Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Mitoxantrone | 50mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6. CAS No. 65271-80-9. Prepack ID 28035650-50mg. Molecular Weight 444.48. See USA prepack pricing. |  |
| Mitoxantrone | Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; 1, 4-Bis [ (2- (2- hydroxyethylamino) ethyl) amino] -5, 8-di hydroxyanthraquinone. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Mitoxantrone | Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity [1] [2] [3] [4]. Mitoxantrone also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone; NSC 301739. CAS No. 65271-80-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502. |  |
| Mitoxantrone (1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione) | An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. | Worldwide |
| Mitoxantrone (2-hydroxyethyl) piperazine impurity(mitoxantrone impurity D) | Mitoxantrone (2-hydroxyethyl) piperazine impurity(mitoxantrone impurity D). Group: Biochemicals. Alternative Names: 1, 2, 3, 4-Tetrahydro-8, 11-dihydroxy-4- (2-hydroxyethyl) -6- [ [2- [ (2-hydroxyethyl) amino] ethyl] amino] naphtho [2, 3-f] quinoxaline-7, 12-dione; Mitoxantrone impurity D. Grades: Highly Purified. CAS No. 137132-70-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C22H26N4O6. US Biological Life Sciences. | Worldwide |
| Mitoxantrone (2-Hydroxyethyl) piperazine Impurity (Mitoxantrone Impurity D) | A metabolite of the anticancer agent Mitoxantrone. Group: Biochemicals. Alternative Names: 1, 2, 3, 4-Tetrahydro-8, 11-dihydroxy-4- (2-hydroxyethyl) -6- [ [2- [ (2-hydroxyethyl) amino] ethyl] amino] naphtho [2, 3-f] quinoxaline-7, 12-dione; Mitoxantrone Impurity D. Grades: Highly Purified. CAS No. 137132-70-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Mitoxantrone-d8 (1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione-d8) | A DNA intercalating drug. Inhibits DNA synthesis. Used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Mitoxantrone dihydrochloride | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6 · 2HCl. CAS No. 70476-82-3. Prepack ID 24343907-1g. Molecular Weight 517.4. See USA prepack pricing. | |
| Mitoxantrone dihydrochloride | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Mitoxantrone dihydrochloride | It is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating and antineoplastic anthraquinone derivative. Synonyms: 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione dihydrochloride; DHAQ; CL-232325; CL 232325; CL232325; Novantrone; Mitroxone; Neotalem; Onkotrone; Pralifan; Mitoxantrone 2HCl; Immunex. Grade: >98%. CAS No. 70476-82-3. Molecular formula: C22H28N4O6.2HCl. Mole weight: 517.40. |  |
| Mitoxantrone dihydrochloride | Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity [1] [2] [3] [4]. Mitoxantrone dihydrochloride also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride. CAS No. 70476-82-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502A. | |
| Mitoxantrone Dihydrochloride | Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione Hydrochloride; Bisantrone; CL 232315; DHAD; Immunex; Mitoxantrone Hydrochloride; NCI 301739; NSC 301739; Novantron; Novantrone; Novatrone. Grades: Highly Purified. CAS No. 70476-82-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Mitoxantrone hydrochloride | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dione dihydrochloride,Mitoxantrone hydrochloride. | |
| Mitoxantrone Impurity4 | Mitoxantrone Impurity4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 100204-25-9. Molecular formula: C24H28ClF3N4O7. Mole weight: 576.95. Catalog: APB100204259. | |
| Mitoxantrone Liposome | Mitoxantrone is an anthracycline that enters the nucleus of the cell and binds to DNA, thereby inhibiting nucleic acid synthesis and mitosis, leading to cell death. This product is a pre-formulated liposome with mitoxantrone. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. |  |
