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| Product | Description | |
|---|---|---|
| methylenetetrahydrofolate dehydrogenase (NAD+) | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5,10-methylenetetrahydrofolate:NAD+ oxidoreductase. This enzyme is also called methylenetetrahydrofolate dehydrogenase (NAD+). This enzyme participates in one carbon pool by folate. Group: Enzymes. Synonyms: methylenetetrahydrofolate dehydrogenase (NAD+). Enzyme Commission Number: EC 1.5.1.15. CAS No. 82062-90-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1496; methylenetetrahydrofolate dehydrogenase (NAD+); EC 1.5.1.15; 82062-90-6; methylenetetrahydrofolate dehydrogenase (NAD+). Cat No: EXWM-1496. |  |
| methylenetetrahydrofolate dehydrogenase (NADP+) | In eukaryotes, occurs as a trifunctional enzyme also having methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) and formate-tetrahydrofolate ligase(EC 6.3.4.3) activity. In some prokaryotes occurs as a bifunctional enzyme also having methenyltetrahydrofolate cyclohydrolase activity (EC 3.5.4.9). Group: Enzymes. Synonyms: N5,N10-methylenetetrahydrofolate dehydrogenase; 5,10-methylenetetrahydrofolate:NADP oxidoreductase; 5,10-methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase (NADP). Enzyme Commission Number: EC 1.5.1.5. CAS No. 9029-14-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1531; methylenetetrahydrofolate dehydrogenase (NADP+); EC 1.5.1.5; 9029-14-5; N5,N10-methylenetetrahydrofolate dehydrogenase; 5,10-methylenetetrahydrofolate:NADP oxidoreductase; 5,10-methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase (NADP). Cat No: EXWM-1531. | |
| methylenetetrahydrofolate reductase (ferredoxin) | An iron-sulfur flavoprotein that also contains zinc. The enzyme from Clostridium formicoaceticum catalyses the reduction of methylene blue, menadione, benzyl viologen, rubredoxin or FAD with 5-methyltetrahydrofolate and the oxidation of reduced ferredoxin or FADH2 with 5,10-methylenetetrahydrofolate. However, unlike EC 1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H], there is no activity with NAD(P)H. Group: Enzymes. Synonyms: 5,10-methylenetetrahydrofolate reductase. Enzyme Commission Number: EC 1.5.7.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1558; methylenetetrahydrofolate reductase (ferredoxin); EC 1.5.7.1; 5,10-methylenetetrahydrofolate reductase. Cat No: EXWM-1558. | |
| methylenetetrahydrofolate reductase [NAD(P)H] | A flavoprotein (FAD). Menadione can also serve as an electron acceptor. Group: Enzymes. Synonyms: methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase; 5,10-methylenetetrahydrofolate reductase (NADPH); 5,10-methylenetetrahydrofolic acid reductase; 5,10-CH2-H4folate reductase; methylenetetrahydrofolate reductase (NADP. Enzyme Commission Number: EC 1.5.1.20. CAS No. 71822-25-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1502; methylenetetrahydrofolate reductase [NAD(P)H]; EC 1.5.1.20; 71822-25-8; methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase; 5,10-methylenetetrahydrofolate reductase (NADPH); 5,10-methylenetetrahydrofolic acid reductase; 5,10-CH2-H4folate reductase; methylenetetrahydrofolate reductase (NADPH2); 5-methyltetrahydrofolate:NAD+ oxidoreductase; 5-methyltetrahydrofolate:NAD+ oxidoreductase; methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase; 5,10-methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase; N5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydropteroylglutamate reductase; N5,N10-methylenetetrahydrofolate reductase; methylenetetrahydrofolic acid reductase; 5-methyltetrahydrofolate:(acceptor) | |
| methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase (FADH2-oxidizing) | Up to 25% of the bases in mature tRNA are post-translationally modified or hypermodified. One almost universal post-translational modification is the conversion of U54 into ribothymidine in the TψC loop, and this modification is found in most species studied to date. Unlike this enzyme, which uses 5,10-methylenetetrahydrofolate and FADH2 to supply the atoms for methylation of U54, EC 2.1.1.35, tRNA (uracil54-C5)-methyltransferase, uses S-adenosyl-L-methionine. Group: Enzymes. Synonyms: folate-dependent ribothymidyl synthase; methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase; 5,10-methylenetetrahydrofolate:tRNA-UψC (uracil-5-)-methyl-tran. Enzyme Commission Number: EC 2.1.1.74. CAS No. 56831-74-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1975; methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase (FADH2-oxidizing); EC 2.1.1.74; 56831-74-4; folate-dependent ribothymidyl synthase; methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase; 5,10-methylenetetrahydrofolate:tRNA-UψC (uracil-5-)-methyl-transferase; 5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyl-transferase; TrmFO; folate/FAD-dependent tRNA T54 methyltransferase. Cat No: EXWM-1975. | |
| methylenetetrahydromethanopterin dehydrogenase | Coenzyme F420 is a 7,8-didemethyl-8-hydroxy-5-deazariboflavin derivative; methanopterin is a pterin analogue. The enzyme is involved in the formation of methane from CO2 in the methanogen Methanothermobacter thermautotrophicus. Group: Enzymes. Synonyms: N5,N10-methylenetetrahydromethanopterin dehydrogenase; 5,10-methylenetetrahydromethanopterin dehydrogenase. Enzyme Commission Number: EC 1.5.98.1. CAS No. 100357-01-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1564; methylenetetrahydromethanopterin dehydrogenase; EC 1.5.98.1; 100357-01-5; N5,N10-methylenetetrahydromethanopterin dehydrogenase; 5,10-methylenetetrahydromethanopterin dehydrogenase. Cat No: EXWM-1564. | |
| 5,10-methylenetetrahydromethanopterin reductase | Catalyses an intermediate step in methanogenesis from CO2 and H2 in methanogenic archaea. Group: Enzymes. Synonyms: 5,10-methylenetetrahydromethanopterin cyclohydrolase; N5,N10-methylenetetrahydromethanopterin reductase; methylene-H4MPT reductase; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase; N5, N10-methylenetetrahydromethanopterin: coenzyme-F420 oxidoreductase. Enzyme Commission Number: EC 1.5.98.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1565; 5,10-methylenetetrahydromethanopterin reductase; EC 1.5.98.2; 5,10-methylenetetrahydromethanopterin cyclohydrolase; N5,N10-methylenetetrahydromethanopterin reductase; methylene-H4MPT reductase; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase; N5, N10-methylenetetrahydromethanopterin: coenzyme-F420 oxidoreductase. Cat No: EXWM-1565. | |
| (R)-1-((2-(2,4-difluorophenyl)-4-methylenetetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole | (R)-1-((2-(2,4-difluorophenyl)-4-methylenetetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 1370190-85-4. Molecular formula: C14H13F2N3O. Mole weight: 277.27. |  |
| 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine | 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine, an influential antiviral agent, exhibits exceptional efficacy against a spectrum of viral ailments encompassing hepatitis C and HIV. It exerts its prohibition on viral RNA production and duplication, thereby effectively hindering the advancement of these afflictions. Synonyms: 1-((2R,3R,4R)-3-Fluoro-4-hydroxy-5-methylenetetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2,5-Dideoxy-2-fluoro-β-D-erythro-pent-4-enofuranosyl)-2,4(1H,3H)-pyrimidinedione; Uridine, 4',5'-didehydro-2',5'-dideoxy-2'-fluoro-. Grades: ≥95%. CAS No. 1365255-75-9. Molecular formula: C9H9FN2O4. Mole weight: 228.18. | |
