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| Product | Description | |
|---|---|---|
| Nilotinib | Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMN107. CAS No. 641571-10-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10159. |  |
| Nilotinib 3-Imidazolyl N-Difluoroboryloxide | Nilotinib 3-Imidazolyl N-Difluoroboryloxide. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS002584. Format: Neat. |  |
| Nilotinib 3-Imidazolyl N-oxide | Nilotinib 3-Imidazolyl N-oxide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2139382-75-3. IUPAC Name: 4-methyl-N-[3-(4-methyl-3-oxo-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzamide. Molecular formula: C28H22F3N7O2. Mole weight: 545.52. Catalog: APS2139382753. SMILES: Cc1ccc(cc1Nc2nccc(n2)c3cccnc3)C(=O)Nc4cc(cc(c4)C(F)(F)F)n5cc(C)n(=O)c5. Format: Neat. | |
| Nilotinib-d3 | Labeled analog of Nilotinib (AMN1O7), which might be useful in treatment of chronic myelogenous leukemia. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4- (methyl-d3) -1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] benzamide; AMN 107-d3; Tasigna-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Nilotinib-[d3] | Nilotinib-[d3] is the Labelled analog of Nilotinib, which may be used to treat chronic myelogenous leukemia. Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM. Synonyms: Nilotinib D3; 4-Methyl-N-{3-[4-(2H3)methyl-1H-imidazol-1-yl]-5-(trifluoromethyl)phenyl}-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide. Grade: 97%; 98% atom D. CAS No. 1215678-43-5. Molecular formula: C28H19D3F3N7O. Mole weight: 532.53. |  |
| Nilotinib-[d6] | Nilotinib-[d6] is the Labelled analog of Nilotinib, which may be used to treat chronic myelogenous leukemia. Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM. Synonyms: Nilotinib D6; 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide-d6. Grade: 95% by HPLC; 95% atom D. CAS No. 1268356-17-7. Molecular formula: C28H16D6F3N7O. Mole weight: 535.55. | |
| Nilotinib EP Impurity B | Nilotinib EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18595-18-1. Molecular formula: C9H11NO2. Mole weight: 165.19. Catalog: APB18595181. | |
| Nilotinib, Free Base (AMN107) | Nilotinib, a novel, selective BCR-ABL inhibitor, fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib. Nilotinib is not only more potent than imatinib against wild-type BCR-ABL (IC50 < 30nM), but also significantly active against 32/33 imatinib-resistant BCR-ABL mutants. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] benzamide; AMN107; Tasigna. Grades: Highly Purified. CAS No. 641571-10-0. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Nilotinib monohydrochloride monohydrate | Nilotinib monohydrochloride monohydrate is a second generation tyrosine kinase inhibitor (TKI), is significantly potent against BCR-ABL, and is active against many BCR-ABL mutants. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMN107 monohydrochloride monohydrate. CAS No. 923288-90-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10159A. | |
| Nilotinib N-Oxide | A metabolite of Nilotinib. Group: Biochemicals. Alternative Names: 4-Methyl-N- [3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl] -3- [ [4- (3-pyridinyl-N-oxide) -2-pyrimidinyl] amino] benzamide. Grades: Highly Purified. CAS No. 1246817-85-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline | 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline is a reactant used in the synthesis of novel Bcr/Abl inhibitors as anti-cancer drugs. Nilotinib (N465300) impurity, which might be useful in treatment of chronic myelogenous leukemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 943320-48-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H8F3N3, Molecular Weight: 227.19. US Biological Life Sciences. | Worldwide |
| 3- (2, 4-Dimethyl-1H-imidazol-1-yl) -5- (trifluoromethyl) aniline | 3- (2, 4-Dimethyl-1H-imidazol-1-yl) -5- (trifluoromethyl) aniline is a reactant used in various organic and pharmaceutical syntheses. Nilotinib (N465300) impurity, which might be useful in treatment of chronic myelogenous leukemia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 500mg. Molecular Formula: C12H12F3N3, Molecular Weight: 255.24. US Biological Life Sciences. | Worldwide |