| Mitoxantrone System Suitability Mixture | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| 1-Deshydroxy Mitoxantrone | 1-Deshydroxy Mitoxantrone. Group: Biochemicals. Alternative Names: 4-Hydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; 1-Deshydroxy DHAQ; Dihydroxyanthraquinone 1-Deshydroxy; Mitox 1-Deshydroxy; Mitoxanthrone 1-Deshydroxy; Mitozantrone 1-Deshydroxy; Nimitoxantron 1-Deshydroxy; Novantron 1-Deshydroxy; Novantrone 1-Deshydroxy; Ralenova 1-Deshydroxy; NSC 279836 1-Deshydroxy; Mitoxantrone Impurity B. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C22H28N4O5, Molecular Weight: 428.48. US Biological Life Sciences. | Worldwide |
| 1-Fluoro-1-des[2-[ (2-Hydroxyethyl) amino]ethylamino] Mitoxantrone | Mitoxantrone derivative, used in the preparation of Mitoxantrone analogues useful as stem-loop structure stabilizing ligand. Group: Biochemicals. Alternative Names: 1-Fluoro-5, 8-dihydroxy-4-[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione. Grades: Highly Purified. CAS No. 1195810-93-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 3-Chloro Mitoxantrone | 3-Chloro Mitoxantrone. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-3-chloro-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; 3-Chloro DHAQ; 3-Chloro Di hydroxyanthraquinone; 3-Chloro Mitox; 3-Chloro Mitoxanthrone; 3-Chloro Mitozantrone; 3-Chloro Nimitoxantron; 3-Chloro Novantron; 3-Chloro Novantrone; 3-Chloro Ralenova; NSC 279836; Mitoxantrone Impurity C. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C22H27ClN4O6, Molecular Weight: 478.93. US Biological Life Sciences. | Worldwide |
| Des[2-[ (2-hydroxyethyl) amino]ethyl] mitoxantrone (mitoxantrone impurity A) | Des[2-[ (2-hydroxyethyl) amino]ethyl] mitoxantrone (mitoxantrone impurity A). Group: Biochemicals. Alternative Names: 1-Amino-5, 8-dihydroxy-4-[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; Mitoxantrone impurity A. Grades: Highly Purified. CAS No. 89991-52-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C18H19N3O5. US Biological Life Sciences. | Worldwide |
| Des[2-[ (2-Hydroxyethyl) amino]ethyl] Mitoxantrone (Mitoxantrone Impurity A) | An impurity of the anticancer agent Mitoxantrone used in immunosuppresion studies. Group: Biochemicals. Alternative Names: 1-Amino-5, 8-dihydroxy-4-[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; Mitoxantrone Impurity A. Grades: Highly Purified. CAS No. 89991-52-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1, 4-Dihydroxy-5, 8-bis[2- (2-hydroxyethylamino) ethylamino]-anthracene-9, 10-dione | 1, 4-Dihydroxy-5, 8-bis[2- (2-hydroxyethylamino) ethylamino]-anthracene-9, 10-dione. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; DHAQ; NSC-279836; Mitoxantrone. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C22H28N4O6. US Biological Life Sciences. | Worldwide |
| 2- (2-Aminoethylamino) ethanol-d4 | Intermediate in the production of labeled Mitoxantrone. Group: Biochemicals. Alternative Names: (2-Hydroxyethyl) ethylenediamine-d4; ( β -Hydroxyethyl) ethylenediamine-d4; 1-(2-Hydroxyethylamino)-2-aminoethane-d4; 1-Aminooxyethylamine-d4; Amino Alcohol EA-d4; Aminoethylethanolamine-d4; N-(2-Hydroxyethyl)-1,2-diaminoethane-d4; N-(2-Hydroxyethyl)-1,2-ethanediamine-d4; NSC 461-d4. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-(2-Aminoethylamino)ethanol-[d4] | 2-(2-Aminoethylamino)ethanol-[d4] is the labelled analogue of 2-(2-Aminoethylamino)ethanol, which is an intermediate in the production of Mitoxantrone. Synonyms: 2-(2-Aminoethylamino)ethanol-d4; Amino Alcohol EA-d4; 1-Aminooxyethylamine-d4; Aminoethylethanolamine-d4; NSC 461-d4; (2-Hydroxyethyl)ethylenediamine-d4. Grade: 95% by HPLC; 98% atom D. CAS No. 1246819-88-4. Molecular formula: C4H8D4N2O. Mole weight: 108.18. | |
| 2-(4-Methoxy-3-methylbenzoyl)benzoic Acid | 2-(4-Methoxy-3-methylbenzoyl)benzoic Acid is an intermediate in synthesizing 2-Hydroxy-3-methylanthraquinone (H946680), a derivative of anthraquinone (A679245) which is an important precursor for many drugs, including Emodin (E523000), Aloe-emodin (A575400), Antimalarials such as Rufgallol, and also Antineoplastics used in the treatment of cancer, such as mitoxantrone (M373425), pixantrone (P552500), and the anthracyclines. Group: Biochemicals. Grades: Highly Purified. CAS No. 51671-71-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H14O4. US Biological Life Sciences. | Worldwide |
