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A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida shares an NAD(P)H-FMN reductase subunit with EC 1.14.13.179, methylxanthine N3-demethylase, and has a 5-fold higher activity with NADH than with NADPH. Also demethylate 1-methylxantine with lower efficiency. Forms part of the degradation pathway of methylxanthines. Group: Enzymes. Synonyms: ndmA (gene name). Enzyme Commission Number: EC 1.14.13.178. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0776; methylxanthine N1-demethylase; EC 1.14.13.178; ndmA (gene name). Cat No: EXWM-0776.
methylxanthine N3-demethylase
A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida shares an NAD(P)H-FMN reductase subunit with EC 1.14.13.178, methylxanthine N1-demethylase, and has higher activity with NADH than with NADPH. Also demethylates caffeine and theophylline with lower efficiency. Forms part of the degradation pathway of methylxanthines. Group: Enzymes. Synonyms: ndmB (gene name). Enzyme Commission Number: EC 1.14.13.179. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0777; methylxanthine N3-demethylase; EC 1.14.13.179; ndmB (gene name). Cat No: EXWM-0777.
1,3-Dipropyl-7-methylxanthine
A phosphodiesterase inhibitor and caffeine analog with some selectivity for A2 adenosine receptors. UV lmax = 273 nm, log e=3.98. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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1-Methylxanthine
100mg Pack Size. Group: Analytical Reagents, Building Blocks, Organics. Formula: C6H6N4O2. CAS No. 6136-37-4. Prepack ID 56064439-100mg. Molecular Weight 166.14. See USA prepack pricing.
1-Methylxanthine
1g Pack Size. Group: Analytical Reagents, Building Blocks, Organics. Formula: C6H6N4O2. CAS No. 6136-37-4. Prepack ID 56064439-1g. Molecular Weight 166.14. See USA prepack pricing.
1-Methylxanthine
1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) [1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells [2]. Uses: Scientific research. Group: Natural products. CAS No. 6136-37-4. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-W008449.
1-Methylxanthine (2,6-Dihydroxy-1-methylpurine). Group: Biochemicals. Alternative Names: 2,6-Dihydroxy-1-methylpurine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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1-Methylxanthine ≥95% (NMR)
1-Methylxanthine ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. CAS No. 6136-37-4. Pack Sizes: 25mg, 100mg, 250mg, 1g. US Biological Life Sciences.
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3-Isobutyl-1-methylxanthine
3-Isobutyl-1-methylxanthine. Group: Biochemicals. Alternative Names: 3,9-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione; IBMX. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C10H14N4O2. US Biological Life Sciences.
Worldwide
3-Isobutyl-1-methylxanthine (IBMX)
A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC50=2-50uM). Also acts as an adenosine receptor antagonist. Reported to inhibit TNF-a expression in adipocyte precursor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 250mg, 1g. US Biological Life Sciences.
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3-Methylxanthine
3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC 50 of 920 μM on guinea-pig isolated trachealis muscle. Uses: Scientific research. Group: Natural products. CAS No. 1076-22-8. Pack Sizes: 10 mM * 1 mL; 5 g; 25 g; 50 g. Product ID: HY-50723.
3-Methylxanthine
3-Methylxanthine. Group: Biochemicals. Alternative Names: 3,9-Dihydro-3-methyl-1H-purine-2,6-dione; 3,7-Dihydro-3-methyl-1H-purine-2,6-dione;3-Methyl-3,7-dihydro-1H-purine-2,6-dione; 3-Methyl-3,7-dihydropurine-2,6-dione;NSC 515466. Grades: Highly Purified. CAS No. 1076-22-8. Pack Sizes: 1g. Molecular Formula: C6H6N4O2, Molecular Weight: 166.14. US Biological Life Sciences.
Worldwide
3-Methylxanthine
An impurity of Dyphylline which belongs to a class of drugs known as xanthines and is used for reelieving breathing problems caused by bronchial asthma, chronic bronchitis, or emphysema. Synonyms: 3-methyl-7H-purine-2,6-dione. Grades: > 95 %. CAS No. 1076-22-8. Molecular formula: C6H6N4O2. Mole weight: 166.14.
