Mycobacterial Enzyme Suppliers USA
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Product | Description | |
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(3 β ) -24-Bromo-3-[ (tert-butyl) dimethylsilyloxy]-chol-5-ene Quick inquiry Where to buy Suppliers range | (3 β ) -24-Bromo-3-[ (tert-butyl) dimethylsilyloxy]-chol-5-ene is a reactant used in the preparation of series of cholesterol side-chain analogs used in studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P 450 enzymes CYP124A1, CYP125A1 and CYP142A1. Group: Biochemicals. Alternative Names: (3 β ) -24-Bromo-3-[[ (1, 1-dimethylethyl) dimethylsilyl]oxy]-chol-5-ene. Grades: Highly Purified. CAS No. 1384736-07-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
(3 β)-24-Bromochol-5-en-3-ol Quick inquiry Where to buy Suppliers range | (3 β)-24-Bromochol-5-en-3-ol is used as an substrate in the study of ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes. Group: Biochemicals. Grades: Highly Purified. CAS No. 74041-57-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
(3 β)-3-O-tert-Butyldimethylsilyl-cholest-5-ene-3,24-diol Quick inquiry Where to buy Suppliers range | (3 β)-3-O-tert-Butyldimethylsilyl-cholest-5-ene-3,24-diol is a reactant used in the preparation of series of cholesterol side-chain analogs used in studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P 450 enzymes. It is used in the preparation of (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid. Group: Biochemicals. Alternative Names: (3 β ) -3-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-chol-5-en-24-ol. Grades: Highly Purified. CAS No. 84529-86-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
5-Deoxy-2-O-methanesulfonyl-5-tridecyl-D-ribofuranose Quick inquiry Where to buy Suppliers range | 5-Deoxy-2-O-methanesulfonyl-5-tridecyl-D-ribofuranose is a novel and intriguing biomedical compound having applications in research of drug-resistant bacterial infections, including the formidable Mycobacterium tuberculosis. The intricate mechanism of this compound lies in its ability to impede pivotal enzymes crucial to bacterial cell wall bioenhancement, culminating in an irreversible cessation of cellular vitality. Molecular formula: C19H38O6S. Mole weight: 394.57. | |
5-Isopropyl-3-methylphenol Quick inquiry Where to buy Suppliers range | 5-Isopropyl-3-methylphenol is a derivative of Carvacrol (C184600); a major phenolic component of oregano oil and a novel inhibitor of the Mycobacterium tuberculosis (MTB) chorismate mutase (CM) enzyme. Group: Biochemicals. Grades: Highly Purified. CAS No. 3228-3-3. Pack Sizes: 2.5g, 25g. Molecular Formula: C10H14O, Molecular Weight: 150.22. US Biological Life Sciences. | Worldwide |
BTZ043 Quick inquiry Where to buy Suppliers range | The new antitubercular drug candidate 2-[2-S-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one (BTZ043) targets the DprE1 (Rv3790) subunit of the enzyme decaprenylphosphoryl-beta-d-ribose 2'-epimerase. To monitor the potential development of benzothiazinone (BTZ) resistance, a total of 240 sensitive and multidrug-resistant Mycobacterium tuberculosis clinical isolates from four European hospitals were surveyed for the presence of mutations in the dprE1 gene and for BTZ susceptibility. All 240 strains were susceptible, thus establishing the baseline prior to the introduction of BTZ043 in clinical trials. Synonyms: BZT043; BZT 043; BZT-043; 2-[2-S-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one. CAS No. 1161233-85-7. Molecular formula: C17H16F3N3O5S. Mole weight: 431.39. | |
