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Nilvadipine. Group: Biochemicals. Alternative Names: 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-(1-methylethyl) ester, FR-34235, SKF-102362, escor. Grades: Highly Purified. CAS No. 75530-68-6. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C19H19N3O6. US Biological Life Sciences.
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Nilvadipine
Nilvadipine is a potent calcium channel antagonist, and the IC 50 value is around 0.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FK235; FR34235. CAS No. 75530-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14284.
Used as an antihypertensive and antianginal. Nilvadipine is prescribed for patients with both hypertension and chronic major cerebral artery occlusion. In hypertensive patients with high risk of atherosclerosis, nilvadipine may protect LDL cholesterol from in vivo oxidation. Nilvadipine reduces infarction foci, improves cerebral microcirculation, but does not affect the systemic arterial blood pressure. Pathohistochemical studies have revealed that the volume of the infarction in the middle cerebral artery occlusion model could be decreased by nilvadipine. Although it is a dihydropyridine derivative, nilvadipine has several kinetic, dynamic, and therapeutic effects that are different from even those of the other voltage-dependent Ca2+ channel blockers belonging to the same class. Nilvadipine could easily be transmitted to the central nervous system. Moreover, vascular smooth muscles contracted by potassium were reported to be inhibited by nilvadipine. It antagonizes both L- and T-type Group: Biochemicals. Alternative Names: 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-(1-Methylethyl) Ester, FR-34235, SKF-102362, Escor. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Nilvadipine-[d3]
Nilvadipine-[d3] is the labelled analogue of Nilvadipine, which is a potent calcium channel blocker with an IC50 of 0. 03 nM. Synonyms: Nilvadipine D3; 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-(Methyl-d3) 5-(1-methylethyl) Ester. Grade: 95% by HPLC; 95% atom D. CAS No. 95326-14-0. Molecular formula: C19H16D3N3O6. Mole weight: 388.39.
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