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| Product | Description | |
|---|---|---|
| ML 190 | ML 190. Group: Biochemicals. Grades: Purified. CAS No. 1355244-02-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ML 190 | ML 190 is a κ opioid receptor antagonist with IC50 value of 120 nM. Synonyms: ML 190; ML190; ML-190; N-[3-[4-(4-Methoxyphenyl)-1-piperazinyl]propyl]-1-methyl-6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazine-5(6H)-acetamide. Grades: ≥98% by HPLC. CAS No. 1355244-02-8. Molecular formula: C27H32N6O3. Mole weight: 488.58. |  |
| 1-Methyl-1H-pyrazol-3-amine | 1-Methyl-1H-pyrazol-3-amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1904-31-0. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-76189. |  |
| (4-Nitrophenoxy)acetic acid ethyl ester | (4-Nitrophenoxy)acetic acid ethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Oprea1_542806, MLS000564015, ethyl (4-nitrophenoxy)acetate, MolPort-000-655-965, NSC211067, CID308938, STK400579, ZINC00078019, (4-Nitro-phenoxy)-acetic acid ethyl ester, BAS 00681590, SMR000175845, EU-0034658, 3Z-0931, 19076-89-2. Product Category: Heterocyclic Organic Compound. CAS No. 19076-89-2. Molecular formula: C10H11NO5. Mole weight: 225.2. Purity: 0.96. IUPACName: ethyl 2-(4-nitrophenoxy)acetate. Canonical SMILES: CCOC(=O)COC1=CC=C(C=C1)[N+](=O)[O-]. Density: 1.263g/cm³. Product ID: ACM19076892. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 7-Hydroxy-4-methyl-8-nitrocoumarin | 7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19037-69-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N6657. | |
| Actinonin | Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M , aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a K i of 0.28 nM. Actinonin also inhibits MMP-1 , MMP-3 , MMP-8 , MMP-9 , and hmeprin α with K i values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Actinonin. CAS No. 13434-13-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113952. | |
| Altechromone A | Altechromone A is produced from Alternaria brassicicola ML-P08. Altechromone A shows antimicrobial activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively. Synonyms: 7-Hydroxy-2,5-dimethylchromone; 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one. Grades: 98.0%. CAS No. 38412-47-4. Molecular formula: C11H10O3. Mole weight: 190.19. | |
| Avutometinib | Avutometinib (Ro 5126766) is a first-in-class dual MEK / RAF inhibitor that allosterically inhibits BRAF V600E , CRAF , MEK , and BRAF (IC 50 : 8.2, 56, 160 nM, and 190 nM, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 5126766; CH5126766. CAS No. 946128-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18652. | |
| Bepotastine besilate | Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 190786-44-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-A0015. | |
| BMS-599626 Hydrochloride | BMS-599626 Hydrochloride (AC480 Hydrochloride) is a selective and orally bioavailable HER1 and HER2 inhibitor, with IC 50 s of 20 and 30 nM, respectively. BMS-599626 Hydrochloride displays ~8-fold less potent to HER4 (IC 50=190 nM), >100-fold to VEGFR2, c-Kit, Lck, MEK. BMS-599626 Hydrochloride inhibits tumor cell proliferation, and has potential to increase tumor response to radiotherapy [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AC480 Hydrochloride. CAS No. 873837-23-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12010. | |
| Cholesterol absorption inhibitor 1 | Cholesterol absorption inhibitor 1 (compound 21) is a cholesterol absorption inhibitor that reduces liver cholesteryl ester [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 190595-65-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-45131. | |
| Danicopan | Danicopan (ACH-4471), a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with K d value of 0.54 nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACH-4471. CAS No. 1903768-17-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117930. | |
| Dioscin | Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Collettiside III; CCRIS 4123. CAS No. 19057-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0124. | |
| EC23 | EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 190205; BASF-46928. CAS No. 104561-41-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12309. | |
| Ethyl Alcohol, completely denatured, 190 proof | Ethyl Alcohol, completely denatured, 190 proof. Grades: 95.% Very High (95-98%). CAS No. 64-17-5. Pack Sizes: Milliliter Quantities: 500 ml, 4 L, 4 x 4 L, 20 L. Order Number: 55200. |  www.prochemonline.com |
| Filapixant | Filapixant is a purinoreceptor antagonist extracted from patent WO2016091776A1, example 348. Filapixant is the active reference substance of Eliapixant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1902607. CAS No. 1948232-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109173. | |
