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Neomycin B is originally isolated from Str. fradiae 3535. It is mainly resistant to bacteria and mycobacteria, and its activity is the strongest of the three components. Synonyms: Framycetin; Mycifradin; Soframycin; Dekamycin II; O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?3)-O-β-D-ribofuranosyl-(1?5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine. Grades: ≥95%. CAS No. 119-04-0. Molecular formula: C23H46N6O13. Mole weight: 614.64.
Neomycin B Hexaacetate
Neomycin B Hexaacetate is an aminoglycoside antibiotic found in many topical medications. And neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. Uses: Anti-bacterial agents; protein synthesis inhibitors. Synonyms: O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1?3)-O-β-D-ribofuranosyl-(1?5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine Hexaacetate; Actilin Hexaacetate; Actiline Hexaacetate; Antibiotic 10676 Hexaacetate; Antibiotique EF 185 Hexaacetate; Dekamycin III Hexaacetate; Enterfram Hexaacetate; Fradiomycin B Hexaacetate; Framidal Hexaacetate; Framycetin Hexaacetate; Framycin Hexaacetate; Framygen Hexaacetate; Francetin Hexaacetate; Fraquinol Hexaacetate; Leo Red Dry Cow. Grades: 95%. Molecular formula: C23H46N6O13 6CH3COOH. Mole weight: 614.65.
Neomycin B-LP Acetate Salt Hydrate
Neomycin B-LP Acetate Salt Hydrate, a derivative of Neomycin which is an aminoglycoside antibiotic found in many topical medications and has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. Grades: 99.38% by HPLC. Molecular formula: C25H48N6O14 xC2H4O2 H2O. Mole weight: 656.68.
Neomycin B-LP Trifluoroacetic Acid Salt
As a derivative of NeomycinNeomyc, B-LP Trifluoroacetic Acid Salt is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. Molecular formula: C25H48N6O14 xC2HF3O2. Mole weight: 656.68.
Neomycin B Sulfate
Neomycin B Sulfate is the sulfate salt form of Neomycin B, an aminoglycoside antibiotic. Synonyms: O-2,6-Diamino-2,6-dideoxy-β-L-idopyranosyl-(1?3)-O-β-D-ribofuranosyl-(1?5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine Sulfate (1:1); Framycetin Sulphate; D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1?3)-O-β-D-ribofuranosyl-(1?5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-, sulfate (1:1); Neomycin B monosulfate; D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?4)-O-[O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1?3)-β-D-ribofuranosyl-(1?5)]-2-deoxy-, sulfate (1:1) (salt); Neomycin B, sulfate (1:1) (salt); NSC 156885. Grades: ≥95%. CAS No. 25389-98-4. Molecular formula: C23H46N6O13.H2O4S. Mole weight: 712.72.
Hexacarboxybenzyl Neomycin C
Hexa-carboxybenzyl Neomycin C is an intermediate in synthesizing Neomycin C Hexaacetate, which is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. Synonyms: O-2,6-Dideoxy-2,6-bis[[(phenylmethoxy)carbonyl]amino]-α-D-glucopyranosyl-(1?3)-O-β-D-ribofuranosyl-(1?5)-O-[2,6-dideoxy-2,6-bis[[(phenylmethoxy)carbonyl]amino]-α-D-glucopyranosyl-(1?4)]-2-deoxy-N1,N3-bis[(phenylmethoxy)carbonyl]-D-streptamine. CAS No. 1216950-86-5. Molecular formula: C71H82N6O25. Mole weight: 1419.44.
Hexacarboxybenzyl Neomycin C Hepta-acetate
Hexacarboxybenzyl Neomycin C Hepta-acetate is an intermediate in synthesizing Neomycin C Hexaacetate, which is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. Synonyms: (2R, 3R, 4R, 5R, 6R) -6- ( ( (1R, 2S, 3S, 4R, 6S) -3-Acetoxy-2- ( ( (2S, 3R, 4R, 5R) -3-acetoxy-5- (acetoxymethyl) -4- ( ( (2R, 3R, 4R, 5R, 6R) -4, 5-diacetoxy-3- ( ( (benzyloxy) carbonyl) amino) -6- ( ( ( (benzyloxy) carbonyl) amino) methyl) tetrahydro-2H-pyran-2-yl) oxy) tetrahydrofuran-2-yl) oxy) -4, 6-bis ( ( (benzyloxy) carbonyl) amino) cyclohexyl) oxy) -5- ( ( (benzyloxy) carbonyl) amino) -2- ( ( ( (benzyloxy) carbonyl) amino) methyl) tetrahydro-2H-pyran-3, 4-diyl Diacetate. Molecular formula: C85H96N6O32. Mole weight: 1713.69.
