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(3-Mercaptopropyl) methyldimethoxysilane. Group: Biochemicals. Grades: Highly Purified. CAS No. 31001-77-1. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C6H16O2SSi. US Biological Life Sciences.
Worldwide
3-Mercaptopropylmethyldimethoxysilane
It can improves the adhesion of polysulfide and polyurethane sealants to glass and metal surfaces, improve low-rolling resistance in silica-reinforced tire tread compounds, and enhance properties in mineral-reinforced articles such as shoe soles, rubber goods. Uses: It can be used as coupling agent to improve the adhesion of sulfur cured elastomers (polysulfide, polyurethane sealants) to inorganic fillers (such as silica, clay, glass, mica and talc etc.), fiberglass and surfaces. mineral-reinforced articles such as shoe soles, rubber rollers and wheels, white sidewalls, and wire and cable insulation also can be produced with lower silane loadings. Group: Heterocyclic organic compound. Alternative Names: 3-Mercaptopropylmethyldimethoxysilane. CAS No. 31001-77-1. Molecular formula: C6H16O2SSi. Mole weight: 180.34 g/mol. Appearance: Transparent to rice yellow liquid. Purity: 0.98. IUPACName: dimethoxymethyl(3-sulfanylpropyl)silicon. Canonical SMILES: CO[Si](C)(CCCS)OC. Density: 1.00±0.010 g/mL. Catalog: ACM31001771.
(3-Mercaptopropyl)Methyldimethoxysilane
It is an intermediate useful for synthesis of silicone fluids with mercaptopropyl functionality. These types of silicones can be used in thiol-ene UV cure systems. Group: Salt. Alternative Names: 3-(Dimethoxymethylsilyl)-1-propanethiol. CAS No. 31001-77-1. Pack Sizes: It is supplied in 5-gallon (40 lbs.) pails and 55-gallon (440 lbs.) drums. Moisture Sensitive - maintain under nitrogen. Product ID: 3-[dimethoxy(methyl)silyl]propane-1-thiol. Molecular formula: 180.34 g/mol. Mole weight: C6H16O2SSi. CO[Si](C)(CCCS)OC. InChI=1S/C6H16O2SSi/c1-7-10(3, 8-2)6-4-5-9/h9H, 4-6H2, 1-3H3. IKYAJDOSWUATPI-UHFFFAOYSA-N. 0.95.
(3-Mercaptopropyl)Triethoxysilane
Liquid. Group: Saltsilane coupling agentsself assembly and contact printing materials. Alternative Names: 3-(Triethoxysilyl)propanethiol. CAS No. 14814-09-6. Molecular formula: C9H22O3SSi. Mole weight: 238.42 g/mol. Appearance: Colorless to almost colorless clear liquid. Purity: >96%. IUPACName: 3-triethoxysilylpropane-1-thiol. Canonical SMILES: CCO[Si](CCCS)(OCC)OCC. ECNumber: 238-883-1. Catalog: ACM14814096.
Siloxanes and Silicones, di-Me, polymers with 3-mercaptopropyl silsesquioxanes
Siloxanes and Silicones, di-Me, polymers with 3-mercaptopropyl silsesquioxanes. CAS No. 108775-26-4. Catalog: ACM108775264.
2-MPPA
2-MPPA is a selective glutamate carboxypeptidase II (GCP II) inhibitor (IC50 = 90 nM), which is selective for GCP II over NMDA, kainate and AMPA glutamate receptors and MMP-1, -2, -3, -7, -9, ACE and NEP metalloproteases. 2-MPPA can be used in the treatment of neurological disorders associated with excessive activation of glutamatergic systems. Attenuates glutamate transmission resulting in the relief of neuropathic pain. This compound has neuroprotective properties. Synonyms: 2-(3-Mercaptopropyl)pentanedioic acid; 2-MPPA; 2 MPPA; 2MPPA. CAS No. 254737-29-6. Molecular formula: C8H14O4S. Mole weight: 206.26.
3-Amino-1-propanethiol hydrochloride
3-Amino-1-propanethiol hydrochloride (CAS# 7211-54-3 ) is a useful research chemical. Synonyms: 3-aminopropane-1-thiol hydrochloride; (3-Mercaptopropyl)ammonium chloride; Homocysteamine hydrochloride; 3-aminopropane-1-thiol HCl. Grades: > 98 %. CAS No. 7211-54-3. Molecular formula: C3H10ClNS. Mole weight: 127.64.
Bendamustine Impurity 38
Bendamustine Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-hydroxy-3-mercaptopropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate. Molecular Formula: C19H27Cl2N3O3S. Mole Weight: 448.41. Catalog: APB01302.
BIM-46050
BIM-46050 is a novel and potent inhibitor of human farnesyltransferase. Synonyms: BIM46050; BIM 46050; (S)-2-((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carboxamido)-4-(methylthio)butanoic acid. Grades: >98%. CAS No. 201487-52-7. Molecular formula: C14H12N6O. Mole weight: 480.75.
BIM-46068
BIM-46068 is a novel and potent inhibitor of human farnesyltransferase. Synonyms: BIM 46068; BIM46068; (S)-methyl 2-((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carboxamido)-4-(methylthio)butanoate. Grades: >98%. CAS No. 201487-53-8. Molecular formula: C17H28ClNO2. Mole weight: 494.77.
