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m7GDP is an esteemed compound commodity widely employed within the biomedical realm, epitomizes an indispensable medium in sundry enzymatic reactions, exerting a momentous influence on the intricate processes of RNA transcription and translation. Its invaluable utility extends to the research of viral afflictions, notably influenza and respiratory syncytial virus (RSV). Additionally, it facilitates meticulous investigations pertaining to mRNA processing and the cap-dependent translation mechanism. Synonyms: 7-methyl-7,8-dihydroguanosine-5'-diphosphate; 7-methylguanosine diphosphate; N7-methyl-GDP. Grades: 95%. CAS No. 117723-13-4. Molecular formula: C11H19N5O11P2. Mole weight: 459.24.
Ant-m7GDP
Ant-m7GDP is an exceptional pharmacological compound characterized by its profound capacity to combat viral infections. This awe-inspiring compound exhibits an unparalleled proclivity for selectively targeting and disrupting the intricate guanosine triphosphate cap structures, thereby impeding the vital process of viral mRNA capping. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C18H22N6O12P2 (free acid). Mole weight: 576.35 (free acid).
EDA-m7GDP
EDA-m7GDP emerges as a prominent biochemical entity extensively employed in studying influenza and hepatitis C. This compound assumes a paramount role in inhibiting the replication of virals. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2(free acid). Mole weight: 544.33 (free acid).
EDA-m7GDP - 5/6-TAMRA
EDA-m7GDP - 5/6-TAMRA is a fluorescently labeled ligand used in binding assays to study interaction with GTPases, specifically the RAS family. It is also utilized in studying mRNA decapping enzymes such as the DcpS enzyme. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with 5/6-TAMRA. Grades: ≥ 95 % by HPLC. Molecular formula: C39H43N9O16P2(free acid). Mole weight: 955.76 (free acid).
EDA-m7GDP - 5-FAM
EDA-m7GDP is a small molecule used in the biomedicine industry for the study of RNA processing and modification. It serves as a substrate analog for RNA cap methyltransferase and is used to investigate the role of the cap structure and its modification in RNA processing. EDA-m7GDP is also used in the development of potential antiviral drugs as it inhibits viral RNA cap formation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 5FAM, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C35H33N7O18P2(free acid). Mole weight: 901.63 (free acid).
EDA-m7GDP - 6-FAM
EDA-m7GDP - 6-FAM is a fluorescently labeled analog of the mRNA cap structure, used in biomedicine to study and track mRNA metabolism and protein synthesis. It can also aid in the identification and screening of inhibitors for mRNA capping enzymes, and has potential use in the development of drugs for diseases linked to aberrant mRNA processing, such as cancer and viral infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with 6 FAM, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C35H33N7O18P2(free acid). Mole weight: 901.63 (free acid).
EDA-m7GDP - 6-JOE
EDA-m7GDP - 6-JOE, a revered biochemical reagent in the realm of biomedical research, is meticulously employed to scrutinize the immensely intricate cogency of mRNA cap structure in the context of gene expression. Inevitably, the multifarious uses of this mystical compound are riveting, given its intrinsic importance as a formidable inhibitor of cap-dependent translation. Additionally, EDA-m7GDP - 6-JOE is a pragmatic model to study the elusive mechanisms of viral mRNA translation; and to further delve into, with precision, the molecular basis of grievous ailments such as cancer and viral infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with 6-JOE, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C37H35Cl2N7O20P2(free acid). Mole weight: 1029.08 (free acid).
EDA-m7GDP - 6-ROX
EDA-m7GDP-6-ROX, a fluorescently-labeled GDP derivative, is a widely-utilized biochemistry research tool for probing the complex interactions involving GTPase-associated proteins and their respective GTPases. Its usage is heavily linked to unraveling intricate signaling pathways implicated in the pathogenesis of dreadful diseases like cancer and neurodegeneration. Through its utilization, valuable insights into the underlying mechanisms of these ailments can be obtained. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with 6-ROX. Grades: ≥ 95 % by HPLC. Molecular formula: C47H51N9O16P2(free acid). Mole weight: 1059.92 (free acid).
EDA-m7GDP - ATTO-390
EDA-m7GDP - ATTO-390 is a fluorescent analog of m7GDP, a cap structure found at the 5' end of mRNA. It can be used to study cap-dependent translation initiation in cells, as well as drug screening assays for compounds that either enhance or inhibit protein synthesis. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 390, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C34H46N8O15P2(free acid). Mole weight: 868.73 (free acid).
