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Inhibits hemozoin formation. Antimalarial. Group: Biochemicals. Alternative Names: (9Z)-. Grades: Highly Purified. CAS No. 82186-77-4. Pack Sizes: 25mg. US Biological Life Sciences.
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Lumefantrine
Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Benflumetol. CAS No. 82186-77-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0803.
Lumefantrine-d18
Inhibits hemozoin formation. Antimalarial. Group: Biochemicals. Alternative Names: (9Z)-o-d18)methyl]-9H-fluorene-4-methanol; 2-(Dibutylamino-d18)-1-[2,7-dichloro-9-[1-(4-chlorophenyl)meth-(Z)-ylidene]-9H-fluoren-4-yl]ethanol; Benflumelol-d18; Benflumetol-d18; dl-Benflumelol-d18. Grades: Highly Purified. CAS No. 1185240-53-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Lumefantrine-[d18]
Lumefantrine-[d18] is the labelled analogue of Lumefantrine, which is an antimalarial drug. Synonyms: Lumefantrine D18; Benflumetol D18; (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino-d18)methyl]-9H-fluorene-4-methanol; 2-(Dibutylamino-d18)-1-[2,7-dichloro-9-[1-(4-chlorophenyl)meth-(Z)-ylidene]-9H-fluoren-4-yl]ethanol. Grade: 98% by HPLC; 98% atom D. CAS No. 1185240-53-2. Molecular formula: C30H14D18Cl3NO. Mole weight: 547.05.
Lumefantrine-[d9]
Lumefantrine-[d9] is the labelled analogue of Lumefantrine, which Inhibits hemozoin formation, used as antimalarial. Synonyms: Lumefantrine D9. Grade: 98% by HPLC; 98% atom D. CAS No. 2477594-24-2. Molecular formula: C30H23D9Cl3NO. Mole weight: 538.00.
Lumefantrine impurity 3
Lumefantrine impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1331642-68-2. Molecular formula: C30H32Cl3NO. Mole weight: 528.94. Catalog: APB1331642682.
Lumefantrine Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
9-Des[ (4-chlorophenyl) methylene]-9-oxo lumefantrine. Group: Biochemicals. Alternative Names: 2,7-Dichloro-4-[2-(dibutylamino)-1-hydroxyethyl]-9H-fluoren-9-one; Lumefantrine keto impurity. Grades: Highly Purified. CAS No. 53221-25-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C23H27Cl2NO2. US Biological Life Sciences.
Worldwide
Desbutyl Lumefantrine
A metabolite of Lumefantrine. Group: Biochemicals. Alternative Names: α -[ (Butylamino) methyl]-2, 7-dichloro-9-[ (4-chlorophenyl) methylene]-9H-fluorene-4-methanol. Grades: Highly Purified. CAS No. 252990-19-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desbutyl Lumefantrine
Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desbutyl-benflumetol. CAS No. 355841-11-1. Pack Sizes: 1 mg. Product ID: HY-12781.
Desbutyl Lumefantrine-d9
A labeled metabolite of Lumefantrine. Group: Biochemicals. Alternative Names: α -[ (Butylamino-d9) methyl]-2, 7-dichloro-9-[ (4-chlorophenyl) methylene]-9H-fluorene-4-methanol. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-Desbutyl Lumefantrine-[d9] (E/Z-Mixture)
N-Desbutyl Lumefantrine-[d9] is the labelled analogue of N-Desbutyl Lumefantrine, which is a metabolite of Lumefantrine. Synonyms: N-Desbutyl Lumefantrine D9; α-[(Butylamino-d9)methyl]-2,7-dichloro-9-[(4-chlorophenyl)methylene]-9H-fluorene-4-methanol; Desbutyl Lumefantrine-d9 (E/Z-Mixture). Grade: ≥96% by HPLC; ≥98% atom D. CAS No. 1346606-35-6. Molecular formula: C26H15D9Cl3NO. Mole weight: 481.89.
