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| Product | Description | |
|---|---|---|
| 2- (2- ( (t-Butyldimethylsilyl) methoxy) ethyl) -5- (2- ( (tert-butyldimethylsilyl) oxy) ethyl) pyrazine | 2- (2- ( (t-Butyldimethylsilyl) methoxy) ethyl) -5- (2- ( (tert-butyldimethylsilyl) oxy) ethyl) pyrazine is an intermediate in synthesizing 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340), which is a degradation product of Clavulanic Acid (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C20H40N2O2Si2. US Biological Life Sciences. |  Worldwide |
| 2- (2- ( (t-Butyldimethylsilyl) methoxy) ethyl) -5- (2- ( (tert-butyldimethylsilyl) oxy) ethyl) pyrazine N-Oxide | 2- (2- ( (t-Butyldimethylsilyl) methoxy) ethyl) -5- (2- ( (tert-butyldimethylsilyl) oxy) ethyl) pyrazine N-Oxide is an intermediate in synthesizing 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340), which is a degradation product of Clavulanic Acid (C563750), a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H42N2O3Si2. US Biological Life Sciences. | Worldwide |
| (2S, 5R) -2, 5-Dihydro-3, 6-dimethoxy-2-[ (2S) -2-[[4-methoxy-3- (3-methoxypropoxy) phenyl]methyl]-3-methylbutyl]-5- (1-methylethyl) pyrazine | (2S, 5R) -2, 5-Dihydro-3, 6-dimethoxy-2-[ (2S) -2-[[4-methoxy-3- (3-methoxypropoxy) phenyl]methyl]-3-methylbutyl]-5- (1-methylethyl) pyrazine. Group: Biochemicals. Grades: Highly Purified. CAS No. 656241-17-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C26H42N2O5. US Biological Life Sciences. | Worldwide |
| 5-Chloro-N-methoxy-N-methyl-2-pyrazinecarboxamide | Used in the preparation of spirocyclic compounds for the treatment of bacterial infections. Group: Biochemicals. Grades: Highly Purified. CAS No. 1211533-01-5. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 6-ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide | 6-ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide. Uses: Designed for use in research and industrial production. Product Category: Pyrazines. Appearance: White Powder. CAS No. 1254053-43-4. Molecular formula: C29H44N8O3. Mole weight: 552.7. Purity: 0.95. Product ID: ACM1254053434. Alfa Chemistry ISO 9001:2015 Certified. Categories: Gilteritinib. |  |
| Methoxy-2 3-Methyl Pyrazine | Methoxy-2 3-Methyl Pyrazine. CAS No. 2847-30-5. FEMA No. 3183. Kosher: Y. VIGON Item # 500616. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Pyrazine,2-methoxy-5-methyl- | Pyrazine,2-methoxy-5-methyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-methoxy-5-methylpyrazine;Pyrazine, 2-methoxy-5-methyl-;METHOXY-3-METHYLPYRAZINE. Product Category: Heterocyclic Organic Compound. CAS No. 2882-22-6. Molecular formula: C6H8N2O. Mole weight: 124.14052. Product ID: ACM2882226. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pyrazine, 3-methoxy-2-methyl-5-(1-methylethyl)- (9CI) | Pyrazine, 3-methoxy-2-methyl-5-(1-methylethyl)- (9CI). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pyrazine, 3-methoxy-2-methyl-5-(1-methylethyl)- (9CI). Product Category: Heterocyclic Organic Compound. CAS No. 245757-84-0. Molecular formula: C9H14N2O. Mole weight: 166.22026. Product ID: ACM245757840. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5-isopropyl-3-methoxy-2-methylpyrazine. | |
| 2-Isobutyl-3-methoxypyrazine-[d3] | 2-Isobutyl-3-methoxypyrazine-[d3]. Synonyms: D3-2-Isobutyl-3-methoxypyrazine; 2-Isobutyl-3-methoxy-d3-pyrazine; 2-(Methoxy-d3)-3-(2-methylpropyl)pyrazine; 3-Isobutyl-2-methoxypyrazine-d3; 2-Methoxy-3-isobutylpyrazine-d3. Grade: 98%; 99% atom D. CAS No. 588732-63-2. Molecular formula: C9H11D3N2O. |  |
