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3-(1H-Tetrazol-5-yl)piperidine is an intermediate used to prepare amino-substituted arylthiophenyl oxazoles, thiazoles, pyridines and pyrimidines as isosteres of trans-cinnamides and potent antagonists of LFA-1/ICAM-1 binding. Group: Biochemicals. Grades: Highly Purified. CAS No. 112626-96-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C6H11N5, Molecular Weight: 153.19. US Biological Life Sciences.
3-Bromo-D-phenylalanine can be used in the synthesis of 3-(Methylsulfonyl)-D-phenylalanine Hydrochloride, which has been found to be a potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for treating dry eye. Synonyms: H-D-Phe(3-Br)-OH. Grade: ≥ 98% (HPLC). CAS No. 99295-78-0. Molecular formula: C9H10BrNO2. Mole weight: 244.09.
Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 77095-51-3. Pack Sizes: 250mg, 1g. Molecular Formula: C9H6O3, Molecular Weight: 162.139999999999. US Biological Life Sciences.
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Diethanolamine
Diethanolamine similar to triethanolamine (T775580) is used as a surfactant. It also has the potential to be a corrosion inhibitor by means of chemisorption. Group: Biochemicals. Alternative Names: 2,2'-Iminobis-Ethanol; 2,2'-Iminodi-Ethanol; 2,2'-Dihydroxydiethylamine; 2,2'-Iminobis[ethanol]; 2,2'-Iminodi-1-ethanol; 2,2'-Iminodiethanol; 2-[ (2-Hydroxyethyl) amino]ethanol; Bis(2-hydroxyethyl)amine; Bis (hydroxyethyl)amine; DEA; DEA 80; DEAO-LF; Dabco DEOA-LF; Di(2-hydroxyethyl)amine; Di( β-hydroxyethyl)amine; Diethanolamine; Diethanolamine 80; Diolamine; Iminodiethanol; N,N-Bis(2-hydroxyethyl)amine; N,N-Di(2-hydroxyethyl)amine; N,N-Diethanolamine; NSC 4959; Niax DEOA-LF. Grades: Highly Purified. CAS No. 111-42-2. Pack Sizes: 5g. US Biological Life Sciences.
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Lifitegrast
Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC 50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAR 1118; SHP-606. CAS No. 1025967-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19344.
Lifitegrast sodium
Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC 50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAR 1118 sodium; SHP-606 sodium. CAS No. 1119276-80-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19344A.
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys
N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys is a formyl peptide receptor (FPR) agonist. Synonyms: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH; F-chemotactic peptide; N-Formyl-NLE-LF-NLE-YK; N-formyl-L-norleucyl-L-leucyl-L-phenylalanyl-L-norleucyl-L-tyrosyl-L-lysine; N-Formyl hexapeptide; (3S,6S,9S,12S,15S,18S)-18-(4-Aminobutyl)-9-benzyl-3,12-dibutyl-15-(4-hydroxybenzyl)-6-isobutyl-1,4,7,10,13,16-hexaoxo-2,5,8,11,14,17-hexaazanonadecan-19-oic acid. Grade: ≥95% by HPLC. CAS No. 71901-21-8. Molecular formula: C43H65N7O9. Mole weight: 824.02.