Ciprofloxacin Hydrochloride 10mg/ml Quick inquiry Where to buy Suppliers range | Ciprofloxacin Hydrochloride is a high activity fluoroquinolone antibiotic effective against a broad spectrum of gram positive and negative bacteria such as Pseudomonas, Salmonella, streptococcus and Staphylococcus. Effective against mycoplasma (12 days). Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position. The bactericidal action of ciprofloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA. Ciprofloxacin has been shown to be active against most strains of the following organisms:Gram-Positive Bacteria:Enterococcus faecalis (Many strains are only moderately susceptible); Staphylococcus haemolyticus; Staphylococcus hominis; Staphylococcus saprophyticus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae; Streptococcus pyogenes.Gram-Negative Bacteria:Acinetobacter calcoaceticus subs. anitratus; Acinetobacter calcoaceticus subs. Iwoffi; Aeromonas caviae; Aeromonas hydrophila; Brucella melitensis; Campylobacter coli; Campylobacter jejuni; Citrobacter diversus; Citrobacter freundii; Edwardsiella tarda; Enterobacter aerogenes; Enterobacter cloacae; Escherichia coli; Haemophilus ducreyi; Haemophilus influenzae; Haemophilus parainfluenzae; Klebsiella oxytoca; Klebsiella pneumoniae; Legionella pneumophila; Moraxella (Branhamella) catarrhalis; Morganella morganii; Neisseria gonorrhoeae; Neisseria meningitidis; Pasteurella multocida; Proteus mirabilis; Proteus vulgaris; Providencia rettgeri; Providencia stuartii; Pseudomonas aeruginosa; Salmonella enteritidis; Salmonella typhi; Serratia marcescens; Shigella flexneri; Shigella sonnei; Vibrio cholerae; Vibrio parahaemolyticus; Vibrio vulnificus; Yersinia enterocolitica. Other Organisms:Chlamydia trachomatis (only moderately susceptible); Mycobacterium tuberculosis (only moderately susceptible).Also Available:C5074: Ciprofloxacin Hydrochloride. Group: Biochemicals. Alternative Names: Sterile-filtered aqueous solution. Grades: Molecular Biology Grade. CAS No. 86393-32-0. Pack Sizes: 10ml, 5x10ml. Molecular Formula: C17H18FN3O3 HCl H2O, Molecular Weight: 385.8. US Biological Life Sciences. | Worldwide |
Ciprofloxacin Hydrochloride, Monohydrate Quick inquiry Where to buy Suppliers range | Ciprofloxacin Hydrochloride is a high activity fluoroquinolone antibiotic effective against a broad spectrum of gram positive and negative bacteria such as Pseudomonas, Salmonella, streptococcus and Staphylococcus. Effective against mycoplasma (12 days). Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position. The bactericidal action of ciprofloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA. Ciprofloxacin has been shown to be active against most strains of the following organisms:Gram-Positive Bacteria:Enterococcus faecalis (Many strains are only moderately susceptible); Staphylococcus haemolyticus; Staphylococcus hominis; Staphylococcus saprophyticus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae; Streptococcus pyogenes.Gram-Negative Bacteria:Acinetobacter calcoaceticus subs. anitratus; Acinetobacter calcoaceticus subs. Iwoffi; Aeromonas caviae; Aeromonas hydrophila; Brucella melitensis; Campylobacter coli; Campylobacter jejuni; Citrobacter diversus; Citrobacter freundii; Edwardsiella tarda; Enterobacter aerogenes; Enterobacter cloacae; Escherichia coli; Haemophilus ducreyi; Haemophilus influenzae; Haemophilus parainfluenzae; Klebsiella oxytoca; Klebsiella pneumoniae; Legionella pneumophila; Moraxella (Branhamella) catarrhalis; Morganella morganii; Neisseria gonorrhoeae; Neisseria meningitidis; Pasteurella multocida; Proteus mirabilis; Proteus vulgaris; Providencia rettgeri; Providencia stuartii; Pseudomonas aeruginosa; Salmonella enteritidis; Salmonella typhi; Serratia marcescens; Shigella flexneri; Shigella sonnei; Vibrio cholerae; Vibrio parahaemolyticus; Vibrio vulnificus; Yersinia enterocolitica. Other Organisms:Chlamydia trachomatis (only moderately susceptible); Mycobacterium tuberculosis (only moderately susceptible).Also Available:C5075: Ciprofloxacin Hydrochloride 10mg/ml. