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| Product | Description | |
|---|---|---|
| Lonafarnib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. |  |
| Lonafarnib | Lonafarnib. Group: Biochemicals. Alternative Names: 4-[2-[4-[(11R)-3, 10-Dibromo-8-chloro-6, 11-dihydro-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide; Sarasar; Sch 66336. Grades: Highly Purified. CAS No. 193275-84-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H31Br2ClN4O2. US Biological Life Sciences. |  Worldwide |
| Lonafarnib | Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras , K-ras and N-ras with IC 50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch66336. CAS No. 193275-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15136. |  |
| Lonafarnib-[d9] | Lonafarnib-[d9] is an isotope laballed analog of Lonafarnib. Lonafarnib is a farnesyltransferase inhibitor (FTI) used for the treatment of progeria. Synonyms: Lonafarnib D9. Grade: 95% by HPLC; 95% atom D. CAS No. 1197367-02-4. Molecular formula: C27H22D9Br2ClN4O2. Mole weight: 647.88. |  |
| 3, 10-Dibromo-8-chloro-6, 11-dihydro-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine | 3, 10-Dibromo-8-chloro-6, 11-dihydro-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine is used in the synthetic preparation of lonafarnib, a potential anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 272107-22-9. Pack Sizes: 500mg, 1g. Molecular Formula: C14H10Br2ClN, Molecular Weight: 387.5. US Biological Life Sciences. | Worldwide |
| AZD-3409 | AZD-3409 is a potent prenyl transferase inhibitor. AZD-3409 showed higher potency than lonafarnib. AZD3409 inhibits farnesylation to a higher extent than geranylgeranylation. AZD3409 might be active in gefitinib-resistant breast carcinoma. Synonyms: AZD-3409; AZD 3409; AZD3409. Grade: 98%. CAS No. 345915-10-8. Molecular formula: C34H41FN4O4S2. Mole weight: 652.844. | |
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