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| Product | Description | |
|---|---|---|
| Leptin (116-130) (human) | Leptin (116-130) (human) is a fragment of human leptin, which is an adipose tissue-derived protein encoded by an obesity gene and is involved in controlling food intake, energy expenditure and reproduction, as well as playing a role in immune regulation, inflammation, and hematopoiesis. Synonyms: Obese Gene Peptide (116-130) (human); L-Serine, L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-serylglycyl-L-leucyl-L-α-glutamyl-L-threonyl-L-leucyl-L-α-aspartyl-; H-Ser-Cys-His-Leu-Pro-Trp-Ala-Ser-Gly-Leu-Glu-Thr-Leu-Asp-Ser-OH; L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-seryl-glycyl-L-leucyl-L-alpha-glutamyl-L-threonyl-L-leucyl-L-alpha-aspartyl-L-serine. Grades: ≥95%. CAS No. 2243207-12-5. Molecular formula: C70H106N18O24S. Mole weight: 1615.76. |  |
| Leptin(150-167)(human) | Leptin(150-167)(human). Uses: Designed for use in research and industrial production. Additional or Alternative Names: LEU-GLN-GLY-SER-LEU-GLN-ASP-MET-LEU-TRP-GLN-LEU-ASP-LEU-SER-PRO-GLY-CYS;LEPTIN (150-167) (HUMAN);LEPTIN FRAGMENT 150-167 HUMAN;H-LEU-GLN-GLY-SER-LEU-GLN-ASP-MET-LEU-TRP-GLN-LEU-ASP-LEU-SER-PRO-GLY-CYS-OH;OBESE GENE PEPTIDE (150-167) (HUMAN);Obese Gene. Product Category: Heterocyclic Organic Compound. CAS No. 200436-46-0. Molecular formula: C87H138N22O28S2. Mole weight: 2004.29. Purity: 0.96. IUPACName: LEPTIN (150-167) (HUMAN). Canonical SMILES: CC(C)CC(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCSC)C(=O)NC(CC(C)C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)N3CCCC3C(=O)NCC(=O)NC(CS)C(=O)O)N. Product ID: ACM200436460. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Leptin (22-56), human | Leptin (22-56) (human) is the fragment of leptin, a hormone produced by the fat cells in human body. Synonyms: H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH; L-valyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-lysyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-alpha-aspartyl-L-threonyl-L-lysyl-L-threonyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-isoleucyl-L-valyl-L-threonyl-L-arginyl-L-isoleucyl-L-asparagyl-L-alpha-aspartyl-L-isoleucyl-L-seryl-L-histidyl-L-threonyl-L-glutaminyl-L-seryl-L-valyl-L-seryl-L-seryl-L-lysyl-L-glutaminyl-L-lysine. Grades: >95%. CAS No. 183598-56-3. Molecular formula: C171H298N50O56. Mole weight: 3950.49. | |
| Leptin Fragment 116-130 Amide mouse | A synthetic leptin peptide fragment. Synonyms: LEP 116-130. Grades: >95%. CAS No. 258276-95-8. Molecular formula: C64H109N19O24S. Mole weight: 1560.73. | |
| Leptin (human) | Leptin (human) is a peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Synonyms: 1: PN: WO0038651 SEQID: 1 unclaimed protein; 22-167-Protein (human gene obese 167-amino acid isoform precursor); Anti-obesity protein (human); Leptin (human clone 3 gene Ob); Leptin (human gene ob protein 146-amino acid fragment); Leptin (synthetic human mutant 15B); Protein (human gene ob active isoform). Grades: ≥95% by HPLC. CAS No. 177404-21-6. | |
| rec Leptin (human) | Leptin is an adipose tissue-derived protein encoded by an obesity gene and is involved in controlling food intake, energy expenditure and reproduction, as well as playing a role in immune regulation, inflammation, and hematopoiesis. Synonyms: rec Obesity Factor (human); OB gene product; OB Protein; Obesity Protein; OBS; Obesity factor; Leptin (human), (recombinant). | |
| rec Leptin (mouse) | Leptin is an adipose tissue-derived protein encoded by an obesity gene and is involved in controlling food intake, energy expenditure and reproduction, as well as playing a role in immune regulation, inflammation, and hematopoiesis. Synonyms: rec Obesity Factor (mouse). CAS No. 1061787-61-8. | |
| 1,2-Distearoyl-3-oleoyl-rac-glycerol | 1,2-Distearoyl-3-oleoyl-rac-glycerol is used in the study of leptin resistance at the blood-brain barrier. Group: Biochemicals. Grades: Highly Purified. CAS No. 2190-29-6. Pack Sizes: 50mg, 500mg. Molecular Formula: C57H108O6, Molecular Weight: 889.46. US Biological Life Sciences. |  Worldwide |
| 1,2-Distearoyl-3-oleoyl-rac-glycerol-d5 | 1,2-Distearoyl-3-oleoyl-rac-glycerol-d5 is labelled 1,2-Distearoyl-3-oleoyl-rac-glycerol (D493520) which is used in the study of leptin resistance at the blood-brain barrier. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C57H103D5O6, Molecular Weight: 894.49. US Biological Life Sciences. | Worldwide |
| Acipimox | Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K-9321. CAS No. 51037-30-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0283. |  |
| CART(55-102)(human) | CART(55-102)(human) is an endogenous satiety factor with potent appetite-suppressing activity. CART(55-102)(human) is closely associated with leptin and neuropeptide Y [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 214050-22-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1304. | |
