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| Product | Description | |
|---|---|---|
| Lubiprostone | Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation. Group: Biochemicals. Alternative Names: (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid; Ru 0211. Grades: Highly Purified. CAS No. 136790-76-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. US Biological Life Sciences. |  Worldwide |
| Lubiprostone | Lubiprostone is a bicyclic fatty acid metabolite of Prostaglandin E1. It activates ClC-2 and CFTR chloride channels in the gastrointestinal tract, increasing intestinal fluid secretion. It is used in the management of idiopathic chronic constipation, and irritable bowel syndrome with constipation. Synonyms: Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-; (11α)-16,16-Difluoro-11-hydroxy-9,15-dioxoprostan-1-oic acid; RU 0211. Grades: ≥98%. CAS No. 136790-76-6. Molecular formula: C20H32F2O5. Mole weight: 390.47. |  |
| Lubiprostone | Lubiprostone (SPI-0211; RU0211) increases intestinal fluid secretion through generation of CIC-2 / CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU-0211; SPI-0211. CAS No. 136790-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0679. |  |
| Lubiprostone impurity 1 | Lubiprostone impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2743427-14-5. Molecular Formula: C20H32F2O5. Mole Weight: 390.47. Catalog: APB2743427145. |  |
| Lubiprostone related compound 1 | Grades: > 95%. Molecular formula: C20H32F2O5. Mole weight: 390.47. | |
| Lubiprostone related compound 2 | Grades: > 95%. Molecular formula: C20H32F2O5. Mole weight: 390.47. | |
| Lubiprostone Related Compound 3 | Grades: > 95%. CAS No. 1263283-38-0. Molecular formula: C20H32F2O5. Mole weight: 390.47. | |
| Lubiprostone Related Compound 4 | Grades: > 95%. Molecular formula: C13H18O5. Mole weight: 254.29. | |
| Lubiprostone Related Compound 5 | Grades: > 95%. Molecular formula: C13H20O5. Mole weight: 256.30. | |
| Lubiprostone Related Compound 7 | Grades: > 95%. Molecular formula: C20H32F2O5. Mole weight: 390.47. | |
| Lubiprostone Related Compound 8 | Grades: > 95%. Molecular formula: C20H32F2O5. Mole weight: 390.47. | |
| 11-O-Tetrahydropyranyl-15-O-tert-butyldimethylsilyl-lubiprostone-d7 Phenylmethyl Ester | Intermediate in the synthesis of Hydroxy Lubiprostone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 11-O-Tetrahydropyranyl-15-O-tert-butyldimethylsilyl-lubiprostone Phenylmethyl Ester | Intermediate in the synthesis of Hydroxy Lubiprostone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 15-Hydroxy Lubiprostone | Synonyms: 9-oxo-11α,15S-dihydroxy-16,16-difluoro-prostan-1-oic acid. Grades: > 95%. CAS No. 475992-30-4. Molecular formula: C20H34F2O5. Mole weight: 392.5. | |
| 15-Hydroxy Lubiprostone Phenylmethyl Ester | Protected Hydroxy Lubiprostone , a halogenated bioactive lipid. Group: Biochemicals. Alternative Names: (11α)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| O-Tetrahydropyranyl lubiprostone | O-Tetrahydropyranyl lubiprostone. Group: Biochemicals. Alternative Names: (11a)-16,16-Difluoro-9,15-dioxo-11-[(tetrahydro-2H-pyran-2-yl)oxy]prostan-1-oic acid. Grades: Highly Purified. CAS No. 876068-08-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C25H40F2O6. US Biological Life Sciences. | Worldwide |
| O-Tetrahydropyranyl Lubiprostone-d7 | Protected precursor to labeled Lubiprostone. Group: Biochemicals. Alternative Names: (11α)-16,16-Difluoro-9,15-dioxo-11-[(tetrahydro-2H-pyran-2-yl)oxy]prostan-1-oic Acid-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (5Z) -7-[ (5-Acetyloxy-2- (4-difluoro-3-octen-1-one) -3-tetrahydropyranyloxy) cyclopentyl]-5-heptenoic Acid Benzyl Ester | Intermediate in the preparation of Lubiprostone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (5Z) -7-[ (5-Acetyloxy-2-formyl-3-tetrahydropyranyloxy) cyclopentyl]-5-heptenoic Acid Benzyl Ester | Intermediate in the preparation of Lubiprostone. Group: Biochemicals. Alternative Names: 7-[5-(Benzoyloxy)-2-formyl-3-[(tetrahydro-2H-pyran-2-yl)oxy]cyclopentyl]-5-heptenoic Acid Benzyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 7-[3,5-Hydroxy-2-(3-O-tertbutyldimethylsilyl-4-difluoro)octane] Heptanoic Acid | Intermediate in the synthesis of Hydroxy Lubiprostone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (±)-Corey lactone diol | (±)-Corey lactone diol is an impurity of lubiprostone, a bicyclic fatty acid metabolite analog of Prostaglandin E1. Synonyms: (3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one. Grades: >95%. CAS No. 54423-47-1. Molecular formula: C8H12O4. Mole weight: 172.18. | |
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