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Inhibits hemozoin formation. Antimalarial. Group: Biochemicals. Alternative Names: (9Z)-. Grades: Highly Purified. CAS No. 82186-77-4. Pack Sizes: 25mg. US Biological Life Sciences.
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Lumefantrine
Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Benflumetol. CAS No. 82186-77-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0803.
Lumefantrine b-D-Glucuronide
Lumefantrine b-D-Glucuronide is an indispensable pharmaceutical compound in the study of malaria, exemplifing a glucuronide conjugate derivative of lumefantrine. Synonyms: (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-a-[(dibutylamino)methyl]-9H-fluorene-4-methanol b-D-Glucopyranosiduronic Acid. Molecular formula: C36H40Cl3NO7. Mole weight: 705.06.
Lumefantrine β-D-Glucuronide
Lumefantrine β-D-Glucuronide is a metabolite of Lumefantrine. Synonyms: (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol β-D-Glucopyranosiduronic Acid. Grades: > 95%. Molecular formula: C36H40Cl3NO7. Mole weight: 705.06.
Inhibits hemozoin formation. Antimalarial. Group: Biochemicals. Alternative Names: (9Z)-o-d18)methyl]-9H-fluorene-4-methanol; 2-(Dibutylamino-d18)-1-[2,7-dichloro-9-[1-(4-chlorophenyl)meth-(Z)-ylidene]-9H-fluoren-4-yl]ethanol; Benflumelol-d18; Benflumetol-d18; dl-Benflumelol-d18. Grades: Highly Purified. CAS No. 1185240-53-2. Pack Sizes: 1mg. US Biological Life Sciences.
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Lumefantrine glucuronide - (mixture of diasteromers)
Lumefantrine glucuronide is a complex mixture comprising diastereomers, harnessed within the pharmaceutical domain for the purpose of robustly studying the notorious scourge of malaria. Operating as a potent antimalarial compound, it remarkably displays tremendous efficacy in research of Plasmodium species. Molecular formula: C36H40Cl3NO7. Mole weight: 705.06.
Lumefantrine impurity 10
Lumefantrine impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4364-35-6. Molecular Formula: C20H11Cl3. Mole Weight: 357.66. Catalog: APB4364356.
Lumefantrine impurity 11
Lumefantrine impurity 11. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C36H40Cl3NO7. Mole Weight: 705.07. Catalog: APB11889.
Lumefantrine impurity 12
Lumefantrine impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 355841-11-1. Molecular Formula: C26H24Cl3NO. Mole Weight: 472.83. Catalog: APB355841111.
Lumefantrine impurity 13
Lumefantrine impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 53221-25-3. Molecular Formula: C23H27Cl2NO2. Mole Weight: 420.37. Catalog: APB53221253.
Lumefantrine impurity 14
Lumefantrine impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 69759-61-1. Molecular Formula: C23H29Cl2NO. Mole Weight: 406.39. Catalog: APB69759611.
Lumefantrine impurity 15
Lumefantrine impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 7012-16-0. Molecular Formula: C13H8Cl2. Mole Weight: 235.11. Catalog: APB7012160.
Lumefantrine impurity 17
Lumefantrine impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2523-44-6. Molecular Formula: C13H9Cl. Mole Weight: 200.67. Catalog: APB2523446.
Lumefantrine impurity 3
Lumefantrine impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1331642-68-2. Molecular Formula: C30H32Cl3NO. Mole Weight: 528.94. Catalog: APB1331642682.
Lumefantrine impurity 4
Lumefantrine impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1795129-61-1. Molecular Formula: C44H24Cl6O2. Mole Weight: 797.37. Catalog: APB1795129611.
Lumefantrine impurity 5
Lumefantrine impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1795128-25-4. Molecular Formula: C44H24Cl6O2. Mole Weight: 797.37. Catalog: APB1795128254.
Lumefantrine impurity 6
Lumefantrine impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1456736-33-6. Molecular Formula: C30H32Cl3NO. Mole Weight: 528.94. Catalog: APB1456736336.
Lumefantrine impurity 7
Lumefantrine impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1582279-20-6. Molecular Formula: C19H19Cl2NO2. Mole Weight: 364.27. Catalog: APB1582279206.
Lumefantrine impurity 8
Lumefantrine impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H13Cl3O. Mole Weight: 399.7. Catalog: APB11888.
Lumefantrine impurity 9
Lumefantrine impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 252990-29-7. Molecular Formula: C22H13Cl3O. Mole Weight: 399.7. Catalog: APB252990297.
9-Des[ (4-chlorophenyl) methylene]-9-oxo lumefantrine. Group: Biochemicals. Alternative Names: 2,7-Dichloro-4-[2-(dibutylamino)-1-hydroxyethyl]-9H-fluoren-9-one; Lumefantrine keto impurity. Grades: Highly Purified. CAS No. 53221-25-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C23H27Cl2NO2. US Biological Life Sciences.
