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| Product | Description | |
|---|---|---|
| nucleotidase | A wide specificity for 2', 3'- and 5'- nucleotides; also hydrolyses glycerol phosphate and 4-nitrophenyl phosphate. Group: Enzymes. Synonyms: nucleotide phosphatase; nucleotide-specific phosphatase; NSP I; NSP II; deoxyribonucleoside-activated nucleotidase (DAN); deoxyinosine-activated nucleotidase (DIAN); acid nucleotidase. Enzyme Commission Number: EC 3.1.3.31. CAS No. 9033-33-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3634; nucleotidase; EC 3.1.3.31; 9033-33-4; nucleotide phosphatase; nucleotide-specific phosphatase; NSP I; NSP II; deoxyribonucleoside-activated nucleotidase (DAN); deoxyinosine-activated nucleotidase (DIAN); acid nucleotidase. Cat No: EXWM-3634. |  |
| 3'(2'),5'-bisphosphate nucleotidase | Also acts on 3'-phosphoadenylyl sulfate, and on the corresponding 2'-phosphates. Group: Enzymes. Synonyms: phosphoadenylate 3'-nucleotidase; 3'-phosphoadenylylsulfate 3'-phosphatase; 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase. Enzyme Commission Number: EC 3.1.3.7. CAS No. 9025-83-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3674; 3'(2'),5'-bisphosphate nucleotidase; EC 3.1.3.7; 9025-83-6; phosphoadenylate 3'-nucleotidase; 3'-phosphoadenylylsulfate 3'-phosphatase; 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase. Cat No: EXWM-3674. | |
| 3'-nucleotidase | Wide specificity for 3'-nucleotides. Group: Enzymes. Synonyms: 3'-mononucleotidase; 3'-phosphatase; 3'-ribonucleotidase. Enzyme Commission Number: EC 3.1.3.6. CAS No. 9025-84-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3665; 3'-nucleotidase; EC 3.1.3.6; 9025-84-7; 3'-mononucleotidase; 3'-phosphatase; 3'-ribonucleotidase. Cat No: EXWM-3665. | |
| 5'-nucleotidase | Wide specificity for 5'-nucleotides. Group: Enzymes. Synonyms: uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase. Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. AMPase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3654; 5'-nucleotidase; EC 3.1.3.5; 9027-73-0; uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase. Cat No: EXWM-3654. | |
| 5'-Nucleotidase from Human, Recombinant | 5'-nucleotidase is an extracellular enzyme that converts nucleoside-5'-monophosphates to nucleosides with a substrate preference of AMP. Native 5'-nucleotidase is a GPI-anchored protein whose exporession is upregulated by hypoxia. 5'-nucleotidase has many functions in vivo including the generation of extracellular adenosine. 5'-Nucleotidase has various clinical significances. It is a key molecule in the regulation of cancer cells proliferation, migration and invasion in vitro tumor angiogenesis, and tumor immune escape in vivo. Due to this important role, the enzyme is a potential target for cancer research.1 It is also involved in salvage of extracellular nucleotides and...Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. Purity: >90% (SDS-PAGE). AMPase. Mole weight: ~61 kDa by SDS-PAGE (reducing). Activity: >15 U/mg. Storage: Store at -70°C. Form: Supplied as a solution containing Tris, NaCl, CaCl2, and 20% glycerol. Source: CHO cells. Species: Human. uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5; CD73; NT5E; ecto-5'-nucleotidase. Pack: vial of 6-12 μg. Cat No: NATE-0795. | |
| 5'-Nucleotidase from Microorganism | 5'-nucleotidase is an enzyme with system name 5'-ribonucleotide phosphohydrolase. This enzyme catalyses the following chemical reaction:a 5'-ribonucleotide + H2O? a ribonucleoside + phosphate. This enzyme has a wide specificity for 5'-nucleotides. Group: Enzymes. Synonyms: uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5. Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. Activity: >50U/mg protein. Storage: Store at -20°C. Form: White amorphous powder. Source: Microorganism. uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5; 5'NT. Cat No: NATE-1717. | |