| 4',5'-Didehydro-2',5'-dideoxyuridine | 4',5'-Didehydro-2',5'-dideoxyuridine is an esteemed antiviral agent, boasting remarkable efficacy in studying viral infections primarily instigated by the notorious herpes viruses. Its mode of action involves impeding the replication of viral DNA, thereby showcasing its proficiency in research of afflictions such as herpes simplex virus (HSV), varicella-zoster virus (VZV) is and cytomegalovirus (CMV). Synonyms: Uridine, 4',5'-didehydro-2',5'-dideoxy-; 1-((2R,4S)-4-hydroxy-5-methylenetetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 58096-66-5. Molecular formula: C9H10N2O4. Mole weight: 210.19. | |
| 4',5'-Didehydro-5'-deoxyadenosine | 4',5'-Didehydro-5'-deoxyadenosine is a crucial biomolecular entity showcasing applications in research of multifarious afflictions, encompassing the pernicious cancer, treacherous viral invasions is and vexing autoimmune disorders. Synonyms: 1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)adenine; (2R,3R,4S)-2-(6-amino-9H-purin-9-yl)-5-methylenetetrahydrofuran-3,4-diol; 9-(5-deoxy-β-erythro-pent-4-enofuranosyl)adenine. Grades: ≥95%. CAS No. 20535-04-0. Molecular formula: C10H11N5O3. Mole weight: 249.23. | |
| 4',5'-Didehydro-5'-deoxythymidine | 4',5'-Didehydro-5'-deoxythymidine, a potent antiviral agent, exhibits remarkable efficacy in combatting a multitude of viral afflictions encompassing human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV). By imposing a formidable inhibition upon reverse transcriptase, an indispensable viral replication enzyme, its therapeutic prowess manifests. Synonyms: 1-(2,5-dideoxy-β-D-glycero-pent-4-enofuranosyl)thymine; 4',5'-didehydro-5'-deoxy-thymidine; 5'-Deoxy-4',5'-didehydrothymidine; 1-((2R,4S)-4-hydroxy-5-methylenetetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,4S)-4-Hydroxy-5-methylenetetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 28034-72-2. Molecular formula: C10H12N2O4. Mole weight: 224.22. | |
| 4',5'-Didehydro-5'-deoxyuridine | 4',5'-Didehydro-5'-deoxyuridine, a remarkable antiviral agent employed extensively in biomedical research, exhibits remarkable prowess in quelling the replication of specific viral DNA and RNA. Synonyms: 1-(5-Deoxy-b-D-erythro-pent-4-enofuranosyl)uracil; 1-((2R,3R,4S)-3,4-dihydroxy-5-methylenetetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 4,5-Didehydro-5-deoxyuridine; Uridine, 4',5'-didehydro-5'-deoxy-; 1-(5-Deoxy-β-D-erythro-pent-4-enofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 14365-63-0. Molecular formula: C9H10N2O5. Mole weight: 226.19. | |
| 5,10-methenyltetrahydromethanopterin hydrogenase | Does not catalyse the reduction of artificial dyes. Does not by itself catalyse a H2/H+ exchange reaction. Does not contain nickel or iron-sulfur clusters. Group: Enzymes. Synonyms: H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase; nonmetal hydrogenase; N5,N10-methenyltetrahydromethanopterin hydrogenase; hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase. Enzyme Commission Number: EC 1.12.98.2. CAS No. 100357-01-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0525; 5,10-methenyltetrahydromethanopterin hydrogenase; EC 1.12.98.2; 100357-01-5; H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase; nonmetal hydrogenase; N5,N10-methenyltetrahydromethanopterin hydrogenase; hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase. Cat No: EXWM-0525. | |
| ANX-510 | ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44. | |