| 2-Isopropyl-3-methoxypyrazine-[d3] | 2-Isopropyl-3-methoxypyrazine-[d3]. Synonyms: 2-Isopropyl-3-methoxy-d3-pyrazine; 2-(Methoxy-d3)?-3-(1-methylethyl)?pyrazine; 2-methoxy-3-propan-2-ylpyrazine-d3; 3-isopropyl-2-methoxypyrazine-d3; Isopropyl methoxy pyrazine-d3; Isopropylmethoxypyrazine-d3. Grade: 98%; 99% atom D. CAS No. 588732-60-9. Molecular formula: C8H9D3N2O. Mole weight: 155.21. | |
| 2-sec-Butyl-3-methoxypyrazine | A compound contents in musts and wines from Vitis vinifera variety Cabernet Sauvignon. Group: Biochemicals. Alternative Names: 2-Methoxy-3-(1-methylpropyl)pyrazine; 2-Methoxy-3-sec-butylpyrazine; 3-sec-Butyl-2-methoxypyrazine. Grades: Highly Purified. CAS No. 24168-70-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Bevenopran | Bevenopran is a peripherally selective μ- and δ-opioid receptor antagonist. It is used for the treatment of chronic opioid-induced constipation. It was developed by Cubist Pharmaceuticals and was in clinical phase 3 trial, but now it is terminated. Uses: Bevenopran is used for the treatment of chronic opioid-induced constipation. Synonyms: 5-(2-Methoxy-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)pyrazine-2-carboxamide; CB-5945, CB5945, CB 5945, ADL-5945, ADL5945, ADL 5945, MK2402, MK 2402, MK-2402,OpRA III; Bevenopran. Grade: 98%. CAS No. 676500-67-7. Molecular formula: C20H26N4O4. Mole weight: 386.45. | |
| CCT244747 | CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inhibitor with potential anticancer activity. CCT244747 inhibited cellular CHK1 activity (IC(50) 29-170 nmol/L), significantly enhanced the cytotoxicity of several anticancer drugs, and abrogated drug-induced S and G(2) arrest in multiple tumor cell lines. CCT244747 represents the first structural disclosure of a highly selective, orally active CHK1 inhibitor and warrants further evaluation alone or combined with genotoxic anticancer therapies. Synonyms: CCT-244747; CCT 244747; 3-{[(2R)-1-(Dimethylamino)-2-propanyl]oxy}-5-{[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino}-2-pyrazinecarbonitrile; 3-[(1R)-2-(Dimethylamino)-1-methylethoxy]-5-[[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino]-2-pyrazinecarbonitrile; (R)-3-((1-(dimethylamino)propan-2-yl)oxy)-5-((4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl)amino)pyrazine-2-carbonitrile. Grade: ≥98%. CAS No. 1404095-34-6. Molecular formula: C20H24N8O2. Mole weight: 408.46. | |
| Evixapodlin | Evixapodlin is a human programmed cell death ligand 1 (PD-1/PD-L1) protein/protein interaction inhibitor with an IC50 of 0.213 nM. It has anticancer and antiviral functions. Synonyms: (12S,122S)-62,72-dichloro-53,86-dimethoxy-3,10-diaza-5,8(2,5)-dipyrazina-1,12(2)-dipyrrolidina-6,7(1,3)-dibenzenadodecaphane-15,125-dione; (5S,5'S)-5,5'-((((5,5'-(2,2'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one); 2-Pyrrolidinone, 5,5'-[(2,2'-dichloro[1,1'-biphenyl]-3,3'-diyl)bis[(3-methoxy-5,2-pyrazinediyl)methyleneiminomethylene]]bis-, (5S,5'S)-; PD-1/PD-L1-IN 7. Grade: ≥98%. CAS No. 2374856-75-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61. | |
