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| Product | Description | |
|---|---|---|
| myosin ATPase | Proteins of the contractile apparatus of muscle and nonmuscle cells; myosin molecule consists of two heavy chains (about 200 kDa) and two pairs of light chains (15-27 kDa). The head region of the heavy chain contains actin- and ATP-binding sites. ATP hydrolysis provides energy for actomyosin contraction. Group: Enzymes. Enzyme Commission Number: EC 3.6.4.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4699; myosin ATPase; EC 3.6.4.1. Cat No: EXWM-4699. |  |
| 1-[4-(4-Ethoxyphenyl)thiazol-2-yl]-guanidine Hydrobromide | 1-[4-(4-Ethoxyphenyl)thiazol-2-yl]-guanidine Hydrobromide is related to 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide (M226305), which is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is also used in the preparation of thiazole compounds as myosin light chain phosphatase inhibitors for prostate cancer treatment. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg. Molecular Formula: C12H14N4OS; HBr, Molecular Weight: 262.34. US Biological Life Sciences. |  Worldwide |
| 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide | 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is also used in the preparation of thiazole compounds as myosin light chain phosphatase inhibitors for prostate cancer treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 96996-05-3. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N4OS; HBr, Molecular Weight: 248.31. US Biological Life Sciences. | Worldwide |
| 2,3-Butanedione-2-monoxime | 2,3-Butanedione-2-monoxime (BDM) is a non-selective, reversible myosin ATPase inhibitor with phosphatase-like properties. It is non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Uses: Cholinesterase reactivators. Synonyms: BDM; Diacetyl Monoxime; NSC 660; NSC 116103; Biacetyl monooxime. Grade: ≥95%. CAS No. 57-71-6. Molecular formula: C4H7NO2. Mole weight: 101.1. |  |
| 2,3-Butanedione 2-Monoxime | 2,3-Butanedione 2-Monoxime is a reversible inhibitor of myosin ATPase. Group: Biochemicals. Grades: Highly Purified. CAS No. 57-71-6. Pack Sizes: 25g, 50g. Molecular Formula: C4H7NO2, Molecular Weight: 101.1. US Biological Life Sciences. | Worldwide |
| (-)-Blebbistatin | (-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Synonyms: (S)-(-)-Blebbistatin; (S)-blebbistatin; (3aS)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Grade: >98%. CAS No. 856925-71-8. Molecular formula: C18H16N2O2. Mole weight: 292.33. | |
| (-)-Blebbistatin | (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 856925-71-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13441. |  |
| (+)-Blebbistatin | (+)-Blebbistatin is the inactive enantiomer of Blebbistatin, an inhibitor of myosin II ATPase. (+)-Blebbistatin can be used as a negative control of the active enatiomer (-)-Blebbistatin. Synonyms: (R)-(+)-Blebbistatin; (3aR)-(+)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grade: ≥99% by HPLC. CAS No. 1177356-70-5. Molecular formula: C18H16N2O2. Mole weight: 292.34. | |
| (+)-Blebbistatin | (+)-Blebbistatin is the inactive enantiomer of ( - )-Blebbistatin. ( - )-Blebbistatin is a selective inhibitor of myosin II ATPase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177356-70-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107657. | |
| (±)-Blebbistatin | (±)-Blebbistatin is a selective inhibitor of myosin II ATPase. It reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Synonyms: Blebbistatin; (±)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grade: ≥98% by HPLC. CAS No. 674289-55-5. Molecular formula: C18H16N2O2. Mole weight: 292.34. | |
| BTS | A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin's interaction with F-actin. Does not affect platelet myosin II. Synonyms: BTS; BnNHTs; N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine. Grade: >98%. CAS No. 1576-37-0. Molecular formula: C14H15NO2S. Mole weight: 261.34. | |
| BTS | BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC 50 s of ~5 μM for actin- and Ca 2+ -stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine. CAS No. 1576-37-0. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-16690. | |
| CK 1827452 | CK-1827452 is a diaryl urea compound that increases cardiac myosin ATPase activity in a dose-dependent manner that is selective for cardiac myosin over non-cardiac myosins. It promotes myosin cross-bridge formation, increasing the duration and amount of myocyte contraction without affecting intracellular calcium or cAMP. It has been shown to increase cardiac efficiency in clinical studies of patients with chronic heart failure. Group: Biochemicals. Alternative Names: Methyl 4- [ [2-Fluoro-3- [N'- (6-methylpyridin-3-yl) ureido] phenyl] methyl] piperazine-1-carboxylate; 4- [ [2-Fluoro-3- [ [ [ (6-methyl-3-pyridinyl) amino] carbonyl] amino] phenyl] methyl] -1-piperazinecarboxylic Acid Methyl Ester; Omecamtiv Mecarbil. Grades: Highly Purified. CAS No. 873697-71-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??FN?O?, Molecular Weight: 401.43. US Biological Life Sciences. | Worldwide |
| Melittin (honeybee) | Melittin is a polypeptide isolated from the venom of the honey bee (Apis mellifera). It inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane). Synonyms: Honeybee melittin; Bee venom melittin; Forapin; H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2; glycyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonyl-glycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-glutaminamide. Grade: ≥98%. CAS No. 20449-79-0. Molecular formula: C131H229N39O31. Mole weight: 2846.46. | |