EDA-m7GDP - ATTO-425
EDA-m7GDP - ATTO-425, a fluorescent nucleotide analogue widely employed in biochemical studies of RNA metabolism, finds a unique utility in unravelling the molecular intricacies of RNA capping. Of equal significance is its efficacy in monitoring RNA transportation in vivo, rendering it the most sought-after choice in live cell imaging. In essence, EDA-m7GDP - ATTO-425 continues to be an indispensable tool in deciphering RNA's elusive language. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 425, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C36H48N8O17P2(free acid). Mole weight: 926.76 (free acid).
EDA-m7GDP - ATTO-465
EDA-m7GDP - ATTO-465 is a fluorescent nucleotide analog that paves the way for scientists to scrutinize RNA cap structures with great accuracy and precision. This product is widely utilized in the biomedical field, enabling researchers to investigate cap structures on mRNA molecules. Undoubtedly, this is an impressive tool in hunting down the molecular basis of malignant tumors and viral infections. In particular, EDA-m7GDP - ATTO-465's exceptional sensitivity and specificity makes it the first choice for studies of cap structures in RNA and their modification, such as those involved in gene expression regulation and viral escape. Turn to this high-performance product and gain insight into cap structures, opening up novel opportunities for therapeutic development. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 465. Grades: ≥ 95 % by HPLC. Molecular formula: C31H38N10O13P2(free acid). Mole weight: 820.64 (free acid).
EDA-m7GDP - ATTO-488
EDA-m7GDP - ATTO-488 is a fluorescent probe used in biomedical field for studying cellular signaling pathways. It specifically targets m7GDP is a modified nucleotide involved in mRNA capping. This probe enables the visualization and analysis of mRNA capping processes, which play a crucial role in gene expression regulation. It can be utilized for investigating various diseases and drug development related to mRNA metabolism and translation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C39H44N10O21P2S2(free acid). Mole weight: 1114.16 (free acid).
EDA-m7GDP - ATTO-495
EDA-m7GDP-ATTO-495 - a fluorescent analog recognized for its ability to detect RNA cap structure - has now become a hallmark of research that delves into the intricacies of RNA capping mechanisms. Its invaluable contributions extend beyond that, however, as it also plays a vital role in the study of viral infections - Dengue, West Nile, Zika, and the like - hence making it a valuable asset in the scientific community's quest for knowledge. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 495. Grades: ≥ 95 % by HPLC. Molecular formula: C35H46N10O13P2(free acid). Mole weight: 876.75 (free acid).
EDA-m7GDP - ATTO-532
EDA-m7GDP - ATTO-532 is a fluorescent analog of the 7-methylguanosine diphosphate nucleotide, widely used in biochemical and molecular biology research. This product specifically targets RNA cap-binding proteins, serving as a useful tool for the study of cap-dependent translation initiation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C43H52N10O21P2S2(free acid). Mole weight: 1171.01 (free acid).
EDA-m7GDP - ATTO-540Q
EDA-m7GDP-ATTO-540Q: a fluorescent derivative of immense value in the field of RNA structural analysis. This compound, revered for its ability to label the cap structures of RNA and detect RNA-labeling within cells, is a critical tool for those studying RNA processing and translational regulation. Scientists worldwide rely upon EDA-m7GDP-ATTO-540Q as a comprehensive fluorescent probe to facilitate their research in the field of RNA structural analysis. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 540Q, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- ATTO 540Q (free acid). Mole weight: 1084.33 (free acid).
EDA-m7GDP - ATTO-550
EDA-m7GDP - ATTO-550, a fluorescent probe commonly employed in the realm of biomedical research, serves as a powerful tool to investigate the intricate interplay between mRNA and translation initiation factors. Through its intrinsic capacity to detect and quantitate eIF4E binding to the mRNA cap structure, this versatile instrument has proven to be of paramount significance in comprehending the underlying mechanisms of cancerous and viral-induced infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 550, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 550 (free acid). Mole weight: 1119.33 (free acid).
EDA-m7GDP - ATTO-565
EDA-m7GDP - ATTO-565 is a fluorescently labeled Guanosine diphosphate (GDP) analog used for studying guanine nucleotide binding proteins (G proteins) in biomedical research. It can be utilized in the detection of G protein activation and signaling pathways related to various diseases, including cancer and neurological disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 565. Grades: ≥ 95 % by HPLC. Molecular formula: C45H51N9O16P2(free acid). Mole weight: 1035.89 (free acid).
