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| Product | Description | |
|---|---|---|
| Leukotriene a3 methyl ester | Leukotriene a3 methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5S-TRANS-5,6-OXIDO-7E,9E,11Z-EICOSATRIENOIC ACID, METHYL ESTER;LTA3 METHYL ESTER;LEUKOTRIENE A3 METHYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 83851-38-1. Molecular formula: C21H34O3. Mole weight: 334.49. Purity: 0.96. IUPACName: methyl4-[(2S,3S)-3-[(1E,3E,5Z)-tetradeca-1,3,5-trienyl]oxiran-2-yl]butanoate. Canonical SMILES: CCCCCCCCC=CC=CC=CC1C(O1)CCCC(=O)OC. Density: 0.985g/cm³. Product ID: ACM83851381. Alfa Chemistry ISO 9001:2015 Certified. |  |
| leukotriene-A4 hydrolase | This is a bifunctional zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities. It preferentially cleaves tripeptides at an arginyl bond, with dipeptides and tetrapeptides being poorer substrates (see EC 3.4.11.6, aminopeptidase B). It also converts leukotriene A4 into leukotriene B4, unlike EC 3.3.2.10, soluble epoxide hydrolase, which converts leukotriene A4 into 5,6-dihydroxy-7,9,11,14-icosatetraenoic acid. In vertebrates, five epoxide-hydrolase enzymes have been identified to date: EC 3.3.2.6 (leukotriene A4 hydrolase), EC 3.3.2.7 (hepoxilin-epoxide hydrolase), EC 3.3.2.9 (microsomal epoxide hydrolase), EC 3.3.2.10 (soluble epoxide hydrolase) and EC 3.3.2.11 (cholesterol-5,6-oxide hydrolase). Group: Enzymes. Synonyms: LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase. Enzyme Commission Number: EC 3.3.2.6. CAS No. 90119-07-6. LTA4H. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4003; leukotriene-A4 hydrolase; EC 3.3.2.6; 90119-07-6; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase. Cat No: EXWM-4003. |  |
| Leukotriene A4 Hydrolase from Human, Recombinant | Leukotriene A4 Hydrolase human (LTA4H) is a bifunctional zinc metalloenzyme that converts LTA4 into Leukotriene B4, and also demonstrates aminopeptidase activity. Leukotriene B4 is a lipid chemoattractant that plays critical roles in inflammaton, immune responses, host defenses against infections, and lipid homeostasis. Inhibition of LTA4H in a mouse model decreases LTB4 in the airways and attenuates airway inflammation and airway hyperreactivity through modulation of T cell and dendritic cell function. Contains c-terminal his-tag. Applications: Leukotriene a4 hydrolase human (lta4h) is a drug target for anti-inflammation, and for cancer prevention and therapy. it is also suitable for screening inhibitors of leukotriene b4 synthesis. lta4h is used to study allergic asthma and airway hyperresponsiveness. Group: Enzymes. Synonyms: leukotriene-A4 hydrolase; LTA-4 hydrolase; LTA4; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase; EC 3.3.2.6; 90119-07-6. Enzyme Commission Number: EC 3.3.2.6. CAS No. 90119-07-6. LTA4H. Mole weight: mol wt ~69 kDa. Storage: -70°C. Form: Supplied as a solution in 100mM Tris, pH 8.0, containing 20% glycerol and 100mM potassium chloride. Source: E. coli. Species: Human. leukotriene-A4 hydrolase; LTA-4 hydrolase; LTA4; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase; EC 3.3.2.6; 90119-07-6. Cat No: NATE-0419. | |
| Leukotriene B | Leukotriene B4 is a chemokine with roles in inflammation, immunology, the nervous system, brain and skin. And it also shows antiviral activity towards DNA viruses and retroviruses. Synonyms: Leukotriene B4; LTB4; 5,12-Hete; 5,12-Dihete; (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid. Grades: ≥98%. CAS No. 71160-24-2. Molecular formula: C20H32O4. Mole weight: 336.47. |  |
| Leukotriene B4 | Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LTB4; 5(S),12(R)-DiHETE. CAS No. 71160-24-2. Pack Sizes: 25 μg (297.2 μM * 250 μL in Ethanol). Product ID: HY-107608. |  |
