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| Product | Description | |
|---|---|---|
| Licochalcone A | Licochalcone A. Group: Biochemicals. Grades: Plant Grade. CAS No. 58749-22-7. Pack Sizes: 20mg. Molecular Formula: C21H22O4, Molecular Weight: 338.4. US Biological Life Sciences. |  Worldwide |
| Licochalcone A | Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. It is a potent membrane-active agent that transforms normal erythrocytes into echinocytes. It exhibits potent antimalarial activity and might be developed into a new antimalarial drug. It had anti-tumor activity in all cell lines tested and enhanced the effect of paclitaxel and vinblastine chemotherapy. Synonyms: 4,4'-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone; 7-Dimethoxycoumarin; 3-Dimethylallyl-4,4'-dihydroxy-6-methoxychalcone; (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one; (2E)-3-[5-(1,1-Dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-; 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (E)-. Grade: >98%. CAS No. 58749-22-7. Molecular formula: C21H22O4. Mole weight: 338.40. |  |
| Licochalcone A | Licochalcone A (LCA), a flavonoid isolated, presents obvious anti-cancer effects, displays broad-spectrum inhibition against UDP-glucuronosyltransferases (UGTs) [1]. Licochalcone A (LCA) exhibits strong inhibitory effects against UGT1A1, 1A3, 1A4, 1A6, 1A7, 1A9, and 2B7 (both IC 50 and K i values lower than 5 μM) [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Licochalcone-A. CAS No. 58749-22-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0372. |  |
| Licochalcone B | Licochalcone B. Group: Biochemicals. CAS No. 58749-23-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Licochalcone B | Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid ? (42) self-aggregation (IC50=2.16 ?M) and disaggregate pre-formed A?42 fibrils, reduce metal-induced A?42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-?B p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7?NLRP3 interaction[1][2][3][4]. Uses: Scientific research. Group: Natural products. CAS No. 58749-23-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0373. | |
| Licochalcone B | Licochalcone B is extracted from the roots of Glycyrrhiza glabra L. It inhibits the adhesion,invasion and metastasis of human malignant bladder cancer T24 cells. It could significantly reduce the LPS-induced production of NO, TNFalpha and MCP-1. Synonyms: (2E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (E)-; (E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 3,4,4'-Trihydroxy-2-methoxy-trans-chalcone; 3,4,4'-Trihydroxy-2-Methoxychalcone. Grade: >98%. CAS No. 58749-23-8. Molecular formula: C16H14O5. Mole weight: 286.28. | |
| Licochalcone C | Licochalcone C could inhibit α-glucosidase , with IC 50 s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Uses: Scientific research. Group: Natural products. CAS No. 144506-14-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0374. | |
| Licochalcone D | Licochalcone D, a flavonoid compound mainly existing in the root of Glycyrrhiza uralensis, is a potent and orally active inhibitor of NF-kappaB (NF-?B) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 144506-15-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N4187. | |
| Licochalcone E | Licochalcone E, a flavonoid compound isolated from Glycyrrhiza uralensis, inhibits NF-?B and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation[1]. Uses: Scientific research. Group: Natural products. CAS No. 864232-34-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4182. | |
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