3-Methylxanthine
Heterocyclic Organic Compound. Alternative Names: 2,6-Dihydroxy-3-methylpurine. CAS No. 1076-22-8. Molecular formula: C6H6N4O2. Mole weight: 166.14. Purity: 98%+. Catalog: ACM1076228.
100mg Pack Size. Group: Building Blocks, Organics. Formula: C6H6N4O2. CAS No. 552-62-5. Prepack ID 18393522-100mg. Molecular Weight 166.14. See USA prepack pricing.
7-Methylxanthine
7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 552-62-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W017163.
7-Methylxanthine (2,4,5,6-13C4; 1,3,9-15N3)
Isotope-labeled Metabolites13C 15N Labeled Compounds. Alternative Names: 7-Methylxanthine-13C4,15N3; 7-Methylxanthine-[13C4,15N2]. CAS No. 11730118-93-3. Molecular formula: 13< / sup>C4C2H615< / sup>N3NO2. Mole weight: 173.09. Appearance: White powder. Catalog: ACM11730118933.
7-methylxanthine demethylase
A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida prefers NADH over NADPH. The enzyme is specific for 7-methylxanthine. Forms part of the caffeine degradation pathway. Group: Enzymes. Synonyms: ndmC (gene name). Enzyme Commission Number: EC 1.14.13.128. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0728; 7-methylxanthine demethylase; EC 1.14.13.128; ndmC (gene name). Cat No: EXWM-0728.
8-Bromo-3-methylxanthine 99+% (HPLC)
8-Bromo-3-methylxanthine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 93703-24-3. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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8-Methoxymethyl-3-isobutyl-1-methylxanthine
8-Methoxymethyl-3-isobutyl-1-methylxanthine. Group: Biochemicals. Grades: Reagent Grade. CAS No. 78033-08-6. Pack Sizes: 25mg, 100mg. US Biological Life Sciences.
Worldwide
8-Methylxanthine
8-Methylxanthine. Group: Biochemicals. Alternative Names: 2,6-Dihydroxy-8-methylpurine. Grades: Highly Purified. CAS No. 17338-96-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C6H6N4O2. US Biological Life Sciences.
Worldwide
9-Methylxanthine
100mg Pack Size. Group: Biochemicals, Building Blocks, Organics. Formula: C6H6N4O2. CAS No. 1198-33-0. Prepack ID 55819287-100mg. Molecular Weight 166.14. See USA prepack pricing.
9-Methylxanthine
9-Methylxanthine. Group: Biochemicals. Alternative Names: 2,6-Dihydroxy-9-methylpurine. Grades: Highly Purified. CAS No. 1198-33-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C6H6N4O2. US Biological Life Sciences.
Worldwide
Caffeine (1,3,7 trimethylxanthine)
Caffeine is a naturally occurring chemical that is present in tea, cola nuts, guarana and coffee. It is able to stimulate the central nervous system, cardiac muscle, stimulate the respiratory system, act as a diuretic and delay fatigue. The chemical structure for caffeine is 1,3,7-tri methylxanthine. As a modified purine it can act as an inhibitor of enzymes that use compounds containing adenine or guanine as substrates. Group: Biochemicals. Alternative Names: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione; 1,3,7-Trimethylxanthine; 7-Methyltheophylline; Alert-Pep; Cafalgine; Cafeina; Caffedrine; Caffein; Cafipel; DHCplus; Dasin; Diurex; Durvitan; Guaranine; Hycomine; Koffein; Mateina; Methyltheobromine; Miudol; NSC 5036; New Cetamol; No-Doz; Palergot-C; Phensal; Refresh'n; SK 65 Compound; Shape Plus; Stay Alert; Stim; Synalgos; Thein; Theine; Tri-Aqua; Wigraine. Grades: Highly Purified. CAS No. 58-08-2. Pack Sizes: 25g, 50g, 100g, 500g, 1Kg. US Biological Life Sciences.