Neomycin Sulfate EP Impurity B (3-Acetylneamine)
An impurity of Neomycin, which is an aminoglycoside antibiotic found in many topical medications. Synonyms: 3-Acetylneamine; 3-N-acetyl-2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-d-glucopyranosyl)-d-streptamine (3-acetylneamine). Grades: > 95%. Molecular formula: C14H28N4O7. Mole weight: 364.4.
1,1-Thiocarbonyldi-2(1H)-pyridone
1,1-Thiocarbonyldi-2(1H)-pyridone is a reagent used in the synthesis of sulfur heterocycles via domino metal-mediated reactions. Also used as a reagent in the synthesis of Neomycin-?Neomycin dimer which displays high affinity for AT-Rich DNA Duplexes. Group: Biochemicals. Grades: Highly Purified. CAS No. 102368-13-8. Pack Sizes: 500mg, 1g. Molecular Formula: C11H8N2O2S, Molecular Weight: 232.26. US Biological Life Sciences.
Worldwide
1,6-Heptadiyne
1,6-Heptadiyne is a reactant used in the synthesis of neomycin-benzimidazole conjugates to be used for the recognition of HIV-TAR RNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 2396-63-6. Pack Sizes: 1g, 5g. Molecular Formula: C7H8, Molecular Weight: 92.14. US Biological Life Sciences.
Worldwide
2'''-acetyl-6'''-hydroxyneomycin C deacetylase
Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 3.5.1.112, 2'-N-acetylparomamine deacetylase. Group: Enzymes. Synonyms: neoL (gene name). Enzyme Commission Number: EC 3.5.1.113. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4393; 2'''-acetyl-6'''-hydroxyneomycin C deacetylase; EC 3.5.1.113; neoL (gene name). Cat No: EXWM-4393.
2-deoxy-scyllo-inosamine dehydrogenase
Requires zinc. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, neomycin and ribostamycin. cf. EC 1.1.99.38, 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent). Group: Enzymes. Synonyms: neoA (gene name); kanK (gene name, ambiguous); kanE (gene name, ambiguous). Enzyme Commission Number: EC 1.1.1.329. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0242; 2-deoxy-scyllo-inosamine dehydrogenase; EC 1.1.1.329; neoA (gene name); kanK (gene name, ambiguous); kanE (gene name, ambiguous). Cat No: EXWM-0242.
2-deoxy-scyllo-inosose synthase
Requires Co2+. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Requires an NAD+ cofactor, which is transiently reduced during the reaction. The enzyme from the bacterium Bacillus circulans forms a complex with the glutamine amidotransferase subunit of pyridoxal 5'-phosphate synthase (EC 4.3.3.6), which appears to stabilize the complex. Group: Enzymes. Synonyms: btrC (gene name); neoC (gene name); kanC (gene name). Enzyme Commission Number: EC 4.2.3.124. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5137; 2-deoxy-scyllo-inosose synthase; EC 4.2.3.124; btrC (gene name); neoC (gene name); kanC (gene name). Cat No: EXWM-5137.
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Unlike the enzyme from the bacterium Streptomyces kanamyceticus, which can also accept UDP-D-glucose (cf. EC 2.4.1.284, 2-deoxystreptamine glucosyltransferase), the enzyme from Bacillus circulans can only accept UDP-N-acetyl-α-D-glucosamine. Group: Enzymes. Synonyms: btrM (gene name); neoD (gene name); kanF (gene name). Enzyme Commission Number: EC 2.4.1.283. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2516; 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase; EC 2.4.1.283; btrM (gene name); neoD (gene name); kanF (gene name). Cat No: EXWM-2516.
