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| Product | Description | |
|---|---|---|
| Ledipasvir | Ledipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection. Uses: Antiviral agents. Synonyms: GS5885; GS-5885; GS 5885; Ledipasvir; trade name: Harvoni. Grades: >98%. CAS No. 1256388-51-8. Molecular formula: C49H54F2N8O6. Mole weight: 889.0. |  |
| Ledipasvir | Ledipasvir (GS-5885) is an inhibitor of the hepatitis C virus NS5A , with EC 50 s of 34 pM and 4 pM against genotype 1a and 1b replicon, respectively. Ledipasvir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.62 μM [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5885. CAS No. 1256388-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15602. |  |
| Ledipasvir acetone | Ledipasvir is an inhibitor of hepatitis C virus NS5A. Synonyms: GS 5885 acetone; GS5885 acetone; GS-5885 acetone; methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate compound with propan-2-one (1:1). Grades: >98%. CAS No. 1441674-54-9. Molecular formula: C52H60F2N8O7. Mole weight: 947.08. | |
| Ledipasvir diacetone | Against JFH1/3a-NS5A, DCV was more potent (EC(50) = 0.52 nM) than GS-5885 (EC(50) = 141 nM). DCV sensitivity was increased against JFH1/3a-NS5A-M28V (EC50 = 0.006 nM), A30V (EC(50) = 0.012 nM), and E92A (EC(50) = 0.004 nM) while the NS5A-A30K and -Y93H variants exhibited reduced sensitivity to DCV (EC50 values of 23 nM and 1120 nM, respectively) and to GS-5885 (EC50 values of 1770 nM and 4300 nM, respectively). GS-5885 was well tolerated and resulted in median maximal reductions in HCV RNA ranging from 2.3 log(10) IU/ml (1 mg QD) to 3.3 log(10) IU/ml (10 mg QD in genotype 1b and 30 mg QD). E(max) modeling indicated GS-5885 30 mg was associated with>95% of maximal antiviral response to HCV genotype 1a. HCV RNA reductions were generally more sustained among patients with genotype 1b vs. 1a. Three of 60 patients had a reduced response and harbored NS5A-resistant virus at baseline. NS5A sequencing identified residues 30 and 31 in genotype 1a, and 93 in genotype 1b as the predominant sites of mutation following GS-5885 dosing. Plasma pharmacokinetics was consistent with QD dosing. Synonyms: GS-5885 diacetone; GS 5885 diacetone; GS5885 diacetone. Grades: >98%. CAS No. 1502655-48-2. Molecular formula: C55H66F2N8O8. Mole weight: 1005.16. | |
| Ledipasvir D-tartrate | Against JFH1/3a-NS5A, DCV was more potent (EC(50) = 0.52 nM) than GS-5885 (EC(50) = 141 nM). DCV sensitivity was increased against JFH1/3a-NS5A-M28V (EC50 = 0.006 nM), A30V (EC(50) = 0.012 nM), and E92A (EC(50) = 0.004 nM) while the NS5A-A30K and -Y93H variants exhibited reduced sensitivity to DCV (EC50 values of 23 nM and 1120 nM, respectively) and to GS-5885 (EC50 values of 1770 nM and 4300 nM, respectively). GS-5885 was well tolerated and resulted in median maximal reductions in HCV RNA ranging from 2.3 log(10) IU/ml (1 mg QD) to 3.3 log(10) IU/ml (10 mg QD in genotype 1b and 30 mg QD). E(max) modeling indicated GS-5885 30 mg was associated with>95% of maximal antiviral response to HCV genotype 1a. HCV RNA reductions were generally more sustained among patients with genotype 1b vs. 1a. Three of 60 patients had a reduced response and harbored NS5A-resistant virus at baseline. NS5A sequencing identified residues 30 and 31 in genotype 1a, and 93 in genotype 1b as the predominant sites of mutation following GS-5885 dosing. Plasma pharmacokinetics was consistent with QD dosing. Synonyms: GS-5885 D-tartrate; GS 5885 D-tartrate; GS5885 D-tartrate. Grades: >98%. CAS No. 1502654-87-6. Molecular formula: C53H60F2N8O12. Mole weight: 1039.09. | |
| Ledipasvir D-tartrate | Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A , with EC 50 values of 34 pM against GT1a and 4 pM against GT1b replicon. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5885 D-tartrate. CAS No. 1502654-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15602B. | |
| Ledipasvir Impurity 1 | Grades: > 95%. Molecular formula: C24H34BN3O4. Mole weight: 439.37. | |
