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N6-Methyladenosine. Group: Biochemicals. Alternative Names: (-)-6-(Methylamino)purine riboside. Grades: Highly Purified. CAS No. 60209-41-8,1867-73-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C11H15N5O4. US Biological Life Sciences.
Worldwide
N6-Methyladenosine
N6-Methyladenosine is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast. Synonyms: 6-Methyladenosine; N(6)-Methyladenosine; N-Methyladenosine; 6-Methylaminopurinosine; 6-Methylaminopurine D-riboside; 6-Methylaminopurine ribonucleoside; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol; 6-Methylamino-9-beta-D-ribofuranosyl-purine; NSC 29409. Grades: >98%. CAS No. 1867-73-8. Molecular formula: C11H15N5O4. Mole weight: 281.27.
N6-Methyladenosine
N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Methyladenosine; N-Methyladenosine. CAS No. 1867-73-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0086.
N6-Methyladenosine 5'-monophosphate sodium salt
N6-Methyladenosine 5'-monophosphate sodium salt is an activator of glycogen phosphorylase b. Applications: An activator of glycogen phosphorylase b. Group: Coenzymes. Synonyms: 9H-Purin-6-amine, N-methyl-9-(5-O-phosphonopentofuranosyl)-, sodium salt. CAS No. 81921-35-9. Purity: ≥98%. Mole weight: 383.23. Appearance: Crystalline or crystalline needles. Form: Solid. 9H-Purin-6-amine, N-methyl-9-(5-O-phosphonopentofuranosyl)-, sodium salt; N6-Methyladenosine 5'-monophosphate sodium salt; 81921-35-9. Cat No: COEC-113.
N6-Methyladenosine-5'-monophosphate Sodium Salt
N6-Methyladenosine-5'-monophosphate Sodium Salt. Group: Biochemicals. Grades: Reagent Grade. CAS No. 81921-35-9. Pack Sizes: 5mg, 25mg, 100mg. Molecular Formula: C11H14N5O7PNa2, Molecular Weight: 405.21. US Biological Life Sciences.
Worldwide
N6-Methyladenosine-5'-triphosphate lithium salt
N6-Methyladenosine-5'-triphosphate lithium salt is an exceptionally robust stimulant of methyltransferases, standing as a pivotal constituent employed for the scrutiny of RNA modifications. Synonyms: 6-Me-ATP. Grades: ≥ 95%. Molecular formula: C11H18N5O13P3·xLi. Mole weight: 521.21 (free acid).
N6-Methyladenosine-5'-triphosphate sodium salt
N6-Methyladenosine-5'-triphosphate sodium salt is an essential nucleotide analog, finding utmost utility in the intricate investigations concerning the captivating realm of RNA modifications and RNA processing. Synonyms: 6-Me-ATP Na. Grades: ≥ 95%. Molecular formula: C11H18N5O13P3·xNa. Mole weight: 521.21 (free acid).
N6-Methyladenosine N1-oxide
It is an antiviral agent. Synonyms: (2R,3S,4R,5R)-2-Hydroxymethyl-5-(6-methylamino-1-oxy-purin-9-yl)-tetrahydro-furan-3,4-diol. Grades: ≥95%. CAS No. 113509-54-9. Molecular formula: C11H15N5O5. Mole weight: 297.27.
2'-Deoxy-N6-methyladenosine 5'-triphosphate sodium salt
2'-Deoxy-N6-methyladenosine 5'-triphosphate sodium salt, a frequently used nucleotide analog in the study of RNA modifications, has the capability to replace natural adenosine and therefore induce changes to the RNA structure, stability and function. Such modifications brought upon by N6-methyladenosine(m6A) are of great academic and scientific interest. What's more, imaging techniques can be employed to visualize RNA through the deployment of this compound. Nonetheless, it remains inappropriate for treating diseases as it is not clinically approved. Synonyms: DM6ATP. Molecular formula: C11H15N5Na3O12P3. Mole weight: 571.15.
5'(R)-C-Methyl-N6-methyladenosine
5'(R)-C-Methyl-N6-methyladenosine is a profound biomedical compound widely employed in research investigations, serving as an exquisite analog of the indigenous RNA alteration known as N6-methyladenosine (m6A). Notably, this intriguing modification materializes as a pivotal player within epitranscriptomics. Remarkably, this chemically enhanced nucleoside pioneers the unveiling of profound insights into the intricate interplay between RNA methylation, gene expression, transcript stability is and RNA-protein interactions. Grades: ≥95%. Molecular formula: C12H17N5O4. Mole weight: 295.29.