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid Hydrochloride; Bay Q3939 Hydrochloride. Grades: Molecular Biology Grade. CAS No. 86393-32-0. Pack Sizes: 1g, 10g, 25g, 50g. Molecular Formula: C17H18FN3O3 HCl H2O, Molecular Weight: 385.8. US Biological Life Sciences. | Worldwide |
Methanol-d Quick inquiry Where to buy Suppliers range | Isotope labelled Methanol (M276585), which is a common chemical reagent in organic synthesis participating in a variety of reactions. Used to prepare novel triazole-polyphenol hybrid compounds as FabG4 (Rv0242c) enzyme inhibitors for the treatment of Mycobacterium Tuberculosis (1). Also used in the synthesis of prodelphinidin B1/B2/B4 which display antitumor activities against prostate cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 1455-13-6. Pack Sizes: 10g, 25 g. Molecular Formula: CH3DO, Molecular Weight: 33.0499999999999. US Biological Life Sciences. | Worldwide |
Methyl Alcohol, 99+% Quick inquiry Where to buy Suppliers range | Methyl Alcohol is a common chemical reagent in organic synthesis participating in a variety of reactions. Used to prepare novel triazole-polyphenol hybrid compounds as FabG4 (Rv0242c) enzyme inhibitors for the treatment of Mycobacterium Tuberculosis (1). Also used in the synthesis of prodelphinidin B1/B2/B4 which display antitumor activities against prostate cancer cells.Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. Group: Biochemicals. Alternative Names: Methanol; Bieleski's Solution; Carbinol; Methanol Cluster; Methyl Hydroxide; Methylol; Monohydroxymethane; NSC 85232; Wood Alcohol; MeOH, Hydroxymethane. Grades: Reagent Grade. CAS No. 67-56-1. Pack Sizes: 1L, 4L, 16L, 64L, 180L. Molecular Formula: CH3OH, Molecular Weight: 32.04. US Biological Life Sciences. | Worldwide |
Nebularine (High Purity) Quick inquiry Where to buy Suppliers range | Nucleoside analog. Cytotoxic. DNA, RNA and protein synthesis inhibitor. Shows anticancer activity. Anti-mycobacterial. Has tuberculostatic activity. Antifungal activity. Antiviral (anti-Herpes). Adenosine deaminase inhibitor. Can be used to analyze structure determinants of DNA that are recognized by DNA repair enzymes, to locate triple helices at G-C sequences or as an universal base, which can bind to all four of the nucleosides of DNA. Group: Biochemicals. Alternative Names: Purine-9-ß-D-ribofuranoside; 9- β-D-Ribofuranosyl-9H-purine; Ribosyl-isopurine; Purinosine; NSC 65423. Grades: Highly Purified. CAS No. 550-33-4. Pack Sizes: 500ug, 1mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
Pyrazinamide Quick inquiry Where to buy Suppliers range | Pyrazinamide is a pyrazine that is used therapeutically as an antitubercular agent. It is a prodrug that stops the growth of Mycobacterium tuberculosis. It is thought to inhibit the enzyme fatty acid synthase (FAS) I, which is required by the bacterium to synthesise fatty acids although this has been discounted. It binds to the ribosomal protein S1 (RpsA) and inhibits trans-translation. Synonyms: Pyrazinecarboxamide; Pyrazinoic acid amide; 2-Pyrazinecarboxamide; Zinamide; Aldinamide; Tebrazid; Pirazinamid; Unipyranamide; Farmizina; Eprazin; Novamid. Grades: >98%. CAS No. 98-96-4. Molecular formula: C5H5N3O. Mole weight: 123.11. |