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An HIV-1 protease inhibitor. It inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles. Uses: Hiv protease inhibitors. Synonyms: Viracept; AG 1341; AG-1341; AG1341. Grades: ≥98%. CAS No. 159989-64-7. Molecular formula: C32H45N3O4S. Mole weight: 567.78.
Nelfinavir
Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG1341. CAS No. 159989-64-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15287.
Nelfinavir-d3
An antiviral. Labeled HIV protease inhibitor. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e ; AG 1341. Grades: Highly Purified. CAS No. 1217629-70-3. Pack Sizes: 1mg. Molecular Formula: C??H??D?N?O?S, Molecular Weight: 570.8. US Biological Life Sciences.
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Nelfinavir Hydroxy-tert-butylamide
A metabolite of Nelfinavir, which is used as an antiviral. Group: Biochemicals. Grades: Highly Purified. CAS No. 213135-56-9. Pack Sizes: 1mg. Molecular Formula: C32H45N3O5S, Molecular Weight: 583.78. US Biological Life Sciences.
Worldwide
Nelfinavir Hydroxy-tert-butylamide
An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-6 protease inhibitor. Synonyms: Nelfinavir Hydroxy-tert-butylamide; (3S,4aS,8aS)-Decahydro-N-(2-hydroxy-1,1-dimethylethyl)-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide. Grades: > 95%. CAS No. 213135-56-9. Molecular formula: C32H45N3O5S. Mole weight: 583.8.
Nelfinavir Mesylate
Nelfinaviris a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor. Synonyms: AG-1341; AG 1341; AG1341. Grades: >98%. CAS No. 159989-65-8. Molecular formula: C33H49N3O7S2. Mole weight: 663.89.
Nelfinavir Mesylate
Nelfinavir Mesylate (AG 1343 Mesylate) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) for HIV infection. Nelfinavir Mesylate (AG 1343 Mesylate) is a broad-spectrum, anticancer agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG 1343 Mesylate. CAS No. 159989-65-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15287A.
Nelfinavir, Mesylate ( (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e , AG-1343)
An antiviral. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl thio) butyl ]-3-isoquinolinecarboxamid e ; AG-1343. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Nelfinavir Mesylate (AG-1343, AG1343, Viracept)
Nelfinavir is a potent competitive inhibitor of the HIV-1 protease. It is reported that it can also inhibit the growth of various cell types and trigger apoptosis. Besides being a protease inhibitor used in the therapeutic agent for acquired immunodeficiency syndrome (AIDS), it is also stimulates autophagy and and exhibits anti-cancer properties. It appears to do by inhibition of the Akt/PKB signaling pathway and activation of endoplasmic reticulum stress with subsequent unfolded protein response (1). Nelfinavir has also been shown to treat SARS-coronavirus (2), and is being tested currently to treat COVID-19. Group: Biochemicals. Alternative Names: AG-1343, AG1343, Viracept; (3S, 4aS, 8aS)-N-tert-butyl-2-[(2R, 3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3, 4, 4a, 5, 6, 7, 8, 8a-octahydro-1H-isoquinoline-3-carboxamide; methanesulfonic acid. Grades: Highly Purified. CAS No. 159989-65-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?S? , Molecular Weight: 663.89. US Biological Life Sciences.
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Nelfinavir Oxazole Impurity (Impurity A)
An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor. Synonyms: 3-Isoquinolinecarboxam?ide, 2-[(2R)?-2-[(4S)?-4,?5-dihydro-2-(3-hydroxy-2-methylphenyl)?-4-oxazolyl]?-2-hydroxyethyl]?-N-(1,?1-dimethylethyl)?decahydro-, (3S,?4aS,?8aS)?-. Grades: > 95%. CAS No. 188936-07-4. Molecular formula: C26H39N3O4. Mole weight: 457.62.
Nelfinavir Regeoisomer (Impurity D)
An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-4 protease inhibitor. Synonyms: [3S- (3S, 4aS, 8aS, 2'R, 3'R) ]-2-[3'-N-CBz-amino-2'-hydroxy-4'- (phenyl) thio]butyldecahydroisoquinoline-3-N-t-butylcarboxamide; [ (1R, 2R) -3-[ (3S, 4aS, 8aS) -3-[[ (1, 1-Dimethylethyl) amino]carbonyl]octahydro-2 (1H) -isoquinolinyl]-2-hydroxy-1-[ (phenylthio) methyl]propyl]carbamic Acid Phenylmethyl Ester. Grades: > 95%. CAS No. 159878-04-3. Molecular formula: C32H45N3O4S. Mole weight: 567.8.
Nelfinavir Sulfone
Nelfinavir Sulfone is an impurity of Nelfinavir Mesylate. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl sulfonyl ) bu tyl ]-3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 1041389-29-0. Pack Sizes: 10mg. US Biological Life Sciences.
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Nelfinavir Sulfone Impurity (Impurity C)
An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-3 protease inhibitor. Synonyms: Nelfinavir Sulfone; (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfonyl)butyl]-3-isoquinolinecarboxamide. Grades: > 95%. CAS No. 1041389-29-0. Molecular formula: C32H45N3O6S. Mole weight: 599.8.
Nelfinavir Sulfoxide
Nelfinavir Sulfoxide is an impurity of Nelfinavir Mesylate. Group: Biochemicals. Alternative Names: (3S, 4aS, 8aS) -N- (1, 1-Di methyl ethyl ) dec a hydro-2- [ (2R, 3R) -2- hydroxy-3- [ (3- hydroxy-2-methyl benzoyl ) ami no]-4-(phenyl sulfinyl ) bu tyl ]-3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 1041389-28-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Nelfinavir Sulfoxide Impurity (Impurity B)
An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-2 protease inhibitor. Synonyms: Nelfinavir Sulfoxide; (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylsulfinyl)butyl]-3-isoquinolinecarboxamide; USP Nelfinavir Related Compound A. Grades: > 95%. CAS No. 1041389-28-9. Molecular formula: C32H45N3O5S. Mole weight: 583.8.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
An intermediate in the synthesis for the metabolite of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Atazanavir
Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir ; Reyataz ; Atazanavir sulfate ; CGP75136 ; CGP75176 ; CGP75355 ; BMS232632 ; CGP 73547 ; CGP 75136 ; CGP 75176 ; CGP 75355 ; CGP-73547 ; CGP-75136 ; CGP-75176 ; CGP-75355 ; BMS 232632 ; BMS-232632 ; BMS-232632-05 ; C413408. Grades: 0.98. CAS No. 198904-31-3. Molecular formula: C38H52N6O7. Mole weight: 704.869.
Benzyl ((2R,3R)-3-Hydroxy-1-(phenylthio)heptan-2-yl)carbamate is a derivative of N-Carbobenzyloxy-3-phenylthio-L-alanine (C176530) which is an intermediate in the synthesis of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C21H27NO3S, Molecular Weight: 373.51. US Biological Life Sciences.
Benzyl ((2R,3S)-3-Hydroxy-1-(phenylthio)-4-(trimethylsilyl)butan-2-yl)carbamate is a derivative of N-Carbobenzyloxy-3-phenylthio-L-alanine (C176530) which is an intermediate in the synthesis of Nelfinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C21H29NO3SSi, Molecular Weight: 403.61. US Biological Life Sciences.
Worldwide
Phenyl disulfide
An impurity of Nelfinavir, which is a potent and orally bioavailable human immunodeficiency virus HIV-5 protease inhibitor. Synonyms: (phenyldisulfanyl)benzene. Grades: 97 %. CAS No. 882-33-7. Molecular formula: C12H10S2. Mole weight: 218.34.
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