| Gilteritinib | Gilteritinib, also known as (ASP2215, is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations. In invitro, among the 78 tyrosine kinases tested, ASP2215 inhibited FLT3, LTK, ALK, and AXL kinases by over 50% at 1 nM with an IC50 value of 0.29 nM for FLT3, approximately 800-fold more potent than for c-KIT, the inhibition of which is linked to a potential risk of myelosuppression. ASP2215 inhibited the growth of MV4-11 cells, which harbor FLT3-ITD, with an IC50 value of 0.92 nM, accompanied with inhibition of pFLT3, pAKT, pSTAT5, pERK, and pS6. ASP2215 decreased tumor burden in bone marrow and prolonged the survival of mice intravenously transplanted with MV4-11 cells. ASP2215 may have potential use in treating AML. Synonyms: ASP2215; ASP-2215; ASP 2215; Xospata; Gilteritinibum; 6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide; 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide. Grade: ≥95%. CAS No. 1254053-43-4. Molecular formula: C29H44N8O3. Mole weight: 552.71. | |
| Gilteritinib hemifumarate | Gilteritinib hemifumarate is a medication used to treat acute myeloid leukemia (AML), particularly in patients with specific genetic mutations in the FLT3 gene (FMS-like tyrosine kinase 3). Gilteritinib is a tyrosine kinase inhibitor that specifically targets and inhibits the FLT3 receptor, which is often mutated and overactive in certain types of AML. By inhibiting FLT3, gilteritinib helps to reduce the proliferation of leukemia cells. Synonyms: Gilteritinib fumarate; ASP-2215 hemifumarate; 2-Pyrazinecarboxamide, 6-ethyl-3-((3-methoxy-4-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)-, (2E)-2-butenedioate (2:1); 6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide hemifumarate. Grade: ≥95%. CAS No. 1254053-84-3. Molecular formula: C29H44N8O3.1/2C4H4O4. Mole weight: 1221.52. | |
| Spirotryprostatin A | Spirotryprostatin A is an indole alkaloid found in Aspergillus fumigatus fungus, which exhibits anti-mitotic activity. Synonyms: Spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]-2',5,10(1'H)-trione, 1,5a,6,7,8,10a-hexahydro-6'-methoxy-3-(2-methyl-1-propenyl)-, (2S,3S,5aS,10aS)-; (2S,3S,5aS,10aS)-1,5a,6,7,8,10a-Hexahydro-6'-methoxy-3-(2-methyl-1-propen-1-yl)spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]-2',5,10(1'H)-trione; (-)-Spirotryprostatin A; (3S,3'S,5'aS,10'aS)-6-Methoxy-3'-(2-methylprop-1-enyl)spiro[1H-indole-3,2'-3,5a,6,7,8,10a-hexahydro-1H-dipyrrolo[1,2-c:1',4'-f]pyrazine]-2,5',10'-trione. Grade: 98.0%. CAS No. 182234-25-9. Molecular formula: C22H25N3O4. Mole weight: 395.45. | |
| Spirotryprostatin B | It is a mammalian cell cycle inhibitor produced by the strain of Aspergillus fumigatus. 12.5 μg/mL of Spirotryprostatin B can inhibit the G2/M phase of the cell cycle in tsFT210 cells. Synonyms: (3S,3'S,5'aS)-6-Methoxy-3'-(2-methylprop-1-enyl)spiro[1H-indole-3,2'-5a,6,7,8-tetrahydro-3H-dipyrrolo[1,2-c:1',3'-f]pyrazine]-2,5',10'-trione; Spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H), 3'-[3H]indole]-2',5,10(1'H)-trione, 5a,6,7,8-tetrahydro-3-(2-methyl-1-propen-1-yl)-, (2S,3S,5aS)-. CAS No. 182234-26-0. Molecular formula: C21H21N3O3. Mole weight: 363.41. | |
| Tryprostatin A | Tryprostatin A is a natural compound isolated from Aspergillus fumigatus and arrests cell cycle progression at the G2/M phase. Synonyms: (3S,8aS)-3-{[6-methoxy-2-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. Grade: 98%. CAS No. 171864-80-5. Molecular formula: C22H27N3O3. Mole weight: 381.47. | |