Worldwide
Desbutyl Lumefantrine
A metabolite of Lumefantrine. Group: Biochemicals. Alternative Names: α -[ (Butylamino) methyl]-2, 7-dichloro-9-[ (4-chlorophenyl) methylene]-9H-fluorene-4-methanol. Grades: Highly Purified. CAS No. 252990-19-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desbutyl Lumefantrine
Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desbutyl-benflumetol. CAS No. 355841-11-1. Pack Sizes: 1 mg. Product ID: HY-12781.
Desbutyl Lumefantrine-d9
A labeled metabolite of Lumefantrine. Group: Biochemicals. Alternative Names: α -[ (Butylamino-d9) methyl]-2, 7-dichloro-9-[ (4-chlorophenyl) methylene]-9H-fluorene-4-methanol. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(Z)-Desbutyl Lumefantrine
(Z)-Desbutyl Lumefantrine is a metabolite of Lumefantrine. Synonyms: (Z)-Desbutyl-benflumetol; (9Z)-α-[(Butylamino)methyl]-2,7-dichloro-9-[(4-chlorophenyl)methylene]-9H-fluorene-4-methanol. Grades: > 95%. CAS No. 355841-11-1. Molecular formula: C26H24Cl3NO. Mole weight: 472.83.
2,7-Dichlorofluorene
Intermediate in the production of Lumefantrine. Group: Biochemicals. Alternative Names: 2,7-Dichloro-9H-fluorene; NSC 73077. Grades: Highly Purified. CAS No. 7012-16-0. Pack Sizes: 2.5g. US Biological Life Sciences.
2-(Dibutylamino)-1-(2,7-dichloror-9H-fluoren-4-yl)ethanol is an impurity formed during the synthesis of Lumefantrine, a fluorene derivative belonging to the aryl amino alcohol class of anti-malarial drugs. Synonyms: 2,7-Dichloro-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol. Grades: > 95%. CAS No. 69759-61-1. Molecular formula: C23H29Cl2NO. Mole weight: 406.39.
2-(Dibutylamino)-1-(2,7-dichloror-9H-fluoren-4-yl)ethanol is an impurity formed during the synthesis of Lumefantrine (L474000), a fluorene (F462000) derivative belonging to the aryl amino alcohol class of anti-malarial drugs. Group: Biochemicals. Alternative Names: 2,7-Dichloro-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol. Grades: Highly Purified. CAS No. 69759-61-1. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
5-Oxiranyl-2,7-dichlorofluorene
5-Oxiranyl-2,7-dichlorofluorene is a Lumefantrine intermediate. Synonyms: (2,7-Dichloro-9H-fluoren-4-yl)oxirane; 2-(2,7-Dichloro-9H-fluoren-4-yl)oxirane. Grades: > 95%. CAS No. 53221-14-0. Molecular formula: C15H10Cl2O. Mole weight: 277.15.
5-Oxiranyl-2,7-dichlorofluorene
Lumefantrine intermediate. Group: Biochemicals. Alternative Names: (2,7-Dichloro-9H-fluoren-4-yl)oxirane; 2-(2,7-Dichloro-9H-fluoren-4-yl)oxirane. Grades: Highly Purified. CAS No. 53221-14-0. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Artemether
Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.Target: AntiparasiticArtemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. Artemether exhibits the highest activity against juvenile stages of the parasites, while adult worms are significantly less susceptible. There was no indication of neurotoxicity following repeated high doses of artemether given fortnightly for up to 5 months. Artemether-integrated with other control strategies-has considerable potential for reducing the current burden of schistosomiasis in different epidemiological settings. There were remarkably inhibitory effects of artmeter on brain glioma growth and angiogenesis in SD rats and the mechanism that artemether inhibited brain glioma growth might be penetrating the blood-brain barrier and inhibiting angiogenesis. Group: Inhibitors. CAS No. 71963-77-4. Molecular formula: C16H26O5. Mole weight: 298.37. Appearance: Solid. Purity: 0.98. Canonical SMILES: C[C@H]1[C@@H] (OC)O[C@@]2 ([H])[C@]34[C@@] ([C@H] (C)CC[C@]41[H]) ([H])CC[C@@] (O2) (C)OO3. Catalog: ACM71963774.
Benflumetol
Lumefantrine inhibits hemozoin formation. It is an antimalarial. Uses: Benflumetol is used in combination with artemether for improved efficacy. it inhibits hemozoin formation. it is is an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. Synonyms: (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol; 2-Dibutylamino-1-[2,7-dichloro-9-[1-(4-chlorophenyl)meth-(Z)-ylidene]- 9H-fluoren-4-yl]ethanol; Benflumelol; Benflumetol; dl-Benflumelol. Grades: USP. CAS No. 82186-77-4. Molecular formula: C30H32Cl3NO. Mole weight: 528.94.