL synthase; AhyI; AinS; AinS protein; autoinducer synthase; autoinducer synthesis protein rhlI; EsaI; ExpISCC1; ExpISCC3065; LasI; LasR; LuxI; LuxI protein; LuxM; N-acyl homoserine lactone synthase; RhlI; YspI acyl-[acyl carrier protein]:S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadeno
isovaleryl-homoserine lactone synthase
The enzyme, found in the bacterium Bradyrhizobium japonicum, does not accept isovaleryl-[acyl-carrier protein] as acyl donor (cf. EC 2.3.1.184, acyl-homoserine-lactone synthase). Group: Enzymes. Synonyms: IV-HSL synthase; BjaI. Enzyme Commission Number: EC 2.3.1.228. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2175; isovaleryl-homoserine lactone synthase; EC 2.3.1.228; IV-HSL synthase; BjaI. Cat No: EXWM-2175.
6-deoxyerythronolide-B synthase
The product, 6-deoxyerythronolide B, contains a 14-membered lactone ring and is an intermediate in the biosynthesis of erythromycin antibiotics. Biosynthesis of 6-deoxyerythronolide B requires 28 active sites that are precisely arranged along three large polypeptides, denoted DEBS1, -2 and -3. The polyketide product is synthesized by the processive action of a loading didomain, six extension modules and a terminal thioesterase domain. Each extension module contains a minimum of a ketosynthase (KS), an acyltransferase (AT) and an acyl-carrier protein (ACP).The KS domain both accepts the growing polyketide chain from the previous module and catalyses the subsequent decarboxylat...e (cyclizing); erythronolide synthase; malonyl-CoA:propanoyl-CoA malonyltransferase (cyclizing); deoxyerythronolide B synthase; 6-deoxyerythronolide B synthase; DEBS. Enzyme Commission Number: EC 2.3.1.94. CAS No. 87683-77-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2276; 6-deoxyerythronolide-B synthase; EC 2.3.1.94; 87683-77-0; erythronolide condensing enzyme; malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing); erythronolide synthase; malonyl-CoA:propanoyl-CoA malonyltransferase (cyclizing); deoxyerythronolide B synthase; 6-deoxyerythronolide B synthase; DEBS. Cat No: EXWM-2276.
Antibiotic 1233B
It is a β-lactone antibiotic produced by the strain of Cephalosporium sp. It has a strong inhibitory effect on hydroxymethyl glutaryl coenzyme A (HMG-CoA) synthase. Synonyms: 1233B; 3,5,7-trimethyl-12-hydroxy-13-hydroxymethyl-2,4-tetradecadiendioic acid; 2,4-Tetradecadienedioic acid, 12-hydroxy-13-(hydroxymethyl)-3,5,7-trimethyl-. CAS No. 34668-58-1. Molecular formula: C18H30O6. Mole weight: 342.43.
costunolide synthase
A heme-thiolate protein (P-450). The enzyme hydroxylates carbon C-6 of germacra-1(10),4,11(13)-trien-12-oate to give 6α-hydroxygermacra-1(10),4,11(13)-trien-12-oate, which probably spontaneously cyclises to form the lactone ring. Group: Enzymes. Enzyme Commission Number: EC 1.14.13.120. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0721; costunolide synthase; EC 1.14.13.120. Cat No: EXWM-0721.
Hymeglusin
It is a β-lactone antibiotic produced by the strain of Cephalosporium sp. It has a strong inhibitory effect on hydroxymethyl glutaryl coenzyme A (HMG-CoA) synthase. Synonyms: Antibiotic 1233A; 1233A; Antibiotic F 244; (R,R)-Hymeglusin; 2,4-Undecadienoic acid, 11-(3-(hydroxymethyl)-4-oxo-2-oxetanyl)-3,5,7-trimethyl-, (2R-(2-alpha(2E,4E,7R*),3-beta))-; Antibiotic L 659699. Grades: ≥95%. CAS No. 29066-42-0. Molecular formula: C18H28O5. Mole weight: 324.41.
L-Homoserine lactone
L-Homoserine lactone (HSL), comprises a homoserine lactone ring and a fatty acyl side. The levels of L-Homoserine lactone in bacteria is dictated by the availability of the substrates and acyl-homoserine lactones synthase. Synonyms: (S)-3-aminodihydrofuran-2(3H)-one. CAS No. 2185-2-6. Molecular formula: C4H7NO2. Mole weight: 101.10.
N-(β-Ketocaproyl)-L-homoserine lactone
N-(β-Ketocaproyl)-L-homoserine lactone (3-oxo-C6-HSL) is one of the quorum signaling molecules for V. fischeri. 3-oxo-C6-HSL is produced by LuxI autoinducer synthase catalyzed reaction between S-adenosylmethionine and acylated-acyl carrier proteins (Acyl-ACPs). It can be used in analyzing the expression of the orthogonal specialized reporter genes. Uses: Detection peptide synthesis. Additional or Alternative Names: N-(3-Oxohexanoyl)-L-homoserine lactone. Product Category: Amino Acids. CAS No. 143537-62-6. Mole weight: 213.23. Canonical SMILES: CCCC(=O)CC(=O)N[C@H]1CCOC1=O. Product ID: ACM143537626-1. Alfa Chemistry ISO 9001:2015 Certified.
(R,R)-Hymeglusin
beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. Group: Biochemicals. Alternative Names: 1233A, F-244, L-659-699. Grades: Highly Purified. CAS No. 29066-42-0. Pack Sizes: 500ug, 1mg, 2.5mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
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