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1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H11N5. CAS No. 112809-51-5. Prepack ID 36941533-1g. Molecular Weight 285.3. See USA prepack pricing.
Letrozole
A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic. An orally bioavailable non-steroidal triazole compound that acts as a potent and selective inhibitor of aromatase (IC50=140, 350 and 450pM in Dex-treated fibroblasts, MCF-7Ca, and JEG-3 cells, respectively). Competitively, but reversibly binds to the heme iron of aromatase. Does not affect the synthesis of adrenal mineralocorticoid or glucocorticoids. Reported to be highly effective as an anti-estrogenic and anti-proliferative agent in estrogen-rich tumors. Also delays the fusing of the growth plates in adolescents and enhances the effectiveness of growth hormone. Shown to synergistically induce apoptosis and cause tumor regression when combined with IGF-1R inhibitors. Group: Biochemicals. Alternative Names: 4, 4- (1H-1, 2, 4-Triazol-1-ylmethylene) bisbenzonitrile; 4-[1- (4-Cyanophenyl) -1- (1, 2, 4-triazol-1-yl) methyl]benzonitrile; CGS 20267; Femara; Lerozole; Letrazole; Aromatase Inhibitor II. Grades: Highly Purified. CAS No. 112809-51-5. Pack Sizes: 1g, 5g. Molecular Formula: C17H11N5, Molecular Weight: 285.3. US Biological Life Sciences.
Worldwide
Letrozole
Letrozole. CAS No. 112809-51-5. Product ID: 2-08292. Molecular formula: C17H11N5. Mole weight: 285.1. Purity: 99% (HPLC). Properties: Off white to white crystal mp 181--183°C LOD ≤0.3% Related substances ≤0.5%.
Letrozole
Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase , with an IC 50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: CGS 20267. CAS No. 112809-51-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-14248.
Letrozole-d4
A deuterated version of Letrozole, a nonsteroidal aromatase inhibitor structurally related to Fadrozole.The current lot is 84% d4, 16% d3, no detectable d2, d1 or d0. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Letrozole EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113402-31-6. Molecular Formula: C22H13N3. Mole Weight: 319.37. Catalog: APB113402316.
Letrozole Impurity 10
Letrozole Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-fluorobenzonitrile. CAS No. 394-47-8. Molecular Formula: C7H4FN. Mole Weight: 121.11. Catalog: APB394478.
Letrozole Impurity 9
Letrozole Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-fluorobenzonitrile. CAS No. 403-54-3. Molecular Formula: C7H4FN. Mole Weight: 121.11. Catalog: APB403543.
an intermediate in the synthesis of Letrozole. Synonyms: 4-(1H-1,2,4-Triazol-1-ylmethyl)benzonitrile; 1-(4-Cyanobenzyl)-1,2,4-triazole. Grades: > 95%. CAS No. 112809-25-3. Molecular formula: C10H8N4. Mole weight: 184.20.
Letrozole Impurity E
an impurity of Letrozole. Synonyms: 4-Descyano-4-bromo-letrozole; 4-[(4-Bromophenyl)-1H-1,2,4-triazol-1-ylmethyl]benzonitrile. Grades: > 95%. CAS No. 143030-54-0. Molecular formula: C16H11BrN4. Mole weight: 339.20.
an impurity of Letrozole. Synonyms: 4,4'-(4H-1,2,4-Triazol-4-ylmethylene)bisbenzonitrile; Iso Letrozole. Grades: > 95%. CAS No. 112809-52-6. Molecular formula: C17H11N5. Mole weight: 285.31.
4,4',4''-Methylidynetrisbenzonitrile (Letrozole Impurity). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Letrozole Impurity B. CAS No. 113402-31-6. IUPAC Name: 4-[bis(4-cyanophenyl)methyl]benzonitrile. Molecular Formula: C22H13N3. Mole Weight: 319.36. Catalog: APS113402316. Format: Neat.
Iso Letrozole
Iso Letrozole. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Letrozole USP RC A, Letrozole USP Related Compound A, 4,4'-(4H-1,2,4-Triazol-4-ylmethylene)dibenzonitrile,Letrozole Imp. A (EP). CAS No. 112809-52-6. IUPAC Name: 4-[(4-cyanophenyl)-(1,2,4-triazol-4-yl)methyl]benzonitrile. Molecular Formula: C17H11N5. Mole Weight: 285.30. Catalog: APS112809526. SMILES: N#Cc1ccc(cc1)C(c2ccc(cc2)C#N)n3cnnc3. Format: Neat.
4-(1H-1,2,4-Triazolylmethyl)benzonitrile
4-(1H-1,2,4-Triazolylmethyl)benzonitrile. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZONITRILE;4-(1H-1,2,4-TRIAZOLYLMETHYL)BENZONITRILE;4-[1-(1,2,4-triazolyl)-methyl-benzonitrile;4-1-(1,2,4-Triazolyl)-methyl-benzonitril;4-((1H-1,2,4-triazol-1-yl)methyl)benzonitrile (intermediate of letrozole);4-(1H-1,2,4. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 112809-25-3. Molecular formula: C10H8N4. Mole weight: 184.2. Purity: 0.98. Density: 1.19 g/cm³. Product ID: ACM112809253. Alfa Chemistry ISO 9001:2015 Certified.
4,4'-(Hydroxymethylene)dibenzonitrile
A metabolite of Letrozole. Synonyms: Bis(4-cyanophenyl)methanol; 4,4'-Dicyanobenzhydrol. Grades: 92 %. CAS No. 134521-16-7. Molecular formula: C15H10N2O. Mole weight: 234.25.
Palbociclib Impurity 12
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: tert-butyl 4-(6-((2-chloro-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)amino)pyridin-3-yl)piperazine-1-carboxylate. Grades: > 95%. Molecular formula: C27H34ClN7O3. Mole weight: 540.07.
Palbociclib Impurity 13
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 2-acetyl-8-cyclopentyl-5-methyl-6-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one. Grades: > 95%. Molecular formula: C24H29N7O2. Mole weight: 447.54.
Palbociclib Impurity 7
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 1-Piperazinecarboxylic acid, 4-[6-[[6-[(1E)?-2-butoxyethenyl]?-8-cyclopentyl-7,?8-dihydro-5-methyl-7-oxopyrido[2,?3-d]?pyrimidin-2-yl]?amino]?-3-pyridinyl]?-, 1,?1-dimethylethyl ester. Grades: > 95%. CAS No. 827022-35-5. Molecular formula: C33H45N7O4. Mole weight: 603.77.
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