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| Product | Description | |
|---|---|---|
| MTIC | MTIC is a metabolite Temozolomide, which is an alkylating drug. Synonyms: 5-(3-Methyl-1-triazeno)imidazole-4-carboxamide. CAS No. 3413-72-7. Molecular formula: C5H8N6O. Mole weight: 168.16. |  |
| MTIC | MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3413-72-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119696. |  |
| MTIC-d3 (Monomethyl-d3 Triaizeno Imidazole Carboxamide, 3-Methyl-d3-(triazenyl)imidazole-4-carboxamide, 5-(3-Methyl-d3-triazen-1-yl)imidazole-4-carboxamide, NSC 407347-d3) | A labeled metabolite of Temozolomide, an antineoplastic. Group: Biochemicals. Alternative Names: Monomethyl-d3 Triaizeno Imidazole Carboxamide; 3-Methyl-d3-(triazenyl)imidazole-4-carboxamide; 5-(3-Methyl-d3-triazen-1-yl)imidazole-4-carboxamide; NSC 407347-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| MTIC (Monomethyl Triaizeno Imidazole Carboxamide) | A metabolite of Temozolomide, an antineoplastic. Group: Biochemicals. Alternative Names: Monomethyl Triaizeno Imidazole Carboxamide; 3-Methyl (triazenyl)imidazole-4-carboxamide; 5- (3-Methyltriazen-1-yl)imidazole-4-carboxamide, NSC 407347. Grades: Highly Purified. CAS No. 3413-72-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Temozolomide Metabolite - MTIC | One metabolite of Temozolomidee, which is an imidazotetrazine derivative and has been found to be a DNA methylating agent and could be used as an antineoplastic. Grades: > 95%. CAS No. 1232679-46-7. Molecular formula: C5H8N6O. Mole weight: 168.16. | |
| TemozoloMide Metabolite-MTIC | TemozoloMide Metabolite-MTIC. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1232679-46-7. Molecular formula: C5H8N6O. Mole weight: 168.16. Catalog: APB1232679467. |  |
| NU1025 | NU1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. NU1025 enhanced the cytotoxicity of the DNA-methylating agent MTIC, gamma-irradiation and bleomycin 3.5-, 1.4- and 2-fold respectively. Synonyms: NU-1025; NU 1025; 8-Hydroxy-2-methylquinazoline-4-one; NSC 696807. Grades: ≥98%. CAS No. 90417-38-2. Molecular formula: C9H8N2O2. Mole weight: 176.17. | |
| Temozolomide | Imidazotetrazine alkylating agent. An antineoplastic. A cell-permeable, orally bioavailable, blood-brain barrier-permeant MTIC [5-(3-methyltriazen-1-yl-)-imidazole-4-carboxamide] prodrug whose in vivo DNA alkylating activity is employed in anticancer therapy. MGMT (O6-methylguanine DNA methyl transferase) repairs TMZ-damaged DNA lesion by covalently transferring O6-methylation on guanine residues to a cysteine residue on the MGMT, forming the basis of TMZ-resistance in cancer treatment. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, Methazolastone, M&B 39831, Temodal, Temodar; CCRG 81045, TMZ; NSC 362856. Grades: Highly Purified. CAS No. 85622-93-1. Pack Sizes: 10mg, 25mg, 100mg. US Biological Life Sciences. | Worldwide |
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