EDA-m7GDP - ATTO-580Q
EDA-m7GDP - ATTO-580Q is a fluorescent-labeled nucleotide analog used in biomedical research to study the dynamics of mRNA cap structure and protein-RNA interactions. It is commonly used to investigate RNA translation and to screen for potential antiviral drugs targeting cap-dependent translation initiation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 580Q, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- ATTO 580Q (free acid). Mole weight: 1220.33 (free acid).
EDA-m7GDP - ATTO-590
EDA-m7GDP - ATTO-590, a fluorescent tag of immense utility in the field of biomedical research, grants an opportunity to probe deeper into the intricate interplay between the eukaryotic translation initiation factor 4E (eIF4E) and the mRNA cap structures. The luminosity of the fluorescent tag coupled with the specificity of the binding between eIF4E and the mRNA cap help researchers visualize their interactions in vivo, paving the way for novel insights into the intricate regulation of protein synthesis and new avenues for cancer therapy. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 590. Grades: ≥ 95 % by HPLC. Molecular formula: C51H59N9O16P2(free acid). Mole weight: 1116.02 (free acid).
EDA-m7GDP - ATTO-594
EDA-m7GDP - ATTO-594 is a fluorescent counterpart of the cap structure of mRNA, specifically engineered to investigate RNA processing and transportation. It offer insights into the fundamental mechanisms that regulate these vital cellular activities, enabling researchers to assess intricate interactions between key proteins and enzymes involved in RNA metabolism. Its diverse functionalities make it a promising tool for drug development and studying malignant diseases such as cancer. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 594, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 594 (free acid). Mole weight: 1331.33 (free acid).
EDA-m7GDP - ATTO-612Q
EDA-m7GDP - ATTO-612Q, a fluorescent derivative employed for bioanalytical purposes, finds significant use as an RNA cap structure detection reagent. This molecule is often implemented to investigate the engagement of cap-binding proteins. Its relevance lies in the development of drugs targeted towards cap-binding proteins in pathologies such as viral infections and malignancies. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 612Q, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- ATTO 612Q (free acid). Mole weight: 1216.33 (free acid).
EDA-m7GDP - ATTO-620
EDA-m7GDP - ATTO-620, a fluorescent labeled analog of guanosine 5'-diphosphate, facilitates the study of RNA-G protein interactions in biomedical research. Comprehending protein synthesis mechanisms is achievable since it regulates translation initiation. Investigating viral infections, as well as creating anti-viral treatments, is doable due to EDA-m7GDP - ATTO-620's versatility. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 620 (free acid). Mole weight: 1037.33 (free acid).
EDA-m7GDP - ATTO-633
EDA-m7GDP - ATTO-633, a biomedicine product, is an advanced fluorescent probe that is widely utilized in scientific research to investigate RNA molecules. Its unique properties allow it to analyze cap-binding proteins and explore their interaction with mRNA molecules. With high sensitivity and low background noise, this cutting-edge probe proves to be a vital tool for deciphering translation initiation in diseases like cancer. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 633, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 633 (free acid). Mole weight: 1077.33 (free acid).
EDA-m7GDP - ATTO-647N
EDA-m7GDP - ATTO-647N is an advanced and cutting-edge fluorescently labeled guanosine diphosphate (GDP) derivative, meticulously designed for extensive utilization, particularly for the comprehensive exploration of RNA synthesand intricate processing mechanisms. With its unparalleled capacity for visualizing and monitoring RNA molecules throughout highly intricate transcription, translation and RNA turnover procedures, EDA-m7GDP - ATTO-647N has emerged as an indispensable compoundin unraveling the complexities of RNA metabolism and dynamic dynamics. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 647N, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 647N (free acid). Mole weight: 1171.33 (free acid).
EDA-m7GDP - ATTO-655
EDA-m7GDP - ATTO-655, a complex fluorescent probe, is utilized in the biomedical field to explore the crucial role played by eukaryotic initiation factor 4E (eIF4E) and its interaction with the 5' mRNA cap structure during the process of translation initiation. Aberration in this foundation has been linked to cancer and neurological disorders. With its high sensitivity and resolution, EDA-m7GDP - ATTO-655 is invaluable for imaging and analyzing eIF4E interactions both in vitro and in vivo. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 655, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H22N7O12P2- ATTO 655 (free acid). Mole weight: 1053.33 (free acid).