2'-N-acetylparomamine deacetylase
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. The enzyme from the bacterium Streptomyces fradiae can also accept 2'''-acetyl-6'''-hydroxyneomycin C as substrate, cf. EC 3.5.1.113, 2'''-acetyl-6'''-hydroxyneomycin C deacetylase. Group: Enzymes. Synonyms: btrD (gene name); neoL (gene name); kanN (gene name). Enzyme Commission Number: EC 3.5.1.112. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4392; 2'-N-acetylparomamine deacetylase; EC 3.5.1.112; btrD (gene name); neoL (gene name); kanN (gene name). Cat No: EXWM-4392.
5''-phosphoribostamycin phosphatase
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin. No metal is required for activity. Group: Enzymes. Synonyms: btrP (gene name); neoI (gene name). Enzyme Commission Number: EC 3.1.3.88. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3694; 5''-phosphoribostamycin phosphatase; EC 3.1.3.88; btrP (gene name); neoI (gene name). Cat No: EXWM-3694.
6'''-Deamino-6'''-hydroxyneomycin C
6'''-Deamino-6'''-hydroxyneomycin C is an aminoglycoside antibiotic produced by Streptomyces fradiae UC 75. It has anti-gram-positive and negative bacteria activity. Synonyms: 6'''-hydroxyneomycin C; Neomycin Y2; (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside. Molecular formula: C23H45N5O14. Mole weight: 615.63.
6'''-hydroxyneomycin C oxidase
Contains FAD. Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. Works in combination with EC 2.6.1.95, neomycin C transaminase, to replace the 6'''-hydroxy group of 6'''-hydroxyneomycin C with an amino group.Also catalyses EC 1.1.3.43, paromamine 6'-oxidase. Group: Enzymes. Synonyms: neoG (gene name); neoQ (obsolete gene name). Enzyme Commission Number: EC 1.1.3.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0417; 6'''-hydroxyneomycin C oxidase; EC 1.1.3.44; neoG (gene name); neoQ (obsolete gene name). Cat No: EXWM-0417.
aminoglycoside 6'-N-acetyltransferase
The antibiotics kanamycin A, kanamycin B, neomycin, gentamicin C1a, gentamicin C2 and sisomicin are substrates. The antibiotic tobramycin, but not paromomycin, can also act as acceptor. The 6-amino group of the purpurosamine ring is acetylated. Group: Enzymes. Synonyms: aminoglycoside N6'-acetyltransferase; aminoglycoside-6'-acetyltransferase; aminoglycoside-6-N-acetyltransferase; kanamycin acetyltransferase. Enzyme Commission Number: EC 2.3.1.82. CAS No. 56467-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2263; aminoglycoside 6'-N-acetyltransferase; EC 2.3.1.82; 56467-65-3; aminoglycoside N6'-acetyltransferase; aminoglycoside-6'-acetyltransferase; aminoglycoside-6-N-acetyltransferase; kanamycin acetyltransferase. Cat No: EXWM-2263.
Bluensomycin
Bluensomycin is an amino glycoside antibiotic produced by Streptomyces bluensis var. bluensis. It has anti-gram-positive and negative bacteria activity, and is cross-resistant to streptomycin and neomycin B. Synonyms: Bluensomicina; Bluensin. Grades: >98%. CAS No. 11011-72-6. Molecular formula: C21H39N5O14. Mole weight: 585.56.
Cyclothialidine
It is produced by the strain of Streptomyces filipinensis NR 0484. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.3 μmol/L, and the reference neomycin was 1.2 μmol/L. Synonyms: Cyclothialidine A; (2S)-2-[[(5S,8R)-5-[[(2S,3R)-1-(2-amino-3-hydroxypropanoyl)-3-hydroxypyrrolidine-2-carbonyl]amino]-13,15-dihydroxy-16-methyl-2,6-dioxo3-oxa-10-thia-7-azabicyclo[10.4.0]hexadeca-1(16),12,14-triene-8-carbonyl]amino]propanoic acid; N-[[(4R,7S)-1,3,4,5,6,7,8,10-octahydro-12,14-dihydroxy-7-[[(3R)-3-hydroxy-1-L-seryl-L-prolyl]amino]-11-methyl-6,10-dioxo-9,2,5-benzoxathiaazacyclododecin-4-yl]carbonyl]-L-alanine. CAS No. 147214-63-9. Molecular formula: C26H35N5O12S. Mole weight: 641.65.
