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Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG1341. CAS No. 159989-64-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15287.
Nelfinavir-d3
An antiviral. Labeled HIV protease inhibitor. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e ; AG 1341. Grades: Highly Purified. CAS No. 1217629-70-3. Pack Sizes: 1mg. Molecular Formula: C??H??D?N?O?S, Molecular Weight: 570.8. US Biological Life Sciences.
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Nelfinavir-[d3]
Nelfinavir-[d3] is the labelled analogue of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor. Synonyms: Nelfinavir D3; Viracept-d3; (3S-(2(2S*,3S*),3alpha,4abeta,8abeta))-N-(1,1-Dimethylethyl)decahydro-2-(2-hydroxy-3-((3-hydroxy-2-methylbenzoyl)amino)-4-(phenylthio)butyl)-3-isoquinolinecarboxamide-d3. Grade: ≥96%; ≥98% atom D. CAS No. 1217629-70-3. Molecular formula: C32H42D3N3O4S. Mole weight: 570.80.
Nelfinavir Hydroxy-tert-butylamide
A metabolite of Nelfinavir, which is used as an antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 213135-56-9. Pack Sizes: 1mg. Molecular Formula: C32H45N3O5S, Molecular Weight: 583.78. US Biological Life Sciences.
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Nelfinavir Mesylate
Nelfinavir Mesylate (AG 1343 Mesylate) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) for HIV infection. Nelfinavir Mesylate (AG 1343 Mesylate) is a broad-spectrum, anticancer agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG 1343 Mesylate. CAS No. 159989-65-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15287A.
Nelfinavir, Mesylate ( (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e , AG-1343)
An antiviral. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e ; AG-1343. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Nelfinavir Mesylate (AG-1343, AG1343, Viracept)
Nelfinavir is a potent competitive inhibitor of the HIV-1 protease. It is reported that it can also inhibit the growth of various cell types and trigger apoptosis. Besides being a protease inhibitor used in the therapeutic agent for acquired immunodeficiency syndrome (AIDS), it is also stimulates autophagy and and exhibits anti-cancer properties. It appears to do by inhibition of the Akt/PKB signaling pathway and activation of endoplasmic reticulum stress with subsequent unfolded protein response (1). Nelfinavir has also been shown to treat SARS-coronavirus (2), and is being tested currently to treat COVID-19. Group: Biochemicals. Alternative Names: AG-1343, AG1343, Viracept; (3S, 4aS, 8aS)-N-tert-butyl-2-[(2R, 3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3, 4, 4a, 5, 6, 7, 8, 8a-octahydro-1H-isoquinoline-3-carboxamide; methanesulfonic acid. Grades: Highly Purified. CAS No. 159989-65-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?S? , Molecular Weight: 663.89. US Biological Life Sciences.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Nelfinavir Sulfone
Nelfinavir Sulfone is an impurity of Nelfinavir Mesylate. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl sulfonyl ) bu tyl ]-3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 1041389-29-0. Pack Sizes: 10mg. US Biological Life Sciences.
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Nelfinavir Sulfoxide
Nelfinavir Sulfoxide is an impurity of Nelfinavir Mesylate. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl sulfinyl ) bu tyl ]-3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 1041389-28-9. Pack Sizes: 10mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Atazanavir
Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir ; Reyataz ; Atazanavir sulfate ; CGP75136 ; CGP75176 ; CGP75355 ; BMS232632 ; CGP 73547 ; CGP 75136 ; CGP 75176 ; CGP 75355 ; CGP-73547 ; CGP-75136 ; CGP-75176 ; CGP-75355 ; BMS 232632 ; BMS-232632 ; BMS-232632-05 ; C413408. Grade: 0.98. CAS No. 198904-31-3. Molecular formula: C38H52N6O7. Mole weight: 704.869.
Atazanavir-[d6]
Atazanavir-[d6] is the labelled analogue of Atazanavir. Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir D6; (3S,8S,9S,12S)-12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-Pentaazatetradecanedioic Acid 14-di(methyl-d3) Ester. Grade: ≥98%; ≥99% atom D. CAS No. 1092540-50-5. Molecular formula: C38H46D6N6O7. Mole weight: 710.89.
Benzyl ((2R,3R)-3-Hydroxy-1-(phenylthio)heptan-2-yl)carbamate is a derivative of N-Carbobenzyloxy-3-phenylthio-L-alanine (C176530) which is an intermediate in the synthesis of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C21H27NO3S, Molecular Weight: 373.51. US Biological Life Sciences.
Benzyl ((2R,3S)-3-Hydroxy-1-(phenylthio)-4-(trimethylsilyl)butan-2-yl)carbamate is a derivative of N-Carbobenzyloxy-3-phenylthio-L-alanine (C176530) which is an intermediate in the synthesis of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C21H29NO3SSi, Molecular Weight: 403.61. US Biological Life Sciences.
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