| 5-Nucleotidase, Microorganism | 5-Nucleotidase, Microorganism (CD73) is an intrinsic membrane glycoprotein present as an ectoenzyme. 5-Nucleotidase catalyzes hydrolysis of 5-nucleotides to their corresponding nucleosides [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CD73; 5-NT. CAS No. 9027-73-0. Pack Sizes: 200 U; 500 U. Product ID: HY-P3260. |  |
| 7-methylguanosine nucleotidase | The enzyme also has low activity with N7-methyl-GDP, producing N7-methyl-GMP. Does not accept AMP or GMP, and has low activity with UMP. Group: Enzymes. Synonyms: cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5'-phosphatase. Enzyme Commission Number: EC 3.1.3.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3698; 7-methylguanosine nucleotidase; EC 3.1.3.91; cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5'-phosphatase. Cat No: EXWM-3698. | |
| Cytosolic 5'-nucleotidase II from Huamn, Recombinant | E.coli. Applications: Human cytosolic imp/gmp specific 5'-nucleotidase/phosphotransferase ii (cn-II) is a pure and active protein of 65kda cloned by rt-pcr amplification of mrna extracted from human hepatoma cells and expressed in e.coli. the sequence of the cloned nt5c2 gene (genbank accession number p49902) was confirmed by dna sequencing (100% identity). Group: Enzymes. Synonyms: uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.. Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. AMPase. Mole weight: 65kDa. Activity: ≥ 0.150 unit/mg protein. Storage: -20 °C in a solution containing 50 mM Tris-HCl, pH 7.6, 2 mM β-mercaptoethanol, 50% glycerol. Source: Human. Species: cN-II. uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5; CD73; NT5E; ecto-5'-nucleotidase. Pack: stable lyophilized form. Cat No: NATE-1742. | |
| IMP-specific 5'-nucleotidase | The enzyme, isolated from the yeast Saccharomyces cerevisiae, is highly specific for inosine 5'-phosphate, and has no detectable activity with other purine and pyrimidine nucleotides. Requires divalent metals, such as Mg2+, Co2+ or Mn2+. Group: Enzymes. Synonyms: ISN1 (gene name). Enzyme Commission Number: EC 3.1.3.99. CAS No. 9027-73-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3706; IMP-specific 5'-nucleotidase; EC 3.1.3.99; 9027-73-0; ISN1 (gene name). Cat No: EXWM-3706. | |
| Native Crotalus atrox venom 5'-Nucleotidase | 5'-nucleotidase is an enzyme with system name 5'-ribonucleotide phosphohydrolase. This enzyme catalyses the following chemical reaction:a 5'-ribonucleotide + H2O<-> a ribonucleoside + phosphate. This enzyme has a wide specificity for 5'-nucleotides. Group: Enzymes. Synonyms: uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5. Enzyme Commission Number: EC 3.1.3.5. CAS No. 9027-73-0. AMPase. Activity: > 200 units/mg protein. Storage: -20°C. Form: Lyophilized powder balance primarily trehalose, HEPES and CaCl2. Source: Crotalus atrox. uridine 5'-nucleotidase; 5'-adenylic phosphatase; adenosine 5'-phosphatase; AMP phosphatase; adenosine monophosphatase; 5'-mononucleotidase; AMPase; UMPase; snake venom 5'-nucleotidase; thimidine monophosphate nucleotidase; 5'-AMPase; 5'-AMP nucleotidase; AMP phosphohydrolase; IMP 5'-nucleotidase; EC 3.1.3.5. Cat No: NATE-0072. | |
| 1,N6-Ethenoadenosine 5'-monophosphate sodium salt | 1,N6-Ethenoadenosine 5'-monophosphate (1,N6-ε-AMP) is a fluorescent analog of adenosine 5'-monophosphate (AMP) that is used for analyzing the activity of 5'-nucleotidase. 1,N6-ε-AMP is characterized by a long fluorescent lifetime, detectability at low concentration, a relatively long wavelength of excitation (250-300 nm), and emission at 415 nm. Synonyms: 1,N6-ε-AMP; 1,N6-Etheno-AMP; 3-(5-O-phosphono-β-D-ribofuranosyl)-3H-imidazo[2,1-i]purine disodium salt. Grades: ≥97%. CAS No. 885597-18-2. Molecular formula: C12H12N5Na2O7P. Mole weight: 415.2. |  |