| Melittin TFA | Melittin is a polypeptide isolated from the venom of the honey bee (Apis mellifera). It inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane). Synonyms: Melittin trifluoroacetate salt; H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2.TFA; glycyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonyl-glycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-glutaminamide trifluoroacetic acid. Grade: ≥95%. Molecular formula: C133H230F3N39O33. Mole weight: 2960.54. | |
| myosin-heavy-chain kinase | The enzyme from Dictyostelium sp. (slime moulds) brings about phosphorylation of the heavy chains of Dictyostelium myosin, inhibiting the actin-activated ATPase activity of the myosin. One threonine residue in each heavy chain acts as acceptor. While the enzyme from some species is activated by actin, in other cases Ca2+/calmodulin are required for activity. Group: Enzymes. Synonyms: ATP:myosin-heavy-chain O-phosphotransferase; calmodulin-dependent myosin heavy chain kinase; MHCK; MIHC kinase; myosin heavy chain kinase; myosin I heavy-chain kinase; myosin II heavy-chain kinase; [myosin-heavy-chain] kinase; myosin heavy chain kinase A; STK6. Enzyme Commission Number: EC 2.7.11.7. CAS No. 64763-54-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3158; myosin-heavy-chain kinase; EC 2.7.11.7; 64763-54-8; ATP:myosin-heavy-chain O-phosphotransferase; calmodulin-dependent myosin heavy chain kinase; MHCK; MIHC kinase; myosin heavy chain kinase; myosin I heavy-chain kinase; myosin II heavy-chain kinase; [myosin-heavy-chain] kinase; myosin heavy chain kinase A; STK6. Cat No: EXWM-3158. | |
| Native Human Myosin Subfragment-1 | Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of other motility processes in eukaryotes. They are responsible for actin-based motility. The term was originally used to describe a group of similar ATPases found in the cells of both striated muscle tissue and smooth muscle tissue. Applications: Diagnostic controls, calibrators & standards; testing/assay validation; life science; manufacturing. Group: Others. Synonyms: Myosin Subfragment-1; Myosin; Myosin S-1; Myosin 1. Activity: 1 mg/mg solid. Stability: 5 years. Storage: Store at -20°C. Form: Lyophilized from 0.02 mM tris, 0.2 M sodium chloride, pH 8.5. Source: Human Heart. Species: Human. Myosin Subfragment-1; Myosin; Myosin S-1; Myosin 1. Cat No: NATE-0968. | |
| N-Benzyl-p-Toluenesulfonamide (BTS) | A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosins interaction with F-actin. Does not affect platelet myosin II. Group: Biochemicals. Alternative Names: 4-Methyl-N- (phenylmethyl) benzenesulfonamide; Benzyl(4-toluenesulfonyl)amine; N-Benzyl-p-tosylamide; BTS; N-Tosylbenzylamine; NSC 37123. Grades: Highly Purified. CAS No. 1576-37-0. Pack Sizes: 25mg, 100mg. US Biological Life Sciences. | Worldwide |
| (S)-3'-amino Blebbistatin | (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. Synonyms: (-)-3'-amino Blebbistatin; m-amino Blebbistatin; meta-amino Blebbistatin; (3aS)-1-(3-aminophenyl)-1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grade: ≥95%. CAS No. 2097141-18-7. Molecular formula: C18H17N3O2. Mole weight: 307.35. | |
| (S)-3'-hydroxy Blebbistatin | (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. Synonyms: (-)-3'-hydroxy Blebbistatin; meta-hydroxy-Blebbistatin; m-hydroxy-Blebbistatin; 1,2,3,3aS-tetrahydro-3a-hydroxy-1-(3-hydroxyphenyl)-6-methyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grade: ≥95%. CAS No. 2097136-42-8. Molecular formula: C18H16N2O3. Mole weight: 308.33. | |
| (S)-4'-nitro-Blebbistatin | (S)-4'-nitro-Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. Synonyms: (-)-4'-nitro-Blebbistatin; p-nitro-Blebbistatin; para-nitro-Blebbistatin; (3aS)-1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-(4-nitrophenyl)-4H-pyrrolo[2,3-b]quinolin-4-one. Grade: ≥95%. CAS No. 1621326-32-6. Molecular formula: C18H15N3O4. Mole weight: 337.33. | |
| (S)-nitro-Blebbistatin | (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. Synonyms: S-(-)-7-Desmethyl-8-nitro Blebbistatin; (3aS)-3a-hydroxy-7-nitro-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one. Grade: ≥98%. CAS No. 856925-75-2. Molecular formula: C17H13N3O4. Mole weight: 323.3. | |
| Soybean oil | Soybean oil. Synonyms: Best One Soya;Bionatrol;CAP 18;CAP 18 (oil);CT 7000;Destiny HC;Fats and Glyceridic oils, soybean;HY 3050. CAS No. 8001-22-7. Pack Sizes: 250 mL in poly bottle. Product ID: CDC10-0079. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Soybean oil; CDC10-0079; 8001-22-7; Best One Soya; Bionatrol; CAP 18; CAP 18 (oil); CT 7000; Destiny HC; Fats and Glyceridic oils, soybean; HY 3050; 232-274-4; MFCD00132356; 8001-22-7. Purity: 0.99. Color: Colorless to Yellow. EC Number: 232-274-4. Physical State: Oil. Quality Level: 200. Storage: 2-8°C. Application: It may be used as a crude source for triglycerides and other lipids. Soybean oil is a potential raw material in oxygenated fatty acid production. It may be used in the synthesis of epoxidized-soybean oil (ESO). Density: 0.917 g/mL at 25 °C(lit.). Product Description: Soybean oil (SBO) is a vegetable oil widely used as biodegradable lubricant. It increases left ventricular contractility associated myosin ATPase and sarcoplasmic reticulum calcium pump (SERCA2a) in isolated hearts from rats. SBO is shown to reduce both total and non-HDL serum cholesterol and triglycerides induced by atherogenic diet in rats. It may be transesterified to biodiesel using CaO as a solid base catalyst. It may also be transesterified to biodiesel using methanol and ethanol. |  |
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