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Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: 4arm-PEG-MAL, 4arm-PEG-Maleimide. Molecular formula: average Mn 10000.
4arm-PEG20K-Maleimide
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: 4arm-PEG-MAL, 4arm-PEG-Maleimide. Molecular formula: average Mn 20000.
4arm-PEG40K-Maleimide
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: 4arm-PEG-MAL, 4arm-PEG-Maleimide. Molecular formula: average Mn 40000.
5'-(3-MAL-PEG2-aminobutanoate)-floxuridine
A derivative of Floxuridine. Floxuridine is a prodrug that is rapidly catabolized in vivo to 5-fluorouracil when administered by rapid injection. Synonyms: 5'-(3-MAL-PEG2-aminobutanoate)-floxuridine. Grades: > 95%. Molecular formula: C29H42FN5O13. Mole weight: 687.68.
8arm-PEG10K-Maleimide
8arm-PEG10K-Maleimide. Group: Poly(ethylene glycol) and poly(ethylene oxide).
8arm-PEG20K-Maleimide
8arm-PEG20K-Maleimide. Group: Poly(ethylene glycol) and poly(ethylene oxide).
8arm-PEG40K-Maleimide
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: 8arm-PEG-Maleimide. Molecular formula: average Mn 40000.
Alkyne-PEG3500-MAL
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide).
Alkyne-PEG4-maleimide
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609651-90-2. Pack Sizes: 100 mg. Product ID: HY-133399.
DBCO-PEG4-Maleimide
DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1480516-75-3. Pack Sizes: 25 mg. Product ID: HY-120770.
DSPE-PEG2000-Mal ammonium
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium. CAS No. 474922-22-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144004.
DSPE-PEG5000-Mal ammonium
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents [1] [2]. DSPE-PEG5000-Mal ammonium contains PEG5000. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium. CAS No. 474922-22-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144004A.
Mal-amido-PEG9-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2569576-12-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140976A.
Maleimide-PEG4-NHS
This molecular is a sulfhydryl and amine reactive heterofuncational PEG linker. The chemical bonds that formed through Maleimide-PEG4-NHS linker are very stable. The NHS ester reacts with amino groups at pH 7-9 to form stable amide bond. In addiction, the maleimide reacts with thiol groups at pH 6.5-7.5 to form stable thiol-ether bond. Maleimide-PEG4-NHS is a very useful linker for various biomolecule crosslinking applications (such as to make ADCs (antibody drug conjugates.)). Uses: Useful linker for various biomolecule crosslinking applications. Synonyms: Maleimide-PEG4-NHS; MAL-PEG4-NHS; Maleimide PEG NHS; MAL-PEG-NHS; Maleimido-Tetra(Ethylene Glycol)?-Acetic Acid NHS ester;2,5-dioxopyrrolidin-1-yl 14-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxatetradecanoate. Grades: 98%. CAS No. 1286754-10-6. Molecular formula: C18H24N2O10. Mole weight: 428.39.
Maleimide-PEG5K-OH
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: MAL-PEG-OH, Maleimide, Maleimide-PEG-OH. Molecular formula: average Mn 5000.
Mal-NH-PEG12-acid. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 871133-36-7. Molecular formula: C34H60N2O17. Mole weight: 768.39. Purity: 95%+. Product ID: ACM871133367. Alfa Chemistry ISO 9001:2015 Certified.
Mal-NH-PEG4-acid
Mal-NH-PEG4-acid. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 1263045-16-4. Molecular formula: C18H28N2O9. Mole weight: 416.18. Purity: 95%+. Product ID: ACM1263045164. Alfa Chemistry ISO 9001:2015 Certified.
Mal-NH-PEG4-NHS ester
Mal-NH-PEG4-NHS ester. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 756525-99-2. Molecular formula: C22H31N3O11. Mole weight: 513.2. Purity: 95%+. Product ID: ACM756525992-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: 1-Maleinimido-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oic acid succinimidyl ester.
Mal-NH-PEG8-NHS ester
Mal-NH-PEG8-NHS ester. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 756525-93-6. Molecular formula: C30H47N3O15. Mole weight: 689.71. Purity: 95%+. Product ID: ACM756525936. Alfa Chemistry ISO 9001:2015 Certified.
