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Also converts 3-oxopropanoate into acetyl-CoA. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product. Group: Enzymes. Synonyms: MSDH; MMSA dehydrogenase; iolA (gene name); methylmalonate-semialdehyde dehydrogenase (acylating). Enzyme Commission Number: EC 1.2.1.27. CAS No. 37205-49-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1133; methylmalonate-semialdehyde dehydrogenase (CoA-acylating); EC 1.2.1.27; 37205-49-5; MSDH; MMSA dehydrogenase; iolA (gene name); methylmalonate-semialdehyde dehydrogenase (acylating). Cat No: EXWM-1133.
Diethyl (chlorocarbonyloxy)methylmalonate
Diethyl (chlorocarbonyloxy)methylmalonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 282-441-0, Diethyl (chlorocarbonyloxy)methylmalonate, 84209-30-3. Product Category: Heterocyclic Organic Compound. CAS No. 84209-30-3. Molecular formula: C9H13ClO6. Mole weight: 252.648920 [g/mol]. Purity: 0.96. IUPACName: diethyl 2-carbonochloridoyloxy-2-methylpropanedioate. Canonical SMILES: CCOC(=O)C(COC(=O)Cl)C(=O)OCC. Density: 1.267g/cm³. ECNumber: 282-441-0. Product ID: ACM84209303. Alfa Chemistry ISO 9001:2015 Certified.
Diethylmethylmalonate
Diethylmethylmalonate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1H-indol-3-yl acetate. Product Category: Heterocyclic Organic Compound. Appearance: white to off-white crystalline powder. CAS No. 608-08-5. Molecular formula: C10H9NO2. Mole weight: 175.184. Purity: 0.96. IUPACName: INDOXYL ACETATE. Density: 1.255 g/cm³. Product ID: ACM608085. Alfa Chemistry ISO 9001:2015 Certified. Categories: DIETHYL METHYLMALONATE.
2-Allyl-2-methylmalonic Acid Eiethyl Ester
Can be used in the preparation of Meprobamate and its metabolites. Group: Biochemicals. Alternative Names: Diethyl Allylmethylmalonate; 2-Methyl-2-(2-propen-1-yl)-propanedioic Acid 1,3-Diethyl Ester. Grades: Highly Purified. CAS No. 53651-72-2. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
3-hydroxyisobutyrate dehydrogenase
3-hydroxyisobutyrate dehydrogenase is a tetrameric mitochondrial enzyme that catalyzes the NAD+-dependent, reversible oxidation of 3-hydroxyisobutyrate, an intermediate of valine catabolism, to methylmalonate semialdehyde. Group: Enzymes. Synonyms: β-hydroxyisobutyrate dehydrogenase. Enzyme Commission Number: EC 1.1.1.31. CAS No. 9028-39-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0221; 3-hydroxyisobutyrate dehydrogenase; EC 1.1.1.31; 9028-39-1; β-hydroxyisobutyrate dehydrogenase. Cat No: EXWM-0221.
arylmalonate decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. Group: Enzymes. Synonyms: AMDASE; 2-aryl-2-methylmalonate carboxy-lyase; 2-aryl-2-methylmalonate carboxy-lyase (2-arylpropionate-forming). Enzyme Commission Number: EC 4.1.1.76. CAS No. 144713-36-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4824; arylmalonate decarboxylase; EC 4.1.1.76; 144713-36-0; AMDASE; 2-aryl-2-methylmalonate carboxy-lyase; 2-aryl-2-methylmalonate carboxy-lyase (2-arylpropionate-forming). Cat No: EXWM-4824.
Carprofen EP Impurity F
Carprofen EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: diethyl 2-(6-chloro-9H-carbazol-2-yl)-2-methylmalonate. CAS No. 71208-55-4. Molecular Formula: C20H20ClNO4. Mole Weight: 373.83. Catalog: APB71208554.
Cinnamyl acetate
Cinnamyl acetate. CAS No. 103-54-8. Pack Sizes: 250 mL in glass bottle. Product ID: CDC10-0194. Molecular formula: C11H12O2. Category: Flavoring Chemical Agents. Product Keywords: Cosmetic Ingredients; Flavoring Chemical Agents; Cinnamyl acetate; CDC10-0194; 103-54-8; C11H12O2; 203-121-9; MFCD00008722; 103-54-8. Purity: 0.99. EC Number: 203-121-9. Physical State: Powder. Solubility: alcohol: soluble(lit.). Quality Level: 100. Boiling Point: 265 °C (lit.). Melting Point: 30 °C. Density: 1.057 g/mL at 25 °C. Product Description: Cinnamyl acetate is a fragrance ingredient. Palladium catalyzed allylic alkylation of cinnamyl acetate using sodium diethyl 2-methylmalonate and novel ferrocenyl Schiff base has been investigated.