Cyclothialidine B
It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-76-1. Molecular formula: C25H33N5O11S. Mole weight: 611.62.
Cyclothialidine C
It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 161161-54-2. Molecular formula: C26H35N5O11S. Mole weight: 625.66.
Cyclothialidine D
It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-78-3. Molecular formula: C24H31N5O11S. Mole weight: 597.60.
Cyclothialidine E
It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-79-4. Molecular formula: C25H33N5O11S. Mole weight: 611.63.
Framycetin
Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a K i of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a K i of 13.5 μM. Framycetin, a 5"-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Neomycin B; Fradiomycin B. CAS No. 119-04-0. Pack Sizes: 25 mg (16.27 mM * 2.5 mL in 0.9% NaCl); 50 mg (16.27 mM * 5 mL in 0.9% NaCl); 100 mg (16.27 mM * 10 mL in 0.9% NaCl). Product ID: HY-17624.
Framycetin sulfate
Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a K i of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a K i of 13.5 μM. Framycetin sulfate, a 5"-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Neomycin B sulfate; Fradiomycin B sulfate. CAS No. 4146-30-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-17624A.
gentamicin 2'-N-acetyltransferase
The antibiotics gentamicin A, sisomicin, tobramycin, paromomycin, neomycin B, kanamycin B and kanamycin C can also act as acceptors. Group: Enzymes. Synonyms: gentamycin acetyltransferase II; gentamycin 2'-N-acetyltransferase; acetyl-CoA:gentamycin-C1a N2'-acetyltransferase. Enzyme Commission Number: EC 2.3.1.59. CAS No. 50864-40-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2238; gentamicin 2'-N-acetyltransferase; EC 2.3.1.59; 50864-40-9; gentamycin acetyltransferase II; gentamycin 2'-N-acetyltransferase; acetyl-CoA:gentamycin-C1a N2'-acetyltransferase. Cat No: EXWM-2238.
Inosamycin A
Inosamycin A is a broad-spectrum antimicrobial antibiotic originally isolated from Str. hygroscopicus No. J296-21. Its antibacterial activity was comparable to that of neomycin, and about twice that of ribomycin. Synonyms: Bu 2659A; 6-Amino-2-{[3-O- (2, 6-diamino-2, 6-dideoxyhexopyranosyl) pentofuranosyl]oxy}-3, 4-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxyhexopyranoside. CAS No. 91421-97-5. Molecular formula: C23H45N5O14. Mole weight: 615.63.
kanamycin kinase
Also acts on the antibiotics neomycin, paromomycin, neamine, paromamine, vistamycin and gentamicin A. An enzyme from Pseudomonas aeruginosa also acts on butirosin. Group: Enzymes. Synonyms: neomycin-kanamycin phosphotransferase. Enzyme Commission Number: EC 2.7.1.95. CAS No. 62213-36-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3125; kanamycin kinase; EC 2.7.1.95; 62213-36-9; neomycin-kanamycin phosphotransferase. Cat No: EXWM-3125.
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Also catalyses EC 2.6.1.101, L-glutamine:5-amino-2,3,4-trihydroxycyclohexanone aminotransferase. Group: Enzymes. Synonyms: btrR (gene name); neoB (gene name); kanB (gene name). Enzyme Commission Number: EC 2.6.1.100. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2840; L-glutamine:2-deoxy-scyllo-inosose aminotransferase; EC 2.6.1.100; btrR (gene name); neoB (gene name); kanB (gene name). Cat No: EXWM-2840.
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Also catalyses EC 2.6.1.100, L-glutamine:2-deoxy-scyllo-inosose aminotransferase. Group: Enzymes. Enzyme Commission Number: EC 2.6.1.101. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2841; L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase; EC 2.6.1.101. Cat No: EXWM-2841.