| 2',3'-cyclic-nucleotide 2'-phosphodiesterase | Also hydrolyses 3'-nucleoside monophosphates and bis-4-nitrophenyl phosphate, but not 3'-deoxynucleotides. Similar reactions are carried out by EC 3.1.27.3 (ribonuclease T1) and EC 3.1.27.5 (pancreatic ribonuclease). Group: Enzymes. Synonyms: ribonucleoside 2',3'-cyclic phosphate diesterase; 2',3 -cyclic AMP phosphodiesterase; 2',3'-cyclic nucleotidase; cyclic 2',3'-nucleotide 2'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic AMP 2'-phosphohydrolase; cyclic phosphodiesterase:3'-nucleotidase; 2',3'-cyclic n. Enzyme Commission Number: EC 3.1.4.16. CAS No. 9037-18-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3715; 2',3'-cyclic-nucleotide 2'-phosphodiesterase; EC 3.1.4.16; 9037-18-7; ribonucleoside 2',3'-cyclic phosphate diesterase; 2',3 -cyclic AMP phosphodiesterase; 2',3'-cyclic nucleotidase; cyclic 2',3'-nucleotide 2'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic AMP 2'-phosphohydrolase; cyclic phosphodiesterase:3'-nucleotidase; 2',3'-cyclic nucleotide phosphohydrolase; 2':3'-cyclic phosphodiesterase; 2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase. Cat No: EXWM-3715. | |
| ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid | ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid acts as a modulating agent for 5'-nucleotidase and may be applied to chemotherapeutic and anti-inflammatory treatments. CAS No. 2105903-93-1. Molecular formula: C16H23ClFN5O8P2. Mole weight: 529.78. | |
| ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid | ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid acts as a modulating agent for 5'-nucleotidase and may be applied to chemotherapeutic and anti-inflammatory treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 2105903-93-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C16H23ClFN5O8P2, Molecular Weight: 529.78. US Biological Life Sciences. |  Worldwide |
| ( ( ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphoryl) bis (oxy) ) bis (methylene) diisopropyl Dicarbonate | ( ( ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphoryl) bis (oxy) ) bis (methylene) diisopropyl Dicarbonate may act as a modulating agent for 5'-nucleotidase and may be applied to chemotherapeutic and anti-inflammatory treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 2105904-27-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H39ClFN5O14P2, Molecular Weight: 762.01. US Biological Life Sciences. | Worldwide |
| 3',5'-nucleoside bisphosphate phosphatase | The enzyme, characterized from the bacterium Chromobacterium violaceum, has similar catalytic efficiencies with all the bases. The enzyme has similar activity with ribonucleoside and 2'-deoxyribonucleoside 3',5'-bisphosphates, but shows no activity with nucleoside 2',5'-bisphosphates (cf. EC 3.1.3.7, 3'(2'),5'-bisphosphate nucleotidase). Group: Enzymes. Enzyme Commission Number: EC 3.1.3.97. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3704; 3',5'-nucleoside bisphosphate phosphatase; EC 3.1.3.97. Cat No: EXWM-3704. | |
| 7-Methylguanosine | 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8?±?7.5?μM. Group: Inhibitors. Alternative Names: 2-Amino-6,9-dihydro-7-methyl-6-oxo-9-1H-purinium. CAS No. 20244-86-4. Molecular formula: C11H15N5O5. Mole weight: 297.27. Appearance: Solid. Purity: 98%+. IUPACName: 2-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-1H-purin-9-ium-6-one. Canonical SMILES: CN1C=[N+] (C2=C1C (=O)NC (=N2)N)C3C (C (C (O3)CO)O)O. Catalog: ACM20244864. |  |