Caffeine is a naturally occurring chemical that is present in tea, cola nuts, guarana and coffee. It is able to stimulate the central nervous system, cardiac muscle, stimulate the respiratory system, act as a diuretic and delay fatigue. The chemical structure for caffeine is 1,3,7-tri methylxanthine. As a modified purine it can act as an inhibitor of enzymes that use compounds containing adenine or guanine as substrates. Group: Biochemicals. Alternative Names: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione; 1,3,7-Trimethylxanthine; 7-Methyltheophylline; Alert-Pep; Cafalgine; Cafeina; Caffedrine; Caffein; Cafipel; DHCplus; Dasin; Diurex; Durvitan; Guaranine; Hycomine; Koffein; Mateina; Methyltheobromine; Miudol; NSC 5036; New Cetamol; No-Doz; Palergot-C; Phensal; Refresh'n; SK 65 Compound; Shape Plus; Stay Alert; Stim; Synalgos; Thein; Theine; Tri-Aqua; Wigraine. Grades: USP. CAS No. 58-08-2. Pack Sizes: 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
IBMX (3-Isobutyl-1-methylxanthine)
3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences.
Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity. Group: Biochemicals. Alternative Names: 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 500mg, 1g. US Biological Life Sciences.
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1-Methylcyclopentanol
1-Methylcyclopentanol is used as a reagent in the synthesis of cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV. It is also used in the preparation of Lomifylline (L470200) which is a methylxanthine analog that induces Ca2+-release from intracellular stores via the ryanodine receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1462-03-9. Pack Sizes: 1g, 5g. Molecular Formula: C6H12O. US Biological Life Sciences.
Worldwide
1-Methyl xanthine-d3
Heterocyclic Organic Compound. Alternative Names: 1-METHYLXANTHINE-D3;3,7-Dihydro-1-(methyl-d3)-1H-purine-2,6-dione. CAS No. 109987-37-3. Molecular formula: C6H3D3N4O2. Mole weight: 169.16. Catalog: ACM109987373.
3,4-Didesmethyl Istradefylline
3,4-Didesmethyl Istradefylline is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Synonyms: (E)-8-(3,4-Dihydroxystyryl)-1,3-diethyl-7-methylxanthine; 155272-03-0; 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3,4-dihydroxyphenyl)ethenyl)-7-methyl-, (E)-; 8-[(E)-2-(3,4-DIHYDROXYPHENYL)ETHENYL]-1,3-DIETHYL-7-METHYLPURINE-2,6-DIONE; SCHEMBL7304209; SCHEMBL7304216; GFRYELUTTBEJFS-VQHVLOKHSA-N. CAS No. 155272-03-0. Molecular formula: C18H20N4O4. Mole weight: 356.37.
8-Methoxymethyl-1-methyl-3-(2-methylpropyl) xanthine. Group: Biochemicals. Alternative Names: 3,7-Dihydro-8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione; 8-Methoxymethyl-3-isobutyl-1-methylxanthine; 8-Methoxymethyl-IBMX. Grades: Highly Purified. CAS No. 78033-08-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H18N4O3. US Biological Life Sciences.
Worldwide
A-802715
A802715, a methylxanthine derivative, is an anti-tumor agent with a TD50 (toxic dose of 50%) of 0.9-1.1 mM. Synonyms: 1-(5-hydroxy-5-methylhexyl)-3-methyl-7-propylpurine-2,6-dione; 1-(5-hydroxy-5-methyl)hexyl-3-methyl-7-propylxanthine; A 80 2715; A 802715; A-802715. CAS No. 107767-58-8. Molecular formula: C16H26N4O3. Mole weight: 322.4.
Coffee Seed Extract
Botanical extract obtained from Coffea Arabica (Coffee) seeds. Caffeine content about 100 ppm. Dissolved in water, glycerin, and propanediol. Contains proteins, polysaccharides, methylxanthines, sucrose, lipids, caffeine, trigonelline, and minerals. Uses: Anti-aging & anti-wrinkle serums, creams & lotions, after-sun care, sunscreens, hair color protection products, toners. Group: Skin actives. CAS No. 56-81-5 / 7732-18-5 / 504-63-2 / 84650-00-0 / 532-32-1 / 24634-61-5. Appearance: Clear to slightly turbid, reddish brown liquid, characteristic odor. Catalog: CI-SC-0662.
