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Nebivololhydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 152520-56-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Nebivololhydrochloride
Nebivolol (R 065824) hydrochloride is an orally active beta receptor blocker and has the high beta(1)-receptor affinity.Nebivololhydrochloride has direct vasodilator properties and adrenergic blocking characteristics. Nebivololhydrochloride can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 065824 hydrochloride. CAS No. 152520-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0203A.
A competitive, highly selective beta-1-adrenoceptor antagonist (more than 40-fold selective for beta-1 than beta-2; Ki1 and beta-2, respectively). The most beta-1-selective chemical of the beta-blockers tested so far. Used for treatment of essential hypertension and highly cardioselective. Induces mild vasodialation via a nitric oxide- and cGMP-depedent pathways (EC50 = 11.36uM in renal arteries). Group: Biochemicals. Grades: Highly Purified. CAS No. 152520-56-4. Pack Sizes: 10mg. US Biological Life Sciences.
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4-Hydroxy Nebivolol, Hydrochloride Hydrate (Mixture of Diastereomers)
A metabolite of Nebivolol. Group: Biochemicals. Alternative Names: 6-Fluoro-α - [ [ [2- (6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-yl) -2-hydroxyethyl] amino] methyl] -3, 4-dihydro-4-hydroxy-2H-1-benzopyran-2-methanol Hydrochloride Hydrate. Grades: Highly Purified. CAS No. 178383-76-1. Pack Sizes: 500ug. US Biological Life Sciences.
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(-)-Nebivolol-d4 Hydrochloride
Labeled (-)-Nebivolol. A β1-Adrenergic blocker. Used as an antihypertensive. Group: Biochemicals. Alternative Names: (α S, α S, 2R, 2S)-α , α -[Iminobis (methylene)]bis[6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-methanol]-d4 Hydrochloride; [2S-[2R*[R*[R* (S*)]]]]-α , α '-[Iminobis (methylene)]bis[6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-methanol-d4 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(+)-Nebivolol-d4 Hydrochloride
Labeled (+)-Nebivolol. A β1-Adrenergic blocker. Used as an antihypertensive. Group: Biochemicals. Alternative Names: (α R, α R, 2R, 2S)-α , α -[Iminobis (methylene)]bis[6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-methanol]-d4; [2R-[2R*[R*[R* (S*)]]]]-α , α '-[Iminobis (methylene)]bis[6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-methanol-d4 Hydrochloride; (S,R,R,R)-Nebivolol-d4 Hydrochloride; Dexnebivolol-d4 Hydrochloride; R 67138-d4; d-Nebivolol-d4 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Nebivolol Impurity 27 (Hydrochloride)
Nebivolol Impurity 27 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-(benzylazanediyl)bis(1-(6-fluorochroman-2-yl)ethanol) hydrochloride. CAS No. 1803397-45-6. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB1803397456.
Nebivolol Impurity 49 (Hydrochloride)
Nebivolol Impurity 49 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(benzyl((S)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01460.
Nebivolol Impurity 50 (Hydrochloride)
Nebivolol Impurity 50 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(benzyl((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01459.
Nebivolol Impurity 51 (Hydrochloride)
Nebivolol Impurity 51 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(benzyl((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((R)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01458.
Nebivolol Impurity 52 (Hydrochloride)
Nebivolol Impurity 52 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-(benzyl((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01457.
Nebivolol Impurity 72 (Hydrochloride)
Nebivolol Impurity 72 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-(benzyl((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)-1-((S)-6-fluorochroman-2-yl)ethanol hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01444.
Nebivolol Impurity 81 (Hydrochloride)
Nebivolol Impurity 81 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S,1R,1'R)-2,2'-(benzylazanediyl)bis(1-((S)-6-fluorochroman-2-yl)ethanol) hydrochloride. Molecular Formula: C29H31F2NO4·HCl. Mole Weight: 532.02. Catalog: APB01440.
rac nebivololhydrochloride
rac nebivololhydrochloride. Group: Biochemicals. Alternative Names: a, a'-[Iminobis (methylene)]bis[6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-methanol]; a, a'- (Iminodimethylene) bis[6-fluoro-2-chromanmethanol] hydrochloride; Lobivon. Grades: Highly Purified. CAS No. 169293-50-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C22H26ClF2NO4. US Biological Life Sciences.
A b1-Adrenergic blocker. Used as an antihypertensive. Group: Biochemicals. Alternative Names: (aR, aR, 2R, 2S)-rel-a, a-[Iminobis (methylene)]bis[6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-methanol]; a, a- (Iminodimethylene) bis[6-fluoro-2-chromanmethanol] Hydrochloride; Lobivon; Nebilet;Nebilox; R-67555. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
4-Hydroxy Nebivolol
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.11 nM. Synonyms: 4-Hydroxy nebivololhydrochloride; 6-fluoro-2-[2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]-1-hydroxyethyl]-3,4-dihydro-2H-chromen-4-ol;hydrate;hydrochloride. Grades: > 95%. CAS No. 178383-76-1. Molecular formula: C22H25F2NO5. Mole weight: 421.45.
Nebivolol HCl
Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM. Uses: Adrenergic beta-1 receptor agonists. Synonyms: Nebivolol HCl; NebivololHydrochloride; Silostar; Bystolic, R-67145; R 67145; R67145. Grades: >98%. CAS No. 152520-56-4. Molecular formula: C22H25F2NO4.HCl. Mole weight: 441.9.
Nebivolol Impurity 10 HCl (RS,SR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.31 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'S,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-23-6. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 11 (SR,SR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.32 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'R,?2S,?2'R)?-. Grades: > 95%. Molecular formula: C22H25F2NO4. Mole weight: 405.45.
Nebivolol Impurity 12 HCl (RR,RR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.33 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-25-8. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 13 HCl (SS,SS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.34 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'S,?2S,?2'S)?-. Grades: > 95%. CAS No. 920275-27-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 14 (D-Nebivolol) (SR,RR) HCl
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.35 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2R,?2'S)?-. Grades: > 95%. CAS No. 213132-06-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity 2 HCl (SR,RS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.20 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2S,?2'S)?-. Grades: > 95%. CAS No. 920275-19-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity I HCl (RR,SR)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.21 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'S,?2R,?2'R)?-. Grades: > 95%. CAS No. 920275-20-3. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Impurity II HCl (SS,RS)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.22 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'S,?2S,?2'S)?-. Grades: > 95%. CAS No. 920299-27-0. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Related Compound 1 HCl (Mixture of (RR,SR) and (SS,RS) Isomer)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.36 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'R,?2S,?2'R)?-; + 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'S,?2R,?2'S)?-. Grades: > 95%. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
Nebivolol Related Compound 3 HCl (Mixture of (RS,SR), (SR,SR) and (SR,RS) Isomers)
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.38 nM. Synonyms: 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αR,?α'S,?2S,?2'R)?-; + 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'R,?2S,?2'R)?-; 2H-1-Benzopyran-2-methanol, α,?α'-[iminobis(methylene)?]?bis[6-fluoro-3,?4-dihydro-, hydrochloride (1:1)?, (αS,?α'R,?2S,?2'R)?-. Grades: > 95%. Molecular formula: C22H25F2NO4. HCl. Mole weight: 441.91.
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