| (2,3-Dichlorophenyl)[(6S)-5,6-dihydro-3-(4-methoxy-2-pyridinyl)-6-methyl-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]methanone | (2,3-Dichlorophenyl)[(6S)-5,6-dihydro-3-(4-methoxy-2-pyridinyl)-6-methyl-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]methanone was used in preparation of P2X7 antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 1799971-15-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C19H17Cl2N5O2, Molecular Weight: 418.28. US Biological Life Sciences. | Worldwide |
| 6-Methoxy-3-(methoxymethyl)-5-methylpyrazin-2-amine | 6-Methoxy-3-(methoxymethyl)-5-methylpyrazin-2-amine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pyrazinamine, 6-methoxy-3-(methoxymethyl)-5-methyl- (9CI);6-METHOXY-3-(METHOXYMETHYL)-5-METHYLPYRAZIN-2-AMINE. Product Category: Heterocyclic Organic Compound. CAS No. 91678-86-3. Molecular formula: C8H13N3O2. Mole weight: 183.21. Density: 1.162 g/cm³. Product ID: ACM91678863. Alfa Chemistry ISO 9001:2015 Certified. | |
| Azilsartan mepixetil | Azilsartan mepixetil is an angiotensin II receptor antagonist with renal and cardioprotective effects. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy. Synonyms: 1H-Benzimidazole-7-carboxylic acid, 1-((2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)(1,1'-biphenyl)-4-yl)methyl)-2-ethoxy-, 1-((((3,5,6-trimethyl-2-pyrazinyl)methoxy)carbonyl)oxy)ethyl ester. CAS No. 1596357-16-2. Molecular formula: C36H34N6O8. Mole weight: 678.69. | |
| Bcrp-IN-1 | Bcrp-IN-1 is an inhibitor of breast cancer resistance protein (BCRP) with an IC50 of 0.6 μM against BCRP efflux transporter. Synonyms: (S)-ML753286; (3S,6S,12aS)-6-isobutyl-9-methoxy-3-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione; Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 2,3,6,7,12,12a-hexahydro-9-methoxy-3-methyl-6-(2-methylpropyl)-, (3S,6S,12aS)-. Grade: ≥98%. CAS No. 1699720-85-8. Molecular formula: C20H25N3O3. Mole weight: 355.43. | |
| Fumitremorgin B | Fumitremorgin B is a natural compound isolated from the fermentation broth of Aspergillus fumigatus LN-4. Fumitremorgin B is a tremorgenic mycotoxin that is active against the phytopathogenic fungi. It has antifeedant activity against armyworm (M. separata) larvae when applied to fresh wheat leaves. Synonyms: Lanosulin; 5H,14H-Pyrrolo(1'',2'':4',5')pyrazino(1',2':1,6)pyrido(3,4-b)indole-5,14-dione, 1,2,3,5a,6,11,12,14a-octahydro-5a,6-dihydroxy-9-methoxy-11-(3-methyl-2-butenyl)-12-(2-methyl-1-propenyl)-, (5aR-(5a-alpha,6-alpha,12-beta,14a-alpha))-. Grade: 98.5%. CAS No. 12626-17-4. Molecular formula: C27H33N3O5. Mole weight: 479.57. | |
| FUMITREMORGIN C | Fumitremorgin C, isolated from Aspergillus fumigatus, is a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. Synonyms: tryproquivaline D (2'S-(2'alpha,9'alpha(4R*(S*)),9'abeta))-isomer; tryproquivaline L (9'R-(9'alpha(R*),9'abeta))-isomer; tryproquivaline M (2'S-(2'alpha,9'alpha(4R*(S*)),9'abeta))-isomer; tryproquivaline N (2'S-(2'alpha,9'alpha(R*),9'abeta))-isomer; tryptoquivaline; (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione. Grade: ≥95%. CAS No. 118974-02-0. Molecular formula: C22H25N3O3. Mole weight: 379.45. | |
| GPR40 agonist 1 | GPR40 agonist 1 is a potent full agonist of GPR40 with EC50s of 2 and 17 nM for hGPR40 and rGPR40, respectively. Synonyms: Benzenepropanoic acid, β-cyclopropyl-3-[[5-(5-fluoro-2-methoxy-4-pyridinyl)-6-(2-methylpropyl)-2-pyrazinyl]methoxy]-, (βS)-; (3S)-3-Cyclopropyl-3-(3-((5-(5-fluoro-2-methoxypyridin-4-yl)-6-isobutylpyrazin-2-yl)methoxy)phenyl)propanoic acid. Grade: ≥95%. CAS No. 1853982-41-8. Molecular formula: C27H30FN3O4. Mole weight: 479.54. | |
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