(Z)-Desbutyl Lumefantrine
(Z)-Desbutyl Lumefantrine is a metabolite of Lumefantrine. Synonyms: (Z)-Desbutyl-benflumetol; (9Z)-α-[(Butylamino)methyl]-2,7-dichloro-9-[(4-chlorophenyl)methylene]-9H-fluorene-4-methanol. Grade: > 95%. CAS No. 355841-11-1. Molecular formula: C26H24Cl3NO. Mole weight: 472.83.
2,7-Dichlorofluorene
Intermediate in the production of Lumefantrine. Group: Biochemicals. Alternative Names: 2,7-Dichloro-9H-fluorene; NSC 73077. Grades: Highly Purified. CAS No. 7012-16-0. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
2-Chloro-1-(2,7-dichloro-9H-fluoren-4-yl)ethanone
An impurity of Lumefantrine, an antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. Synonyms: 2-chloro-1-(2,7-dichloro-9H-fluoren-4-yl)ethan-1-one; 4-chloroacetyl-2,7-dichlorofluorene. Grade: 95%. CAS No. 131023-37-5. Molecular formula: C15H9Cl3O. Mole weight: 311.59.
2-(Dibutylamino)-1-(2,7-dichloror-9H-fluoren-4-yl)ethanol is an impurity formed during the synthesis of Lumefantrine, a fluorene derivative belonging to the aryl amino alcohol class of anti-malarial drugs. Synonyms: 2,7-Dichloro-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol. Grade: > 95%. CAS No. 69759-61-1. Molecular formula: C23H29Cl2NO. Mole weight: 406.39.
2-(Dibutylamino)-1-(2,7-dichloror-9H-fluoren-4-yl)ethanol is an impurity formed during the synthesis of Lumefantrine (L474000), a fluorene (F462000) derivative belonging to the aryl amino alcohol class of anti-malarial drugs. Group: Biochemicals. Alternative Names: 2,7-Dichloro-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol. Grades: Highly Purified. CAS No. 69759-61-1. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
5-Oxiranyl-2,7-dichlorofluorene
5-Oxiranyl-2,7-dichlorofluorene is a Lumefantrine intermediate. Synonyms: (2,7-Dichloro-9H-fluoren-4-yl)oxirane; 2-(2,7-Dichloro-9H-fluoren-4-yl)oxirane. Grade: > 95%. CAS No. 53221-14-0. Molecular formula: C15H10Cl2O. Mole weight: 277.15.
5-Oxiranyl-2,7-dichlorofluorene
Lumefantrine intermediate. Group: Biochemicals. Alternative Names: (2,7-Dichloro-9H-fluoren-4-yl)oxirane; 2-(2,7-Dichloro-9H-fluoren-4-yl)oxirane. Grades: Highly Purified. CAS No. 53221-14-0. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Artemether
Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.Target: AntiparasiticArtemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. Artemether exhibits the highest activity against juvenile stages of the parasites, while adult worms are significantly less susceptible. There was no indication of neurotoxicity following repeated high doses of artemether given fortnightly for up to 5 months. Artemether-integrated with other control strategies-has considerable potential for reducing the current burden of schistosomiasis in different epidemiological settings. There were remarkably inhibitory effects of artmeter on brain glioma growth and angiogenesis in SD rats and the mechanism that artemether inhibited brain glioma growth might be penetrating the blood-brain barrier and inhibiting angiogenesis. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 71963-77-4. Molecular formula: C16H26O5. Mole weight: 298.37. Purity: 0.98. Canonical SMILES: C[C@H]1[C@@H](OC)O[C@@]2([H])[C@]34[C@@]([C@H](C)CC[C@]41[H])([H])CC[C@@](O2)(C)OO3. Product ID: ACM71963774. Alfa Chemistry ISO 9001:2015 Certified.
Benflumetol
Lumefantrine inhibits hemozoin formation. It is an antimalarial. Uses: Benflumetol is used in combination with artemether for improved efficacy. it inhibits hemozoin formation. it is is an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. Synonyms: (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol; 2-Dibutylamino-1-[2,7-dichloro-9-[1-(4-chlorophenyl)meth-(Z)-ylidene]- 9H-fluoren-4-yl]ethanol; Benflumelol; Benflumetol; dl-Benflumelol. Grade: USP. CAS No. 82186-77-4. Molecular formula: C30H32Cl3NO. Mole weight: 528.94.