N2-[ (Phenylmethoxy) carbonyl]-L-glutamine
N2-[ (Phenylmethoxy) carbonyl]-L-glutamine has use an anti-ulcer agent. Also an inhibitor for AHAS (Acetohydroxy Acid Synthase) an important enzyme which will affect how benign an environmental herbicide is. Also used in the synthesis of neomycin B, an important HIV antiviral agent. Group: Biochemicals. Alternative Names: N2-Carboxy-glutamine N-Benzyl Ester; L-N2-Carboxyglutamine N2-Benzyl Ester; (Benzyloxycarbonyl) glutamine; Carbobenzoxy-L-glutamine; N-(Benzyloxycarbonyl)-L-glutamine; N- (Benzyloxycarbonyl) glutamine; N-Carbobenzoxy-L-glutamine; N2-Benzoxycarbonyl-L-glutamine; N2-Benzyloxycarbonyl-L-glutamine; N2-Carbobenzoxy-L-glutamine; NSC 186903; Nα-Benzyloxycarbonyl-L-glutamin. Grades: Highly Purified. CAS No. 2650-64-8. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Neamine Disulfate
An impurity of Neomycin, which is an aminoglycoside antibiotic found in many topical medications. Synonyms: D-Streptamine, 2-deoxy-4-O-(2,?6-diamino-2,?6-dideoxy-α-D-gulopyranosyl)?-, sulfate (1:2) (salt) (9CI). Grades: > 95%. CAS No. 71155-47-0. Molecular formula: C12H26N4O6. 2 H2O4S. Mole weight: 322.36 2 98.08.
Neamine Disulfate Salt
Neamine is normally found as a core structure of aminoglycoside antibiotics. It is used in the synthesis of disaccharide neamine derivatives as antibacterial agents. Synonyms: 2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine Disulfate Salt; Neomycin A Disulfate Salt. Grades: 97%. Molecular formula: C12H30N4O14S2. Mole weight: 518.52.
Neamine hydrochloride
Neamine hydrochloride is a biomedical substance used for studying various bacterial infections. It is derived from aminoglycoside antibiotics. Synonyms: 2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-D-streptamine hydrochloride; Neomycin A tetrahydrochloride. Grades: 95%. CAS No. 15446-43-2. Molecular formula: C12H26N4O6 4HCl. Mole weight: 468.20.
neamine phosphoribosyltransferase
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin. The enzyme requires a divalent metal ion, optimally Mg2+, Ni2+ or Co2+. Group: Enzymes. Synonyms: btrL (gene name); neoM (gene name). Enzyme Commission Number: EC 2.4.2.49. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2678; neamine phosphoribosyltransferase; EC 2.4.2.49; btrL (gene name); neoM (gene name). Cat No: EXWM-2678.
Neamine tetrahydrochloride
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 15446-43-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-115349.
neamine transaminase
The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin B, butirosin, neomycin and ribostamycin. Works in combination with EC 1.1.3.43, paromamine 6-oxidase, to replace the 6'-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces kanamyceticus can also catalyse EC 2.6.1.94, 2'-deamino-2'-hydroxyneamine transaminase, which leads to production of kanamycin A. The enzyme from the bacterium Streptomyces fradiae can also catalyse EC 2.6.1.95, leading to production of neomycin C. Group: Enzymes. Synonyms: glutamate-6'-dehydroparomamine aminotransferase; btrB (gene name); neoN (gene name); kacL (gene name). Enzyme Commission Number: EC 2.6.1.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2934; neamine transaminase; EC 2.6.1.93; glutamate-6'-dehydroparomamine aminotransferase; btrB (gene name); neoN (gene name); kacL (gene name). Cat No: EXWM-2934.
Neomycin
Neomycin is an aminoglycoside antibiotic found in many topical medications. Synonyms: o-2,6-diamino-2,6-dideoxy-.beta.-l-idopyranosyl-(1.->3)-o-.beta.-d-ribofuranosyl-(1->5)]-o-[2,6-diamino-2,6-dideoxy-.alpha.-d-glucopyranosyl-(1->4)]-2-deoxy sulfate. Grades: > 95%. CAS No. 1404-04-2. Molecular formula: C23H46N6O13. Mole weight: 614.66.
Neomycin C
Neomycin C is originally isolated from Str. fradiae 3535. It is mainly resistant to bacteria and mycobacteria. Synonyms: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside. Grades: 99%. CAS No. 66-86-4. Molecular formula: C23H46N6O13. Mole weight: 614.64.