| Ledipasvir Impurity 2 | Grades: > 95%. Molecular formula: C24H34BN3O4. Mole weight: 439.37. | |
| (1R, 3S, 4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2. 2. 1]heptane-3-carboxylic Acid | (1R, 3S, 4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2. 2. 1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-?daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants. Group: Biochemicals. Grades: Highly Purified. CAS No. 291775-59-2. Pack Sizes: 250mg, 1g. Molecular Formula: C12H19NO4, Molecular Weight: 241.28. US Biological Life Sciences. |  Worldwide |
| (2-((1R, 3S, 4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2. 2. 1]heptan-3-yl)-1H-benzo[d]imidazol-5-yl)boronic Acid | (2-((1R, 3S, 4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2. 2. 1]heptan-3-yl)-1H-benzo[d]imidazol-5-yl)boronic Acid can be obtained from (1R, 3S, 4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2. 2. 1]heptane-3-carboxylic Acid (B694100) which is a building block in the synthesis of Ledipasvir, a potent, once-?daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H24BN3O4, Molecular Weight: 357.21. US Biological Life Sciences. | Worldwide |
| 2-Amino-4'-bromoacetophenone Hydrochloride | 2-Amino-4'-bromoacetophenone Hydrochloride is used as a reagent in the synthesis of Ledipasvir (L320100); a potent, once-daily oral NS5A inhibitor used for treatment of hepatitis C virus infection. 2-Amino-4'-bromoacetophenone Hydrochloride is also used in the preparation of the β-receptor agonists (-)-Denopamine (D231485) and (-)-Arbutamine (A766300). Group: Biochemicals. Grades: Highly Purified. CAS No. 5467-72-1. Pack Sizes: 250mg, 1g. Molecular Formula: C8H9BrClNO, Molecular Weight: 250.52. US Biological Life Sciences. | Worldwide |
| [(2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl]methyl Benzoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: benzoic acid [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxo-2-oxolanyl]methyl ester; [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxooxolan-2-yl]methyl benzoate. Grades: 99 %. CAS No. 874638-80-9. Molecular formula: C20H17FO6. Mole weight: 372.34. | |
| ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methyltetrahydrofuran-2-yl)methyl benzoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidine-1(2H)-yl )-4-methyltetrahydrofuran-2-pyridin-3-yl)methyl benzoate. Grades: 98%. CAS No. 1496551-71-3. Molecular formula: C24H21ClN2O7. Mole weight: 484.89. | |
| (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-chloro-4-methyltetrahydrofuran-3-yl benzoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxopyrimidine-1(2H)-yl)-2-((benzoyloxy)methyl)-4-Chloro-4-methyltetrahydrofuran-3-ylbenzoate. Grades: 95%. CAS No. 1496551-70-2. Molecular formula: C31H26ClN3O7. Mole weight: 588.01. | |
| (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-hydroxy-4-methyltetrahydrofuran-3-yl benzoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: 95%. CAS No. 863329-64-0. Molecular formula: C31H27N3O8. Mole weight: 569.56. | |
| (2S)-Isopropyl 2- ( ( (perfluorophenoxy) (phenoxy)phosphoryl)amino)propanoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Propan-2-yl (2S) -2-{[pentafluorophenoxy (phenoxy) phosphoryl]amino}propanoate; N-[ (S) - (2, 3, 4, 5, 6-Pentafluorophenoxy) Phenoxyphosphinyl]-L-Alanine 1-Methylethyl Ester; N-[ (S) - (2, 3, 4, 5, 6-Pentafluorophenoxy) phenoxyphosphinyl]-L-alanine1-methylethyl ester. CAS No. 1256490-52-4. Molecular formula: C18H17F5NO5P. Mole weight: 453.302. | |