Flurbiprofen Impurity 33
Flurbiprofen Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: diethyl 2-(3-fluoro-4-nitrophenyl)-2-methylmalonate. CAS No. 78543-06-3. Molecular Formula: C14H16FNO6. Mole Weight: 313.28. Catalog: APB78543063.
Flurbiprofen Impurity 34
Flurbiprofen Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: diethyl 2-(4-amino-3-fluorophenyl)-2-methylmalonate. CAS No. 78543-08-5. Molecular Formula: C14H18FNO4. Mole Weight: 283.30. Catalog: APB78543085.
Methylmalonic acid
Methylmalonate, a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A (methylmalonyl-CoA), binds with coenzyme A to form methylmalonyl-CoA. It is a reversible succinate dehydrogenase inhibitor used to generate Huntington's disease models and induces apoptotic cell death in striatal neurons. Synonyms: 2-methylpropanedioic acid. Grades: > 98 %. CAS No. 516-05-2. Molecular formula: C4H6O4. Mole weight: 118.09.
Methylmalonic acid
Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer. Uses: Scientific research. Group: Natural products. Alternative Names: Methylpropanedioic acid; Methylmalonate. CAS No. 516-05-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-103395.
Methylmalonic acid-d3
Methylmalonic acid-d 3 is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Methylpropanedioic acid-d3; Methylmalonate-d3. CAS No. 42522-59-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-103395S.
2-((2S,3S)-1-(tert-Butyldimethylsilyl)-3-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-4-oxoazetidin-2-yl)-2-methylmalonic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 156630-85-2, 2-((2S,3S)-1-(tert-butyldimethylsilyl)-3-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-4-oxoazetidin-2-yl)-2-methylmalonic acid. Product Category: Heterocyclic Organic Compound. CAS No. 156630-85-2. Molecular formula: C21H41NO6Si2. Mole weight: 459.724340 [g/mol]. Purity: 0.96. IUPACName: 2-[(2S,3S)-1-[tert-butyl(dimethyl)silyl]-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]-2-methylpropanedioic acid. Canonical SMILES: CC(C1C(N(C1=O)[Si](C)(C)C(C)(C)C)C(C)(C(=O)O)C(=O)O)O[Si](C)(C)C(C)(C)C. Product ID: ACM156630852. Alfa Chemistry ISO 9001:2015 Certified.
2-[4-(1,1-Dicarboethoxy)benzyl]-2-methyl Malonic Acid-d3. Group: Biochemicals. Alternative Names: 2-[4-(2,2-Dicarboxy-propyl)-phenyl]-2-methylmalonic Acid-d3; [[4- (1, 1-Dicarboxyethyl) phenyl]methyl]methyl-propanedioic Acid-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
2-(5-fluoropentyl)-2-methylmalonic acid
This molecular is a [18F] PET (positron emission tomography) radiotracer. It can accumulate in cells presenting apoptosis-specific membrane alterations. ML-10 allows for the detection of apoptotic cells located in atherosclerotic plaques. In Jun 2015, GlaxoSmithKline terminated a phase II trial in Solid tumours (Diagnosis) in United Kingdom. In Mar 2016, Phase-II for solid tumours, lung cancer and head Brain metastases and neck cancer (Diagnosis) in USA was suspended. Uses: Used as an cancer diagnostic reagents. Synonyms: ML 10;[18F]-ML-10; ApoSense-PET; F-18-ML-10. Grades: 98%. CAS No. 1216897-16-3. Molecular formula: C9H15FO4. Mole weight: 206.21.
2-Methylcitric acid
2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Methylcitric acid. CAS No. 6061-96-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-113371.