Neomycin C Hexaacetate
Neomycin C Hexaacetate is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. Synonyms: O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?3)-O-β-D-ribofuran osyl-(1?5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine Hexaacetate; Dekamycin II Hexaacetate. Grades: 96%. Molecular formula: C23H46N6O13 6CH3COOH. Mole weight: 614.65.
neomycin C transaminase
The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. Works in combination with EC 1.1.3.44, 6'''-hydroxyneomycin C oxidase, to replace the 6'''-hydroxy group of 6'''-deamino-6'''-hydroxyneomycin C with an amino group.The enzyme, characterized from the bacterium Streptomyces fradiae, can also catalyse EC 2.6.1.93, neamine transaminase. Group: Enzymes. Synonyms: neoN (gene name). Enzyme Commission Number: EC 2.6.1.95. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2936; neomycin C transaminase; EC 2.6.1.95; neoN (gene name). Cat No: EXWM-2936.
Neomycin solution
Neomycin solution. Group: Biochemicals. Grades: Highly Purified. CAS No. 119-04-0. Pack Sizes: 20g. US Biological Life Sciences.
Worldwide
Neomycin sulfate
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1405-10-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0470.
Neomycin sulfate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metaboliteseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: Neomycin sulphate, Quintess-N, Otobiotic,Neomycin, sulfate (salt), Fradiomycin sulfate, Tuttomycin, Myacine, Mycifradin N, Lidamycin Creme, Myciguent, Neomycin sulfate, Mycifradin, Nivemycin, Mycerin sulfate, Biosol, Bykomycin, Neomix, Neosulf, New France F, Neobrettin, Neo-Mantle Creme, Neolate, Endomixin, Neofracin.
Neomycin sulfate
United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Group: Pharmacopeia & metrological institutes standards; pharma & vet compounds & metabolites; standards for environmental regulatory methods; pharma & vet compounds & metabolites; european pharmacopoeia (ph. eur.); pharmacopoeial standards. Alternative Names: Neomycin sulphate, Quintess-N, Otobiotic,Neomycin, sulfate (salt), Fradiomycin sulfate, Tuttomycin, Myacine, Mycifradin N, Lidamycin Creme, Myciguent, Neomycin sulfate, Mycifradin, Nivemycin, Mycerin sulfate, Biosol, Bykomycin, Neomix, Neosulf, New France F, Neobrettin, Neo-Mantle Creme, Neolate, Endomixin, Neofracin. CAS No. 1405-10-3. Pack Sizes: 200MG. Molecular formula: C23H52N6O25S3. Mole weight: 908.88. Catalog: APS1405103. Format: Neat.
Neomycin Sulfate
Aminoglycoside antibiotic that inhibits translation by binding to the small subunit of prokaryotic ribosomes. Inhibitor of phospholipase C due to binding to inositol phospholipids. Neomycin inhibits phosphatidylcholine-phospholipase D activity. Blocks voltage sensitive Ca2+ channels without affecting Na+/Ca2+ antiporter in nerve cells. Group: Biochemicals. Grades: Cell Culture Grade. CAS No. 1405-10-3. Pack Sizes: 100g, 500g, 1Kg. Molecular Formula: C23H46N6O13 3H2SO4, Molecular Weight: 908.9. US Biological Life Sciences.
Worldwide
Neomycin Sulfate EP Impurity C
An impurity of Neomycin, which is an aminoglycoside antibiotic found in many topical medications. Synonyms: 4-O-(2-amino-2-deoxy-d-glucopyranosyl)-2-deoxy-d-streptamine (paromamine or neomycin D). Grades: > 95%. Molecular formula: C23H46N6O13. Mole weight: 614.66.
Neomycin Sulfate EP Impurity E
An impurity of Neomycin, which is an aminoglycoside antibiotic found in many topical medications. Synonyms: 5-amino-2-(aminomethyl)-6-((5-((3,5-diamino-2-((3-amino-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)tetrahydro-2H-pyran-3,4-diol. Grades: > 95%. Molecular formula: C23H46N5O14. Mole weight: 616.65.
Neomycin Sulfate EP Impurity F
An impurity of Neomycin, which is an aminoglycoside antibiotic found in many topical medications. Synonyms: 5-amino-2-(aminomethyl)-6-((5-((3,5-diamino-2-((3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)tetrahydro-2H-pyran-3,4-diol. Grades: > 95%. Molecular formula: C23H47N6O13. Mole weight: 615.66.