| leukotriene-B4 20-monooxygenase | A heme-thiolate protein (P-450). Not identical with EC 1.14.13.34, leukotriene-E4 20-monooxygenase. Group: Enzymes. Synonyms: leukotriene-B4 20-hydroxylase; leucotriene-B4 ω-hydroxylase; LTB4 20-hydroxylase; LTB4 ω-hydroxylase. Enzyme Commission Number: EC 1.14.13.30. CAS No. 90119-11-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0837; leukotriene-B4 20-monooxygenase; EC 1.14.13.30; 90119-11-2; leukotriene-B4 20-hydroxylase; leucotriene-B4 ω-hydroxylase; LTB4 20-hydroxylase; LTB4 ω-hydroxylase. Cat No: EXWM-0837. | |
| Leukotriene B4-3-aminopropylamide | Leukotriene B4-3-aminopropylamide is a LTB4 analog that exhibits high binding affinity for BLT1 receptor. Synonyms: LTB4-3-aminopropylamide; (5S,6Z,8E,10E,12R,14Z)-N-(3-aminopropyl)-5,12-dihydroxyicosa-6,8,10,14-tetraenamide. Grades: ≥95%. CAS No. 89596-43-0. Molecular formula: C23H40N2O3. Mole weight: 392.6. | |
| Leukotriene B4 dimethyl amide | Leukotriene B4 dimethyl amide is a lipid mediator and Leukotriene B4 antagonist. It was shown to inhibit neutrophil degranulation induced by LTB4. Synonyms: LTB4 dimethyl amide; N,N-dimethyl-5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraen-1-amide. Grades: ≥97%. CAS No. 83024-92-4. Molecular formula: C22H37NO3. Mole weight: 363.5. | |
| Leukotriene B4 ethanolamide | Leukotriene B4 ethanolamide is a potent antagonist of leukotriene B4 receptor with 3-fold higher affinity than leukotriene B4. It exhibits anti-inflammatory activity. Synonyms: LTB4-EA; (5S,12R)-5,12-Dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide. Grades: ≥97%. CAS No. 877459-63-7. Molecular formula: C22H37NO4. Mole weight: 379.5. | |
| Leukotriene B5 | Leukotriene B5 is a leukotriene generated from eicosapentaenoic acid (EPA). LTB5 exhibits less potent biological activity than LTB4, thus it can be identified as a LTB4 antagonist. Study showed that LTB5 inhibited LTB4-induced chemotaxis in vitro and LTB4-induced proliferation in cultured human epidermal keratinocytes. Synonyms: LTB5; 5,12-DiHEPE; 5S,12S-dihydroxy-6Z,8E,14Z,17Z-eicosapentanenoic acid. Grades: ≥98%. CAS No. 80445-66-5. Molecular formula: C20H30O4. Mole weight: 334.5. | |
| Leukotriene c3 | Leukotriene c3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Leukotriene C-3, Leukotriene C3, PDSP1_000718, PDSP2_000708, CID6438868, 5-Hydroxy-6-S-glutathionyl-7,9,11-eicosatrienoic acid, 77209-77-9, Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6-pentadecatrienyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z)))-. Product Category: Heterocyclic Organic Compound. CAS No. 77209-77-9. Molecular formula: C31H51N3O8S. Mole weight: 625.82. Purity: 0.96. IUPACName: (5S,7E,9E,11E)-6-[(2R)-2-[[(4S)-4-amino-5-hydroxy-5-oxopentanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11-trienoic acid. Product ID: ACM77209779. Alfa Chemistry ISO 9001:2015 Certified. Categories: Leukotriene C4 synthase. | |
| Leukotriene C4 | Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4; 5S,6R-Ltc(sub 4); 6R-(((R)-2-((S)-4-amino-4-carboxybutanamido)-3-((carboxymethyl)amino)-3-oxopropyl)thio)-5S-hydroxyicosa-7E,9E,11Z,14Z-eicosatetraenoic acid. Grades: ≥97%. CAS No. 72025-60-6. Molecular formula: C30H47N3O9S. Mole weight: 625.78. | |
| Leukotriene C4 | Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 72025-60-6. Pack Sizes: 25 μg (159.8 μM * 250 μL in Ethanol). Product ID: HY-113446. | |
| LEUKOTRIENE C4 | LEUKOTRIENE C4. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Leukotriene C4 Lipid. Appearance: Colorless liquid. CAS No. 72025-60-6. Molecular formula: C30H47N3O9S. Mole weight: 625.77. Purity: 0.97. Product ID: ACM72025606. Alfa Chemistry ISO 9001:2015 Certified. Categories: Leukotriene C4 synthase. | |
