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A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida shares an NAD(P)H-FMN reductase subunit with EC 1.14.13.179, methylxanthine N3-demethylase, and has a 5-fold higher activity with NADH than with NADPH. Also demethylate 1-methylxantine with lower efficiency. Forms part of the degradation pathway of methylxanthines. Group: Enzymes. Synonyms: ndmA (gene name). Enzyme Commission Number: EC 1.14.13.178. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0776; methylxanthine N1-demethylase; EC 1.14.13.178; ndmA (gene name). Cat No: EXWM-0776.
methylxanthine N3-demethylase
A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida shares an NAD(P)H-FMN reductase subunit with EC 1.14.13.178, methylxanthine N1-demethylase, and has higher activity with NADH than with NADPH. Also demethylates caffeine and theophylline with lower efficiency. Forms part of the degradation pathway of methylxanthines. Group: Enzymes. Synonyms: ndmB (gene name). Enzyme Commission Number: EC 1.14.13.179. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0777; methylxanthine N3-demethylase; EC 1.14.13.179; ndmB (gene name). Cat No: EXWM-0777.
1,3-Dipropyl-7-methylxanthine
A phosphodiesterase inhibitor and caffeine analog with some selectivity for A2 adenosine receptors. UV lmax = 273 nm, log e=3.98. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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1-Methylxanthine
100mg Pack Size. Group: Analytical Reagents, Building Blocks, Organics. Formula: C6H6N4O2. CAS No. 6136-37-4. Prepack ID 56064439-100mg. Molecular Weight 166.14. See USA prepack pricing.
1-Methylxanthine
1g Pack Size. Group: Analytical Reagents, Building Blocks, Organics. Formula: C6H6N4O2. CAS No. 6136-37-4. Prepack ID 56064439-1g. Molecular Weight 166.14. See USA prepack pricing.
1-Methylxanthine
1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP) [1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells [2]. Uses: Scientific research. Group: Natural products. CAS No. 6136-37-4. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-W008449.
1-Methylxanthine (2,6-Dihydroxy-1-methylpurine)
1-Methylxanthine (2,6-Dihydroxy-1-methylpurine). Group: Biochemicals. Alternative Names: 2,6-Dihydroxy-1-methylpurine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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1-Methylxanthine ≥95% (NMR)
1-Methylxanthine ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. CAS No. 6136-37-4. Pack Sizes: 25mg, 100mg, 250mg, 1g. US Biological Life Sciences.
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3-Isobutyl-1-methylxanthine
3-Isobutyl-1-methylxanthine. Group: Biochemicals. Alternative Names: 3,9-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione; IBMX. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C10H14N4O2. US Biological Life Sciences.
Worldwide
3-Isobutyl-1-methylxanthine (IBMX)
A cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC50=2-50uM). Also acts as an adenosine receptor antagonist. Reported to inhibit TNF-a expression in adipocyte precursor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 250mg, 1g. US Biological Life Sciences.
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3-Methylxanthine
3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC 50 of 920 μM on guinea-pig isolated trachealis muscle. Uses: Scientific research. Group: Natural products. CAS No. 1076-22-8. Pack Sizes: 10 mM * 1 mL; 5 g; 25 g; 50 g. Product ID: HY-50723.
3-Methylxanthine
3-Methylxanthine. Group: Biochemicals. Alternative Names: 3,9-Dihydro-3-methyl-1H-purine-2,6-dione; 3,7-Dihydro-3-methyl-1H-purine-2,6-dione;3-Methyl-3,7-dihydro-1H-purine-2,6-dione; 3-Methyl-3,7-dihydropurine-2,6-dione;NSC 515466. Grades: Highly Purified. CAS No. 1076-22-8. Pack Sizes: 1g. Molecular Formula: C6H6N4O2, Molecular Weight: 166.14. US Biological Life Sciences.
Worldwide
3-Methylxanthine
3-Methylxanthine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,6-Dihydroxy-3-methylpurine. Product Category: Heterocyclic Organic Compound. CAS No. 1076-22-8. Molecular formula: C6H6N4O2. Mole weight: 166.14. Purity: 98%+. Product ID: ACM1076228. Alfa Chemistry ISO 9001:2015 Certified.
3-Methylxanthine
An impurity of Dyphylline which belongs to a class of drugs known as xanthines and is used for reelieving breathing problems caused by bronchial asthma, chronic bronchitis, or emphysema. Synonyms: 3-methyl-7H-purine-2,6-dione. Grades: > 95 %. CAS No. 1076-22-8. Molecular formula: C6H6N4O2. Mole weight: 166.14.
7-Methylxanthine
100mg Pack Size. Group: Building Blocks, Organics. Formula: C6H6N4O2. CAS No. 552-62-5. Prepack ID 18393522-100mg. Molecular Weight 166.14. See USA prepack pricing.
7-Methylxanthine
7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 552-62-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W017163.
7-methylxanthine demethylase
A non-heme iron oxygenase. The enzyme from the bacterium Pseudomonas putida prefers NADH over NADPH. The enzyme is specific for 7-methylxanthine. Forms part of the caffeine degradation pathway. Group: Enzymes. Synonyms: ndmC (gene name). Enzyme Commission Number: EC 1.14.13.128. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0728; 7-methylxanthine demethylase; EC 1.14.13.128; ndmC (gene name). Cat No: EXWM-0728.
8-Bromo-3-methylxanthine 99+% (HPLC)
8-Bromo-3-methylxanthine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 93703-24-3. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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8-Methoxymethyl-3-isobutyl-1-methylxanthine
8-Methoxymethyl-3-isobutyl-1-methylxanthine. Group: Biochemicals. Grades: Reagent Grade. CAS No. 78033-08-6. Pack Sizes: 25mg, 100mg. US Biological Life Sciences.
Worldwide
8-Methylxanthine
8-Methylxanthine. Group: Biochemicals. Alternative Names: 2,6-Dihydroxy-8-methylpurine. Grades: Highly Purified. CAS No. 17338-96-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C6H6N4O2. US Biological Life Sciences.
Worldwide
9-Methylxanthine
100mg Pack Size. Group: Biochemicals, Building Blocks, Organics. Formula: C6H6N4O2. CAS No. 1198-33-0. Prepack ID 55819287-100mg. Molecular Weight 166.14. See USA prepack pricing.
9-Methylxanthine
9-Methylxanthine. Group: Biochemicals. Alternative Names: 2,6-Dihydroxy-9-methylpurine. Grades: Highly Purified. CAS No. 1198-33-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C6H6N4O2. US Biological Life Sciences.
Worldwide
Caffeine (1,3,7 trimethylxanthine)
Caffeine is a naturally occurring chemical that is present in tea, cola nuts, guarana and coffee. It is able to stimulate the central nervous system, cardiac muscle, stimulate the respiratory system, act as a diuretic and delay fatigue. The chemical structure for caffeine is 1,3,7-tri methylxanthine. As a modified purine it can act as an inhibitor of enzymes that use compounds containing adenine or guanine as substrates. Group: Biochemicals. Alternative Names: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione; 1,3,7-Trimethylxanthine; 7-Methyltheophylline; Alert-Pep; Cafalgine; Cafeina; Caffedrine; Caffein; Cafipel; DHCplus; Dasin; Diurex; Durvitan; Guaranine; Hycomine; Koffein; Mateina; Methyltheobromine; Miudol; NSC 5036; New Cetamol; No-Doz; Palergot-C; Phensal; Refresh'n; SK 65 Compound; Shape Plus; Stay Alert; Stim; Synalgos; Thein; Theine; Tri-Aqua; Wigraine. Grades: Highly Purified. CAS No. 58-08-2. Pack Sizes: 25g, 50g, 100g, 500g, 1Kg. US Biological Life Sciences.
Caffeine is a naturally occurring chemical that is present in tea, cola nuts, guarana and coffee. It is able to stimulate the central nervous system, cardiac muscle, stimulate the respiratory system, act as a diuretic and delay fatigue. The chemical structure for caffeine is 1,3,7-tri methylxanthine. As a modified purine it can act as an inhibitor of enzymes that use compounds containing adenine or guanine as substrates. Group: Biochemicals. Alternative Names: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione; 1,3,7-Trimethylxanthine; 7-Methyltheophylline; Alert-Pep; Cafalgine; Cafeina; Caffedrine; Caffein; Cafipel; DHCplus; Dasin; Diurex; Durvitan; Guaranine; Hycomine; Koffein; Mateina; Methyltheobromine; Miudol; NSC 5036; New Cetamol; No-Doz; Palergot-C; Phensal; Refresh'n; SK 65 Compound; Shape Plus; Stay Alert; Stim; Synalgos; Thein; Theine; Tri-Aqua; Wigraine. Grades: USP. CAS No. 58-08-2. Pack Sizes: 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
IBMX (3-Isobutyl-1-methylxanthine)
3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences.
Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity. Group: Biochemicals. Alternative Names: 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 500mg, 1g. US Biological Life Sciences.
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1-Methylcyclopentanol
1-Methylcyclopentanol is used as a reagent in the synthesis of cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV. It is also used in the preparation of Lomifylline (L470200) which is a methylxanthine analog that induces Ca2+-release from intracellular stores via the ryanodine receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1462-03-9. Pack Sizes: 1g, 5g. Molecular Formula: C6H12O. US Biological Life Sciences.
Worldwide
3,4-Didesmethyl Istradefylline
3,4-Didesmethyl Istradefylline is one of Istradefylline impurities, a selective A(2A) antagonist used in the treatment of Parkinson's disease. Synonyms: (E)-8-(3,4-Dihydroxystyryl)-1,3-diethyl-7-methylxanthine; 155272-03-0; 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3,4-dihydroxyphenyl)ethenyl)-7-methyl-, (E)-; 8-[(E)-2-(3,4-DIHYDROXYPHENYL)ETHENYL]-1,3-DIETHYL-7-METHYLPURINE-2,6-DIONE; SCHEMBL7304209; SCHEMBL7304216; GFRYELUTTBEJFS-VQHVLOKHSA-N. CAS No. 155272-03-0. Molecular formula: C18H20N4O4. Mole weight: 356.37.
8-Methoxymethyl-1-methyl-3-(2-methylpropyl) xanthine. Group: Biochemicals. Alternative Names: 3,7-Dihydro-8-(methoxymethyl)-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione; 8-Methoxymethyl-3-isobutyl-1-methylxanthine; 8-Methoxymethyl-IBMX. Grades: Highly Purified. CAS No. 78033-08-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H18N4O3. US Biological Life Sciences.
Worldwide
A-802715
A802715, a methylxanthine derivative, is an anti-tumor agent with a TD50 (toxic dose of 50%) of 0.9-1.1 mM. Synonyms: 1-(5-hydroxy-5-methylhexyl)-3-methyl-7-propylpurine-2,6-dione; 1-(5-hydroxy-5-methyl)hexyl-3-methyl-7-propylxanthine; A 80 2715; A 802715; A-802715. CAS No. 107767-58-8. Molecular formula: C16H26N4O3. Mole weight: 322.4.
IBMX
IBMX is an inhibitor of cAMP and cGMP phosphodiesterases. IBMX was shown to promote differentiation of 3T3-L1 cells in combination with insulin and dexamethasone. It also induces neural transdifferentiation of mesenchymal stem cells (MSCs) through downregulation of the NRSF. Uses: Phosphodiesterase inhibitors. Synonyms: 3-Isobutyl-1-methylxanthine; isobutylmethylxanthine; 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione. Grades: >98%. CAS No. 28822-58-4. Molecular formula: C10H14N4O2. Mole weight: 222.24.