Erdosteine Thioacid Disodium Salt
Erdosteine Thioacid Disodium Salt is the active metabolite of Erdosteine, which is a mucolytic used in the treatment of excessive viscous mucus. Synonyms: N-[[ (Carboxymethyl) thio]acetyl]homocysteine Disodium Salt; [[2-Oxo-2-[ (1-carboxy-3-mercaptopropyl) amino]ethyl]thio]acetic acid Disodium Salt; Erdosteine Metabolite 1 Disodium Salt; Butanoic acid, 2-((((carboxymethyl)thio)acetyl)amino)-4-mercapto-, DL-, sodium salt (1:2); DL-2-((((Carboxymethyl)thio)acetyl)amino)-4-mercaptobutanoic acid Disodium Salt. Grades: 96%. CAS No. 254884-18-9. Molecular formula: C8H11NNa2O5S2. Mole weight: 311.29.
FTase Inhibitor I
FTase inhibitor I is a potent and selective farnesyltransferase (FTase) inhibitor with an IC50 of 21 nM, which is 30-fold higher for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). Synonyms: Farnesyltransferase Inhibitor I; B581; N-[(2S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylbutyl]-L-phenylalanyl-L-methionine. Grades: ≥95%. CAS No. 149759-96-6. Molecular formula: C22H38N4O3S2. Mole weight: 470.69.
FTI-249
FTI-249 is a Farnesyltransferase inhibitor, which potently inhibited FTase (IC50 = 100-200 nM). Synonyms: FTI 249; FTI249; (S)-2-(4-(((R)-2-amino-3-mercaptopropyl)amino)benzamido)-4-(methylthio)butanoic acid. Grades: 98%. CAS No. 161721-65-9. Molecular formula: C15H23N3O3S2. Mole weight: 357.49.
FTI-276
FTI-276 is a potent and selective farnesyltransferase inhibitor, which is also a tetrapeptide mimetic of the carboxyl terminus of K-Ras4B. FTI-276 blocked the growth in nude mice of a human lung carcinoma that expresses the two most prevalent genetic alterations in human cancers (K-Ras oncogenic mutation and deletion in the tumor suppressor gene p53). In contrast, FTI-276 did not inhibit tumor growth of a human lung carcinoma that harbors no Ras mutations. Furthermore, FTI-276 inhibited oncogenic signaling and tumor growth of NIH 3T3 cells transformed with the ras but not the raf oncogene. Synonyms: FTI276; FTI 276; (S)-2-(5-(((R)-2-amino-3-mercaptopropyl)amino)-[1,1'-biphenyl]-2-ylcarboxamido)-4-(methylthio)butanoic acid. CAS No. 170006-72-1. Molecular formula: C21H27N3O3S2. Mole weight: 433.59.
FTI 276 trifluoroacetate salt
FTI 276 is a Ras CAAX peptidomimetic, a selective inhibitor of farnesyltransferase (FTase) with > 100-fold selectivity over geranylgeranyltransferase I (GGTase I) (IC50 = 0.5 and 50 nM, respectively). It exhibits an inhibitory effect on growth of human lung carcinoma expressing oncogenic K-Ras in nude mice. Synonyms: FTI 276 trifluoroacetate salt; FTI276 trifluoroacetate salt; FTI-276 trifluoroacetate salt; N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine trifluoroacetate salt. Grades: ≥95% by HPLC. CAS No. 1217471-51-6. Molecular formula: C21H27N3O3S2.C2HF3O2. Mole weight: 547.61.
FTI 277 trifluoroacetate salt
FTI 277 is a prodrug form of FTI 276 that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM) with antiproliferative activity. It potently inhibits H-Ras and K-Ras processing in whole cells (IC50 = 0.1 and 10 μM, respectively) and disrupts constitutive H-Ras-specific activation of MAPK. Synonyms: FTI 277 trifluoroacetate salt; FTI277 trifluoroacetate salt; FTI-277 trifluoroacetate salt; N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt. Grades: ≥95% by HPLC. CAS No. 1217447-06-7. Molecular formula: C22H29N3O3S2.C2HF3O2. Mole weight: 561.64.
GGTI 286 trifluoroacetate salt
GGTI 286 is a cell permeable and potent inhibitor of geranylgeranyltransferase I (GGTase I) that selectively inhibits geranylgeranylation of Rap1A over farnesylation of H-Ras in NIH3T3 cells (IC50s = 2 and >30 μM, respectively). Synonyms: N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-leucine, methyl ester, trifluoroacetate salt. Grades: ≥90%. Molecular formula: C23H31N3O3S·2CF3COOH. Mole weight: 657.62.
GGTI-298
GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-298 causes G0-G1 cell cycle block and apoptosis in A549 cells (IC50 = 10 μM for A549 cells) and inhibits cell invasion and migration in COLO 320CM cells. Synonyms: methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate; GGTI 298; GGTI298; GGTI-298; N-4-[2(R)-Amino-3-mercaptopropyl]amino-2-naphthylbenzoyl-(L)-Leucine methyl ester, TFA; (S)-methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate. CAS No. 180977-44-0. Molecular formula: C27H33N3O3S. Mole weight: 479.63.
GGTI 298 (trifluoroacetate salt)
GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-298 causes G0-G1 cell cycle block and apoptosis in A549 cells (IC50 = 10 μM for A549 cells) and inhibits cell invasion and migration in COLO 320CM cells. Synonyms: methyl (4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzoyl)-L-leucinate 2,2,2-trifluoroacetate; GGTI-298 TFA; GGTI-298 trifluoride salt; GGTI-298; GGTI 298; GGTI298. CAS No. 1217457-86-7. Molecular formula: C27H33N3O3S.CF3COOH. Mole weight: 593.7.
L-744832
L-744832, also known as L-744,832, is a potent Farnesyltransferase inhibitor with potential anticancer activity. Synonyms: L 744832; L744832; (2S)-2-[[2-[(2S,3S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylpentoxy]-1-oxo-3-phenylpropyl]amino]-4-methylsulfonylbutanoic acid propan-2-yl ester. CAS No. 160141-09-3. Molecular formula: C26H45N3O6S2. Mole weight: 559.78.