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| Product | Description | |
|---|---|---|
| 2-Amino-3-fluorobenzoyl-5-methylthiophene | 2-Amino-3-fluorobenzoyl-5-methylthiophene. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| 3-Aminomethyl-5-fluorobenzoic Acid Methyl Ester | 3-Aminomethyl-5-fluorobenzoic Acid Methyl Ester is an intermediate used to prepare N-benzyl sulfonamides as 11 β-HSD1 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 886732-31-6. Pack Sizes: 100mg, 1g. Molecular Formula: C9H10FNO2, Molecular Weight: 183.18. US Biological Life Sciences. | Worldwide |
| 5-Amino-2-bromo-4-fluorobenzoic Acid Methyl Ester | 5-Amino-2-bromo-4-fluorobenzoic Acid Methyl Ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 1036389-86-2. Pack Sizes: 250mg. Molecular Formula: C8H7BrFNO2, Molecular Weight: 248.05. US Biological Life Sciences. | Worldwide |
| Exo1 | Exo1 is a cell-permeable and reversible inhibitor of exocytosis (IC50 = 20 μM). Exo1 is a reversible inhibitor of vesicular trafficking between the endoplasmic reticulum and the Golgi apparatus. Exo1 releases ADP-ribosylation factor (ARF)1 from Golgi and disrupts the functions of Golgi. Synonyms: Benzoic acid, 2-[(4-fluorobenzoyl)amino]-, methyl ester; Methyl 2-[(4-fluorobenzoyl)amino]benzoate; 2-(4-Fluoro-benzoylamino)-benzoic acid methyl ester; NSC 214045; Exo1. Grades: 98%. CAS No. 75541-83-2. Molecular formula: C15H12FNO3. Mole weight: 273.26. |  |
| N-((1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide | N-Piperidinyl acetamide derivatives as calcium channel blockers and their use in the treatment of obesity. Group: Biochemicals. Alternative Names: 4-[[ (3-Chloro-5-fluorobenzoyl) amino]methyl]-N- (1, 1-dimethylethyl) -1-piperidineacetamide. Grades: Highly Purified. CAS No. 1199236-64-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-((1-(2-(tert-ButylaMino)-2-oxoethyl)piperidin-4-yl)Methyl)-3-chloro-5-fluorobenzaMide | N-((1-(2-(tert-ButylaMino)-2-oxoethyl)piperidin-4-yl)Methyl)-3-chloro-5-fluorobenzaMide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[[(3-Chloro-5-Fluorobenzoyl)Amino]Methyl]-N-(1,1-Dimethylethyl)-1-Piperidineacetamide. Appearance: White Solid. CAS No. 1199236-64-0. Molecular formula: C19H27ClFN3O2. Mole weight: 384. Purity: 0.98. Product ID: ACM1199236640. Alfa Chemistry ISO 9001:2015 Certified. |  |
| N-((1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide-d9 Hydrochloride Salt | Labeled N-Piperidinyl acetamide derivatives as calcium channel blockers and their use in the treatment of obesity. Group: Biochemicals. Alternative Names: 4-[[ (3-Chloro-5-fluorobenzoyl) amino]methyl]-N- (1, 1-dimethylethyl-d9) -1-piperidineacetamide Hydrochloride Salt. Grades: Highly Purified. CAS No. 1346604-21-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Plevitrexed | Plevitrexed is an orally bioavailable, small molecule, non-polyglutamatable, antifolate quinazoline derivative thymidine synthetase inhibitor with potential antineoplastic activity. Plevitrexed is transported into the cell via the physiological reduced folate carrier (RFC) system. Intracellularly, this agent selectively binds to the folate binding site of thymidylate synthase and inhibits thymidine synthesis, which may result in DNA synthesis inhibition and apoptosis. Uses: Antineoplastic agents. Synonyms: ZD 9331; BGC9331; (αS)-α-[[4-[[(1,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-2-fluorobenzoyl]amino]-1H-tetrazole-5-butanoic Acid; NSC 696259; Vamidex; (2S)-2-((4-(((2,7-Dimethyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl)(prop-2-ynyl)amino)-2-fluorobenzoyl)amino)-4-(1H-tetrazol-5-yl)butanoic acid. Grades: ≥95%. CAS No. 153537-73-6. Molecular formula: C26H25FN8O4. Mole weight: 532.53. | |
| PRX 08066 | PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It can potentially inhibit the pathologic 5-HT-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (PAH). It reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. It shows effects on the vascular muscularization induced by 5-HT in the in vitro studies. It inhibits 5-HT-induced mitogen-activated protein kinase activation and markedly reduces thymidine incorporation in Chinese hamster ovary cells expressing the human 5-HT2BR in vitro. It decrea...ts and mice without affecting the systemic mean arterial pressure in the animals. It is also found to have anti-proliferative and anti-fibrotic effects. It was developed by Allergan company and is in clinical phase 2 with no progression. Uses: Prx 08066 can potentially inhibit the pathologic 5-ht-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (pah). it is also found to have anti-proliferative and anti-fibrotic effects. Synonyms: PRX-08066; PRX 08066; PRX08066. 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]methyl]-2-fluorobenzonitrile. Grades: >98%. CAS No. 866206-54-4. Molecular formula: C19H17ClFN5S. Mole weight: 401.89. | |
| (R)-2-((6-(3-((3-(2-Cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile | An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: 4-Fluorobenzonitrile, (R)-2-((6-(3-((3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-; Trelagliptin Impurity I. Grades: 99%. CAS No. 1917324-13-0. Molecular formula: C31H32F2N8O4. Mole weight: 614.61. | |
| (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzoic acid | An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: Trelagliptin Impurity S. CAS No. 1917324-15-2. Molecular formula: C18H23FN4O4. Mole weight: 378.41. | |
| Trelagliptin Impurity 16 | An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: (R)-2-((6-(3-((3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile. Molecular formula: C31H28F2N8O4. Mole weight: 614.62. | |
| Trelagliptin Impurity 8 | An impurity of Trelagliptin. Trelagliptin is a pharmaceutical drug used for the treatment of type 2 diabetes. Synonyms: (S)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile. Molecular formula: C18H20FN5O2. Mole weight: 357.38. | |
| Trelagliptin succinate | Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Synonyms: (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate; SYR472; SYR472; SYR 472; Trelagliptin, Trelagliptin succinate; brand name: Zafatek. Grades: >98%. CAS No. 1029877-94-8. Molecular formula: C22H26FN5O6. Mole weight: 475.47. | |
| Z 944 | Z 944 is a selective T-type Ca2+ channel blocker with IC50 values are 50 to 160 nM for hCav3.1, hCav3.2 and hCav3.3. Uses: Calcium channel blockers. Synonyms: 4-[[(3-Chloro-5-fluorobenzoyl)amino)methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide; N-((1-(2-(Tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide. Grades: ≥98% by HPLC. CAS No. 1199236-64-0. Molecular formula: C19H27ClFN3O2. Mole weight: 383.89. | |
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