2-Methylcitric Acid
2-Methylcitric Acid is a metabolite of Citric Acid. It is formed from the condensation of propionoyl-CoA and oxaloacetic acid catalyzed by a citrate synthase enzyme. 2-Methylcitric acid is an endogenous tricarboxylic acid formed by the condensation of propionyl-CoA with oxaloacetic acid by citrate synthase under conditions of propionyl-CoA accumulation. Accumulation of 2-methylcitric acid is associated with cobalamin deficiencies, propionic acidemia, and methylmalonic acidurias. Group: Biochemicals. Alternative Names: 2-Hydroxy-1,2,3-butanetricarboxylic Acid. Grades: Highly Purified. CAS No. 6061-96-7. Pack Sizes: 50mg, 250mg. Molecular Formula: C?H??O?, Molecular Weight: 206.15. US Biological Life Sciences.
Worldwide
2-methylfumaryl-CoA hydratase
The enzyme from the bacterium Chloroflexus aurantiacus is part of the 3-hydroxypropanoate cycle for carbon assimilation. Group: Enzymes. Synonyms: Mcd; erythro-β-methylmalonyl-CoA hydrolyase; mesaconyl-coenzyme A hydratase (ambiguous); mesaconyl-C1-CoA hydratase. Enzyme Commission Number: EC 4.2.1.148. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4989; 2-methylfumaryl-CoA hydratase; EC 4.2.1.148; Mcd; erythro-β-methylmalonyl-CoA hydrolyase; mesaconyl-coenzyme A hydratase (ambiguous); mesaconyl-C1-CoA hydratase. Cat No: EXWM-4989.
2-Methylmalonodiamide
White crystalline, 98%. Synonyms: 2-Methylpropanediamide. CAS No. 1113-63-9. Pack Sizes: 5g, 25g. Product ID: FR-0212. M.P. 208-210. Mole weight: 116.12.
Frinton Laboratories
Adenosylcobalamin
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B 12 which is a cofactor for methylmalonyl CoA mutase [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Coenzyme B12; Cobamamide; AdoCbl. CAS No. 13870-90-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-112790.
This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. This enzyme participates in biotin metabolism. Group: Enzymes. Synonyms: biotin-[methylmalonyl-CoA-carboxyltransferase] synthetase; biotin-methylmalonyl coenzyme A carboxyltransferase synthetase; biotin-transcarboxylase synthetase; methylmalonyl coenzyme A holotranscarboxylase synthetase; biotin-[methylmalonyl-CoA-carboxyltransferase] ligase; biotin:apo[methylmalonyl-CoA:pyruvate carboxyltransferase] ligase (AMP-forming). Enzyme Commission Number: EC 6.3.4.9. CAS No. 37318-66-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5801; biotin-[methylmalonyl-CoA-carboxytransferase] ligase; EC 6.3.4.9; 37318-66-4; biotin-[methylmalonyl-CoA-carboxyltransferase] synthetase; biotin-methylmalonyl coenzyme A carboxyltransferase synthetase; biotin-transcarboxylase synthetase; methylmalonyl coenzyme A holotranscarboxylase synthetase; biotin-[methylmalonyl-CoA-carboxyltransferase] ligase; biotin:apo[methylmalonyl-CoA:pyruvate carboxyltransferase] ligase (AMP-forming). Cat No: EXWM-5801.
carboxybiotin decarboxylase
The integral membrane protein MadBfrom the anaerobic bacterium Malonomonas rubra is a component of the multienzyme complex EC 4.1.1.89, biotin-dependent malonate decarboxylase. The free energy of the decarboxylation reaction is used to pump Na+ out of the cell. The enzyme is a member of the Na+-translocating decarboxylase family, other members of which include EC 4.1.1.3 (oxaloacetate decarboxylase) and EC 4.1.1.41 (methylmalonyl-CoA decarboxylase). Group: Enzymes. Synonyms: MadB; carboxybiotin protein decarboxylase. Enzyme Commission Number: EC 7.2.4.1 (Formerly EC 4.3.99.2). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5309; carboxybiotin decarboxylase; EC 4.3.99.2; MadB; carboxybiotin protein decarboxylase. Cat No: EXWM-5309.
ethylmalonyl-CoA decarboxylase
The enzyme, which exists in all vertebrates, decarboxylates ethylmalonyl-CoA, a potentially toxic compound that is formed in low amounts by the activity of EC 6.4.1.2 (acetyl-CoA carboxylase) and EC 6.4.1.3 (propanoyl-CoA carboxylase). It prefers the S isomer, and can decarboxylate (R)-methylmalonyl-CoA with lower efficiency. cf. EC 4.1.1.41 (methylmalonyl-CoA decarboxylase). Group: Enzymes. Enzyme Commission Number: EC 4.1.1.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4844; ethylmalonyl-CoA decarboxylase; EC 4.1.1.94. Cat No: EXWM-4844.