| 3- (2-Methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) aniline | 3- (2-Methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) aniline is used in the preparation of cinnamaldehyde derivatives as inhibitors of bacterial cell division. Nilotinib (N465300) impurity, which might be useful in treatment of chronic myelogenous leukemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 641571-06-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C11H10F3N3, Molecular Weight: 241.21. US Biological Life Sciences. | Worldwide |
| 3- (4-Ethyl-1H-imidazol-1-yl) -5- (trifluoromethyl) aniline | 3- (4-Ethyl-1H-imidazol-1-yl) -5- (trifluoromethyl) aniline is an impurity of Nilotinib (N465300), a tyrosine kinase inhibitor and an anticancer agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H12F3N3, Molecular Weight: 255.24. US Biological Life Sciences. | Worldwide |
| 3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline | Intermediate in the preparation of Nilotinib. Group: Biochemicals. Alternative Names: 3- (4-Methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) benzenamine; 1-(3-Amino-5-trifluoromethylphenyl)-4-methylimidazole. Grades: Highly Purified. CAS No. 641571-11-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3 | Intermediate in the preparation of labeled Nilotinib. Group: Biochemicals. Alternative Names: 3- (4-Methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) benzenamine-d3; 1-(3-Amino-5-trifluoromethylphenyl)-4-methylimidazole-d3. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine | An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 36 nM. Synonyms: 641571-16-6; 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine3-(5-methylimidazol-1-yl)-5-(trifluoromethyl)aniline3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilinestarbld0029650. CAS No. 641571-16-6. Molecular formula: C11H10F3N3. Mole weight: 241.217. | |
| 3-Acetylpyridine N-Oxide | 3-Acetylpyridine N-Oxide is an intermediate in synthesizing Nilotinib N-Oxide (N465310), which is a metabolite of Nilotinib (N465300). Group: Biochemicals. Grades: Highly Purified. CAS No. 14188-94-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C7H7NO2. US Biological Life Sciences. | Worldwide |
| 3-Bromo-5-nitrobenzotrifluoride | 3-Bromo-5-nitrobenzotrifluoride is an efficient D-glucosamine-based copper catalyst for C-X couplings and its application in synthesis of nilotinib intermediate. 3-Bromo-5-nitrobenzotrifluoride is also an intermediate for Nilotinib (N465300). Group: Biochemicals. Grades: Highly Purified. CAS No. 630125-49-4. Pack Sizes: 1g, 5g. Molecular Formula: C7H3BrF3NO2, Molecular Weight: 270. US Biological Life Sciences. | Worldwide |
| 3-Iodo-4-methyl-N-[3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl]benzamide | Intermediate in the preparation of Nilotinib. Group: Biochemicals. Grades: Highly Purified. CAS No. 926922-18-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 3-Iodo-4-methyl-N-[3- (4-methyl-1H-imidazol-1-yl) -5- (trifluoromethyl) phenyl]benzamide-d3 | Intermediate in the preparation of labeled Nilotinib. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-(2-Pyridinyl)-2-pyrimidinamine | Intermediate in the preparation of Nilotinib. Group: Biochemicals. Grades: Highly Purified. CAS No. 66521-65-1. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 4-(3-Pyridinyl)-2-pyrimidinamine | Intermediate in the preparation of Nilotinib. Group: Biochemicals. Alternative Names: 2-Amino-4-(3-pyridinyl)pyrimidine; 4-(3-Pyridyl)-2-pyrimidinamine; 4-(Pyridin-3-yl)pyrimidin-2-amine. Grades: Highly Purified. CAS No. 66521-66-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid | 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is an intermediate of Nilotinib, which is a Bcr-Abl inhibitor used to treat chronic myelogenous leukemia (CML). Synonyms: 4-Methyl-3-((4-(3-pyridyl)pyrimidin-2-yl)amino)benzoic acid; Nilotinib Hydrochloride Monohydrate Impurity D; Nilotinib Impurity D. Grade: ≥98%. CAS No. 641569-94-0. Molecular formula: C17H14N4O2. Mole weight: 306.32. | |
| 4-Methyl-3- ( (4- (3-pyridinyl) -2-pyrimidinyl) amino) -N- (5- (4-methyl-1H-imidazol-1-yl) -3- (trifluoromethyl) phenyl) benzamide | 4-Methyl-3- ( (4- (3-pyridinyl) -2-pyrimidinyl) amino) -N- (5- (4-methyl-1H-imidazol-1-yl) -3- (trifluoromethyl) phenyl) benzamide. Group: Biochemicals. Alternative Names: Nilotinib. Grades: Highly Purified. CAS No. 641571-10-0. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C28H22F3N7O. US Biological Life Sciences. | Worldwide |
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