| Cerulenin (2,3-Epoxy-4-oxo-7,10-dodecadienamide) | Antibiotic. Fatty acid synthase (FAS) inhibitor, reported to bind in equimolar ratio to B-keto-acyl- ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes). Group: Biochemicals. Grades: Highly Purified. CAS No. 17397-89-6. Pack Sizes: 5mg. Molecular Formula:C12H17NO3 MOLECULAR WEIGHT: 223.3. US Biological Life Sciences. | Worldwide |
| Galanin-Like Peptide (porcine) | Galanin-Like Peptide (porcine) is a GALR2 (galanin receptor)-binding neuropeptide isolated from porcine hypothalamus. It is an endogenous ligand that preferentially binds to GALR2 receptors and plays a role in regulating the effects of leptin, a satiety hormone. It is a potent vasoactive peptide and is thought to be involved in inflammatory responses. Synonyms: GALP (porcine); H-Ala-Pro-Val-His-Arg-Gly-Arg-Gly-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Val-Leu-His-Pro-Pro-Ser-Arg-Ala-Glu-Gly-Gly-Gly-Lys-Gly-Lys-Thr-Ala-Leu-Gly-Ile-Leu-Asp-Leu-Trp-Lys-Ala-Ile-Asp-Gly-Leu-Pro-Tyr-Pro-Gln-Ser-Gln-Leu-Ala-Ser-OH. Grades: 95%. CAS No. 245114-96-9. Molecular formula: C281H443N81O78. Mole weight: 6204.02. | |
| LEP (116-130) (mouse) TFA | LEP (116-130) (mouse) TFA is a synthetic leptin peptide fragment. Synonyms: Leptin Fragment 116-130 Amide mouse TFA; LEP(116-130) (mouse) TFA; H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2.TFA; L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-seryl-glycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-serinamide trifluoroacetic acid; L-Serinamide, L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-serylglycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-α-glutamyl-, 2,2,2-trifluoroacetate (1:1). Grades: ≥95%. CAS No. 2828433-16-3. Molecular formula: C66H110F3N19O26S. Mole weight: 1674.77. | |
| Oleuropein Aglycone | Oleuropein Aglycone (3,4-DHPEA-EA) is a polyphenol and the aglycone form of oleuropein (HY-N0292), formed by enzymatic, acidic or acetylated hydrolysis of oleuropein. Dietary intake of oleuropein Aglycone (50 mg/kg diet) increases the number of neuronal autophagic vesicles, reverses cognitive deficits in the TgCRND8 transgenic mouse model of Alzheimer's disease, and reduces the levels of histone deacetylase 2 ( HDAC2 ) in the cortex and hippocampus. Oleuropein Aglycone increases urinary norepinephrine, interscapular brown adipose tissue epinephrine, and UCP1 protein levels, and reduced plasma leptin levels and total abdominal adipose tissue weight in a rat model of high-fat diet-induced obesity. Oleuropein Aglycone also reduced lung neutrophil infiltration, lipid peroxidation, and IL-1β levels in a mouse model of carrageenan-induced pleurisy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,4-DHPEA-EA. CAS No. 31773-95-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135115. | |
| Phyllodulcin | Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21499-23-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W044525. | |
| SR 27897 | SR 27897 is a potent and non-peptide CCK1 receptor antagonist displaying > 33-fold selectivity over CCK2 receptors (EC50 = 6 and 200 nM, respectively). It was shown to increase plasma leptin levels and promote food intake in rats in vivo. SR 27897 is used for the treatment of pancreatic cancer. Uses: The treatment of pancreatic cancer. Synonyms: SR-27897; SR27897; SR 27897; 2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid; Lintitript. Grades: ≥99% by HPLC. CAS No. 136381-85-6. Molecular formula: C20H14ClN3O3S. Mole weight: 411.86. | |
| Stavudine sodium | Stavudine sodium is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. Stavudine sodium is an analog of thymidine. It is phosphorylated by cellular kinases into active triphosphate. Stavudine sodium triphosphate inhibits the HIV reverse transcriptase by competing with natural substrate, thymidine triphosphate. It also causes termination of DNA synthesis by incorporating into it. Mice were treated for 2 weeks with stavudine d4T (500 mg/kg/day), L-carnitine (200 mg/kg/day) or both drugs concomitantly. Body fatness was assessed by dual energy X-ray absorptiometry, and investigations were performed in plasma, liver, muscle and WAT. D4T reduced the gain of body adiposity, WAT leptin, whole body FAO and plasma ketone bodies, and increased liver triglycerides and plasma aminotransferases with mild ultrastructural abnormalities in hepatocytes. Synonyms: Zerit sodium; d4T sodium. Grades: >98%. CAS No. 134624-73-0. Molecular formula: C10H11N2NaO4. Mole weight: 246.2. | |
| ZD 2079 | ZD 2079 is a β3-adrenoceptor agonist. ZD 2079 inhibits ob gene expression and circulating leptin levels in lean mice in vivo, and has the potential to treat obesity and type 2 diabetes. Uses: Potential treatment of obesity and type ii diabetes. Synonyms: 4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethoxy]-benzeneacetic acid hydrochloride; Talibegron hydrochloride; Talibegron HCl, Talibegron hydrochloride, D-2079, ICI-D-2079, SCH-417849, ZD-2079, D2079, ICI-D2079, SCH417849, ZD2079. Grades: ≥99% by HPLC. CAS No. 178600-17-4. Molecular formula: C18H21NO4.HCl. Mole weight: 351.83. | |
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