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| Product | Description | |
|---|---|---|
| Malformin C | Malformin C is a fungal cyclic pentapeptide with antibacterial and anticancer activities. Study shows that Malformin C inhibits cell growth in Colon 38 and HCT 116 cells in a dose-dependent manner with IC50 of 0.27±0.07μM and 0.18±0.023μM, respectively. Synonyms: Malformin B1b; Cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl)? Cyclic (1?2)?-Disulfide; (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-]. Grades: ≥95%. CAS No. 59926-78-2. Molecular formula: C23H39N5O5S2. Mole weight: 529.72. |  |
| Malformin C | Peptide antibiotic. Induces root curvature and malformation in plants. Antibacterial, antimalarial and antitrypanosomal. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents.Malformin C is a bicyclic pentapeptide containing L-leucine, D-isoleucine, L-valine, and two D-cysteines coupled with a disulfide-bond bridge. Malformins A1 and C, originally isolated from the culture broth of Aspergillus niger FKI-2342, were found to abrogate the bleomycin-induced G2 arrest in Jurkat cells with IC50 values of 480nM and 0.9nM, respectively. Malformins may be promising candidates as anti-cancer agents. Source:Synthetic. Originally isolated from Aspergillus niger FKI-2342. Group: Biochemicals. Grades: Highly Purified. CAS No. 59926-78-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C23H39N5O5S2. US Biological Life Sciences. |  Worldwide |
| Malformin A1 | Peptide antibiotic. Antibcaterial. Plant growth stimulator. Induces root curvature and malformation in plants. Mycotoxin. Prevents interleukin-1 (IL-1) induced endothelial changes by inhibition of protein synthesis. Inhibitor of interleukin-1 beta (IL1 beta) binding to its receptor. Enhancer of cellular fibrinolytic activity. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents. Anticancer compound. Cytotoxic against several cancer cell lines. Antimalarial and antitrypanosomal. Inhibitor of BRAF-mutated melanoma cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 3022-92-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C??H??N?O?S?. US Biological Life Sciences. | Worldwide |
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