| Canadensolide | Canadensolide is a bislactone antibiotic isolated from Penicillium canadense, Aspergillus flavus and A. tamarii. It shows antifungal activity. Synonyms: (-)-Canadensolide; Furo(3,4-b)furan-2,4-dione, 6-butyltetrahydro-3-methylene-, (3aS,6R,6aR)-; (3aS,6R,6aR)-6-Butyl-3-methylenetetrahydrofuro[3,4-b]furan-2,4-dione. CAS No. 20421-31-2. Molecular formula: C11H14O4. Mole weight: 210.23. | |
| Chlorendic Acid | Chlorendic acid appears as fine white free-flowing crystals or white powder. Odorless. (NTP, 1992). Uses: Chlorendic acid is used as a flame retardant in polyurethane foams, resins, plasticizers, coatings, epoxy resins, and wool fabrics; in the manufacture of alkyl resins for special paints and inks; in the manufacture of polyester resins with special applications in electrical systems,paneling, engineering plastics, and paint; and in the manufacture of corrosion-resistant tanks, piping, and scrubbers. Group: Micro/nanoelectronicsdicarboxylic acid monomers. Alternative Names: Het Acid; 1,4,5,6,7,7-Hexachlorobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic Acid; Hexachloro-endo-methylenetetrahydrophthalic Acid. CAS No. 115-28-6. Molecular formula: C9H4Cl6O4. Mole weight: 388.83 g/mol. Appearance: White to Almost White Powder to Crystal. Purity: 98.0%(T). IUPACName: 1,4,5,6,7,7-hexachlorobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid. Canonical SMILES: OC (=O)C1C (C (O)=O)[C@]2 (Cl)C (Cl)=C (Cl)[C@@]1 (Cl)C2 (Cl)Cl. Density: 1.7157 g/cm³. ECNumber: 204-078-9. Catalog: ACM-MO-115286. |  |
| Doxycycline EP Impurity B | Meclocycline is a semi-synthetic tetracycline prepared by dehydrating the 6-hydroxyl group of oxytetracycline. It has a wide range of antibacterial and antiprotozoal activities. Meclocycline is an impurity of Doxycycline, which is a semisynthetic, broad-spectrum tetracycline antibiotic used in the treatment of infections caused by bacteria and certain parasites. Uses: Antibiotics, tetracycline. Synonyms: Doxycycline hyclate EP impurity B; Doxycycline monohydrate EP impurity B; 6-Methyleneoxytetracycline; Metacycline; Rondomycin; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4S,4aR,5S,5aR,12aS)-; (4S,4aR,5S,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, [4S-(4α, 4aα, 5α, 5aα, 12aα)]-; 6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline; 6-Deoxy-6-methylene-6-demethyl-5-hydroxytetracycline; 6-Methylene-5-hydroxytetracycline; 6-Methyleneoxytetracycline; Bialatan; GS 2876; Oxytetracycline, 6-methylene-; Rondomycin; Tri-methacycline. Grades: >98% by HPLC. CAS No. 914-00-1. Molecular formula: C22H22N2O8. Mole weight: 442.42. | |
| Eribulin Impurity 26 | Eribulin Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-((2S,5S)-5-(2-((2S,4R,6R)-6-(((2S,3S,4S,5R)-5-((S)-2,3-bis((tert-butyldimethylsilyl)oxy)propyl)-4-methoxy-3-(tosylmethyl)tetrahydrofuran-2-yl)methyl)-4-methyl-5-methylenetetrahydro-2H-pyran-2-yl)ethyl)-4-methylenetetrahydrofuran-2-yl)propan-1-ol. Molecular Formula: C46H80O9SSi2. Mole Weight: 865.36. Catalog: APB05769. |  |
| Eribulin Impurity 29 | Eribulin Impurity 29. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-((2S,5S)-5-(2-((2S,4R,6R)-6-(((2S,3S,4R,5S)-5-((S)-2,3-bis((tert-butyldimethylsilyl)oxy)propyl)-4-methoxy-3-(tosylmethyl)tetrahydrofuran-2-yl)methyl)-4-methyl-5-methylenetetrahydro-2H-pyran-2-yl)ethyl)-4-methylenetetrahydrofuran-2-yl)propan-1-ol. Molecular Formula: C46H80O9SSi2. Mole Weight: 865.36. Catalog: APB05767. | |
| Eribulin Impurity 8 | Eribulin Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3- ( (2S, 5S) -5- (2- ( (2S, 4R, 6R) -6- ( ( (2S, 3S, 4R, 5R) -5- ( (S) -2, 3-bis ( (tert-butyldimethylsilyl) oxy) propyl) -4-methoxy-3- ( (phenylsulfonyl) methyl) tetrahydrofuran-2-yl) methyl) -4-methyl-5-methylenetetrahydro-2H-pyran-2-yl) ethyl) -4-methylenetetrahydrofuran-2-yl) propan-1-ol. CAS No. 253128-10-8. Molecular Formula: C45H78O9SSi2. Mole Weight: 851.33. Catalog: APB253128108. | |