Neomycin Sulfate EP Impurity G
An impurity of Neomycin, which is an aminoglycoside antibiotic found in many topical medications. Synonyms: N-(5-amino-2-((3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-3-((4-((3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4-hydroxycyclohexyl)acetamide. Grades: > 95%. CAS No. 54617-40-2. Molecular formula: C25H48N6O14. Mole weight: 656.69.
Neomycin Sulfate Solution 50mg/ml
Neomycin Sulfate, 50mg/ml Solution is a convenient, ready to use concentrate which inhibits protein synthesis via ribosomal binding mechanism. Group: Biochemicals. Alternative Names: Streptomyces fradiae waksman. Grades: Cell Culture Grade. CAS No. 1405-10-3. Pack Sizes: 5x20ml, 20x20ml. Molecular Formula: C23H46N6O13 3H2SO4, Molecular Weight: 908.9. US Biological Life Sciences.
Worldwide
Neomycin trisulfate
Neomycin trisulfate is an aminoglycoside antibiotic. It can be used to prevent and treat gastrointestinal infections caused by gram-negative bacteria such as Salmonella and Escherichia coli. Synonyms: (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)tetrahydro-2H-pyran-3,4-diol trisulfate; Framycetin sulfate; (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-b-L-idopyranosyl)-b-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-a-D-glucopyranoside trisulfate salt. CAS No. 879480-48-5. Molecular formula: C23H46N6O13.3H2SO4. Mole weight: 908.88.
Neomycin trisulfate hydrate
Neomycin trisulfate hydrate. Group: Biochemicals. Alternative Names: Neomycin Sulfate. Grades: Highly Purified. CAS No. 1405-10-3,1404-04-2. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C23H46N6O13·3H2SO4·xH2 O. US Biological Life Sciences.
Neomycin trisulfate salt hydrate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FradioMycin Sulfate; Neomycin Sulphate; Neomycin trisulfate salt hydrate; Neomycin Sulfate; Neomycin sulfate. Appearance: White or off-white powder. CAS No. 1405-10-3. Molecular formula: C23H46N6O13·3H2SO4·xH2O. Mole weight: 908.88 (anhydrous basis). Purity: 95%+. IUPACName: Fradiomycin Sulfate. Product ID: ACM1405103. Alfa Chemistry ISO 9001:2015 Certified.
paromamine 6'-oxidase
Contains FAD. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Works in combination with EC 2.6.1.93, neamine transaminase, to replace the 6'-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 1.1.3.44, 6'''-hydroxyneomycin C oxidase. Group: Enzymes. Synonyms: btrQ (gene name); neoG (gene name); kanI (gene name); tacB (gene name); neoQ (obsolete gene name). Enzyme Commission Number: EC 1.1.3.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0416; paromamine 6'-oxidase; EC 1.1.3.43; btrQ (gene name); neoG (gene name); kanI (gene name); tacB (gene name); neoQ (obsolete gene name). Cat No: EXWM-0416.
Paromomycin II
It is produced by the strain of Str. rimosus forma paromomycinus NRRL 2455. It's an aminoglycoside antibiotic. It has activity against gram-positive, negative bacteria, mycobacterium and protozoa. It has good curative effect for amebic dysentery and a few bacillary dysentery. Synonyms: Zygomycin A2; Neomycin F; Aminosidin II; Aminosidine II; Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-3)-beta-D-ribofuranosyl-(1-5))-2-deoxy-; 4-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-β-D-ribofuranosyl]-2-deoxy-D-streptamine; Framycetin EP Impurity F. Grades: ≥95%. CAS No. 51795-47-2. Molecular formula: C23H45N5O14. Mole weight: 615.63.
Paromomycin sulfate
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Aminosidine sulfate. CAS No. 1263-89-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0956.
Paromomycin Sulfate
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Paromomycin sulfate salt. Product Category: Inhibitors. CAS No. 1263-89-4. Molecular formula: C23H47N5O18S. Mole weight: 713.7. Purity: ≥98.0%. Product ID: ACM1263894. Alfa Chemistry ISO 9001:2015 Certified.