| leukotriene-C4 hydrolase | The mouse enzyme is specific for leukotriene C4, while the human enzyme also has considerable activity towards glutathione and oxidized glutathione (cf. EC 3.4.19.13, glutathione hydrolase). Group: Enzymes. Synonyms: γ-glutamyl leukotrienase; GGT5. Enzyme Commission Number: EC 3.4.19.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4086; leukotriene-C4 hydrolase; EC 3.4.19.14; γ-glutamyl leukotrienase; GGT5. Cat No: EXWM-4086. | |
| Leukotriene C4 methyl ester | Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4 methyl ester; Leukotriene C4 monomethyl ester. Grades: ≥97%. CAS No. 73958-10-8. Molecular formula: C31H49N3O9S. Mole weight: 639.8. | |
| leukotriene-C4 synthase | The reaction proceeds in the direction of addition. Not identical with EC 2.5.1.18, glutathione transferase. Group: Enzymes. Synonyms: leukotriene C4 synthetase; LTC4 synthase; LTC4 synthetase; leukotriene A4:glutathione S-leukotrienyltransferase; (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathioneleukotriene-transferase (epoxide-ring-opening); (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming). Enzyme Commission Number: EC 4.4.1.20. CAS No. 90698-32-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5322; leukotriene-C4 synthase; EC 4.4.1.20; 90698-32-1; leukotriene C4 synthetase; LTC4 synthase; LTC4 synthetase; leukotriene A4:glutathione S-leukotrienyltransferase; (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathioneleukotriene-transferase (epoxide-ring-opening); (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming). Cat No: EXWM-5322. | |
| Leukotriene D4 | Leukotriene D4 is a constituent of slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. Synonyms: Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-; Glycine, N-[S-[1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl]-L-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-; Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-; S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinylglycine; Leukotriene D; LTD4. Grades: ≥97%. CAS No. 73836-78-9. Molecular formula: C25H40N2O6S. Mole weight: 496.66. | |
| Leukotriene D4 | Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 73836-78-9. Pack Sizes: 10 μg (201.34 μM * 100 μL in Ethanol); 50 μg (201.34 μM * 500 μL in Ethanol). Product ID: HY-113456. | |
| Leukotriene D4 methyl ester | Leukotriene D4 methyl ester is a derivate of Leukotriene D4, which is a constituent of a slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. Synonyms: LTD4 methyl ester; Leukotriene D4 monomethyl ester; Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-hydroxy-5-methoxy-5-oxopentyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-; Glycine, N-[S-[1-(1-hydroxy-5-methoxy-5-oxopentyl)-2,4,6,9-pentadecatetraenyl]-L-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-; S-((5S,6R,7E,9E,11Z,14Z)-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl)-L-cysteinylglycine. Grades: 95%. CAS No. 103476-23-9. Molecular formula: C26H42N2O6S. Mole weight: 510.69. | |
| Leukotriene E4 | Leukotriene E4 is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma. Synonyms: 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid; LTE4. Grades: ≥97%. CAS No. 75715-89-8. Molecular formula: C23H37NO5S. Mole weight: 439.61. | |
| Leukotriene E4 | Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma. Uses: Scientific research. Group: Natural products. Alternative Names: LTE4. CAS No. 75715-89-8. Pack Sizes: 25 μg (227.47 μM * 250 μL in Ethanol); 50 μg (227.47 μM * 500 μL in Ethanol); 100 μg (227.47 μM * 1 mL in Ethanol). Product ID: HY-113465. | |
| leukotriene-E4 20-monooxygenase | Also acts on N-acetyl-leukotriene E4, but more slowly. Not identical with EC 1.14.13.30 leukotriene-B4 20-monooxygenase. Group: Enzymes. Synonyms: leukotriene-E4 ω-hydroxylase. Enzyme Commission Number: EC 1.14.13.34. CAS No. 111940-51-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0841; leukotriene-E4 20-monooxygenase; EC 1.14.13.34; 111940-51-3; leukotriene-E4 ω-hydroxylase. Cat No: EXWM-0841. | |
