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Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research [1]. Niclosamide is a STAT3 inhibitor with an IC 50 of 0.25 μM in HeLa cells [4]. Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY2353. CAS No. 50-65-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0497.
Niclosamide
Niclosamide. CAS No: 50-65-7
Sarchem Laboratories New Jersey NJ
Niclosamide
Niclosamide. Group: Biochemicals. Grades: Purified. CAS No. 50-65-7. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Niclosamide
Niclosamide is an oral antihelminthic drug, which has been used to treat tapeworm infection for about 50 years. Niclosamide is also used as a molluscicide for water treatment in schistosomiasis control programs. Recently, several groups have independently discovered that niclosamide is also active against cancer cells. Evidence supports that niclosamide targets multiple signaling pathways (NF-κB, Wnt/β-catenin, Notch, ROS, mTORC1, and Stat3), most of which are closely involved with cancer stem cells. Given its potential antitumor activity, clinical trials for niclosamide and its derivatives are warranted for cancer treatment. It can be used for tapeworm disease in livestock and poultry, and fasciasis in ruminants. Uses: Anticestodal agents; antinematodal agents; molluscacides. Synonyms: Niclosamide, Clonitralide, Fenasal, BAY 2353, NSC 178296, WR 46234, BAY-2353, NSC-178296, WR-46234, BAY2353, NSC178296, WR46234. Grades: >98%. CAS No. 50-65-7. Molecular formula: C13H8Cl2N2O4. Mole weight: 327.12.
Isotope labelled Niclosamide is used as an anthelmintic drug (Cestodes). Group: Biochemicals. Grades: Highly Purified. CAS No. 1325559-12-3. Pack Sizes: 500ug, 5mg. Molecular Formula: C713C6H8Cl2N2O4, Molecular Weight: 333.08. US Biological Life Sciences.
A STAT3 signaling pathway inhibitor. Niclosamide potently inhibits the activation and transcriptional function of STAT3 and induces cell growth inhibition, apoptosis, and cell cycle arrest of cancer cells with constitutively active STAT3. Also reversibly inhibits mTORC1 signaling and stimulates auto. Group: Biochemicals. Grades: Highly Purified. CAS No. 50-65-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Niclosamide ethanolamine salt
Niclosamide is an oral antihelminthic drug, which has been used to treat tapeworm infection for about 50 years. Niclosamide is also used as a molluscicide for water treatment in schistosomiasis control programs. Recently, several groups have independently discovered that niclosamide is also active against cancer cells. Evidence supports that niclosamide targets multiple signaling pathways (NF-κB, Wnt/β-catenin, Notch, ROS, mTORC1, and Stat3), most of which are closely involved with cancer stem cells. Given its potential antitumor activity, clinical trials for niclosamide and its derivatives are warranted for cancer treatment. Synonyms: BAY-73; BAY-6076; Bayluscide; HL 2448; Clonitralid; Niclosamide-olamine; Niclosamidel. Grades: ≥98%. CAS No. 1420-04-8. Molecular formula: C13H8Cl2N2O4·C2H7NO. Mole weight: 388.2.
Niclosamide Ethanolamine Salt
Niclosamide Ethanolamine Salt is an ethanolamine salt of Niclosamide (N395500), which is used as an anthelmintic drug (Cestodes). Group: Biochemicals. Grades: Highly Purified. CAS No. 1420-04-8. Pack Sizes: 50mg, 100mg. Molecular Formula: C13H8Cl2N2O4; C2H7NO. US Biological Life Sciences.
Worldwide
Niclosamide monohydrate
Niclosamide monohydrate. Group: Biochemicals. Alternative Names: 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide hydrate; 2',5-D733ichloro-4'-nitrosalicylanilide hydrate; Bayluscid. Grades: Highly Purified. CAS No. 73360-56-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C13H10Cl2N2O5. US Biological Life Sciences.
Worldwide
Niclosamide monohydrate
Niclosamide Monohydrate is used for the treatment of most tapeworm infections by inhibiting DNA replication. It inhibits the TNF-induced NF-κB reporter activity in a dose- and time-dependent manner in U2OS cells. It also inhibits TNF-induced degradation of IκBα and relocation of p65 in a dose- and time-dependent manner in HL-60, Molm13, or AML primary cells. Synonyms: Niclocide monohydrate; BAY2353 monohydrate; BAY 2353 monohydrate; BAY-2353 monohydrate; Cestocid monohydrate; Sagimid monohydrate; Yomesan monohydrate. Grades: >98%. CAS No. 73360-56-2. Molecular formula: C13H10Cl2N2O5. Mole weight: 345.13.
Niclosamide olamine
Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research [1]. Niclosamide olamin is a STAT3 inhibitor with an IC 50 of 0.25 μM in HeLa cells [4]. Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY2353 olamine. CAS No. 1420-04-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0497C.
Niclosamide (Standard) is the analytical standard of Niclosamide. This product is intended for research and analytical applications. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research [1]. Niclosamide is a STAT3 inhibitor with an IC 50 of 0.25 μM in HeLa cells [4]. Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-65-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0497R.