Paulomycin A
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacteria effect, and it has inhibitory effect on staphylococcus aureus resistant to penicillin, streptomycin, neomycin and macrolide antibiotics. The antibacterial activity of Paulomycin A, A1 and B are stronger than other components. Synonyms: 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(1S)-1-[(2S)-2-methyl-1-oxobutoxy]ethyl]-α-L-lyxo-hexopyranosyl]-4-O-[(Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-. CAS No. 81988-77-4. Molecular formula: C34H46N2O17S. Mole weight: 786.80.
Paulomycin A2
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacteria effect, and it has inhibitory effect on staphylococcus aureus resistant to penicillin, streptomycin, neomycin and macrolide antibiotics. The antibacterial activity of Paulomycin A, A1 and B are stronger than other components. Synonyms: 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(S)-1-(3-methyl-1-oxobutoxy)ethyl]-α-L-lyxo-hexopyranosyl]-4-O-[(Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-. CAS No. 101411-68-1. Molecular formula: C34H46N2O17S. Mole weight: 786.80.
Paulomycin B
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacteria effect, and it has inhibitory effect on staphylococcus aureus resistant to penicillin, streptomycin, neomycin and macrolide antibiotics. The antibacterial activity of Paulomycin A, A1 and B are stronger than other components. Synonyms: 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(1S)-1-(2-methyl-1-oxopropoxy)ethyl]-α-L-lyxo-hexopyranosyl]-4-O-[(Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-. CAS No. 81988-76-3. Molecular formula: C33H44N2O17S. Mole weight: 772.77.
PROTO-1
PROTO-1, a benzothiophene carboxamide, shows significant protection of hair cells over a broad range of neomycin concentrations, from 25 μM to 400 μM. Synonyms: 2-[(4-chlorophenyl)carbamoylamino]-6-ethyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamidePROTO-1; PROTO1; PROTO 1ST50928294CBMicro_046627AC1LLLR7Opr ea1_608416SCHEMBL2682306. CAS No. 312951-85-2. Molecular formula: C17H19ClN4O2S. Mole weight: 378.88.
Senfolomycin A
It is produced by the strain of Str. ochrosporus NRRL 3146. It has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, streptomycin, neomycin, macrolide antibiotics. It also has weaker effect of anti-Gram-negative bacteria. Synonyms: Paulomycin E; 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-(4-C-acetyl-2,6-dideoxy-3-O-methyl-a-L-xylo-hexopyranosyl)-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-butenyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; Antibiotic LL RA 6950BA. CAS No. 11017-36-0. Molecular formula: C29H36N2O16S. Mole weight: 700.66.
Senfolomycin B
It is produced by the strain of Str. ochrosporus NRRL 3146. It has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, streptomycin, neomycin, macrolide antibiotics. It also has weaker effect of anti-Gram-negative bacteria. Synonyms: Paulomycin F; 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-4-C-(1-hydroxyethyl)-3-O-methyl-α-L-xylo-hexopyranosyl]-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; Antibiotic LL RA 6950BB. CAS No. 11031-56-4. Molecular formula: C29H38N2O16S. Mole weight: 702.68.
TDP-b-L-rhamnose ammonium salt
TDP-b-L-rhamnose ammonium salt is a key intermediate product utilized in the synthesis of rhamnose-containing antibiotics. This compound is essential in the production of drugs like the aminoglycoside antibiotics; neomycin, paromomycin, and lividomycin. Its main role is to catalyze the formation of the rhamnose sugar moiety in these antibiotics, essential for their antibiotic activity. Molecular formula: C16H32N4O16P2. Mole weight: 598.39.
Involved in biosynthesis of the aminoglycoside antibiotic neomycin. Requires a divalent metal ion, optimally Mg2+, Mn2+ or Co2+. Group: Enzymes. Synonyms: neoK (gene name). Enzyme Commission Number: EC 2.4.1.285. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2518; UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase; EC 2.4.1.285; neoK (gene name). Cat No: EXWM-2518.
Neomycin sulfate
100g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C23H46N6O13 · xH2SO4. CAS No. 1405-10-3. Prepack ID 20446840-100g. Molecular Weight 908.88. See USA prepack pricing.
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