| Leukotriene E4 methyl ester | Leukotriene E4 methyl ester is a derivate of Leukotriene E4, which is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma. Synonyms: 7,9,11,14-Eicosatetraenoic acid, 6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-, 1-methyl ester, (5S,6R,7E,9E,11Z,14Z)-; 1-Methyl (5S,6R,7E,9E,11Z,14Z)-6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-7,9,11,14-eicosatetraenoate; 7,9,11,14-Eicosatetraenoic acid, 6-[(2-amino-2-carboxyethyl)thio]-5-hydroxy-, 1-methyl ester, [5S-[5R*,6S*(S*),7E,9E,11Z,14Z]]-; S-((5S,6R,7E,9E,11Z,14Z)-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl)-L-cysteine; LTE4, methyl ester; leukotriene E4 monomethyl ester. Grades: ≥95%. CAS No. 89461-65-4. Molecular formula: C24H39NO5S. Mole weight: 453.64. | |
| 11-trans Leukotriene C4 | 11-trans Leukotriene C4 is a C-11 double bond isomer of LTC4. Group: Biochemicals. Grades: Highly Purified. CAS No. 74841-69-3. Pack Sizes: 25ug, 50ug. Molecular Formula: C30H47N3O9S, Molecular Weight: 625.77. US Biological Life Sciences. |  Worldwide |
| 11-Trans leukotriene C4 | 11-Trans leukotriene C4 is a C-11 double bond isomer of LTC4. Synonyms: 11-trans LTC4; Leucotriene C4. Grades: ≥97%. CAS No. 74841-69-3. Molecular formula: C30H47N3O9S. Mole weight: 625.8. | |
| 11-trans Leukotriene D4 | 11-trans Leukotriene D4 is a less potent C-11 double bond isomer of LTD4. Group: Biochemicals. Grades: Highly Purified. CAS No. 79768-40-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C25H40N2O6S, Molecular Weight: 496.66. US Biological Life Sciences. | Worldwide |
| 11-trans Leukotriene E4 | 11-trans Leukotriene E4 is an equipotent C-11 double bond isomer of LTE4. Group: Biochemicals. Grades: Highly Purified. CAS No. 75715-88-7. Pack Sizes: 25ug, 50ug. Molecular Formula: C23H37NO5S, Molecular Weight: 439.61. US Biological Life Sciences. | Worldwide |
| 12-epi Leukotriene B4 | 12-epi Leukotriene B4 is a leukotriene with less affinity than LTB4 at LTB4 receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 83709-73-3. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences. | Worldwide |
| 12-Epi leukotriene B4 | 12-Epi leukotriene B4 is a leukotriene with less affinity than LTB4 at LTB4 receptors. Synonyms: 12-epi LTB4; 5S,12S-dihydroxy-6E,8Z,10E,14Z-eicosatetraenoic acid. Grades: ≥97%. CAS No. 83709-73-3. Molecular formula: C20H32O4. Mole weight: 336.5. | |
| 12-Oxoleukotriene B4 in acetonitrile | 12-oxo Leukotriene B4 in acetonitrile is a potent eicosanoid lipid mediators. Group: Biochemicals. Grades: Highly Purified. CAS No. 136696-10-1. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H30O4, Molecular Weight: 334.45. US Biological Life Sciences. | Worldwide |
| 14,15-dehydro Leukotriene B4 | 14,15-dehydro Leukotriene B4 is an LTB4 receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 114616-11-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences. | Worldwide |
| 14,15-Dehydro leukotriene B4 | 14,15-Dehydro leukotriene B4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. Synonyms: 14,15-dehydro LTB4; 5S,12R-dihydroxy-6Z,8E,10E-eicosatrien-14-ynoic acid. Grades: ≥97%. CAS No. 114616-11-4. Molecular formula: C20H30O4. Mole weight: 334.5. | |
| 14,15-Leukotriene C4 | 14,15-Leukotriene C4 is an acute inflammatory mediator. Group: Biochemicals. Grades: Highly Purified. CAS No. 75290-60-7. Pack Sizes: 25ug, 50ug. Molecular Formula: C30H47N3O9S, Molecular Weight: 625.77. US Biological Life Sciences. | Worldwide |
| 14,15-Leukotriene E4 | 14,15-Leukotriene E4 is a Leukotriene that increases vascular permeability of human endothelial cell monolayers. Group: Biochemicals. Grades: Highly Purified. CAS No. 1000852-57-2. Pack Sizes: 25ug, 50ug. Molecular Formula: C23H37NO5S, Molecular Weight: 439.61. US Biological Life Sciences. | Worldwide |
