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| Product | Description | |
|---|---|---|
| Macitentan | Macitentan (ACT-064992) is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-064992. CAS No. 441798-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14184. |  |
| Macitentan | Macitentan. Group: Biochemicals. Alternative Names: N-[5- (4-Bromophenyl) -6-[2-[ (5-bromo-2-pyrimidinyl) oxy]ethoxy]-4-pyrimidinyl]-N'-propyl-Sulfamide; ACT 064992. Grades: Highly Purified. CAS No. 441798-33-0. Pack Sizes: 5mg. Molecular Formula: C19H20Br2N6O4S, Molecular Weight: 588.27. US Biological Life Sciences. |  Worldwide |
| Macitentan-[d4] | Macitentan-[d4] is the labelled analogue of Macitentan. Macitentan, is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Synonyms: Macitentan D4; N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propyl-Sulfamide d4. Grade: 98% by HPLC; 98% atom D. CAS No. 1258428-05-5. Molecular formula: C19H16D4Br2N6O4S. Mole weight: 592.30. |  |
| Macitentan Impurity 16 | Macitentan Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1393813-42-7. Molecular formula: C13H14BrClN4O2S. Mole weight: 405.7. Catalog: APB1393813427. |  |
| Macitentan Impurity 21 | Macitentan Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1393813-43-8. Molecular formula: C15H19BrN4O4S. Mole weight: 431.3. Catalog: APB1393813438. | |
| Macitentan Impurity 29 (Benzyl alcohol) | Macitentan Impurity 29 (Benzyl alcohol). Uses: For analytical and research use. Group: Impurity standards. CAS No. 100-51-6. Molecular formula: C7H8O. Mole weight: 108.14. Catalog: APB100516. | |
| Macitentan Impurity 34 | Macitentan Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1393813-40-5. Molecular formula: C8H18N2O4S. Mole weight: 238.3. Catalog: APB1393813405. | |
| Macitentan Impurity 41 | Macitentan Impurity 41. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246922-88-2. Molecular formula: C6H7BrN2O2. Mole weight: 219.04. Catalog: APB1246922882. | |
| Macitentan Intermediate 3 | Macitentan Intermediate 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1393813-41-6. Molecular formula: C3H9KN2O2S. Mole weight: 176.28. Catalog: APB1393813416. | |
| N-Despropyl Macitentan-[d4] | N-Despropyl Macitentan-[d4] is the labelled analogue of N-Despropyl Macitentan, which is an active metabolite of Macitentan. N-Despropyl-macitentan is part of the family of endothelin receptor antagonist that allows for treatment of pulmonary arterial hypertension (PAH). Synonyms: Macitentan ACT-132577 D4; N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-sulfamide-d4; N-Despropyl Macitentan-d4; Aprocitentan D4. Grade: 98% HPLC. Molecular formula: C16H10D4Br2N6O4S. Mole weight: 550.22. | |
| O-Desbromo-pyrimidinyl Macitentan-d4 | O-Desbromo-pyrimidinyl Macitentan-d4 is the isotope labelled analog of O-Desbromo-pyrimidinyl Macitentan (D282025), which is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H15D4BrN4O4S, Molecular Weight: 435.33. US Biological Life Sciences. | Worldwide |
| 2- [ [5- (4-Bromophenyl) -6-chloro-4-pyrimidinyl] oxy] ethanol | 2- [ [5- (4-Bromophenyl) -6-chloro-4-pyrimidinyl] oxy] ethanol is a useful reagent in preparation of macitentan. Group: Biochemicals. Grades: Highly Purified. CAS No. 1642873-04-8. Pack Sizes: 5mg, 25mg. Molecular Formula: C12H10BrClN2O2, Molecular Weight: 329.58. US Biological Life Sciences. | Worldwide |
| 5-(4-bromophenyl)-6-[2-(5-chloropyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine | It is an impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Synonyms: N-[5-(4-Bromophenyl)-6-[2-[(5-chloro-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide; Macitentan Impurity 05. CAS No. 2443747-63-3. Molecular formula: C19H20BrClN6O4S. Mole weight: 543.82. | |
| 5-(4-phenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine | It is an impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Synonyms: Sulfamide, N-[6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-5-phenyl-4-pyrimidinyl]-N'-propyl-; Macitentan Impurity 10. CAS No. 2300968-87-8. Molecular formula: C19H21BrN6O4S. Mole weight: 509.38. | |
| 5-(4-phenyl)-6-[2-(pyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine | It is an impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Synonyms: Macitentan Impurity 09. CAS No. 2300968-85-6. Molecular formula: C19H22N6O4S. Mole weight: 430.48. | |
| Aprocitentan | Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual ETA/ETB antagonist with IC 50 s of 3.4 nM and 987 nM, and pA 2 valus of 6.7 and 5.5, respectively. Aprocitentan is an antihypertensive agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-132577. CAS No. 1103522-45-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15895. | |
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