| Adenosine 5'-(α,β-methylene)diphosphate sodium salt | Adenosine 5'-(α,β-methylene)diphosphate sodium salt is the sodium salt of adenosine 5'-(α,β-methylene)diphosphate, which is used in the synthetic preparation of 5'-O-tosyl nucleoside. It is an ecto-5'-nucleotidase/CD73 inhibitor. It blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. It reverses the doxorubicin-resistance in ecto-5'-nucleotidase-positive MDR cells and inhibits rhodamine efflux from them. It is used as a vasoconstrictor. Synonyms: AMPCP; APCP; α,β-Methyleneadenosine 5'-diphosphate monosodium salt. Grades: ≥98% by HPLC. CAS No. 89016-30-8. Molecular formula: C11H16N5NaO9P2. Mole weight: 447.21. | |
| Adenosine 5'-monophosphate Disodium salt | Adenosine 5'-monophosphate (AMP) is used in the determination of creatine kinase and 5'-nucleotidase. Group: Coenzymes. Synonyms: Adenosine 5'-monophosphate; AMP; Adenosine 5'-monophosphate Disodium salt; AMP Disodium salt; AMP-Na2. Mole weight: 391.19. Storage: Store at -20° C. Form: Crystalline powder. Adenosine 5'-monophosphate; AMP; Adenosine 5'-monophosphate Disodium salt; AMP Disodium salt; AMP-Na2. Cat No: COEC-121. | |
| Adenosine (9- β-D-ribofuranosyladenine, Adenine riboside, Adenine-9- β-D-ribofuranoside) | In the extracellular space, ecto-5?-nucleotidase (CD73) dephosphorylates adenosine triphosphate (ATP) to produce adenosine. Adenosine has four receptors namely A1R, A2AR A2BR and A3R. Adenosine plays a key role in the osteogenic differentiation. A1R induces osteoclast differentiation and A2AR induces osteoblast differentiation. Adenosine has been used: as a supplement in embryonic type culture medium for in vitro osteogenic differentiation for evaluation of its effect on cell survival by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT assay) and cell proliferation by 3H-thymidine incorporation assay in multi drug resistant glioblastoma stem-like cells (GSCs), and as a standard in high performance liquid chromatography (HPLC). as a constituent in collagenase solution for the collagenase digestion of mice fat tissue. Group: Biochemicals. Alternative Names: 9- β-D-Ribofuranosyl-9H-purin-6-amine; 9- β-D-Ribofuranosyladenine; Adenine Riboside; Adenocard; Adenocor; Adenogesic; Adenoscan; Adrekar; Boniton; D-Adenosine; 1-(6-Amino-9H-purin-9-yl)-1-deoxy- β-D-ribofuranose; Myocol; NSC 7652. Grades: Molecular Biology Grade. CAS No. 58-61-7. Pack Sizes: 100g, 500g. Molecular Formula: C10H13N5O4, Molecular Weight: 267.25. US Biological Life Sciences. | Worldwide |
| Gemcitabine Hydrochloride (2-Deoxy-2,2-difluorocytidine Hydrochloride, dFdC, dFdCyd) | Gemcitabine is a nucleoside analog of deoxycytidine used as chemotherapy to treat patients with various types of cancer. After passage through the cell membrane via nucleoside transporters, gemcitabine undergoes complex intracellular conversion to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). dFdCTP inhibits DNA polymerase by competing with deoxycytidine triphosphate (dCTP). dFdCDP inhibits ribonucleoside reductase and DNA synthesis by causing depletion of deoxyribonucleotide pools, and thus potentiating the effects of dFdCTP. Gemcitabine can be inactivated to 2,2'-difluorodeoxyuridine, mainly by deoxycytidine deaminase. Also, 5'-nucleotidase catalyses the conversion of nucleotides to nucleosides and inhibits nucleoside kinases. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine Hydrochloride, dFdC, dFdCyd. Grades: Highly Purified. CAS No. 122111-03-9. Pack Sizes: 100mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| N-[(4-Aminophenyl)methyl]adenosine | N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor with Ki value of 29 nM for Rat ecto-5'-Nucleotidase. Synonyms: 4-Abza; 4Abza; 4 Abza; 4-ABzA; 4ABzA; 4 ABzA; N(6)-(4-aminobenzyl)adenosine; N6-[(P-Aminobenzyl)adenosine. Grades: >98 %. CAS No. 95523-13-0. Molecular formula: C17H20N6O4. Mole weight: 372.37. | |
