Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Monorden A | Monorden A is a metabolite of Humicola sp. FO-2942. It has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. It has anti-Aspergillus niger activity. It inhibits Hsp90 activity by binding to the ATP-binding pocket, thus suppressing cell transformation induced by src, ras and mos. Synonyms: radicicol. Grades: >98%. CAS No. 12772-57-5. Molecular formula: C18H17ClO6. Mole weight: 364.78. |  |
| Monorden C | Monorden C is a metabolite of Humicola sp. FO-2942. It has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. It has anti-Aspergillus niger activity. Synonyms: Pochonin A; 2H-Oxireno[e][2]benzoxacyclotetradecin-6,12(3H,7H)-dione, 8-chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-, (1aR,14S,15aR)-. Grades: >98%. CAS No. 544712-80-3. Molecular formula: C18H19ClO6. Mole weight: 366.79. | |
| Monorden D | Monorden D is a metabolite of Humicola sp. FO-2942. It has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. It has anti-Aspergillus niger activity. Synonyms: Pochonin D. Grades: >98%. CAS No. 544712-82-5. Molecular formula: C18H19ClO5. Mole weight: 350.79. | |
| Monorden E | Monorden E is a metabolite of Humicola sp. FO-2942. It has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. It has anti-Aspergillus niger activity. Molecular formula: C18H21ClO5. Mole weight: 352.81. | |
| Radicicol (Monorden) | Radicicol is a resorcylic acid lactone produced by several fungal species that exhibits broad spectrum antifungal and antitumor activity. Radicicol has been the subject of extensive investigation and been shown to inhibit protein tyrosine kinase, induce the differentiation of HL-60 cells into macrophages, block cell cycle at G1 and G2, suppress NIH 3T3 cell transformation by diverse oncogenes such as src, ras and mos and also suppress the expression of mitogen-inducible cyclooxygenase-2. As a cell differentiation modulator, radicicol has anti-angiogenic activity in vivo, inhibiting the proliferation of plasminogen activator production by vascular endothelial cells. Group: Biochemicals. Alternative Names: Monorden. Grades: Highly Purified. CAS No. 12772-57-5. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Radicicol | Radicicol is an inhibitor of Hsp90 with an IC 50 value < 1 μM, and leads to proteasomal degradation [1]. Radicicol exhibits inhibition on PDK with IC 50 s of 230 μM ( PDK1 ) and 400 μM ( PDK3 ). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB [2]. Radicicol is also an inhibitor of fat mass and obesity-associated protein ( FTO ), with an IC 50 value of 16.04 μM [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Monorden. CAS No. 12772-57-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6769. |  |
| Radicicol | Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Monorden. Product Category: Inhibitors. CAS No. 12772-57-5. Molecular formula: C18H17ClO6. Mole weight: 364.8. Purity: 95%+. IUPACName: (4R,6R,8R,9Z,11E)-16-Chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.06,8]nonadeca-1(15),9,11,16,18-pentaene-2,13-dione. Canonical SMILES: CC1CC2C(O2)C=CC=CC(=O)CC3=C(C(=CC(=C3Cl)O)O)C(=O)O1. Density: 1.364±0.06 g/cm³. Product ID: ACM12772575. Alfa Chemistry ISO 9001:2015 Certified. |  |
Our database is helping our users find suppliers everyday.
