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Lotaustralin, a naturally occurring compound discovered across diverse plant species, manifests noteworthy anti-inflammatory and analgesic attributes through its adept regulation of pivotal biochemical pathways. Extensive investigations have illuminated Lotaustralin's therapeutic potential in combatting an array of ailments, encompassing cancer and neurodegenerative disorders. Synonyms: 2-(b-D-Glucopyranosyloxy)-2-methylbutyronitrile. CAS No. 534-67-8. Molecular formula: C11H19NO6. Mole weight: 261.27.
Lotaustralin
Lotaustralin is a cyanogenic glucoside isolated from Manihot esculenta [1]. Uses: Scientific research. Group: Natural products. CAS No. 1973415-50-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N5079.
Lotaustralin (Mixture of Diastereomers)
A bioactive constituent of Chinese natural medicines. Synonyms: 2-(β-D-Glucopyranosyloxy)-2-methylbutyronitrile; 2-(β-D-Glucopyranosyloxy)-2-methyl-butanenitrile. Molecular formula: C11H19NO6. Mole weight: 261.27.
Lotaustralin Tetraacetate
Lotaustralin Tetraacetate is an intermediate in the synthesis of (R)-Lotaustralin, which is a bioactive constituent of Chinese natural medicines. Synonyms: Lotaustralin Tetraacetate (Ester). CAS No. 27749-93-5. Molecular formula: C19H27NO10. Mole weight: 429.42.
(2RS)-Lotaustralin
(2RS)-Lotaustralin. Group: Biochemicals. CAS No. 1973415-50-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
(2RS)-Lotaustralin
(2RS)-Lotaustralin is found in the roots of Rhodiola rosea L. Grades: >98%. CAS No. 1973415-50-7. Molecular formula: C11H19NO6. Mole weight: 261.27.
Epilotaustralin Tetraacetate
Epilotaustralin Tetraacetate is an intermediate in the synthesis of (R)-Lotaustralin, which is a bioactive constituent of Chinese natural medicines. Synonyms: Epilotaustralin Tetraacetate (Ester). CAS No. 27749-92-4. Molecular formula: C19H27NO10. Mole weight: 429.42.
rac-Lotaustralin
rac-Lotaustralin is a prodigious and potent compound used for studying the menacing forces of breast and lung carcinomas. Synonyms: 2-(b-D-Glucopyranosyloxy)-2-methylbutyronitrile. Molecular formula: C11H19NO6. Mole weight: 261.27.
aliphatic (R)-hydroxynitrile lyase
The enzyme contains Zn2+. The enzyme catalyses the stereoselective synthesis of aliphatic (R)-cyanohydrins. No activity towards mandelonitrile and 4-hydroxymandelonitrile. Natural substrates for the (R)-oxynitrilase from Linum usitatissimum are acetone and butan-2-one, which are the building blocks of the cyanogen glycosides in Linum, linamarin and lotaustralin, or linustatin and neolinustatin, respectively. Group: Enzymes. Synonyms: (R)-HNL; (R)-oxynitrilase; (R)-hydroxynitrile lyase; LuHNL. Enzyme Commission Number: EC 4.1.2.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4882; aliphatic (R)-hydroxynitrile lyase; EC 4.1.2.46; (R)-HNL; (R)-oxynitrilase; (R)-hydroxynitrile lyase; LuHNL. Cat No: EXWM-4882.
isoleucine N-monooxygenase
A heme-thiolate protein (P-450). This enzyme catalyses two successive N-hydroxylations of L-isoleucine, the first committed steps in the biosynthesis of the cyanogenic glucoside lotaustralin in the plant Lotus japonicus. The product of the two hydroxylations, N,N-dihydroxy-L-isoleucine, is extremely labile and dehydrates spontaneously. The dehydrated product is then subject to a decarboxylation that produces the oxime. It is still not known whether the decarboxylation is spontaneous or catalysed by the enzyme. The product, (E)-2-methylbutanal oxime, undergoes a spontaneous isomerization to the (Z) form. The enzyme can also accept L-valine as substrate, with a lower activity. It is different from EC 1.14.13.118 (valine N-monooxygenase), which prefers L-valine. Group: Enzymes. Synonyms: CYP79D3; CYP79D4. Enzyme Commission Number: EC 1.14.13.117. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0717; isoleucine N-monooxygenase; EC 1.14.13.117; CYP79D3; CYP79D4. Cat No: EXWM-0717.
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