Mal-PEG12-NHS ester
Mal-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2669737-09-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140963.
Mal-PEG1-NHS ester
Mal-PEG1-NHS ester. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 1807518-72-4. Molecular formula: C13H14N2O7. Mole weight: 310.26. Purity: 95%+. Product ID: ACM1807518724. Alfa Chemistry ISO 9001:2015 Certified.
MAL-PEG2000-B-PLA2000
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide).
MAL-PEG2000-NH2TFA
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Molecular formula: average Mn 2000. ≥95%.
Mal-PEG24-NHS ester
Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226733-37-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135819.
Mal-PEG2-acid
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule [1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374666-32-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-130442.
Mal-PEG2-acid
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Mal-PEG2-CH2CH2COOH. Product Category: Other PEG Linkers. Appearance: Liquid. CAS No. 1374666-32-6. Molecular formula: C11H15NO6. Mole weight: 257.24. Purity: >90%. IUPACName: 3-[2-[2-(2,5-Dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid. Canonical SMILES: C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O. Density: 1.3±0.1 g/cm3. Product ID: ACM1374666326. Alfa Chemistry ISO 9001:2015 Certified.
Mal-PEG2-NH2 TFA
Mal-PEG2-NH2 (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 660843-23-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-35261A.
Mal-PEG2-NHS
Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 329364-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138430.
Mal-PEG2-NHS ester
Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate. Product Category: Azido PEG Linkers. Appearance: Liquid. CAS No. 1433997-01-3. Molecular formula: C15H18N2O8. Mole weight: 354.31. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCN2C(=O)C=CC2=O. Density: 1.4±0.1 g/cm3. Product ID: ACM1433997013. Alfa Chemistry ISO 9001:2015 Certified.
Mal-PEG2-Val-Cit-PABA-PNP
Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345681-52-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131156.
Mal-PEG2-Val-Cit-PAB-OH
Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055041-38-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130222.
Mal-PEG4
Mal-PEG4. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 1421933-37-0. Molecular formula: C13H20NO6. Mole weight: 273.28. Purity: 95%+. Product ID: ACM1421933370. Alfa Chemistry ISO 9001:2015 Certified.
Mal-?PEG4-?NHS ester
Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1325208-25-0. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-126505.
Mal-PEG4-NHS ester
Mal-PEG4-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 4-unit PEG and an NHS ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,7,10,13-Tetraoxapentadecanoic acid, 15-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester. Product Category: Other PEG Linkers. Appearance: Liquid. CAS No. 1325208-25-0. Molecular formula: C19H26N2O10. Mole weight: 442.4. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCN2C(=O)C=CC2=O. Density: 1.4±0.1 g/cm3. Product ID: ACM1325208250. Alfa Chemistry ISO 9001:2015 Certified.
Mal-PEG5-acid
Mal-PEG5-acid. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 518044-41-2. Molecular formula: C15H23NO8. Mole weight: 345.35. Purity: 95%+. Product ID: ACM518044412. Alfa Chemistry ISO 9001:2015 Certified.
Mal-PEG5-PFP ester
Mal-PEG5-PFP ester. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 1415800-42-8. Molecular formula: C21H22F5NO8. Mole weight: 511.39. Purity: 95%+. Product ID: ACM1415800428. Alfa Chemistry ISO 9001:2015 Certified.
Mal-PEG5-t-butyl ester
Mal-PEG5-t-butyl ester. Uses: Designed for use in research and industrial production. Product Category: t-butyl Ester PEG Linkers. CAS No. 518044-36-5. Molecular formula: C19H31NO8. Mole weight: 401.45. Purity: 95%+. Product ID: ACM518044365. Alfa Chemistry ISO 9001:2015 Certified.
Mal-PEG6-NHS ester
Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,5-Dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate. Product Category: Other PEG Linkers. Appearance: Liquid. CAS No. 1599472-25-9. Molecular formula: C23H34N2O12. Mole weight: 530.5. Purity: >90%. IUPACName: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate. Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCN2C(=O)C=CC2=O. Density: 1.3±0.1 g/cm3. Product ID: ACM1599472259. Alfa Chemistry ISO 9001:2015 Certified.