| MOC-L-Valine | MOC-L-valine (S)-2-((methoxycarbonyl) amino)-3-methylbutyric acid, a key synthetic intermediate of ledipasvir, is indicated for the treatment of chronic hepatitis C Virus (HCV) infection in adults and adolescents aged 12 to <18 years. CAS No. 74761-42-5. Product ID: PAP-0015. Molecular formula: C7H13NO4. Category: Amino acid. Product Keywords: Amino Acid Series; MOC-L-Valine; PAP-0015; Amino acid; C7H13NO4; 74761-42-5. Color: White to Almost white. Physical State: powder to crystal. Storage: Sealed in dry,Room Temperature. Applications: Moc-l-valine, also known as (S)-2-((methoxycarbonyl) amino) -3-methylbutyric acid, is a key synthetic intermediate for the treatment of chronic hepatitis C virus (HCV) infection in adults and adolescents aged 12 to <18 years. Boiling Point: 315.9±25.0 °C(Predicted). Melting Point: 109.0 to 113.0 °C. Density: 1.154±0.06 g/cm3(Predicted). Product Description: Moc-l-valine, also known as (S)-2-((methoxycarbonyl) amino) -3-methylbutyric acid, is a key synthetic intermediate for the treatment of chronic hepatitis C virus (HCV) infection in adults and adolescents aged 12 to <18 years. |  |
| Sofosbuvir Impurity 1 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2R,3R,4S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate; N4,3',5'-Tribenzoyl,2'-deoxy-2'β-fluoro-2'C-α-methyl Cytidine. Grades: > 95%. Molecular formula: C31H26FN3O7. Mole weight: 571.55. | |
| Sofosbuvir Impurity 10 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Uridine, 2'-deoxy-2'-methylene-, 3',?5'-dibenzoate. Grades: > 95%. CAS No. 1910099-17-0. Molecular formula: C24H20N2O7. Mole weight: 448.42. | |
| Sofosbuvir Impurity 11 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-epi-Sofosbuvir Desphosphate. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Sofosbuvir Impurity 12 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-c-methyl arabino-uridine; 1-(2-C-Methyl-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: > 95%. CAS No. 114262-49-6. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| Sofosbuvir Impurity 13 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Methylene-2'-deoxyuridine; 2'-Methylidene-2'-deoxyuridine; 2'-Deoxy-2'-methyleneuridine. Grades: > 95%. CAS No. 119410-95-6. Molecular formula: C10H12N2O5. Mole weight: 240.22. | |
| Sofosbuvir Impurity 14 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46. | |
| Sofosbuvir Impurity 15 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Defluro-2'-hydroxy 2'-epi-Sofosbuvir. Grades: > 95%. Molecular formula: C22H30N3O10P. Mole weight: 527.46. | |
| Sofosbuvir Impurity 16 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Defluro-2'-methylene Sofosbuvir. Grades: > 95%. Molecular formula: C22H28N3O9P. Mole weight: 509.45. | |
| Sofosbuvir Impurity 17 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C34H45FN4O13P2. Mole weight: 798.7. | |
| Sofosbuvir Impurity 2 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Benzamide, N-[1-(3,5-di-O-benzoyl-2-C-methyl-beta-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-. Grades: > 95%. CAS No. 863329-62-8. Molecular formula: C31H27N3O8. Mole weight: 569.56. | |
| Sofosbuvir Impurity 20 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2S)-Isopropyl 2- ( ( ( ( (2R, 3R, 4R, 5R) -5- (2, 4-Dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4-fluoro-2- (hydroxymethyl) -4-methyltetrahydrofuran-3-yl) oxy) (phenoxy) phosphoryl) amino) propanoate; Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]. Grades: > 95%. CAS No. 1337482-15-1. Molecular formula: C22H29FN3O9P. Mole weight: 529.46. | |
| Sofosbuvir Impurity 21 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Chloro (R)-Phosphoryl Sofosbuvir. Grades: > 95%. CAS No. 1496552-50-1. Molecular formula: C22H29ClN3O9P. Mole weight: 545.92. | |
| Sofosbuvir Impurity 22 (GS-491241) | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46. | |
| Sofosbuvir Impurity 23 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: α-Sofosbuvir Desphosphate. Grades: 98%. CAS No. 2041584-99-8. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Sofosbuvir Impurity 24 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Sofosbuvir Impurity 25 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Sofosbuvir Impurity 26 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Sofosbuvir Impurity 27 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Sofosbuvir Impurity 28 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Sofosbuvir Impurity 29 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: ent-Sofosbuvir Desphosphate. Grades: 98%. CAS No. 1946820-96-7. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Sofosbuvir Impurity 3 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C38H31N3O9. Mole weight: 673.69. | |