| GW3965 hydrochloride | GW3965 hydrochloride is a potent and selective liver X receptor (LXR) agonist with EC 50 s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 405911-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10627A. | |
| Lasofoxifene tartrate | Lasofoxifene (CP-336156) tartrate is an orally active and selective estrogen receptor modulator ( SERM ) [1]. Lasofoxifene tartrate exhibits an anti-osteoporotic function and also inhibits primary tumor growth and metastases. Lasofoxifene tartrate can be used for the research of breast cancer and postmenopausal osteoporosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-336156 tartrate. CAS No. 190791-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-A0038. | |
| MG-101 | MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K i s of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain inhibitor I; Ac-LLnL-CHO; ALLN. CAS No. 110044-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18964. | |
| ML 382 | ML 382 is an allosteric modulator of MrgX1 with EC50 value of 190 nM. Synonyms: ML382; ML-382; ML 382; 2-[(Cyclopropylsulfonyl)amino]-N-(2-ethoxyphenyl)benzamide. Grades: ≥98% by HPLC. CAS No. 1646499-97-9. Molecular formula: C18H20N2O4S. Mole weight: 360.43. | |
| N-(1-Adamantyl)benzamide | N-(1-Adamantyl)benzamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(1-Adamantyl)benzamide, N-(adamantan-1-yl)benzamide, BENZAMIDE, N-1-ADAMANTYL-, BRN 2809387, F0832-0196, 19026-84-7, AC1Q5LRY, CBMicro_049122, AC1L1HC5, AC1Q59ZK, N1-(1-adamantyl)benzamide, N-Adamantan-1-yl-benzamide, SureCN1421026, Oprea1_369566, Oprea1_457459, Oprea1_476630, MLS000693007, CTK8H4160, MolPort-001-798-419, MolPort-001-820-003. Product Category: Heterocyclic Organic Compound. CAS No. 19026-84-7. Molecular formula: C17H21NO. Mole weight: 255.355 g/mol. Purity: 0.96. IUPACName: N-(1-adamantyl)benzamide. Canonical SMILES: C1C2CC3CC1CC(C2)(C3)NC(=O)C4=CC=CC=C4. Density: 1.15g/cm³. Product ID: ACM19026847. Alfa Chemistry ISO 9001:2015 Certified. | |
| (+)-Norfenfluramine | (+)-Norfenfluramine a major hepatic metabolite of (+)-fenfluramine, is a selective 5-HT 2B receptor agonist ( K i : 11.2 nM). (+)-Norfenfluramine potently stimulates the hydrolysis of inositol phosphates and increases intracellular Ca 2+. (+)-Norfenfluramine can be used for the research of primary pulmonary hypertension and valvular heart disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19036-73-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W131725. | |
| Oryzalin | Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19044-88-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-147092. | |
| RO3201195 | RO3201195 (compound 1) is an inhibitor of p38 MAPK. RO3201195 inhibits WS cell proliferation with IC 50 value of 190 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 249937-52-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-118612. | |
| Sisunatovir | Sisunatovir (RV521), an orally available inhibitor of the RSV protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC 50 s of 1.4 nM and 1.0 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RV521. CAS No. 1903763-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123475. | |
| Sisunatovir hydrochloride | Sisunatovir (RV521) hydrochloride, an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC 50 s of 1.4?nM and 1.0?nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RV521 hydrochloride. CAS No. 1903763-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123475A. | |
| Tazarotene | Tazarotene (AGN 190168) is a selective retinoic acid receptor ( RAR ) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 190168. CAS No. 118292-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15388. | |
| Tazarotenic acid | Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 190299. CAS No. 118292-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101108. | |
| (-)-TK216 | (-)-TK216 is an enantiomer of TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor. (-)-TK216 has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1903783-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122903A. | |
| (+)-TK216 | (+)-TK216 is an enantiomer of TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1903783-77-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122903B. | |
| XMD8-92 | XMD8-92 is a potent ERK5 (BMK1)/BRD4 inhibitor with K d s of 80 and 190 nM, respectively. XMD8-92 inhibits DCAMKL2, PLK4 and TNK1 with K d s of 190, 600 and 890 nM, respectively. Anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1234480-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14443. | |
| Zamaporvint | Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RXC004. CAS No. 1900754-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153855. | |
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