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| Product | Description | |
|---|---|---|
| Lubiprostone | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral molecules. Alternative Names: (11?)-16,16-difluoro-11-hydroxy-9,15-dioxo-Prostan-1-oic acid, Lubiprostone, Ru 0211. |  |
| Lubiprostone | Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation. Group: Biochemicals. Alternative Names: (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid; Ru 0211. Grades: Highly Purified. CAS No. 136790-76-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. US Biological Life Sciences. |  Worldwide |
| Lubiprostone | Lubiprostone (SPI-0211; RU0211) increases intestinal fluid secretion through generation of CIC-2 / CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU-0211; SPI-0211. CAS No. 136790-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0679. |  |
| Lubiprostone-[d7] | Lubiprostone-[d7] is the labelled analogue of Lubiprostone, which is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of bloating and abdominal discomfort. Synonyms: Lubiprostone D7; (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid-d7. Grade: 95% by HPLC; 95% atom D. CAS No. 1217675-13-2. Molecular formula: C20H25D7F2O5. Mole weight: 397.51. |  |
| 11-O-Tetrahydropyranyl-15-O-tert-butyldimethylsilyl-lubiprostone-d7 Phenylmethyl Ester | Intermediate in the synthesis of Hydroxy Lubiprostone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 11-O-Tetrahydropyranyl-15-O-tert-butyldimethylsilyl-lubiprostone Phenylmethyl Ester | Intermediate in the synthesis of Hydroxy Lubiprostone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 15-Hydroxy Lubiprostone | 15-Hydroxy Lubiprostone is a synthetic derivative of prostaglandin E1 used in the biomedical industry. It acts as a local intestinal chloride channel activator and is employed in the research of chronic idiopathic constipation and irritable bowel syndrome with constipation. Synonyms: 9-oxo-11α,15S-dihydroxy-16,16-difluoro-prostan-1-oic acid. Grade: > 95%. CAS No. 475992-30-4. Molecular formula: C20H34F2O5. Mole weight: 392.5. | |
| 15-Hydroxy lubiprostone-d4 | 15-Hydroxy lubiprostone-d4 is a labelled impurity of lubiprostone. Lubiprostone is a medication indicated for the treatment of certain types of constipation. Synonyms: 7-[2-(4,4-difluoro-3-hydroxyoctyl)-3-hydroxy-5- oxocyclopentyl](2,2,4,4-D4)heptanoic acid. Grade: > 95%. Molecular formula: C20H30F2O5D4. Mole weight: 396.51. | |
| 15-Hydroxy Lubiprostone-[d7] | 15-Hydroxy Lubiprostone-[d7], is the labelled analogue of 15-Hydroxy Lubiprostone, which is an impurity of Lubiprostone. Lubiprostone is a medication used in the management of chronic idiopathic constipation. Synonyms: (11α)-16,16-Difluoro-11,15-dihydroxy-9-oxoprostan-1-oic Acid-d7; 15-Hydroxy Lubiprostone D7. Grade: 95% (CP); 95% atom D. CAS No. 1217511-55-1. Molecular formula: C20H27D7F2O5. Mole weight: 399.53. | |
| 15-Hydroxy Lubiprostone Phenylmethyl Ester | Protected Hydroxy Lubiprostone , a halogenated bioactive lipid. Group: Biochemicals. Alternative Names: (11α)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| O-Tetrahydropyranyl lubiprostone | O-Tetrahydropyranyl lubiprostone. Group: Biochemicals. Alternative Names: (11a)-16,16-Difluoro-9,15-dioxo-11-[(tetrahydro-2H-pyran-2-yl)oxy]prostan-1-oic acid. Grades: Highly Purified. CAS No. 876068-08-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C25H40F2O6. US Biological Life Sciences. | Worldwide |
| O-Tetrahydropyranyl Lubiprostone-d7 | Protected precursor to labeled Lubiprostone. Group: Biochemicals. Alternative Names: (11α)-16,16-Difluoro-9,15-dioxo-11-[(tetrahydro-2H-pyran-2-yl)oxy]prostan-1-oic Acid-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (5Z) -7-[ (5-Acetyloxy-2- (4-difluoro-3-octen-1-one) -3-tetrahydropyranyloxy) cyclopentyl]-5-heptenoic Acid Benzyl Ester | Intermediate in the preparation of Lubiprostone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (5Z) -7-[ (5-Acetyloxy-2-formyl-3-tetrahydropyranyloxy) cyclopentyl]-5-heptenoic Acid Benzyl Ester | Intermediate in the preparation of Lubiprostone. Group: Biochemicals. Alternative Names: 7-[5-(Benzoyloxy)-2-formyl-3-[(tetrahydro-2H-pyran-2-yl)oxy]cyclopentyl]-5-heptenoic Acid Benzyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 7-[3,5-Hydroxy-2-(3-O-tertbutyldimethylsilyl-4-difluoro)octane] Heptanoic Acid | Intermediate in the synthesis of Hydroxy Lubiprostone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (±)-Corey lactone diol | (±)-Corey lactone diol is an impurity of lubiprostone, a bicyclic fatty acid metabolite analog of Prostaglandin E1. Synonyms: (3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one. Grade: >95%. CAS No. 54423-47-1. Molecular formula: C8H12O4. Mole weight: 172.18. | |
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