Mal-PEG7-acid
Mal-PEG7-acid. Uses: Designed for use in research and industrial production. Product Category: Acid PEG Linkers. CAS No. 518044-42-3. Molecular formula: C19H31NO10. Mole weight: 433.45. Purity: 95%+. Product ID: ACM518044423. Alfa Chemistry ISO 9001:2015 Certified. Categories: Mal-PEG6-Acid.
Mal-PEG8-acid
Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 1818294-46-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-130334.
Mal-PEG8-NHS ester
Mal-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055033-05-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-126887.
Mal-PEG8-NHS ester
Mal-PEG8-NHS ester. Uses: Designed for use in research and industrial production. Product Category: NHS Ester PEG Linkers. CAS No. 2055033-05-9. Molecular formula: C27H42N2O14. Mole weight: 618.26. Purity: 95%+. Product ID: ACM2055033059. Alfa Chemistry ISO 9001:2015 Certified.
Methyltetrazine-PEG4-maleimide
Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802908-02-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-141278.
mPEG20K-MAL
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: mPEG-MAL, Methoxy-PEG-Maleimide. Molecular formula: average Mn 20000.
mPEG2K-MAL
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: mPEG-MAL, Methoxy-PEG-Maleimide. Molecular formula: average Mn 2000.
mPEG40K-MAL
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: mPEG-MAL, Methoxy-PEG-Maleimide. Molecular formula: average Mn 40000.
Multi-arm PEG-maleimide
four-arm branched poly(ethylene glycol) derivatives with maleimide function for conjugation. CAS No. Product ID: 7-00236. Molecular formula: Mole weight: Mw 10,000 Da.
N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5
N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5. Uses: Designed for use in research and industrial production. Product Category: Cyanine Fluorophores. CAS No. 2107273-74-3. Molecular formula: C50H68ClN7O10. Mole weight: 962.6. Purity: 0.9. IUPACName: 3-[2-[2-[2-[2-[2-[(1E,3E)-5-[1-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-3,3-dimethylindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]propanamide;chloride. Canonical SMILES: CC1(C2=CC=CC=C2[N+](=C1/C=C/C=C/C=C3C(C4=CC=CC=C4N3CCOCCOCCOCCN=[N+]=[N-])(C)C)CCOCCOCCOCCOCCC(=O)NCCN5C(=O)C=CC5=O)C.[Cl-]. Product ID: ACM2107273743-1. Alfa Chemistry ISO 9001:2015 Certified.
N-(m-PEG4)-N'-(PEG3-Mal)-Cy5
N-(m-PEG4)-N'-(PEG3-Mal)-Cy5 is a cyanine5 dye linker containing a PEG4 chain and a PEG3-Mal chain. The cyanine5 has an excitation/emission wavelength of 646/662 nm. The maleimide group can react with thiol groups from pH 6.5 to 7.5. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media. The water solubility properties of the PEG linker are enhanced with longer PEG chains. Uses: For industrial and laboratory use. Product Category: Fluorescein Dyes. CAS No. 2839527-02-3. Molecular formula: C49H67ClN4O10. Mole weight: 907.6 g/mol. Purity: 0.98. Product ID: DYE-FLU-0054. Alfa Chemistry ISO 9001:2015 Certified.
Stearic acid PEG Maleimide-2000 Da
Stearic acid is an 18 carbon saturated fatty acid lipid with excellent hydrophobicity. PEG modified stearic acid is an excellent amphilphilic polymer with both hydrophilicity and hydrophobility. Pegylated lipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides. Product ID: PE-0033. Mole weight: 2000 Da. Category: Emulsifier Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Semi-solid Dosage Form; Suppository Bases;Micro-drug Delivery Systems; Emulsifier Excipients; Stearic acid PEG Maleimide-2000 Da; PE-0033. Appearance: Off-white/white solid or viscous liquid depends on molecule weight. Solubility: Soluble in regular aqeous solution as well as most organic solvents. Storage: Store at -20°C, dessiccate. Protect from light. Avoid frequent thaw and freeze.