| 18-carboxy dinor Leukotriene B4 | 18-carboxy dinor Leukotriene B4 is b-oxidation metabolite of LTB4. Group: Biochemicals. Grades: Highly Purified. CAS No. 102674-12-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C18H26O6, Molecular Weight: 338.4. US Biological Life Sciences. | Worldwide |
| 20-Carboxy-Leukotriene B4 | 20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4 (LTB4; HY-107608). 20-Carboxy-Leukotriene B4 binds to the BLT1 receptor with high affinity. 20-Carboxy-Leukotriene B4 inhibits LTB4-mediated neutrophil responses (migration, degranulation, leukotriene biosynthesis) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 20-COOH LTB4. CAS No. 80434-82-8. Pack Sizes: 25 μg (272.89 μM * 250 μL in Ethanol). Product ID: HY-113483. | |
| 20-trifluoro Leukotriene B4 | 20-trifluoro Leukotriene B4 is an eicosanoid lipid mediator. Group: Biochemicals. Grades: Highly Purified. CAS No. 115178-97-7. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H29F3O4, Molecular Weight: 390.44. US Biological Life Sciences. | Worldwide |
| (-)-Leukotriene a4 methyl ester | (-)-Leukotriene a4 methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (-)-LEUKOTRIENE A4 METHYL ESTER;LEUKOTRIENE A4 METHYL ESTER;5S-TRANS-5,6-OXIDO-7E,9E,11Z,14Z-EICOSATETRAENOIC ACID, METHYL ESTER;(-)-leukotriene A4;LEUKOTRIENE A4-METHYLESTER SOLUTION (100UG/ML HEXANE/1% TRIETHYLAMINE). Product Category: Heterocyclic Organic Compound. Appearance: Oil in 2% triethylamine/hexane. CAS No. 73466-12-3. Molecular formula: C21H32O3. Mole weight: 332.48. Product ID: ACM73466123. Alfa Chemistry ISO 9001:2015 Certified. | |
| N-methyl Leukotriene C4 | N-methyl Leukotriene C4 (N-methyl LTC4) is a synthetic analog of Leukotriene C4 (LTC4) that is not readily metabolized to LTD4 and LTE4. It acts as a potent and selective CysLT2 receptor agonist. Synonyms: N-methyl LTC4. Grades: ≥97%. CAS No. 131391-65-6. Molecular formula: C31H49N3O9S. Mole weight: 639.8. | |
| 1, 1'-[Dithiobis (methylene) ]biscyclopropaneacetic Acid | 1, 1'-[Dithiobis (methylene) ]biscyclopropaneacetic Acid is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 162515-67-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 1, 1'-[Dithiobis (methylene)]biscyclopropaneacetic Acid | 1, 1'-[Dithiobis (methylene)]biscyclopropaneacetic Acid is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-[1-Carboxymethyl-cyclopropylmethyldisulfanylmethyl) cyclopropyl]acetic acid; Montelukast Disulfide Impurity; Cyclopropaneacetic acid, 1,1'-[dithiobis(methylene)]bis-; 2,2'-[Disulfanediylbis(methylene-1,1-cyclopropanediyl)]diacetic acid; 2, 2'- ( (Disulfanediylbis (methylene))bis (cyclopropane-1, 1-diyl))diacetic acid. Grades: ≥90%. CAS No. 162515-67-5. Molecular formula: C12H18O4S2. Mole weight: 290.40. | |
| 1, 1'-[Dithiobis (methylene) ]biscyclopropaneacetic Acid Methyl Ester | 1, 1'-[Dithiobis (methylene) ]biscyclopropaneacetic Acid Methyl Ester is an intermediate in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1446481-28-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1, 1'-[Dithiobis (methylene)]biscyclopropaneacetic Acid Methyl Ester | 1, 1'-[Dithiobis (methylene)]biscyclopropaneacetic Acid Methyl Ester is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: Montelukast Disulfide Dimethyl Ester; Methyl 2- (1- ( (2- ( (1-methoxycarbonylmethylcyclopropyl) methyl) disulfanyl) methyl)cyclopropyl)acetate; Cyclopropaneacetic acid, 1,1'-[dithiobis(methylene)]bis-, 1,1'-dimethyl ester; Dimethyl 2,2'-[disulfanediylbis(methylene-1,1-cyclopropanediyl)]diacetate. Grades: ≥90%. CAS No. 1446481-28-2. Molecular formula: C14H22O4S2. Mole weight: 318.45. | |
| 11-?Keto-?beta-?boswellic acid | 11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 11-Keto-β-boswellic acid. CAS No. 17019-92-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2056. | |