EDA-m7GDP - ATTO-665
EDA-m7GDP - ATTO-665, a widely utilized fluorescent tracer compound within the field of biomedicine research, acts as a labeling agent to visualize and track RNA molecules in vivo. Frequently employed for the study of protein-RNA interaction, RNA splicing, and gene expression regulation, this product showcases its worth to researchers searching for a sophisticated and reliable means of conducting cellular inquiries. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 665, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 665 (free acid). Mole weight: 1148.33 (free acid).
EDA-m7GDP - ATTO-680
EDA-m7GDP - ATTO-680 is a fluorescent-labeled guanosine nucleotide analog that has been used for real-time monitoring of RNA synthesis and processing in living cells. It is often used in studies to investigate mRNA capping and cap-binding proteins, as well as to identify inhibitors of this process for potential use in antiviral therapies. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 680, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 680 (free acid). Mole weight: 1051.33 (free acid).
EDA-m7GDP - ATTO-700
EDA-m7GDP - ATTO-700 is an exquisitely sensitive and specialized fluorophore conjugation offering facilitating the enthralling visualization and meticulous tracking of enzymatic engagement orchestrating mRNA capping and cap-dependent translational initiation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 700, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 700 (free acid). Mole weight: 1091.33 (free acid).
EDA-m7GDP - ATTO-740
EDA-m7GDP - ATTO-740 is a highly specialized fluorescent probe that has been developed specifically for the in-depth molecular analysis of RNA cap structures. The probe binds directly and selectively to the intricate cap structure of m7GDP, delivering a remarkable visual representation of the complex pathways involved in RNA processing and translation initiation. Indeed, this cutting-edge product stands at the forefront of contemporary molecular biology research, offering promising avenues for further investigation and discovery. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 740, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 740 (free acid). Mole weight: 993.33 (free acid).
EDA-m7GDP - ATTO-MB2
EDA-m7GDP - ATTO-MB2 is a fluorescent nucleotide analog commonly used in biomedical research. It is incorporated into RNA during transcription to investigate mRNA capping. With its superior brightness and stability, EDA-m7GDP - ATTO-MB2 is ideal for visualizing RNA capping dynamics and studying mRNA processing pathways in various diseases like cancer and neurological disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO MB2, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C33H42N10O13P2S (free acid). Mole weight: 880.76 (free acid).
EDA-m7GDP - ATTO-Rho101
EDA-m7GDP is a biomedicine product used for studying RNA cap-binding proteins in drug discovery and the treatment of viral diseases such as influenza. ATTO-Rho101 is a fluorescent dye that can be conjugated to EDA-m7GDP to aid in visualization and detection in research applications. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Rho101, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C51H60N10O15P2(free acid). Mole weight: 1114.37 (free acid).
EDA-m7GDP - ATTO-Rho11
EDA-m7GDP - ATTO-Rho11 is a cutting-edge biomedical product used in the research of certain types of cancers including leukemia and lymphoma. It acts as a high-affinity fluorescent probe that allows for the visualization and analysis of the m7G-cap structure in RNA. With its exceptional specificity and sensitivity, this product greatly aids in studying RNA capping, mRNA degradation and various RNA-related cellular processes. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Rho11, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C49H60N10O15P2(free acid). Mole weight: 1090.37 (free acid).
EDA-m7GDP - ATTO-Rho12
EDA-m7GDP is a reagent used in biomedical research to study the activity and function of RNA cap-binding proteins. It is used to label and visualize cap-binding protein interactions with m7GDP, which is found on the 5' end of mRNA. This can provide insights into diseases such as cancer and viral infections, where cap-binding proteins are often dysregulated. ATTO-Rho12 is a fluorescent tag that can be used in conjunction with EDA-m7GDP to visualize these interactions in real time. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Rho12, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C55H72N10O15P2(free acid). Mole weight: 1174.47 (free acid).
EDA-m7GDP - ATTO-Rho13
EDA-m7GDP - ATTO-Rho13 is a fluorescently labeled nucleotide analog. It can be used to study the interactions between RNA and proteins, specifically the cap-binding protein eIF4E and its binding to the mRNA cap structure m7GDP. This product can aid in research on RNA processing and translation, as well as drug discovery for diseases related to dysregulation of protein synthesis such as cancer and neurological disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Rho13, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C55H68N10O15P2(free acid). Mole weight: 1170.43 (free acid).
