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Lomefloxacin is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms, which is commonly used to treat bacterial infections, including bronchitis and urinary tract infections. It is used as a pre-operative prophylactic to prevent urinary tract infection caused by S. pneumoniae, H. influenzae, S. aureus, P. aeruginosa, E. cloacae, P. mirabilis, C. civersus, S. asprphyticus, E. coli, and K. pneumoniae. It is used to induce genomic instability in mice1 and modification of the kinetics of growth of Gram-negative bacteria. It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. Uses: Anti-bacterial agents. Synonyms: Maxaquin; SC47111A. Grades: >98%. CAS No. 98079-51-7. Molecular formula: C17H19F2N3O3. Mole weight: 351.35.
Lomefloxacin·HCl 99+% (HPLC)
Lomefloxacin·HCl 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Lomefloxacin hydrochloride
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C17H19F2N3O3 · HCl. CAS No. 98079-51-7. Prepack ID 39370200-1g. Molecular Weight 387.81. See USA prepack pricing.
Lomefloxacin hydrochloride
Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic , with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC47111A hydrochloride. CAS No. 98079-52-8. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0455.
Lomefloxacin, Hydrochloride
Fluorinated quinolone antibacterial. DNA gyrase antagonist. Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic. Lomefloxacin is an orally bioavailable, broad-spectrum fluoroquinolone antibiotic.1 In vitro, it inhibits growth of N. gonorrhoeae, E. coli, K. pneumoniae, P. vulgaris, S. epidermidis, and M. morganii (MIC90s = 0.1, 0.39, 0.39, 0.39, 0.39, and 0.78ug/ml, respectively). It also inhibits growth of S. aureus and methicillin-resistant S. aureus (MRSA; MIC90 = 3.13ug/ml for both) and of H. influenzae and ampicillin-resistant H. influenzae (MIC90 = 0.1ug/ml for both). In vivo, lomefloxacin inhibits the growth of P. mirabilis, E. coli, K. pneumoniae, and S. aureus (ED50s = 1.39, 1.45, 1.78, and 6.66mg/kg, respectively) in mouse models of systemic infection. It inhibits bacterial DNA gyrase, thereby inhibiting DNA synthesis and bacterial growth.2 Formulations containing lomefloxacin have been used in the treatment of bronchitis and urinary tr Group: Biochemicals. Alternative Names: 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride; Alkaflox; Bareon; Chimono; Lomebact; Lomef 400; Lomflox; Lomitas; Lomoxin; Maxaquin; Mazaquin; NY 198; Orchacin; SC 47111; Uniquin. Grades: Highly Purified. CAS No. 98079-52-8. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C17H20ClF2N3O3, Molecular Weight: 387.81. US Biological Life Sciences.
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2,3,4-Trichloronitrobenzene
2,3,4-Trichloronitrobenzene is a useful synthetic intermediate that is mainly used as the starting material in the synthesis of third generation quinolone antibacterial drugs, such as Lomefloxacin (L469415, HCl) and Ofloxacin (O245750). 2,3,4-Trichloronitrobenzene is also used as the starting material in the synthesis of Aclonifen (A190200); a compound used as a pesticide and herbicide. Group: Biochemicals. Grades: Highly Purified. CAS No. 17700-09-3. Pack Sizes: 5g, 10g. Molecular Formula: C6H2Cl3NO2, Molecular Weight: 226.44. US Biological Life Sciences.
Worldwide
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