Methylmalonic Acid
Binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status. Group: Biochemicals. Alternative Names: 2-Methylpropanedioic Acid; Methylpropanedioic Acid; 1,1-Ethanedicarboxylic Acid; Isosuccinic Acid; NSC 25201. Grades: Highly Purified. CAS No. 516-05-2. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Methylmalonic Acid-d3
An isotope labeled derivative of Methylmalonic Acid , binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status. Group: Biochemicals. Alternative Names: Methyl-d3-propanedioic Acid; 2-Methyl-d3-propanedioic Acid; 1,1-Ethanedicarboxylic Acid-d3; Isosuccinic Acid-d3; NSC 2520-d3. Grades: Highly Purified. CAS No. 42522-59-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
methylmalonyl-CoA carboxytransferase
A biotinyl-protein, containing cobalt and zinc. Group: Enzymes. Synonyms: transcarboxylase; methylmalonyl coenzyme A carboxyltransferase; methylmalonyl-CoA transcarboxylase; oxalacetic transcarboxylase; methylmalonyl-CoA carboxyltransferase; methylmalonyl-CoA carboxyltransferase; (S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase; (S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxytransferase carboxytransferase [incorrect]. Enzyme Commission Number: EC 2.1.3.1. CAS No. 9029-86-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2011; methylmalonyl-CoA carboxytransferase; EC 2.1.3.1; 9029-86-1; transcarboxylase; methylmalonyl coenzyme A carboxyltransferase; methylmalonyl-CoA transcarboxylase; oxalacetic transcarboxylase; methylmalonyl-CoA carboxyltransferase; methylmalonyl-CoA carboxyltransferase; (S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase; (S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxytransferase carboxytransferase [incorrect]. Cat No: EXWM-2011.
methylmalonyl-CoA epimerase
It is an enzyme involved in fatty acid catabolism that is encoded in human by the "MCEE" gene located on chromosome 2. Group: Enzymes. Synonyms: methylmalonyl-CoA racemase; methylmalonyl coenzyme A racemase; DL-methylmalonyl-CoA racemase; 2-methyl-3-oxopropanoyl-CoA 2-epimerase [incorrect]. Enzyme Commission Number: EC 5.1.99.1. CAS No. 9024-3-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5433; methylmalonyl-CoA epimerase; EC 5.1.99.1; 9024-03-7; methylmalonyl-CoA racemase; methylmalonyl coenzyme A racemase; DL-methylmalonyl-CoA racemase; 2-methyl-3-oxopropanoyl-CoA 2-epimerase [incorrect]. Cat No: EXWM-5433.
methylmalonyl-CoA mutase
Requires a cobamide coenzyme. Group: Enzymes. Synonyms: methylmalonyl-CoA CoA-carbonyl mutase; methylmalonyl coenzyme A mutase; methylmalonyl coenzyme A carbonylmutase; (S)-methylmalonyl-CoA mutase; (R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase [incorrect]. Enzyme Commission Number: EC 5.4.99.2. CAS No. 9023-90-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5559; methylmalonyl-CoA mutase; EC 5.4.99.2; 9023-90-9; methylmalonyl-CoA CoA-carbonyl mutase; methylmalonyl coenzyme A mutase; methylmalonyl coenzyme A carbonylmutase; (S)-methylmalonyl-CoA mutase; (R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase [incorrect]. Cat No: EXWM-5559.
mycocerosate synthase
This mycobacterial enzyme loads long-chain fatty acyl groups from their CoA esters and extends them by incorporation of three or four methylmalonyl (but not malonyl) residues, to form tri- or tetramethyl-branched fatty-acids, respectively, such as 2,4,6,8-tetramethyloctacosanoate (C32-mycocerosate). Since the enzyme lacks a thioesterase domain, the products remain bound to the enzyme and require additional enzyme(s) for removal. Even though the enzyme can accept C6 to C20 substrates in vitro, it prefers to act on C14-C20 substrates in vivo. Group: Enzymes. Synonyms: mas (gene name); mycocerosic acid synthase; acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing). Enzyme Commission Number: EC 2.3.1.111. CAS No. 95229-19-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2050; mycocerosate synthase; EC 2.3.1.111; 95229-19-9; mas (gene name); mycocerosic acid synthase; acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing). Cat No: EXWM-2050.