EDA-m7GDP - ATTO-Rho14
EDA-m7GDP - ATTO-Rho14 is a specialized biomedical product used in the study of RNA capping enzymes. Specifically, it is used as a fluorescent substrate for monitoring the activity of RNA cap guanine-N7 methyltransferase (RNMT) and other related enzymes. This product can potentially aid in the development of new drugs targeting RNA capping enzymes and diseases related to their dysfunction. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Rho14, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C55H64Cl4N10O15P2(free acid). Mole weight: 1306.28 (free acid).
EDA-m7GDP - ATTO-Rho6G
EDA-m7GDP - ATTO-Rho6G, a fluorescent-labeled probe, offers a valuable tool for exploring RNA capping enzymes and unraveling the intricacies of mRNA formation. With the capacity to identify factors integral to vital processes such as mRNA processing, translation initiation, and immune evasion, this discreet yet powerful resource is a must-have for any researcher seeking to expand knowledge in drug target discovery, drug development, and viral infection diagnostics. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Rho6G, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C45H56N10O15P2(free acid). Mole weight: 1038.34 (free acid).
EDA-m7GDP - ATTO-Thio12
EDA-m7GDP, a nucleotide analog utilized for biochemical research, is renowned for its ability to bind to proteins engaged in mRNA interaction. It serves as a useful tool for studying the translation initiation and turnover of mRNA. ATTO-Thio12, a fluorescent labeling reagent, can be conjoined with EDA-m7GDP to assist in imaging and detection applications. This product is widely utilized in drug discovery and RNA biology investigations. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO Thio12. Grades: ≥ 95 % by HPLC. Molecular formula: C43H52N10O14P2S (free acid). Mole weight: 1026.94 (free acid).
EDA-m7GDP - Biotin
EDA-m7GDP - Biotin is a compound widely used in Biomedicine. This compound is utilized to study RNA cap structure. EDA-m7GDP - Biotin works as a probe that selectively binds to cap structures on RNA molecules. Researchers utilize this compound in experiments to isolate and identify proteins that interact with the RNA cap structure. This compound is applied in a range of studies related to viral infections and cancer. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-N7-methyl-guanosine-5'-diphosphate - Biotin, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C24H37N9O14P2S (free acid). Mole weight: 769.61 (free acid).
EDA-m7GDP (Biotin)
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: 2/3-O-(2-Aminoethyl-carbamoyl)-N7-methyl-guanosine-5-diphosphate (Biotin), Triethylammonium Salt. Grades: Highly Purified. Pack Sizes: 50ul. US Biological Life Sciences.
Worldwide
EDA-m7GDP - Cy3
EDA-m7GDP - Cy3, a fluorescent probe designed for biochemical studies, serves the essential purpose of RNA cap structure detection. Its unique composition featuring EDA-m7GDP, a 5' end of messenger RNA mimic, and Cy3, a potent signal emitter under specific conditions, provides researchers with a valuable tool for determining the efficacy of drugs that inhibit RNA capping. Moreover, the product's potential for correlating with treating viral infections and cancer makes it a critical component in scientific investigations. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with Cy3. Grades: ≥ 95 % by HPLC. Molecular formula: C45H59N9O19P2S2(free acid). Mole weight: 1156.07 (free acid).
EDA-m7GDP - Cy5
EDA-m7GDP - Cy5 is a fluorescent dye conjugate used in the biomedical industry for labeling and visualizing RNA molecules. It enables the detection and imaging of specific messenger RNA (mRNA) transcripts is aiding in research related to gene expression, cellular processes and disease mechanisms. EDA-m7GDP - Cy5 is particularly valuable in studying RNA translation and degradation pathways, as well as in identifying mRNA targets for researchs. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C47H61N9O19P2S2(free acid). Mole weight: 1182.11 (free acid).
EDA-m7GDP - DY-480XL
EDA-m7GDP - DY-480XL is a valuable tool in biomedicine, targeting a specific class of diseases caused by dysregulation of mRNA translation. It is utilized as an inhibitor of the eIF4E-eIF4G complex, preventing the initiation of cap-dependent translation. This product aids in the study and development of potential treatments for cancer, viral infections, and other diseases involving dysregulated translation processes. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with DY 480XL, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C40H51N9O18P2S (free acid). Mole weight: 1039.90 (free acid).
EDA-m7GDP - DY-485XL
EDA-m7GDP - DY-485XL is serving as a modified guanosine nucleotide analog, aidding in delving into the functional repercussions of mRNA cap structure modifications and widely applied to research of diseases such as cancer and viral infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with DY 485XL. Grades: ≥ 95 % by HPLC. Molecular formula: C39H51N9O18P2S (free acid). Mole weight: 1027.89 (free acid).