| 2-Fluoroadenosine | Fludarabine is highly effective in the treatment of chronic lymphocytic leukemia, producing higher response rates than alkylating agents such as chlorambucil alone.Fludarabine is used in various combinations with cyclophosphamide, mitoxantrone, dexamethasone and rituximab in the treatment of indolent non-Hodgkins lymphomas. As part of the FLAG regimen, fludarabine is used together with cytarabine and granulocyte colony-stimulating factor in the treatment of acute myeloid leukaemia. Because of its immunosuppressive effects, fludarabine is also used in some conditioning regimens prior to non myeloablative allogeneic stem cell transplant. Synonyms: Fludarabine; 2-Fluoro Adenosine; 6-Amino-2-fluoro-9-beta-D-ribofuranosylpurine. Grade: 98%. CAS No. 146-78-1. Molecular formula: C10H12FN5O4. Mole weight: 285.235. | |
| 2-Hydroxy-1-methyl-9,10-anthracenedione | 2-Hydroxy-1-methyl-9,10-anthracenedione is an intermediate in synthesizing 2-Hydroxy-3-methylanthraquinone (H946680), a derivative of anthraquinone (A679245) which is an important precursor for many drugs, including Emodin (E523000), Aloe-emodin (A575400), Antimalarials such as Rufgallol, and also Antineoplastics used in the treatment of cancer, such as mitoxantrone (M373425), pixantrone (P552500), and the anthracyclines. Group: Biochemicals. Grades: Highly Purified. CAS No. 5025-12-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C15H10O3. US Biological Life Sciences. | Worldwide |
| 2-Hydroxy-3-methylanthraquinone | 2-Hydroxy-3-methylanthraquinone is a derivative of anthraquinone (A679245) which is an important precursor for many drugs, including Emodin (E523000), Aloe-emodin (A575400), Antimalarials such as Rufgallol, and also Antineoplastics used in the treatment of cancer, such as mitoxantrone (M373425), pixantrone (P552500), and the anthracyclines. Group: Biochemicals. Grades: Highly Purified. CAS No. 17241-40-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C15H10O3. US Biological Life Sciences. | Worldwide |
| Cholesteryl sulfate sodium | Cholesteryl sulfate sodium is an orally available, NPC2 -targeted cholesterol biosynthesis agonist. Cholesteryl sulfate sodium activates SREBP2 by competitively binding to NPC2, promoting cholesterol synthesis ( EC 50 =50 μM). Cholesteryl sulfate sodium enhances the self-assembly ability of Mitoxantrone hydrochloride (HY-13502A), while repairing the intestinal mucosal barrier and inhibiting inflammation by regulating serine protease activity and PKCη signaling pathway. Cholesteryl sulfate sodium is a component of the platelet cell membrane and supports platelet adhesion. Cholesteryl sulfate sodium also regulates the activity of selective protein kinase C isoforms and modulates the specificity of PI3K, playing a role in keratinocyte differentiation [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2864-50-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111355B. | |
| Ethonafide | Ethonafide is an anthracene-containing derivative of amonafide that belongs to the azonafide series of anticancer agents. The lack of cross-resistance in multidrug-resistant cancer cell lines and the absence of a quinone and hydroquinone moiety make ethonafide a potentially less cardiotoxic replacement for existing anthracene-containing anticancer agents. Ethonafide was cytotoxic against three human prostate cancer cell lines at nanomolar concentrations. Ethonafide was found to be better tolerated and more effective at inhibiting tumor growth compared with mitoxantrone in a human xenograft tumor regression mouse model. Mechanistically, we found that ethonafide inhibited topoisomerase II activity by stabilizing the enzyme-DNA complex, involving both topoisomerase IIalpha and -beta. In addition, ethonafide induced a potent G(2) cell cycle arrest in the DU 145 human prostate cancer cell line. By creating stable cell lines with decreased expression of topoisomerase IIalpha or -beta, we found that a decrease in topoisomerase IIalpha protein expression renders the cell line resistant to ethonafide. The decrease in sensitivity to ethonafide was associated with a decrease in DNA damage and an increase in DNA repair as measured by the neutral comet assay. These data demonstrate that ethonafide is a topoisomerase II poison and that it is topoisomerase IIalpha-specific in the DU 145 human prostate cancer cell line. Uses: Topoisomerase ii | |
Our database is helping our users find suppliers everyday.