| 1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl ) methyl ] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1- methyl ethyl) phenyl] propyl ] thio] methyl cyclopropaneacetic Acid | 1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl ) methyl ] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1- methyl ethyl) phenyl] propyl ] thio] methyl cyclopropaneacetic Acid is derived from Montelukast Methyl Ester (M568080), which is an impurity of the antiasthmatic drug Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Used as an anti-asthmatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C41H46ClNO5S2, Molecular Weight: 732.39. US Biological Life Sciences. | Worldwide |
| 1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl) methyl] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methylcyclopropaneacetic Acid | 1- [ [ [ (1R) -1- [3- [ (2S, R) -2- [ [ (1-Carboxycyclopropyl) methyl] thio] -2- (7-chloro-2-quinolinyl) ethyl] phenyl] -3- [2- (1-hydroxy-1-methylethyl) phenyl] propyl] thio] methylcyclopropaneacetic Acid is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Molecular formula: C41H46ClNO5S2. Mole weight: 732.39. | |
| 12(S)-HHTrE | 12(S)-HHTrE is a metabolite of arachidonic acid (A3303), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides. Group: Biochemicals. Grades: Highly Purified. CAS No. 54397-84-1. Pack Sizes: 500ug, 5mg. Molecular Formula: C17H28O3, Molecular Weight: 280.399999999999. US Biological Life Sciences. | Worldwide |
| 1-(2-Tetrahydrofuroyl)piperazine | 1-(2-Tetrahydrofuroyl)piperazine. Uses: An intermediate of terazosin hydrochloride. it has also been used as a reactant for the preparation of pyrazol-3-propanoic acid derivatives as inhibitors of leukotriene biosynthesis in human neutrophils. Additional or Alternative Names: (2RS)-1-(2-Tetrahydrofuroyl)piperazine. Product Category: Solvents. CAS No. 63074-07-7. Molecular formula: C9H17N2O2. Mole weight: 185.25. IUPACName: 4-[(2S)-oxolane-2-carbonyl]piperazin-1-ium. Canonical SMILES: O=C([C@@H]1CCCO1)N1CC[NH2+]CC1. Density: 1.1±0.1 g/cm3. Product ID: ACM63074077. Alfa Chemistry ISO 9001:2015 Certified. Categories: 1-(Tetrahydro-2-furoyl)piperazine. | |
| 1,3-Bis[2-(7-chloro-2-quinolyl)vinyl]benzene | 1,3-Bis[2-(7-chloro-2-quinolyl)vinyl]benzene is an impurity of Montelukast, which is a leukotriene receptor antagonist indicated for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 1,3-Bis[(E)-2-(7-chloroquinoline-2-yl)vinyl]benzene; 2,2'-{1,3-Phenylenedi[(E)ethene-2,1-diyl]}bis(7-chloroquinoline); (E, E) -2, 2'- (1, 3-Pphenylenedi- 2, 1- ethenediyl) bis[7- chloro-quinoline]; Montelukast Impurity 18. Grades: ≥95%. CAS No. 120578-04-3. Molecular formula: C28H18Cl2N2. Mole weight: 453.36. | |
| 14,15-Epoxyeicosatrienoic Acid (±14,15-EET) | Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,?N'-?dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore. Also, it is derived from Arachidonic Acid, which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z)-13-(3-Pentyl-2-oxiranyl)-5,8,11-tridecatrienoic Acid; 14(15)-EET; 14(15)-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid; (±)14,15-EET; (±)14,15-EpETrE; (all-Z)-13-(3-Pentyloxiranyl)-5,8,11-tridecatrienoic Acid. Grades: Highly Purified. CAS No. 197508-62-6. Pack Sizes: 50ug, 100ug, 500ug. Molecular Formula: C??H??O?, Molecular Weight: 320.47. US Biological Life Sciences. | Worldwide |
| 15(S)-HPETE | 15(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A41 or reduced to 15(S)-HETE by peroxidases.2,1 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.3 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO. Uses: Scientific research. Group: Signaling pathways. CAS No. 70981-96-3. Pack Sizes: 25 μg (297.20 μM * 250 μL in Ethanol). Product ID: HY-113438. | |