EDA-m7GDP - DY-751
EDA-m7GDP - DY-751 is a potent inhibitor designed for biomedical research. It is commonly used to block the activity of m7GDP. This compound has shown potential in treating diseases related to abnormal m7GDP signaling, including various cancers and viral infections. With its high purity and stability, EDA-m7GDP - DY-751 is an essential tool for studying mRNA capping and its implications in disease. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with DY 751, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C56H73N9O20P2S2(free acid). Mole weight: 1317.39 (free acid).
EDA-m7GDP - DY-776
EDA-m7GDP - DY-776 is an inhibitor extensively employed in the biomedical sector to study cancer combat. With its remarkable efficacy, it precisely homes in on the m7GDP binding site, inducing disruption of the RNA cap complex. Consequently, it thwarts mRNA translation, while simultaneously facilitating apoptosis within malignant cells. Encouraging outcomes from preclinical investigations have established EDA-m7GDP - DY-776 as a promising avenue for potential therapeutic advantages against an assortment of cancer variants. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with DY 776. Grades: ≥ 95 % by HPLC. Molecular formula: C58H69N9O20P2S2(free acid). Mole weight: 1338.30 (free acid).
EDA-m7GDP - DYQ-660
EDA-m7GDP - DYQ-660 is a substrate analog of the capping enzyme finding extensive applications in investigating RNA cap modification. EDA-m7GDP - DYQ-660 can be used to unravel profound insights into the intricate role of cap structures throughout RNA processing and translation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with DYQ 660, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C53H54N9O20P3S (free acid). Mole weight: 1194.15 (free acid).
EDA-m7GDP - DYQ-661
EDA-m7GDP - DYQ-661 is a compelling compound exhibiting high selectivity. It acts upon an intriguing class of genetic regulatory enzymes, showcasing showcases inhibitory efficacy against cancer cells. Mechanistically, EDA-m7GDP effectively curbs the activity of DYQ-661, a pivotal player in neoplastic progression and cellular endurance. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with DYQ 661, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C53H64N9O20P2S2(Anion). Mole weight: 1273.20 (Anion).
EDA-m7GDP - MANT
EDA-m7GDP - MANT is a crucial compound commonly employed to study the binding characteristics and functions of GTPase-activating proteins (GAPs) during the signaling pathway related to m7GDP. This product plays a pivotal role in the investigation of key drugs and diseases involved in the manipulation of GTPase activity. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with MANT, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C22H30N8O13P2(free acid). Mole weight: 676.47 (free acid).
EDA-m7GDP - OYSTER-656
EDA-m7GDP - OYSTER-656, an artificially produced nucleotide analogue. It has unique capacities to elucidate cap-dependent protein synthesis and modification within cells stands unrivalled. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with OYSTER 656, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- OYSTER 656 (free acid). Mole weight: 1261.33 (free acid).
EDA-m7GDP - Texas Red
EDA-m7GDP - Texas Red is a fluorescent probe widely used in biomedicine to study RNA cap structures and reveal functional characteristics of RNA methyltransferase activity. It can be used to detect methylated guanine nucleotides in cells and tissues, aiding the development of new therapies for various viral diseases. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with Texas Red, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C51H62N10O19P2S2-(free acid). Mole weight: 1245.17 (free acid).
Decapping of mRNA is a critical step in eukaryotic mRNA turnover. The enzyme is unable to cleave a free cap structure (m7GpppG). The enzyme from Vaccinia virus is synergistically activated in the presence of Mg2+ and Mn2+. Group: Enzymes. Synonyms: Dcp2; NUDT16; D10 protein; D9 protein; D10 decapping enzyme; decapping enzyme; m7GpppN-mRNA hydrolase; m7GpppN-mRNA m7GDP phosphohydrolase. Enzyme Commission Number: EC 3.6.1.62. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4635; 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase; EC 3.6.1.62; Dcp2; NUDT16; D10 protein; D9 protein; D10 decapping enzyme; decapping enzyme; m7GpppN-mRNA hydrolase; m7GpppN-mRNA m7GDP phosphohydrolase. Cat No: EXWM-4635.
7-Methylguanosine 5'-diphosphate sodium
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 7-Methyl-GDP sodium; m7GDP sodium. CAS No. 104809-16-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141472.
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