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Lucitanib Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR , potently and selectively inhibits VEGFR1 , VEGFR2 , VEGFR3 , FGFR1 and FGFR2 with IC 50 s of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-3810. CAS No. 1058137-23-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15391. MedChemExpress MCE
E 3810 dihydrochloride E 3810 dihydrochloride is a dual VEGFR/FGFR tyrosine kinase inhibitor. It suppresses the tumor angiogenesis and tumor cell proliferation via inhibiting VEGFR1, -2, and -3 and FGFR-1 and -2 kinases in the nanomolar range. Uses: Antitumor agent. Synonyms: E 3810 dihydrochloride; E3810 dihydrochloride; E-3810 dihydrochloride; Lucitanib dihydrochloride; 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-methylnaphthalene-1-carboxamide dihydrochloride. Grade: 99%. CAS No. 2108875-91-6. Molecular formula: C26H25N3O4.2HCl. Mole weight: 516.42. BOC Sciences 7

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