IBMX
IBMX is an inhibitor of cAMP and cGMP phosphodiesterases. IBMX was shown to promote differentiation of 3T3-L1 cells in combination with insulin and dexamethasone. It also induces neural transdifferentiation of mesenchymal stem cells (MSCs) through downregulation of the NRSF. Uses: Phosphodiesterase inhibitors. Synonyms: 3-Isobutyl-1-methylxanthine; isobutylmethylxanthine; 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione. Grades: >98%. CAS No. 28822-58-4. Molecular formula: C10H14N4O2. Mole weight: 222.24.
Istradefyline
Istradefyline. Group: Biochemicals. Alternative Names: (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine,; 8-[ (1E) -2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-purine-2, 6-dione. Grades: Highly Purified. CAS No. 155270-99-8. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C20H24N4O4. US Biological Life Sciences.
Worldwide
MMPX
MMPX is a specific inhibitor of calmodulin-sensitive cyclic GMP phosphodiesterase (IC50 = 5.2 μM). It causes an increase in cGMP but not cAMP, prolonging signal transduction for cGMP-dependent pathways. Synonyms: 8-Methoxymethyl-3-isobutyl-1-methylxanthine; MMPX; 8-METHOXYMETHYL-1-METHYL-3-(2-METHYLPROPYL)XANTHINE; 8-METHOXYMETHYL-3-ISOBUTYL-1-METHYLXANTHINE; 8-METHOXYMETHYL-3-ISOBUTYRYL-1-METHYLXANTHINE; 8-METHOXYMETHYL-IBMX. CAS No. 78033-08-6. Molecular formula: C12H18N4O3. Mole weight: 266.3.
N-methyl nucleosidase
The enzyme preferentially hydrolyses 3- and 7-methylpurine nucleosides, such as 3-methylxanthosine, 3-methyladenosine and 7-methylguanosine. Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the second step in the caffeine-biosynthesis pathway. Group: Enzymes. Synonyms: 7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase. Enzyme Commission Number: EC 3.2.2.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3979; N-methyl nucleosidase; EC 3.2.2.25; 7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase. Cat No: EXWM-3979.
Proxyphylline
Proxyphylline is a methylxanthine derivative used as a cardiac stimulant, vasodilator and bronchodilator [1]. Uses: Scientific research. Group: Natural products. CAS No. 603-00-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1742.
(R)-Lisofylline
A major metabolite of Pentoxifylline. Methylxanthine that inhibits production of phosphatidic acid during the inflammatory response. Immunomodulator. Group: Biochemicals. Alternative Names: 3,7-Dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-. Grades: Highly Purified. CAS No. 100324-81-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Theobromine
Theobromine is a methylxanthine found in cacao beans which can inhibit adenosine receptor A1 ( AR1 ) signaling. Uses: Scientific research. Group: Natural products. Alternative Names: 3,7-Dimethylxanthine. CAS No. 83-67-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N0138.
theobromine synthase
This is the third enzyme in the caffeine-biosynthesis pathway. This enzyme can also catalyse the conversion of paraxanthine into caffeine, although the paraxanthine pathway is considered to be a minor pathway for caffeine biosynthesis. Group: Enzymes. Synonyms: monomethylxanthine methyltransferase; MXMT; CTS1; CTS2; S-adenosyl-L-methionine:7-methylxanthine 3-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.159. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1755; theobromine synthase; EC 2.1.1.159; monomethylxanthine methyltransferase; MXMT; CTS1; CTS2; S-adenosyl-L-methionine:7-methylxanthine 3-N-methyltransferase. Cat No: EXWM-1755.
Verofylline
Verofylline is used as a methylxanthine bronchodilator. Uses: Verofylline is used as a methylxanthine bronchodilator. Synonyms: CK 0383; CK0383; CK-0383; Verofilina; Verofyllinum; 3,7-Dihydro-1,8-dimethyl-3-(2-methylbutyl)-1H-purine-2,6-dione. Grades: 98%. CAS No. 66172-75-6. Molecular formula: C12H18N4O2. Mole weight: 250.30.
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