| Folitixorin | Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5,10-Methylenetetrafolate; ANX-510 free acid. CAS No. 3432-99-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-14769. |  |
| formate-tetrahydrofolate ligase | In eukaryotes occurs as a trifunctional enzyme also having methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) and methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) activity. Group: Enzymes. Synonyms: formyltetrahydrofolate synthetase; 10-formyltetrahydrofolate synthetase; tetrahydrofolic formylase; tetrahydrofolate formylase. Enzyme Commission Number: EC 6.3.4.3. CAS No. 9023-66-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5795; formate-tetrahydrofolate ligase; EC 6.3.4.3; 9023-66-9; formyltetrahydrofolate synthetase; 10-formyltetrahydrofolate synthetase; tetrahydrofolic formylase; tetrahydrofolate formylase. Cat No: EXWM-5795. | |
| L-Serine Hydroxymethyltransferase (Crude Enzyme) | Serine hydroxymethyltransferase (SHMT) is a PLP dependent enzyme (EC 2. 1. 2. 1) which plays an important role in cellular one-carbon pathways by catalyzing the reversible, simultaneous conversions of L-serine to glycine and tetrahydrofolate (THF) to 5,10-methylenetetrahydrofolate. This reaction provides the largest part of the one-carbon units available to the cell. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Pharmacology; medicine; synthesis; analysis. Group: Enzymes. Synonyms: serine aldolase; threonine aldolase; serine hydroxymethylase; serine hydroxymethyltransferase; allothreonine aldolase; L-serine hydroxymethyltransferase; L-threonine aldolase; serine hydroxymethyltransferase; serine transhydroxymethylase. Enzyme Commission Number: EC 2.1.2.1. CAS No. 9029-83-8. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. serine aldolase; threonine aldolase; serine hydroxymethylase; serine hydroxymethyltransferase; allothreonine aldolase; L-serine hydroxymethyltransferase; L-threonine aldolase; serine hydroxymethyltransferase; serine transhydroxymethylase. Pack: 100ml. Cat No: NATE-1809. | |
| methenyltetrahydrofolate cyclohydrolase | In eukaryotes, the enzyme occurs as a trifunctional enzyme that also has methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) and formate-tetrahydrofolate ligase (EC 6.3.4.3) activity. In some prokaryotes, it occurs as a bifunctional enzyme that also has dehydrogenase (EC 1.5.1.5) activity or formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) activity. Group: Enzymes. Synonyms: Citrovorum factor cyclodehydrase; cyclohydrolase; formyl-methenyl-methylenetetrahydrofolate synthetase (combined); 5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing). Enzyme Commission Number: EC 3.5.4.9. CAS No. 9027-97-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4577; methenyltetrahydrofolate cyclohydrolase; EC 3.5.4.9; 9027-97-8; Citrovorum factor cyclodehydrase; cyclohydrolase; formyl-methenyl-methylenetetrahydrofolate synthetase (combined); 5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing). Cat No: EXWM-4577. | |
| sarcosine dehydrogenase | A flavoprotein (FMN). Tetrahydrofolate is also a substrate, being converted to N5,N10-methylenetetrahydrofolate. Group: Enzymes. Synonyms: sarcosine N-demethylase; monomethylglycine dehydrogenase; sarcosine:(acceptor) oxidoreductase (demethylating). Enzyme Commission Number: EC 1.5.8.3. CAS No. 37228-65-2, 93389-49-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1562; sarcosine dehydrogenase; EC 1.5.8.3; 37228-65-2, 93389-49-2; sarcosine N-demethylase; monomethylglycine dehydrogenase; sarcosine:(acceptor) oxidoreductase (demethylating). Cat No: EXWM-1562. | |