Stearic acid PEG Maleimide-3400 Da
Stearic acid is an 18 carbon saturated fatty acid lipid with excellent hydrophobicity. PEG modified stearic acid is an excellent amphilphilic polymer with both hydrophilicity and hydrophobility. Pegylated lipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides. Product ID: PE-0034. Mole weight: 3400 Da. Category: Emulsifier Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Semi-solid Dosage Form; Suppository Bases;Micro-drug Delivery Systems; Emulsifier Excipients; Stearic acid PEG Maleimide-3400 Da; PE-0034. Appearance: Off-white/white solid or viscous liquid depends on molecule weight. Solubility: Soluble in regular aqeous solution as well as most organic solvents. Storage: Store at -20°C, dessiccate. Protect from light. Avoid frequent thaw and freeze.
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809356-72-6. Pack Sizes: 5 mg. Product ID: HY-151696.
Y-PEG40K-MAL
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: Y-PEG-MAL. Molecular formula: average Mn 40000.
2,5,8,11,14,17-Hexaoxaoctadecane
2,5,8,11,14,17-Hexaoxaoctadecane, a derivative of polyethylene glycol (PEG), has become a ubiquitous solubilizer and carrier in the biomedicine industry. Widely utilized for its efficacy in drug delivery, it facilitates the targeted treatment of malignant neoplasms, HIV, and neurodegenerative diseases such as Alzheimer's, amongst others. Its implications continue to yield promising results in the field of contemporary medical research. Synonyms: Pentaethyleneglycol dimethyl ether; 1,14-dimethoxy-3,6,9,12-tetraoxa-tetradecane; NSC 244990; 1,2-bis-[2-2-Methoxy-ethoxy-ethoxy]-ethane; O,O'-Dimethyl-pentaethylene glycol; Pentaglyme. Grades: 95%. CAS No. 1191-87-3. Molecular formula: C12H26O6. Mole weight: 266.33.
D-Glc(Ac4)-beta-PEG(3)-N3
D-Glc(Ac4)-beta-PEG(3)-N3, an indispensable tool hailing from the biomedical realm, finds its purpose predominantly in the pharmaceutical industry. It is extensively employed for the purposeful administration of medications, ensuring their efficacy against particular ailments. The inclusion of polyethylene glycol (PEG) in D-Glc(Ac4)-beta-PEG(3)-N3 not only amplifies drug solubility but also guarantees stability and bioavailability. This agent's integration within drug delivery systems serves as a catalyst, augmenting the treatment of diverse maladies. Molecular formula: C20H31N3O12. Mole weight: 505.47.
Farletuzumab ecteribulin
Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORAb-202. CAS No. 2407465-18-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99612.
Firtecan pegol
Firtecan pegol, also known as EZN-2208,Pegylated SN-38, or PEG-SN38, is a water-soluble polyethyleneglycol-SN38 conjugate. In vitro, the IC50 of EZN-2208 ranged from 3-24 nM, which was 30- to 45-fold lower than CPT-11 or 2.5- to 3.5-fold higher than SN38. In both an early-disease Raji model and an advanced-disease Daudi model, treatment with multiple doses of EZN-2208 resulted in 90% and 100% cures of animals, respectively (cure defined as no sign of tumors by gross observations at the termination of study). The activity of EZN-2208 was dramatically superior to that of CPT-11 in all three models. The excellent therapeutic efficacy of EZN-2208 in several B-cell NHL xenograft models merits its evaluation in the clinic for lymphoid malignancies. Synonyms: EZN-2208 (Pegylated SN-38). PEG-SN38, Firtecan pegol. CAS No. 946062-05-1. Molecular formula: C118H122N12O37. Mole weight: 2300.321.
Methoxypoly(ethylene glycol) maleimide
for immobilization, water insoluble version of 7-00246. CAS No. Product ID: 7-00244. Molecular formula: MeO-PEG-maleimide. Mole weight: Mw 10,000. Purity: Activity > 60%, Polydispersity<1.05, Pyrogen Free. Properties: