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100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C31H43NO7. CAS No. 129496-10-2. Prepack ID 56079360-100mg. Molecular Weight 1097.38. See USA prepack pricing.
Milbemycinoxime
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C31H43NO7. CAS No. 129496-10-2. Prepack ID 56079360-1g. Molecular Weight 1097.38. See USA prepack pricing.
Milbemycinoxime
Milbemycinoxime is a macrocyclic lactone and has broad-spectrum anti-parasitic activity. Milbemycinoxime is composed of milbemycins A4 and A3. Milbemycinoxime binds glutamate-gated chloride channels. Milbemycinoxime is against intestinal nematodes, pulmonary and cardiac helminths. Group: Inhibitors. Alternative Names: Milbemycinoxime;MilbemycinOxime (200 mg). CAS No. 129496-10-2. Molecular formula: 2C32H45NO7.2C31H43NO7. Mole weight: 2194.78. Purity: 0.9982. Catalog: ACM129496102.
Milbemycinoxime
Milbemycinoxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycinoxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycinoxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 129496-10-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0778.
Milbemycinoxime
Milbemycinoxime is a semi-synthetic macrolide. As a nematocide and insecticide in veterinary medicine, it opens glutamate sensitive chloride channels in neurons of invertebrates that leads to paralysis by hyperpolarisation of these cells and signal transfer blocking. M1-family aminopeptidase: IC50=2.6 μM (Plasmodium falciparum 3D7); Bile acid transporter: IC50=3.6 μM (human); TGR5: IC50=36.4 μM (human); HCT-116: IC50 >50 μM (human); GBM: IC50 >50 μM (human). Uses: A broad spectrum insecticide; used for treatment and prevention of heartworm in dogs and cats. Synonyms: Milbemycin A 5-oxime; Milbemite; Trifexis; Interceptor; Milbe Mite. Grades: ≥98%. CAS No. 129496-10-2. Molecular formula: C126H176N4O28. Mole weight: 2194.78.
MilbemycinOxime
Milbemycinoxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4 (in ~70: 30 ratio). Moxidectin oxime, marketed as Interceptor, is used therapeutically for the prevention of intestinal parasites in dogs. Like the other milbemycin / avermectins, it was developed for intestinal parasite control in animals and acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking. Group: Biochemicals. Grades: Highly Purified. CAS No. 129496-10-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
MilbemycinOxime (Mixture of MilbemycinOxime A3 and MilbemycinOxime A4, 80:20)
MilbemycinOxime can potentiate glutamate and GABA-gated chloride-channel opening and is used as a nematocide and insecticide in veterinary medicine. Group: Biochemicals. Grades: Highly Purified. CAS No. 129496-10-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C31H43NO7 (A3:80%) and C32H45NO7 (A4:20%). US Biological Life Sciences.
Worldwide
apo-Milbemycin A3 oxime
apo-Milbemycin A4 oxime
Milbemycin A3 oxime
Milbemycin A3 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of milbemycin A3. Milbemycin A3 oxime is the minor component of the anti-parasitic product milbemycinoxime. Synonyms: 5-Oxomilbemycin A3 oxime; (6R,25R)-5-Demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methylmilbemycin B. Grades: >95%. CAS No. 114177-14-9. Molecular formula: C31H43NO7. Mole weight: 541.67.
Milbemycin A4 oxime
Milbemycin A4 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of milbemycin A4. Milbemycin A4 oxime is the major component (70%) in the commercial product, milbemycinoxime. Synonyms: 5-Oxomilbemycin A4 oxime. Grades: >95%. CAS No. 93074-04-5. Molecular formula: C32H45NO7. Mole weight: 555.70.
Afoxolaner
Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies. It is administered orally in meat-flavoured tablets, and poisons fleas once they start feeding. It is used either alone or as a combination treatment with milbemycinoxime. Synonyms: 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; 4-[5-[3-Chloro-5- (trifluoromethyl) phenyl]-5- (trifluoromethyl) -4H-1, 2-oxazol-3-yl]-N-[2-oxo-2- (2, 2, 2-trifluoroethylamino) ethyl]naphthalene-1-carboxamide. Grades: >98%. CAS No. 1093861-60-9. Molecular formula: C26H17ClF9N3O3. Mole weight: 625.87.
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