| Stevioside | Stevioside is a glycoside from the stevia plant. Stevioside is a natural sweetening agent with sweetness about 250 times that of sugar with negligible effect on blood glucose. Stevioside, much like other steviol glycoside is known for its application in treatment of many diseases like diabetes and high blood pressure. It is also used as a food additive and in dietary supplements. Synonyms: Kaur-16-en-18-oic acid, 13-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-, β-D-glucopyranosyl ester, (4α)-; 1,2-Stevioside; E 960; Stevian 50; Steviosin; α-G-Sweet; (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (4R,4aS,6aR,9S,11aR,11bS)-9-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylate. Grades: >98%. CAS No. 57817-89-7. Molecular formula: C38H60O18. Mole weight: 804.87. | |
| Tetrahydrofolic acid | Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid [1]. Uses: Scientific research. Group: Natural products. Alternative Names: L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid. CAS No. 135-16-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14520. | |
| thymidylate synthase | Thymidylate synthetase (EC 2.1.1.45) is an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP). Thymidine is one of the nucleotides in DNA. With inhibition of TS, an imbalance of deoxynucleotides and increased levels of dUMP arise. Both cause DNA damage. Group: Enzymes. Synonyms: dTMP synthase; thymidylate synthetase; methylenetetrahydrofolate:dUMP C-methyltransferase; TMP synthetase. Enzyme Commission Number: EC 2.1.1.45. CAS No. 9031-61-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1949; thymidylate synthase; EC 2.1.1.45; 9031-61-2; dTMP synthase; thymidylate synthetase; methylenetetrahydrofolate:dUMP C-methyltransferase; TMP synthetase. Cat No: EXWM-1949. | |
| thymidylate synthase (FAD) | Contains FAD. All thymidylate synthases catalyse a reductive methylation involving the transfer of the methylene group of 5,10-methylenetetrahydrofolate to the C5 position of dUMP and a two electron reduction of the methylene group to a methyl group. Unlike the classical thymidylate synthase, ThyA (EC 2.1.1.45), which uses folate as both a 1-carbon donor and a source of reducing equivalents, this enzyme uses a flavin coenzyme as a source of reducing equivalents, which are derived from NADPH. Group: Enzymes. Synonyms: Thy1; ThyX. Enzyme Commission Number: EC 2.1.1.148. CAS No. 850167-13-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1744; thymidylate synthase (FAD); EC 2.1.1.148; 850167-13-4; Thy1; ThyX. Cat No: EXWM-1744. | |
| tRNA (uracil54-C5)-methyltransferase | Unlike this enzyme, EC 2.1.1.74 (methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase (FADH2-oxidizing)), uses 5,10-methylenetetrahydrofolate and FADH2 to supply the atoms for methylation of U54. Group: Enzymes. Synonyms: transfer RNA uracil54 5-methyltransferase; transfer RNA uracil54 methylase; tRNA uracil54 5-methyltransferase; m5U54-methyltransferase; tRNA:m5U54-methyltransferase; RUMT; TrmA; 5-methyluridine54 tRNA methyltransferase; tRNA(uracil-54,C5)-methyltransferase; Trm2; tRNA(m5U54)methyltransferase. Enzyme Commission Number: EC 2.1.1.35. CAS No. 37257-02-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1939; tRNA (uracil54-C5)-methyltransferase; EC 2.1.1.35; 37257-02-6; transfer RNA uracil54 5-methyltransferase; transfer RNA uracil54 methylase; tRNA uracil54 5-methyltransferase; m5U54-methyltransferase; tRNA:m5U54-methyltransferase; RUMT; TrmA; 5-methyluridine54 tRNA methyltransferase; tRNA(uracil-54,C5)-methyltransferase; Trm2; tRNA(m5U54)methyltransferase. Cat No: EXWM-1939. | |
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