mycolipanoate synthase
This mycobacterial enzyme accepts long-chain fatty acyl groups from their CoA esters and extends them by incorporation of three methylmalonyl (but not malonyl) residues, forming trimethyl-branched fatty-acids such as (2S,4S,6S)-2,4,6-trimethyltetracosanoate (C27-mycolipanoate). Since the enzyme lacks a thioesterase domain, the product remains bound to the enzyme and requires additional enzyme(s) for removal. Group: Enzymes. Synonyms: msl3 (gene name); Pks3/4; mycolipanoic acid synthase. Enzyme Commission Number: EC 2.3.1.252. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2202; mycolipanoate synthase; EC 2.3.1.252; msl3 (gene name); Pks3/4; mycolipanoic acid synthase. Cat No: EXWM-2202.
oxaloacetate decarboxylase
The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA. The process is accompanied by the extrusion of two sodium ions from cells. Some animal enzymes require Mn2+. Group: Enzymes. Synonyms: oxaloacetate β-decarboxylase; oxalacetic acid decarboxylase; oxalate β-decarboxylase; oxaloacetate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.3. CAS No. 9024-98-0. Oxaloacetate decarboxylase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4773; oxaloacetate decarboxylase; EC 4.1.1.3; 9024-98-0; oxaloacetate β-decarboxylase; oxalacetic acid decarboxylase; oxalate β-decarboxylase; oxaloacetate carboxy-lyase. Cat No: EXWM-4773.
(S)-methylmalonyl-CoA decarboxylase
The enzyme from Veillonella alcalescens is a biotinyl-protein, requires Na+ and acts as a sodium pump. Group: Enzymes. Synonyms: propionyl-CoA carboxylase (incorrect); propionyl coenzyme A carboxylase (incorrect); methylmalonyl-coenzyme A decarboxylase; (S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase (incorrect); (S)-methylmalonyl-CoA carboxy-lyase. Enzyme Commission Number: EC 7.2.4.3 (Formerly EC 4.1.1.41). CAS No. 37289-44-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4786; (S)-methylmalonyl-CoA decarboxylase; EC 4.1.1.41; 37289-44-4; propionyl-CoA carboxylase (incorrect); propionyl coenzyme A carboxylase (incorrect); methylmalonyl-coenzyme A decarboxylase; (S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase (incorrect); (S)-methylmalonyl-CoA carboxy-lyase. Cat No: EXWM-4786.
(S)-methylmalonyl-CoA hydrolase
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is (S)-methylmalonyl-CoA hydrolase. This enzyme is also called D-methylmalonyl-coenzyme A hydrolase. This enzyme participates in propanoate metabolism. Group: Enzymes. Synonyms: D-methylmalonyl-coenzyme A hydrolase. Enzyme Commission Number: EC 3.1.2.17. CAS No. 87928-03-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3551; (S)-methylmalonyl-CoA hydrolase; EC 3.1.2.17; 87928-03-8; D-methylmalonyl-coenzyme A hydrolase. Cat No: EXWM-3551.
Vatiquinone
This active molecular has a para-benzoquinone structure and was developed for inherited mitochondrial diseases base on vitamin E. The mechanism of action of Vatiquinone involves increasing the synthesis of glutathione, optimizing metabolic control and so on. Now it is in Phase I for Gilles de la Tourette's syndrome, in Phase II for Friedreich's ataxia; Methylmalonic acidaemia; Mitochondrial disorders; Noise-induced hearing loss; Parkinson's disease; Rett syndrome Friedreich's ataxia; Methylmalonic acidaemia; Mitochondrial disorders; Noise-induced hearing loss; Parkinson's disease and Rett syndrome, in Phase III for Leigh disease. Uses: Inherited mitochondrial diseases. Synonyms: EPI743; EPI-743; EPI 743; alpha-Tocotrienol quinone;2-[(3R,6E,10E)-3-hydroxy-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl]-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione. Grades: 98%. CAS No. 1213269-98-7. Molecular formula: C29H44O3. Mole weight: 440.67.
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