Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| LL Z1640-2 | LL Z1640-2 is a macrolide antibiotic produced by the strain of Deuteromyces sp. It is an irreversible and highly selective TAK 1 inhibitor and a member of the MAPKKK family that activates JNK/p38 and NF-κB pro-inflammatory signaling pathways. It effectively prevents inflammation in animal models. LL Z1640-2 is a covalent inhibitor that acts against the several protein kinases (e.g. ERK2 and TAK1) which possess a free cysteine at the gatekeeper-2 position. Synonyms: C292; L 783278; Antibiotic LL Z1640-2; (3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; (-)-LL-Z 1640-2; (5Z)-7-Oxozeaenol; (Z)-7-Oxozeaenol; C 292; F 152; f 152 A1; FR 148083; LL-Z 1640-2. Grades: >99% by HPLC. CAS No. 253863-19-3. Molecular formula: C19H22O7. Mole weight: 362.37. |  |
| Antibiotic LL Z1640-2 (Antibiotic C292, Antibiotic L 783278) | Antibiotic LL Z1640-2 a cis-enone resorcylic acid lactone first reported in 1978 and later rediscovered as an irreversible and highly selective TAK 1 inhibitor. TAK1 is a MAPKKK involved in the p38 signalling cascade for pro-inflammation signals such as cytokines. LL Z1640-2 effectively prevents inflammation in an animal models. Group: Biochemicals. Alternative Names: Antibiotic C292, Antibiotic L 783278. Grades: Highly Purified. CAS No. 66018-38-0. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Antibiotic LL Z1640-4 (Zeaenol) | Antibiotic LL Z1640-4 is a cis-enol resorcylic acid lactone first reported in 1978 exhibiting both antiviral and antiprotozoan activity. More recently, antibiotic LL Z1640-2 containing the essential cis-enone system that selectively inhibits TAK 1 has gained literature focus. With its inactive cis-enol, Antibiotic LL Z1640-4 is an ideal negative control to help dissect the selectivity of the MAP kinases. Group: Biochemicals. Alternative Names: Zeaenol. Grades: Highly Purified. CAS No. 66018-41-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
