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| Product | Description | |
|---|---|---|
| Lumazine | Lumazine is a fluorescent pteridine. Synonyms: 2,4-Pteridinediol; 2,4(1H,3H)-Pteridinedione. Grades: >95% by HPLC. CAS No. 487-21-8. Molecular formula: C6H4N4O2. Mole weight: 164.12. |  |
| 6,7-dimethyl-8-ribityllumazine synthase | Involved in riboflavin biosynthesis. Group: Enzymes. Synonyms: lumazine synthase; 6,7-dimethyl-8-ribityllumazine synthase 2; 6,7-dimethyl-8-ribityllumazine synthase 1; lumazine synthase 2; lumazine synthase 1; type I lumazine synthase; type II lumazine synthase; RIB4; MJ0303; RibH; Pbls; MbtLS; RibH1 protein; RibH2 protein; RibH1; RibH2. Enzyme Commission Number: EC 2.5.1.78. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2816; 6,7-dimethyl-8-ribityllumazine synthase; EC 2.5.1.78; lumazine synthase; 6,7-dimethyl-8-ribityllumazine synthase 2; 6,7-dimethyl-8-ribityllumazine synthase 1; lumazine synthase 2; lumazine synthase 1; type I lumazine synthase; type II lumazine synthase; RIB4; MJ0303; RibH; Pbls; MbtLS; RibH1 protein; RibH2 protein; RibH1; RibH2. Cat No: EXWM-2816. |  |
| 1-Amino-1-deoxy-D-ribitol | 1-Amino-1-deoxy-D-ribitol is an intermediate in synthesizing 5-Nitroso-6-ribitylamino-2,4(1H,3H)-pyrimidinedione (), an inhibitor of lumazine synthase from spinach and the fungus Magnaporthe grisea. Group: Biochemicals. Grades: Highly Purified. CAS No. 527-47-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C5H13NO4, Molecular Weight: 151.16. US Biological Life Sciences. |  Worldwide |
| 1-Deoxy-1-[(2,6-dimethoxy-5-nitro-4-pyrimidinyl)amino]-D-ribitol | 1-Deoxy-1-[(2,6-dimethoxy-5-nitro-4-pyrimidinyl)amino]-D-ribitol is an intermediate in the synthesis of Lumazine (L473800) fluorophore. Group: Biochemicals. Grades: Highly Purified. CAS No. 669088-28-2. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C11H18N4O8. US Biological Life Sciences. | Worldwide |
| 2- ( (2, 4-Dioxo-6- ( ( (2S, 3S, 4R) -2, 3, 4, 5-tetrahydroxypentyl) amino) -1, 2, 3, 4-tetrahydropyrimidin-5-yl) imino) acetaldehyde | 2- ( (2, 4-Dioxo-6- ( ( (2S, 3S, 4R) -2, 3, 4, 5-tetrahydroxypentyl) amino) -1, 2, 3, 4-tetrahydropyrimidin-5-yl) imino) acetaldehyde is an intermediate in the biosynthesis of ribityl-lumazines. Group: Biochemicals. Grades: Highly Purified. CAS No. 1610526-17-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C11H16N4O7, Molecular Weight: 316.27. US Biological Life Sciences. | Worldwide |
| 5-Nitro-6-(D-ribitylamino)-2,4(1H,3H)-pyrimidinedione | 5-Nitro-6-(D-ribitylamino)-2,4(1H,3H)-pyrimidinedione is an intermediate in the synthesis of Lumazine fluorophore. Synonyms: 5-Nitro-6-[(ribo-2,3,4,5-tetrahydroxypentyl)amino]uracil; 1-Deoxy-1-[(2,6-Dihydroxy-5-nitro-4-pyrimidinyl)amino]ribitol; 1-Deoxy-1-[(1,2,3,6-tetrahydro-5-nitro-2,6-dioxo-4-pyrimidinyl)amino]-D-ribitol. CAS No. 52918-39-5. Molecular formula: C9H14N4O8. Mole weight: 306.23. | |
| SCR7 Pyrazine | SCR7 pyrazine also is a potent inhibitor of nonhomologous endjoining (NHEJ) mediated by DNA ligase IV. It enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro upt to 19-fold. SCR7 pyrazine is a product of spontaneous cyclization of CRISPR enhancer SCR7 first reported by Srivastava, M., et al.DNA ligase IV seals double-strand breaks during the process of nonhomologous end-joining in DNA repair. Inhibiting this function in cancer cells is one strategy to prevent deleterious cell growth. SCR7 is a small molecule inhibitor of DNA ligase IV that prevents nonhomologous end-joining by interfering with ligase binding and activating apoptosis.1 It also inhibits ligase III, but does not affect the activity of T4 DNA ligase or ligase I. SCR7 has been used to increase the rate of homology directed repair triggered by DNA double-strand breaks and to inhibit cancer cell growth in vitro (IC50s = 8-120 µM) and in mouse models when co-administered with double-strand break-inducing therapeutic compounds.1,2,3,4. Group: Biochemicals. Alternative Names: 2,3-Dihydro-6,7-diphenyl-2-thioxo-4 (1H)-pteridinone; 6,7-Diphenyl-2-thio-lumazine. Grades: Highly Purified. CAS No. 14892-97-8. Pack Sizes: 10mg. Molecular Formula: C??H??N?OS, Molecular Weight: 332.38. US Biological Life Sciences. | Worldwide |
| Terrelumamide A | Terrelumamide A is a lumazine-containing peptide fungal metabolite that has been found in A. terreus. It increases adiponectin production, a marker of insulin sensitivity, in human bone marrow mesenchymal stem cells (hBM-MSCs; EC50=37.1 μM). Synonyms: Penilumamide E. Grades: >95% by HPLC. CAS No. 1802497-05-7. Molecular formula: C20H20N6O7. Mole weight: 456.41. | |
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