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| Product | Description | |
|---|---|---|
| matriptase | This trypsin-like integral-membrane serine peptidase has been implicated in breast cancer invasion and metastasis. The enzyme can activate hepatocyte growth factor/scattering factor (HGF/SF) by cleavage of the two-chain form at an Arg residue to give active α- and β-HGF, but It does not activate plasminogen, which shares high homology with HGF.The enzyme can also activate urokinase plasminogen activator (uPA), which initiates the matrix-degrading peptidase cascade. Belongs in peptidase family S1A. Group: Enzymes. Synonyms: serine protease 14; membrane-type serine protease 1; MT-SP1; prostamin; serine protease TADG-15; tumor-associated differentially-expressed gene 15 protein; ST14; breast cancer 80 kDa protease; epithin; serine endopeptidase SNC19. Enzyme Commission Number: EC 3.4.21.109. CAS No. 241475-96-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4104; matriptase; EC 3.4.21.109; 241475-96-7; serine protease 14; membrane-type serine protease 1; MT-SP1; prostamin; serine protease TADG-15; tumor-associated differentially-expressed gene 15 protein; ST14; breast cancer 80 kDa protease; epithin; serine endopeptidase SNC19. Cat No: EXWM-4104. |  |
| Matriptase-2 from Human, Recombinant | Matriptase-2 (TMPRSS6) is a type II transmembrane serine protease mainly produced by the liver. It acts as a potent negative regulator of hepcidin, a hepatic peptide hormone and integral player in regulating iron homeostasis. Group: Enzymes. Synonyms: Transmembrane protease serine 6; TMPRSS6; Matriptase-2. Enzyme Commission Number: EC 3.4.21.-. Purity: Purified by multi-step chromatography. Matriptase-2. Mole weight: ~84 kDa; a-subunit: ~56kDa; b-subunit: ~28kDa. Activity: ~2.5U/ul. Stability: Stable for at least 6 months when stored at -20°C. Recommended Assay Buffer: 100mM TRIS, pH 9.0, containing 0.5mg/ml BSA. Do not store diluted solutions. Storage: Short Term Storage: -20°C; Long Term Storage: -80°C. Form: Liquid. In 100mM TRIS-HCl, pH 9.0, containing 150 mM sodium chloride and 20% glycerol. Source: Drosophila Schneider 2 (S2) cells. Species: Human. Transmembrane protease serine 6; TMPRSS6; Matriptase-2. Cat No: NATE-0857. | |
| Matriptase-IN-2 | Matriptase-IN-2 (compound 432) is a potent Matriptase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1268874-09-4. Pack Sizes: 5 mg. Product ID: HY-W783268A. |  |
| Boc-Gln-Ala-Arg-pNA | Boc-Gln-Ala-Arg-pNA is a chromogenic substrate for trypsin and matriptase-2. Synonyms: Boc-QAR-pNA; L-Argininamide, N2-[(1,1-dimethylethoxy)carbonyl]-L-glutaminyl-L-alanyl-N-(4-nitrophenyl)-; N2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-glutaminyl-L-alanyl-N-(4-nitrophenyl)-L-argininamide; N-Boc-Gln-Ala-Arg-p-nitroanilide. Grade: ≥95% by HPLC. CAS No. 1926163-47-4. Molecular formula: C25H39N9O8. Mole weight: 593.63. |  |
| Camostat mesylate | Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2 , shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Camostat mesilate; FOY305; FOY-S980. CAS No. 59721-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13512. | |
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