| Sofosbuvir Impurity 32 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-methyl-, γ-lactone, 3,?5-dibenzoate, (2S)?-. Grades: > 95%. CAS No. 1157884-58-6. Molecular formula: C20H17FO6. Mole weight: 372.34. | |
| Sofosbuvir Impurity 33 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: D-erythro-Pentonic acid, 2-chloro-2-deoxy-2-methyl-, γ-lactone, 3,?5-dibenzoate, (2R)?-. Grades: > 95%. CAS No. 1496551-65-5. Molecular formula: C20H17ClO6. Mole weight: 388.8. | |
| Sofosbuvir Impurity 34 (GS-606965) | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 5'-Uridylic acid, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)?-; (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic acid; PSI 7411. Grades: > 95%. CAS No. 1015073-43-4. Molecular formula: C10H14FN2O8P. Mole weight: 340.2. | |
| Sofosbuvir Impurity 35 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2'R)-2'-Chloro-2'-deoxy-2'-methyl-uridine; Chloro Sofosbuvir Desphosphate. Grades: > 95%. CAS No. 1496551-72-4. Molecular formula: C10H13ClN2O5. Mole weight: 276.68. | |
| Sofosbuvir Impurity 36 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H15FN2O11P2. Mole weight: 420.18. | |
| Sofosbuvir Impurity 37 ( Sofosbuvir Isomer) | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46. | |
| Sofosbuvir Impurity 38 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46. | |
| Sofosbuvir Impurity 39 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Benzamide, N-[1-[(2R)?-3,?5-di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]?-1,?2-dihydro-2-oxo-4-pyrimidinyl]?-; N-[1-[(2R)-3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide. Grades: 98%. CAS No. 874638-94-5. Molecular formula: C31H26FN3O7. Mole weight: 571.55. | |
| Sofosbuvir Impurity 4 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: N-Benzoyl-2'-deoxy-2'-methylenecytidine 3',5'-Dibenzoate; N4,3',5'-Tribenzoyl,2'-deoxy-2'-methylene Cytidine. Grades: > 95%. CAS No. 863329-63-9. Molecular formula: C31H25N3O7. Mole weight: 551.56. | |
| Sofosbuvir Impurity 40 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Des-alanyl Sofosbuvir. Grades: > 95%. Molecular formula: C16H18FN2O8P. Mole weight: 416.29. | |
| Sofosbuvir Impurity 41 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-1-(1-methylethyl) Ester L-Alanine; O-Desphenyl Sofosbuvir. Grades: > 95%. CAS No. 1233335-82-4. Molecular formula: C16H25FN3O9P. Mole weight: 453.36. | |
| Sofosbuvir Impurity 42 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C16H25FN3O9P. Mole weight: 453.36. | |
| Sofosbuvir Impurity 43 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: N-(Hydroxyphenoxyphosphinyl)-L-alanine 1-Methylethyl Ester Sodium Salt; (2S)-Isopropyl 2- ( (Hydroxy (phenoxy)phosphoryl)amino)propanoate Sodium Salt; Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt. Grades: > 95%. Molecular formula: C12H17NO5P. Na. Mole weight: 286.25 22.99. | |
| Sofosbuvir Impurity 5 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C24H22FN3O6. Mole weight: 467.46. | |
| Sofosbuvir Impurity 6 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C24H22FN3O6. Mole weight: 467.46. | |
| Sofosbuvir Impurity 7 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C24H21FN2O7. Mole weight: 468.44. | |
| Sofosbuvir Impurity 8 | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Uridine, 2'-C-methyl-, 3',?5'-dibenzoate. Grades: > 95%. CAS No. 944476-44-2. Molecular formula: C24H22N2O8. Mole weight: 466.44. | |
| Sofosbuvir Impurity (GS-566500) | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: L-Alanine, N-[(2'R)?-2'-deoxy-2'-fluoro-2'-methyl-5'-uridylyl]?-; N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-L-alanine; PSI 352707. Grades: > 95%. CAS No. 1233335-78-8. Molecular formula: C13H19FN3O9P. Mole weight: 411.28. | |
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