| 1-(Benzo[b]thien-2-yl)ethanol | 1-(Benzo[b]thien-2-yl)ethanol is an intermediate used to prepare amino sugar and related sugar derivatives of indolopyrrolocarbazole s as antitumors. It is also an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Zileuton is used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 51868-95-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C10H10OS, Molecular Weight: 178.25. US Biological Life Sciences. | Worldwide |
| 1- ( (Benzyloxy) methyl ) cyclopropane carbaldehyde | 1- ( (Benzyloxy) methyl ) cyclopropane carbaldehyde is an protected intermediate used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 1- ( (Benzyloxy) methyl) cyclopropanecarbaldehyde | 1- ( (Benzyloxy) methyl) cyclopropanecarbaldehyde is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: Cyclopropanecarboxaldehyde, 1-[(phenylmethoxy)methyl]-; 1-((Benzyloxy)methyl)cyclopropane-1-carbaldehyde. CAS No. 288401-39-8. Molecular formula: C12H14O2. Mole weight: 190.24. | |
| [1- [ (Benzyloxy) methyl] cyclopropyl] methanol | [1- [ (Benzyloxy) methyl] cyclopropyl] methanol is an protected intermediate used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Alternative Names: 1- [ (Phenylmethoxy) methyl] cyclopropanemethanol. Grades: Highly Purified. CAS No. 177200-76-9. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| [1-[ (Benzyloxy) methyl]cyclopropyl]methanol | [1-[ (Benzyloxy) methyl]cyclopropyl]methanol is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-[ (Phenylmethoxy) methyl]cyclopropanemethanol. Grades: ≥95%. CAS No. 177200-76-9. Molecular formula: C12H16O2. Mole weight: 192.25. | |
| [1- [Bis (Benzyloxy) methyl] cyclopropyl] methanol | [1- [Bis (Benzyloxy) methyl] cyclopropyl] methanol is an protected intermediate used in the synthesis of Montelukast (M568000), a selective leukotriene D4-receptor antagonist used as an antiasthmatic agent. Group: Biochemicals. Alternative Names: ( ( (Cyclopropane-1, 1-diylbis (methylene))bis (oxy))bis (methylene))dibenzene. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| (1- (Cyanomethyl) cyclopropyl) methyl Methanesulfonate | (1- (Cyanomethyl) cyclopropyl) methyl Methanesulfonate is an impurity of Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 152922-86-6. Pack Sizes: 100mg, 1g. Molecular Formula: C7H11NO3S, Molecular Weight: 189.23. US Biological Life Sciences. | Worldwide |
| (1-(Cyanomethyl)cyclopropyl)methyl Methanesulfonate | (1-(Cyanomethyl)cyclopropyl)methyl Methanesulfonate is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: 1-[[ (Methylsulfonyl) oxy]methyl]cyclopropaneacetonitrile. CAS No. 152922-86-6. Molecular formula: C7H11NO3S. Mole weight: 189.23. | |
| 1-Cyclopentylethanone-d4 | 1-Cyclopentylethanone-d4, is the labeled analogue of 1-Cyclopentylethanone (C988475), that can be used in the preparation of small molecule inhibitors of rifampicin resistant Staphylococcus aureus. An antibacterial agent. Also used in the synthesis of non-quinoline leukotriene D4 (LTD4) receptor antagonists. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C7H8D4O, Molecular Weight: 116.19. US Biological Life Sciences. | Worldwide |
| 1- (Mercapto methyl ) cyclopropane acetonitrile | 1- (Mercapto methyl ) cyclopropane acetonitrile is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist. Also used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 866923-64-0. Pack Sizes: 100mg, 1g. Molecular Formula: C6H9NS, Molecular Weight: 127.21. US Biological Life Sciences. | Worldwide |
| 1-?(Tetrahydro-?2-?furoyl)?-?piperazine | 1-?(Tetrahydro-?2-?furoyl)?-?piperazine (Terazosin EP Impurity N) has been used as a reactant for the preparation of pyrazol-3-propanoic acid derivatives as inhibitors of leukotriene biosynthesis in human neutrophils. Group: Biochemicals. Grades: Highly Purified. CAS No. 63074-07-7. Pack Sizes: 1g, 2.5g. Molecular Formula: C9H16N2O2. US Biological Life Sciences. | Worldwide |
