Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Mertansine | Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM1; Maytansinoid DM1. CAS No. 139504-50-0. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19792. |  |
| Mertansine | Mertansine Inhibitor. Uses: Scientific use. Product Category: T1992. CAS No. 139504-50-0. |  |
| Mertansine | Mertansine is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. Group: Biochemicals. Grades: Highly Purified. CAS No. 139504-50-0. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C35H48ClN3O10S. US Biological Life Sciences. |  Worldwide |
| Mertansine | Mertansine, the cytotoxic component in antibody-drug conjugates, is attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker or SMCC (4-(3-mercapto-2,5-dioxo-1 pyrrolidinylmethyl)-cylohexanecarboxylic acid) linkerto create an antibody-drug conjugate. It derives from a maytansine. Synonyms: (14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(3-mercaptopropanoyl)-N-methyl-L-alaninate; N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine; DM 1; Maytansinoid DM 1; N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine; DM-1; DM1; DM1 Compound; DM1 [Maytansinoid]. Grade: ≥95%. CAS No. 139504-50-0. Molecular formula: C35H48ClN3O10S. Mole weight: 738.29. |  |
| cantuzumab mertansine | Cantuzumab mertansine (SB-408075; huC242-DM1), an ADC, is an immunoconjugate of the potent maytansine derivative (DM1; HY-19792) and the humanized monoclonal antibody (huC242) directed to CanAg. Cantuzumab mertansine has cytotoxic toward colon cancer cells and has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts. Uses: Designed for use in research and industrial production. Additional or Alternative Names: cantuzumab mertansine. Product Category: Inhibitors. CAS No. 400010-39-1. Canonical SMILES: [Cantuzumab mertansine]. Product ID: ACM400010391. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Cantuzumab mertansine | Cantuzumab mertansine (SB-408075; huC242-DM1), an ADC , is an immunoconjugate of the potent maytansine derivative ( DM1 ; HY-19792) and the humanized monoclonal antibody (huC242) directed to CanAg. Cantuzumab mertansine has cytotoxic toward colon cancer cells and has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SB-408075; huC242-DM1. CAS No. 400010-39-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99492. | |
| DM1-SMe | DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Synonyms: DM1-SMe; DM1-SSMe; maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative; N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine. Grade: ≥98%. CAS No. 138148-68-2. Molecular formula: C36H50ClN3O10S2. Mole weight: 784.38. | |
| DM1-SMe | DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Uses: Designed for use in research and industrial production. Additional or Alternative Names: DM1-SMe; DM1-SSMe; SMe-DM4,; maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative; N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 138148-68-2. Molecular formula: C36H50ClN3O10S2. Mole weight: 784.38. Purity: >98%. IUPACName: N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine. Canonical SMILES: C[C@@H]1[C@@H]2C[C@](NC(O2)=O)(O)[C@H](OC)/C=C\C=C(C)\CC3=CC(N(C)C(C[C@@H](OC([C@@H](N(C(CCSSC)=O)C)C)=O)[C@@]4(C)C1O4)=O)=C(Cl)C(OC)=C3. Product ID: ACM138148682. Alfa Chemistry ISO 9001:2015 Certified. Categories: DMS metro station. | |
| Lorvotuzumab | Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds CD56 (NCAM1). Lorvotuzumab can be used to synthesize an ADC compound, Lorvotuzumab mertansine [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-NCAM1/ CD56 Reference Antibody (lorvotuzumab). CAS No. 339306-30-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99372. | |
| N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine | N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine. Group: Biochemicals. Alternative Names: Mertansine, DM 1; Maytansinoid DM 1. Grades: Highly Purified. CAS No. 139504-50-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C35H48ClN3O10S. US Biological Life Sciences. | Worldwide |
| SMCC-DM1 | SMCC-DM1 is a mertansine drug (DM1) with a reactive linker SMCC to make antibody drug conjugate. DM1 (mertansine), a thiol-containing maytansinoid, is a potent microtubule-disrupting agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1228105-51-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C51H66ClN5O16S, Molecular Weight: 1072.60999999999. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