Istradefyline
Istradefyline. Group: Biochemicals. Alternative Names: (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine,; 8-[ (1E) -2- (3, 4-Dimethoxyphenyl) ethenyl]-1, 3-diethyl-3, 7-dihydro-7-methyl-1H-purine-2, 6-dione. Grades: Highly Purified. CAS No. 155270-99-8. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C20H24N4O4. US Biological Life Sciences.
Worldwide
MMPX
MMPX is a specific inhibitor of calmodulin-sensitive cyclic GMP phosphodiesterase (IC50 = 5.2 μM). It causes an increase in cGMP but not cAMP, prolonging signal transduction for cGMP-dependent pathways. Synonyms: 8-Methoxymethyl-3-isobutyl-1-methylxanthine; MMPX; 8-METHOXYMETHYL-1-METHYL-3-(2-METHYLPROPYL)XANTHINE; 8-METHOXYMETHYL-3-ISOBUTYL-1-METHYLXANTHINE; 8-METHOXYMETHYL-3-ISOBUTYRYL-1-METHYLXANTHINE; 8-METHOXYMETHYL-IBMX. CAS No. 78033-08-6. Molecular formula: C12H18N4O3. Mole weight: 266.3.
N-methyl nucleosidase
The enzyme preferentially hydrolyses 3- and 7-methylpurine nucleosides, such as 3-methylxanthosine, 3-methyladenosine and 7-methylguanosine. Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the second step in the caffeine-biosynthesis pathway. Group: Enzymes. Synonyms: 7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase. Enzyme Commission Number: EC 3.2.2.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3979; N-methyl nucleosidase; EC 3.2.2.25; 7-methylxanthosine nucleosidase; N-MeNase; N-methyl nucleoside hydrolase; methylpurine nucleosidase. Cat No: EXWM-3979.
Proxyphylline
Proxyphylline is a methylxanthine derivative used as a cardiac stimulant, vasodilator and bronchodilator [1]. Uses: Scientific research. Group: Natural products. CAS No. 603-00-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1742.
(R)-Lisofylline
A major metabolite of Pentoxifylline. Methylxanthine that inhibits production of phosphatidic acid during the inflammatory response. Immunomodulator. Group: Biochemicals. Alternative Names: 3,7-Dihydro-1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-. Grades: Highly Purified. CAS No. 100324-81-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Theobromine
Theobromine is a methylxanthine found in cacao beans which can inhibit adenosine receptor A1 ( AR1 ) signaling. Uses: Scientific research. Group: Natural products. Alternative Names: 3,7-Dimethylxanthine. CAS No. 83-67-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N0138.
theobromine synthase
This is the third enzyme in the caffeine-biosynthesis pathway. This enzyme can also catalyse the conversion of paraxanthine into caffeine, although the paraxanthine pathway is considered to be a minor pathway for caffeine biosynthesis. Group: Enzymes. Synonyms: monomethylxanthine methyltransferase; MXMT; CTS1; CTS2; S-adenosyl-L-methionine:7-methylxanthine 3-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.159. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1755; theobromine synthase; EC 2.1.1.159; monomethylxanthine methyltransferase; MXMT; CTS1; CTS2; S-adenosyl-L-methionine:7-methylxanthine 3-N-methyltransferase. Cat No: EXWM-1755.
Verofylline
Verofylline is used as a methylxanthine bronchodilator. Uses: Verofylline is used as a methylxanthine bronchodilator. Synonyms: CK 0383; CK0383; CK-0383; Verofilina; Verofyllinum; 3,7-Dihydro-1,8-dimethyl-3-(2-methylbutyl)-1H-purine-2,6-dione. Grades: 98%. CAS No. 66172-75-6. Molecular formula: C12H18N4O2. Mole weight: 250.30.
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