| 20-COOH-LTB4 | 20-COOH-LTB4 is a leukotriene B4 metabolite and substrate for β-oxidation pathways. Group: Biochemicals. Grades: Highly Purified. CAS No. 80434-82-8. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H30O6, Molecular Weight: 366.45. US Biological Life Sciences. | Worldwide |
| [2- (1, 3-Dioxan-2-yl) ethyl] triphenylphosphonium Bromide | [2- (1, 3-Dioxan-2-yl) ethyl] triphenylphosphonium Bromide is used in synthesis of leukotrienes. Group: Biochemicals. Grades: Highly Purified. CAS No. 69891-92-5. Pack Sizes: 500mg, 1g. Molecular Formula: C24H26O2P+; Br-, Molecular Weight: 377.44799. US Biological Life Sciences. | Worldwide |
| 21(R)-Hydroxy Montelukast | 21(R)-Hydroxy Montelukast is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: [R-[R*, R*- (E) ]]-1-[[[1-[3-[2- (7-Chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxy-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid; Montelukast M5b; {1-[ ({ (1R, 3R) -1-{3-[ (E) -2- (7-Chloro-2-quinolinyl) vinyl]phenyl}-3-hydroxy-3-[2- (2-hydroxy-2-propanyl) phenyl]propyl}sulfanyl) methyl]cyclopropyl}acetic acid; Cyclopropaneacetic acid, 1-[[[ (1R, 3R) -1-[3-[ (E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxy-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-. Grades: 95%. CAS No. 184763-26-6. Molecular formula: C35H36ClNO4S. Mole weight: 602.18. | |
| 21(S)-Hydroxy Montelukast | 21(S)-Hydroxy Montelukast is a metabolite of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: [R-[R*, S*- (E) ]]-1-[[[1-[3-[2- (7-Chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxy-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid; Montelukast M5a; {1-[ ({ (1R, 3S) -1-{3-[ (E) -2- (7-Chloro-2-quinolinyl) vinyl]phenyl}-3-hydroxy-3-[2- (2-hydroxy-2-propanyl) phenyl]propyl}sulfanyl) methyl]cyclopropyl}acetic acid; Cyclopropaneacetic acid, 1-[[[ (1R, 3S) -1-[3-[ (E) -2- (7-chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxy-3-[2- (1-hydroxy-1-methylethyl) phenyl]propyl]thio]methyl]-. Grades: 95%. CAS No. 184763-29-9. Molecular formula: C35H36ClNO4S. Mole weight: 602.18. | |
| 2-[2-[ (3S)-3-[3-[ (E)-2- (7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[ (methanesulfonyl)oxy]propyl]phenyl]-2-propanol | 2-[2-[ (3S)-3-[3-[ (E)-2- (7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[ (methanesulfonyl)oxy]propyl]phenyl]-2-propanol is an intermediate of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: (αS)-α-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)benzenepropanol α-Methanesulfonate; Montelukast Impurity 35; Benzenepropanol, α-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methylethyl)-, α-methanesulfonate, (αS)-; 2-[2-[ (3S)-3-[3-[ (E)-2- (7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[ (methanesulfonyl)oxy]propyl]phenyl]-2-propanol. Grades: ≥95%. CAS No. 807638-71-7. Molecular formula: C30H30ClNO4S. Mole weight: 536.08. | |
| 2,2-Dimethoxy-d6 Montelukast | 2,2-Dimethoxy Montelukast is an intermediate in the synthesis of Methoxy-d3 Montelukast (M264527), a labeled impurity of Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C37H34D6ClNO3S, Molecular Weight: 620.27. US Biological Life Sciences. | Worldwide |
| 2, 2'- ( (Disulfanediylbis (methylene))bis (cyclopropane-1, 1-diyl))bis (2-hydroxyacetic Acid) Diethyl Ester | 2, 2'- ( (Disulfanediylbis (methylene))bis (cyclopropane-1, 1-diyl))bis (2-hydroxyacetic Acid) Diethyl Ester is an impurity of Montelukast, which is a leukotriene D4-receptor antagonist used in the treatment of allergies and asthma. Synonyms: Diethyl 2, 2'- ( (Disulfanediylbis (methylene))bis (cyclopropane-1, 1-diyl))bis (2-hydroxyacetate). Molecular formula: C16H26O6S2. Mole weight: 378.50. | |
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