| Native Human Prostatic Acid Phosphatase | Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of acid phosphatase are found in metastasized prostate cancer. Diseases of the bone, such as Paget's disease or hyperparathyroidism, diseases of blood cells, such as sickle-cell disease or multiple myeloma or lysosomal storage diseases, such as Gaucher's disease, will show moderately increased levels. Group: Enzymes. Synonyms: Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39. Enzyme Commission Number: EC 3.1.3.2. CAS No. 9001-77-8. Purity: Partially Purified. Apase. Mole weight: 100 kDa. Activity: > 200 U/mL (Dimension Clinical Chemistry System). Appearance: Cloudy, straw colored liquid. Storage: -20°C. Form: Liquid. Source: Human Semen. Species: Human. Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39. Cat No: NATE-0505. | |
| Native Microbial Xanthine Oxidase | Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species. Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c. Allopurinol is a synthetic drug show to inhibit xanthine oxidase. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5?-nucleotidase and adenosine deaminase when coupled with purine-nucleoside phosphorylase and uricase. Group: Enzymes. Synonyms: Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. XAO. Mole weight: mol wt ~160 kDa. Activity: > 7 units/mg solid. Storage: -20°C. Form: Lyophilized powder containing BSA and sodium glutamate as stabilizers. Source: Microbial. Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase. Cat No: NATE-0733. | |
| Native Microorganism Purine-nucleoside phosphorylase | In enzymology, a purine-nucleoside phosphorylase (EC 2.4.2.1) is an enzyme that catalyzes the chemical reaction: purine nucleoside + phosphate <-> purine + alpha-D-ribose 1-phosphate. Thus, the two substrates of this enzyme are purine nucleoside and phosphate, whereas its two products are purine and alpha-D-ribose 1-phosphate. This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5'-nucleotidase and adenosine deaminase when coupled with xanthine oxidase and uricase. Group: Enzymes. Synonyms: EC 2.4.2.1; inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynuc. Enzyme Commission Number: EC 2.4.2.1. CAS No. 9030-21-1. PNPase. Mole weight: approx. 120 kDa. Activity: Grade? 15U/mg-solid or more. Stability: Stable at-20°C for at least 12 months. Appearance: White amorphous powder, lyophilized. Source: Microorganism. EC 2.4.2.1; inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynucleoside phosphorylase; purine deoxyribonucleoside phosphorylase; purine nucleoside phosphorylase; purine ribonucleoside phosphorylase; purine-nucleoside: phosphate ribosyltransferase. Cat No: DIA-216. | |
| Native Microorganism Xanthine oxidase | Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid. These enzymes play an important role in the catabolism of purines in some species, including humans. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5'-nucleotidase and adenosine deaminase when coupled with purine-nucleoside phosphorylase and uricase. Group: Enzymes. Synonyms: EC 1.1.3.22; Xanthine oxidase; XO; XAO. Enzyme Commission Number: EC 1.1.3.22. CAS No. 9054-84-6. XAO. Mole weight: approx. 160 kDa. Activity: Grade? 10U/mg-solid or more. Stability: Stable at-20°C for at least year. Appearance: Reddish brown amorphous powder, lyophilized. Source: Microorganism. EC 1.1.3.22; Xanthine oxidase; XO; XAO. Cat No: DIA-218. | |
| P1,P5-Di(adenosine-5')pentaphosphate trilithium salt | A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5?-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor. Group: Biochemicals. Alternative Names: P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, 94108-02-8, A(5)P5(5)A, AC1O4WDE, D6392_SIGMA, CTK8G2238, EINECS 302-339-2, AP5A lithium salt P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, AG-H-86941, Diadenosine pentaphosphate trilithium salt, Diadenosine pentaphosphate pentalithium salt, K00187, A(5 inverted exclamation marka)P5(5 inverted exclamation marka)A trilithium sal. Grades: Highly Purified. CAS No. 75522-97-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H26N10O22P5Li3, Molecular Weight: 934.17. US Biological Life Sciences. | Worldwide |
