Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Monastrol | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| Monastrol | Monastrol is a kinesin Eg5 inhibitor. Induction of apoptosis by monastrol is independent of the spindle checkpoint. Monastrol binds to the KSP-ADP complex, forming a KSP-ADP-monastrol ternary complex, which cannot bind to microtubules productively and cannot undergo further ATP-driven conformational changes. Uses: Antimitotic agents. Synonyms: DL-Monastrol; (S)-Monastrol; (+/-)-Monastrol; 4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic Acid Ethyl Ester. CAS No. 254753-54-3. Molecular formula: C14H16N2O3S. Mole weight: 292.36. |  |
| Monastrol (6-Methyl-4-(3-hydroxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate) | A cell-permeablesmall molecule inhibitor of the mitotic kinesin, Eg5, arrests cells in mitosis with monoastral spindles. Group: Biochemicals. Alternative Names: 6-Methyl-4-(3-hydroxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Dimethylenastron | Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM).The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours. Synonyms: Dimethylenastron. Grades: 98%. CAS No. 863774-58-7. Molecular formula: C16H18N2O2S. Mole weight: 302.39. | |
Our database is helping our users find suppliers everyday.
