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dA(Bz)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for specialized oligonucleotide synthesis. The adenine base is protected with a benzoyl (Bz) group at the N6 position to prevent side reactions during synthesis. At the 3' position, the methoxy group replaces the standard hydroxyl group, providing unique structural properties and increased chemical stability to the oligonucleotide. The phosphoramidite functionality ensures efficient incorporation into oligonucleotide chains via automated synthesis. This modification is particularly useful in applications requiring oligonucleotides with altered backbone properties, improved hybridization characteristics, or enhanced resistance to enzymatic degradation, such as in therapeutic nucleic acids and molecular biology studies. Synonyms: dA(Bz)-3'-Methoxy Phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[methyl bis(1-methylethyl)phosphoramidite]; N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Me phosphonamidite; (2R,3S,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite; 2'-Deoxy Adenosine (n-Bz) methyl phosphoramidite; DNA A(Bz) OMe-amidite; dA(Bz) OMe-amidite. Grade: ≥98%. CAS No. 84416-82-0. Molecular formula: C45H51N6O7P. Mole weight: 818.90.
5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite, an indispensable biomolecular tool, profoundly impacts the dynamic biomedical sphere. Its paramount significance lies in its pivotal role as a reagent for nucleoside or oligonucleotide synthesis, revolutionizing the study of DNA-protein interactions, gene expression, and research in molecular biology. Synonyms: N6-Benzoyl-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite; dA(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-adenosine 3'-[2-cyanoethyl N,?N-Bis(1-methylethyl)?phosphoramidite]; DMT-dA(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥98% by HPLC. CAS No. 98796-53-3. Molecular formula: C47H52N7O7P. Mole weight: 857.93.
5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine
5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine boasts a promising pharmacological arsenal to combat a range of viral infections. With virucidal efficacy that targets the DNA replication machinery of several virus strains, the drug holds considerable therapeutic potential for cases of hepatitis B and C, as well as herpes and shingles. Furthermore, its anti-neoplastic properties make it a noteworthy exploratory tool for certain types of cancer treatment. Synonyms: 5'-O-(4,4'-dimethoxytrityl)-N4-benzoyl-2'-fluoro-2'-deoxycytidine; N4-Bz-DMT-2'-F-dC; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine; N4-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxycytidine; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine; 5'-O-DMTr-2'-F-dC(Bz); 5'-DMT-2'-F-Bz-dC; 5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-fluoro-2'-deoxyadenosine; N-{1-{5-O-[bis-(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-D-arabinofuranosyl}-1,2-dihydro-2-oxo-4-pyrimidinyl}-benzamide; N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-deoxy-2'-fluoro-Cytidine; 5'-O-DMT-N4-Bz-2'-F-dC. Grade: ≥98% by HPLC. CAS No. 146954-77-0. Molecular formula: C37H34FN3O7. Mole weight: 651.68.
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is useful in various DNA and RNA projects ranging from modification to site-selective activation, and many other projects. Synonyms: N6-Benzoyl-2'-deoxy-5'-O-DMTr-adenosine; 5'-O-DMT-N6-benzoyl-2'-deoxy-D-adenosine; N6-Benzoyl-5'-O-DMT-2'-deoxy-D-adenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxyadenosine; 5'-O-(Dimethoxytrityl)-N-benzoyldeoxyadenosine; 5'-O-(Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine; N6-Benzoyl-5'-O-(dimethoxytrityl)deoxyadenosine. Grade: ≥95%. CAS No. 64325-78-6. Molecular formula: C38H35N5O6. Mole weight: 657.71.
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