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| Product | Description | |
|---|---|---|
| Lapatinib ditosylate | Lapatinib ditosylate. CAS No. 388082-78-8. Product ID: 2-08244. Molecular formula: C29H26ClFN4O4S.2(C7H8O3S). Mole weight: 925.46. |  |
| Lapatinib ditosylate | Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW572016 ditosylate; GW2016 ditosylate. CAS No. 388082-77-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50898A. |  |
| Lapatinib Ditosylate | Lapatinib Ditosylate. CAS No. 388082-78-8. Product ID: 8-04224. Molecular formula: C29H26ClFN4O4S.2(C7H8O3S). Mole weight: 925.46. | |
| Lapatinib Ditosylate | Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Uses: Antineoplastic agents. Synonyms: GW-572016; GW 572016; GW572016. Grades: >98%. CAS No. 388082-77-7. Molecular formula: C29H26ClFN4O4S.2C7H8O3S. Mole weight: 925.46. |  |
| Lapatinib Ditosylate | Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine Bis (4-methyl Benzene sulfonate) Ditosylate; GW-572016F Ditosylate; Tykerb Ditosylate. Grades: Highly Purified. CAS No. 388082-77-7. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Lapatinib ditosylate monohydrate | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C29H26ClFN4O4S ·2(C7H8O3S) ·H2O. CAS No. 388082-78-8. Prepack ID 13289809-100mg. Molecular Weight 943.48. See USA prepack pricing. |  |
| Lapatinib ditosylate monohydrate | Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW572016 ditosylate monohydrate; GW2016 ditosylate monohydrate. CAS No. 388082-78-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-50898B. | |
| Lapatinib-13C2,15N Ditosylate | Labeled Lapatinib. Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine Bis (4-methyl Benzene sulfonate) -13C2, 15N Ditosylate; GW-572016F-13C2,15N; Tykerb-13C2,15N Ditosylate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Lapatinib Impurity 1 (O-De(3-fluorobenzyl) Lapatinib) Ditosylate Salt | Synonyms: 2-Chloro-4-[[6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinyl]amino]phenol Ditosylate Salt. Grades: > 95%. Molecular formula: C36H37ClN4O10S3. Mole weight: 817.35. | |
| O-De(3-fluorobenzyl) Lapatinib Ditosylate Salt | A reactive metabolite of Lapatinib which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites. Group: Biochemicals. Alternative Names: 2-Chloro-4- [ [6- [5- [ [ [2- (methylsulfonyl) ethyl] amino] methyl] -2-furanyl] -4-quinazolinyl] amino] phenol Ditosylate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Lapatinib, Free Base | ATP-competitive EGFR & ErbB-2 dual tyrosine kinase inhibitor. Lapatinib is an ATP-competitive epidermal growth factor receptor (EGFR) and HER2/neu (ErbB-2) dual tyrosine kinase inhibitor, with IC(50) values of 10.8 and 9.2nm respectively. It is an orally active drug for treatment of breast cancer and other solid tumors. A free base form of Lapatinib Ditosylate. Lapatinib (as the di-p-toluenesulfonate salt) is the active ingredient in the drug sold under the trade names Tykerb in the US and Tyverb in Europe. This drug has been approved in at least one country to treat advanced metastatic breast cancer in conjunction with the chemotherapy drug Xeloda (generic name, capecitabine). Group: Biochemicals. Alternative Names: N-[3-Chloro-4-[ (3-fluorophenyl) methoxy]phenyl]-6-[5-[[[2- (methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine, GSK 572016, GW-572016, GW 572016X, Tykerb, Tyverb. Grades: Highly Purified. CAS No. 231277-92-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
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