| Prostatic acid phosphatase from Human, recombinant | ACPP, also known as prostatic acid phosphatase isoform PAP, is a type I integral membrane protein of the plasma membrane and lysosomes, and a secreted form also exists. The concentration of ACPP is elevated in the circulation of prostate cancer patients, making the enzyme a marker for the progression of prostate cancer. Recombinant human ACPP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. Group: Enzymes. Synonyms: Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39; ACPP; ACP-3, ACP3. Enzyme Commission Number: EC 3.1.3.2. CAS No. 9001-77-8. Purity: > 95% by SDS-PAGE. Apase. Mole weight: 41.8 kDa. Activity: >100,000 units/mg. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: Baculovirus. Species: Human. Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39; ACPP; ACP-3, ACP3. Cat No: NATE-1673. | |
| PSB 12379 | PSB 12379, an α,β-Methylene-ADP (AOPCP) derivative, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human). PSB-12379 displayed high selectivity versus other ecto-nucleotidases (NTPDase 1-3 and NPP 1-3) and ADP-activated P2Y (P2Y1 and P2Y12) receptors. PBS-12379 represents the most potent eN inhibitor known to date, showing high selectivity and metabolic stability. Synonyms: PSB12379; PSB-12379; N6-Benzyl-α,β-methyleneadenosine 5'-diphosphate; N6-benzyl-(alpha,beta)-methylene-ADP; (1-Deoxy-1-(6-benzylamino-9H-purine-9-yl)-beta-D-ribofuranose-5-O-yl)phosphonylmethylphosphonic acid; N-Benzyl-5'-O-[hydroxy (phosphonomethyl) phosphoryl]adenosine; N-(phenylmethyl)-adenosine, 5'-[hydrogen P-(phosphonomethyl)phosphonate]. Grades: ≥98% by HPLC. CAS No. 1802226-78-3. Molecular formula: C18H23N5O9P2. Mole weight: 515.35. | |
| Succinyladenosine | Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency [1]. Uses: Scientific research. Group: Natural products. Alternative Names: N6-Succinyl adenosine. CAS No. 4542-23-8. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-113284. | |
| thymidylate 5'-phosphatase | Acts on 5-methyl-dCMP and on TMP, but more slowly than on dTMP. Group: Enzymes. Synonyms: thymidylate 5'-nucleotidase; deoxythymidylate 5'-nucleotidase; thymidylate nucleotidase; deoxythymidylic 5'-nucleotidase; deoxythymidylate phosphohydrolase; dTMPase. Enzyme Commission Number: EC 3.1.3.35. CAS No. 9026-80-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3638; thymidylate 5'-phosphatase; EC 3.1.3.35; 9026-80-6; thymidylate 5'-nucleotidase; deoxythymidylate 5'-nucleotidase; thymidylate nucleotidase; deoxythymidylic 5'-nucleotidase; deoxythymidylate phosphohydrolase; dTMPase. Cat No: EXWM-3638. | |
| UDP-sugar diphosphatase | A divalent cation is required for activity. UDP-sugar is the best substrate, although other nucleoside-sugar diphosphates are used as substrates with similar Km values but much lower maximum velocities. Thus, this enzyme has a specificity distinct from that of ADP-sugar diphosphatase (EC 3.6.1.21). Some but not all enzymes of this class also appear to have 5'-nucleotidase (see EC 3.1.3.5) activity. Group: Enzymes. Synonyms: nucleosidediphosphate-sugar pyrophosphatase; nucleosidediphosphate-sugar diphosphatase; UDP-sugar hydrolase; UDP-sugar pyrophosphatase. Enzyme Commission Number: EC 3.6.1.45. CAS No. 55354-38-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4622; UDP-sugar diphosphatase; EC 3.6.1.45; 55354-38-6; nucleosidediphosphate-sugar pyrophosphatase; nucleosidediphosphate-sugar diphosphatase; UDP-sugar hydrolase; UDP-sugar pyrophosphatase. Cat No: EXWM-4622. | |
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