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| Product | Description | |
|---|---|---|
| Matrine | Matrine. Group: Biochemicals. Alternative Names: Sophoridine. Grades: Plant Grade. CAS No. 519-02-8. Pack Sizes: 20mg. Molecular Formula: C15H24N2O, Molecular Weight: 248.364. US Biological Life Sciences. |  Worldwide |
| Matrine | Matrine is an alkaloid found in plants of the Sophora genus. The compound is an antioxidant with anti-tumoral properties and has neuroprotective effects in rodent models for Parkinson's disease. It inhibits inflammatory responses and was shown to attenuates collagen-induced arthritis in mice. Moreover, matrine can attenuate cardiac fibrosis and hepatitis B-induced liver damage. The compound can also agonise opioid receptors and has anti-nociceptive properties. Group: Other alkaloids. Alternative Names: Ex Sophporae Radix. CAS No. 519-02-8. Molecular formula: C15H24N2O. Mole weight: 248.36 g/mol. Appearance: White powder. Purity: 0.98. IUPACName: (1R, 2R, 9S, 17S)-7, 13-diazatetracyclo[7.7.1.02, 7.013, 17]heptadecan-6-one. Canonical SMILES: C1C[C@@H]2[C@H]3CCCN4[C@H]3[C@@H] (CCC4)CN2C (=O)C1. Density: 1.19 g/ml. Catalog: ACM519028-2. |  |
| Matrine | Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Matridin-15-one; Vegard; α-Matrine. CAS No. 519-02-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-N0164. |  |
| Allomatrine | Sourced from herbs of Sophora alopecuroides L. Either (+)-matrine or (+)-Allomatrine when given i.c.v. may stimulate the descending dynorphinergic neuron, resulting in the stimulation of KORs in the spinal cord, and this phenomenon in turn produces the antinociception in mice. Allomatrine is a natural compound used in cosmetics material. Uses: Inhibit the central nervous anti-inflammatory. Synonyms: 6-Allomatrine; Tetrahydroisosophoramine. Grades: >98%. CAS No. 641-39-4. Molecular formula: C15H24N2O. Mole weight: 248.36. |  |
| (+)-Matrine-d3 | (+)-Matrine-d3. Uses: For analytical and research use. Group: Phytochemicals; pharmaceutical toxicology. Pack Sizes: 10MG. Catalog: APS003582. Format: Neat. |  |
| Oxymatrine | Oxymatrine (matrine oxide, matrine N-oxide, matrine 1-oxide) is one of many quinolizidine alkaloid compounds extracted from the root of Sophora flavescens, a Chinese herb. It is very similar in structure to matrine, which has one less oxygen atom. Oxymatrine has a variety of effects in vitro and in animal models, including protection against apoptosis, tumor and fibrotic tissue development, and inflammation. Furthermore, oxymatrine has been shown to decrease cardiac ischemia (decreased blood perfusion), myocardial injury, arrhythmias (irregular heartbeats), and improve heart failure by increasing cardiac function. Group: Inhibitors. Alternative Names: Ammothamnine. CAS No. 16837-52-8. Molecular formula: C15H24N2O2. Mole weight: 264.36. Appearance: Solid. Purity: 98%+. Canonical SMILES: O=C1CCC[C@]2 ([H])[C@@]3 ([H])CCC[N@@+]4 ([O-])[C@@]3 ([H])[C@] (CCC4) ([H])CN21. ECNumber: 605-514-4. Catalog: ACM16837528. | |
| BI-6C9 | BI-6C9 ( N-[4-[(4-Aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-Butanamide) is a tBid inhibitor that possesses antiapoptotic properties. Bid plays an essential role in matrine-induced AIF translocation. BI-6C9 also blocked matrine-induced AIF translocation detected by confocal microscopy. Bid inhibitor BI-6C9 was applied to confirm the essential role of Bid in cell death induced by matrine. Synonyms: N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-butanamide. Grades: ≥98%. CAS No. 791835-21-7. Molecular formula: C23H25N3O4S2. Mole weight: 471.6. | |
| Kurarinone | Kurarinone is an orally active flavonoid isolated from matrine that inhibits the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting cell differentiation of Th1 and Th17. Kurarinone has antitumor and anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 34981-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N2279. | |
| Natural Product Derivatives Library | The library consists of more than 4, 000 members belonging 22 scaffolds (average 180 compounds per scaffold). - The library includes the following sub-libraries:- Cytisine-based sub-library- Matrine-based sub-library- Podophyllotoxin-based sub-library- Sub-library based on naturally occurring privileged BBS such ashydroxy-prolines, triptamine, nor-tropolone etc. - TargetMol "Beyond RO5" filters have been applied for the library population (See Phys-chem parameters for the library members). - NO Med-Chem restrictions (widely accepted and proprietary TargetMol substructure filters on reactive functionalities, toxicophoric, instability suspicions etc. ). - More than 90% purity for each library member confirmed by LC-MS or NMR analysis. Uses: Scientific use. Product Category: NY1000. Categories: Natural Product Derivatives Libraries. |  |
| Sophora Root Extract | Sophora root extract is prepared from the sophora flavescens, a species of plant in the genus sophora. Matrine is the major alkaloid component found in sophora root extract. Sophora root extract is commonly used for the treatment of viral hepatitis, enteritis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases. Group: Others. Mole weight: 248.37. Sophora Root Extract; Sophora Flavescens Alt. Cat No: EXTC-019. |  |
| YF-18 | YF-18 is a matrine derivative that has an inhibitory effect on lung cancer cells. Studies indicated that YF-18 induced G2/M cell cycle arrest and inhibited migration of lung cancer cells in a dose-dependent manner. In addition, it suppressed cell proliferation and migration through down-regulating Skp2 and up-regulating its substrates, p27 and E-cadherin. Uses: Anti-lung cancer. Synonyms: YF 18; YF18. | |
| matrilysin | Found in rat uterus; at 19 kDa, the smallest member of peptidase family M10 (interstitial collagenase family). Similar in specificity to stromelysin, but more active on azocoll. Group: Enzymes. Synonyms: matrin; uterine metalloendopeptidase; matrix metalloproteinase 7; putative (or punctuated) metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative metalloproteinase; MMP. Enzyme Commission Number: EC 3.4.24.23. CAS No. 141256-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4304; matrilysin; EC 3.4.24.23; 141256-52-2; matrin; uterine metalloendopeptidase; matrix metalloproteinase 7; putative (or punctuated) metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative metalloproteinase; MMP. Cat No: EXWM-4304. | |
| Matrix Metalloproteinase-7 from human, Recombinant | MMP-7 degrades general matrix components and may have a role in processes such as host defense, cell proliferation, and protein turnover as well as tissue remodeling. Group: Enzymes. Synonyms: MMP7; matrix metallopeptidase 7; MMP-7; matrin; uterine metalloendopeptidase; matrix metalloproteinase 7; putative (or punctuated) metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative metalloproteinase; MMP. CAS No. 141256-52-2. Matrix Metalloproteinase. Storage: -70°C. Form: buffered aqueous solution, Supplied in a buffer containing the active enzyme in 10 mM HEPES, pH 7.4, 0.15 M sodium chloride, 5 mM calcium chloride. Source: E. coli. Species: Human. MMP7; matrix metallopeptidase 7; MMP-7; matrin; uterine metalloendopeptidase; matrix metalloproteinase 7; putative (or punctuated) metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative metalloproteinase; MMP. Cat No: NATE-0451. | |
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