3'-Deoxy-3'-a-C-methyl-N6-dimethyladenosine
3'-Deoxy-3'-a-C-methyl-N6-dimethyladenosine is a highly potent and selectively targeted inhibitor, finding its indispensable utility within the expansive biomedical realm for the probing and unraveling of intricate RNA molecule modifications. When employed with precision, this compound demonstrates exceptional efficacy in delving into the multifaceted intricacies of N6-methyladenosine (m6A) methylation, thereby unraveling the elusive machinations governing cellular processes, gene expression, and the underlying mechanisms of afflictions spanning from cancer to neurological disorders. Synonyms: 3'-Deoxy-3'-a-C-methyl-N6,N6-dimethyladenosine; 3'-Deoxy-3'-α-C-methyl-N6-dimethyladenosine. Grades: ≥95%. CAS No. 2095417-44-8. Molecular formula: C13H19N5O3. Mole weight: 293.32.
5'-DMT-2'-TBDMS-N6-Me-rA
5'-DMT-2'-TBDMS-N6-Me-rA is an extraordinary modified RNA nucleoside, allowing for unrivaled applications in the intricate domain of drug research and development, explicitly targeting RNA-based ailments encompassing malignant neoplasms, viral afflictions is as well as hereditary anomalies. Synonyms: 2'-O-(tert-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-N6-methyladenosine; N6-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-t-butyldimethylsilyladenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-methyl-Adenosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-methyladenosine. Grades: ≥98% by HPLC. CAS No. 588698-75-3. Molecular formula: C38H47N5O6Si. Mole weight: 697.91.
5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-methyl-adenosine 3'-CE phosphoramidite is a vital compound used in the biomedical industry for synthesizing RNA molecules. This phosphoramidite aids in the incorporation of modified adenosine bases during RNA synthesis, enabling researchers to study specific drug targets or diseases related to N6-methyladenosine methylation. By providing precise adenosine modifications, this product facilitates the investigation of gene expression and regulatory mechanisms, leading to potential breakthroughs in drug discovery and disease understanding. Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N6-Me-rA phosphoramidite; 5'-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2'-O-[dimethyl (2-methyl-2-propanyl)silyl]-N-methyladenosine. Grades: ≥98% by HPLC. CAS No. 588698-79-7. Molecular formula: C47H64N7O7PSi. Mole weight: 898.11.
FB23 inhibitor
FB23 is a potent and selective inhibitor of N6-methyladenosine (m6A) demethylase FTO (fat mass and obesity associated protein). It moderately inhibits proliferation of NB4 and MONOMAC6 cells. FB23 demonstrates its potent inhibitory impact in AML models. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FB23 inhibitor; FB-23; FB 23. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2243736-35-6. Molecular formula: C18H14Cl2N2O3. Mole weight: 377.22. Purity: >98%. IUPACName: 2-[[2,6-Dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]benzoic acid. Canonical SMILES: O=C(O)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)ON=C3C)C=C2Cl. Product ID: ACM2243736356. Alfa Chemistry ISO 9001:2015 Certified.
N6-Benzoyl-5'-O-DMT-N3-methyladenosine
N6-Benzoyl-5'-O-DMT-N3-methyladenosine, an indispensable compound widely employed in biomedical research, assumes a pivotal role in unveiling the intricate layers of RNA modifications and the enigmatic realm of epigenetics. Boasting an unparalleled structural configuration, this prodigious entity proffers unparalleled insights into the multifarious machinations underpinning N6-methyladenosine (m6A)'s profound impact on gene expression and RNA metabolism. Synonyms: N6-Benzoyl-5'-O-DMT-N3-methyl-D-adenosine. Molecular formula: C39H39N5O7. Mole weight: 689.77.
N6-Formyl-adenosine
N6-Formyl-adenosine is an intermediate with modified ribonucleoside formed by chemical oxidation of N6-methyladenosine mediated by bicarbonate-activated hydrogen peroxide. Synonyms: N-Formyl-adenosine; N-(9-β-D-Ribofuranosyl-9H-purin-6-yl)formamide. Grades: 97%. CAS No. 6706-56-5. Molecular formula: C11H13N5O5. Mole weight: 295.25.
N6-Methyl-ATP
N6-Methyl-ATP, a base modified analog of adenosine, is able to substitute for ATP in some biological systems. Besides, N6-Methyl-ATP is a potent agonist for P2Y-purinoceptors in the guinea pig, taenia coli. Synonyms: N6-Methyladenosine-5'-Triphosphate; m6ATP. Grades: ≥ 95 % by HPLC. CAS No. 3130-39-0. Molecular formula: C11H18N5O13P3. Mole weight: 521.21.
N-[(Dimethylamino)methylene]-2',3',5'-tris-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosine is an intermediate in the synthesis of N6-Formyl-adenosine. N6-Formyl-adenosine is an intermediate with modified ribonucleoside formed by chemical oxidation of N6-methyladenosine mediated by bicarbonate-activated hydrogen peroxide. Synonyms: (Z) -N'- (9- ( (2R, 3R, 4R, 5R) -3, 4-Bis ( (tert-butyldimethylsilyl) oxy) -5- ( ( (tert-butyldimethylsilyl) oxy) methyl) tetrahydrofuran-2-yl) -9H-purin-6-yl) -N, N-dimethylformimidamide. CAS No. 1612841-25-4. Molecular formula: C31H60N6O4Si3. Mole weight: 665.1.
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