Nucleotidase Suppliers USA
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Product | Description | |
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1,N6-Ethenoadenosine 5'-monophosphate sodium salt Quick inquiry Where to buy Suppliers range | 1,N6-Ethenoadenosine 5'-monophosphate (1,N6-ε-AMP) is a fluorescent analog of adenosine 5'-monophosphate (AMP) that is used for analyzing the activity of 5'-nucleotidase. 1,N6-ε-AMP is characterized by a long fluorescent lifetime, detectability at low concentration, a relatively long wavelength of excitation (250-300 nm), and emission at 415 nm. Synonyms: 1,N6-ε-AMP; 1,N6-Etheno-AMP; 3-(5-O-phosphono-β-D-ribofuranosyl)-3H-imidazo[2,1-i]purine disodium salt. Grades: ≥97%. CAS No. 885597-18-2. Molecular formula: C12H12N5Na2O7P. Mole weight: 415.2. | |
( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid Quick inquiry Where to buy Suppliers range | ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid acts as a modulating agent for 5'-nucleotidase and may be applied to chemotherapeutic and anti-inflammatory treatments. CAS No. 2105903-93-1. Molecular formula: C16H23ClFN5O8P2. Mole weight: 529.78. | |
( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid Quick inquiry Where to buy Suppliers range | ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphonic Acid acts as a modulating agent for 5'-nucleotidase and may be applied to chemotherapeutic and anti-inflammatory treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 2105903-93-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C16H23ClFN5O8P2, Molecular Weight: 529.78. US Biological Life Sciences. | Worldwide |
( ( ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphoryl) bis (oxy) ) bis (methylene) diisopropyl Dicarbonate Quick inquiry Where to buy Suppliers range | ( ( ( ( ( ( (2R, 3R, 4S, 5R) -5- (2-Chloro-6- (cyclopentylamino) -9H-purin-9-yl) -4-fluoro-3-hydroxytetrahydrofuran-2-yl) methoxy) (hydroxy) phosphoryl) methyl) phosphoryl) bis (oxy) ) bis (methylene) diisopropyl Dicarbonate may act as a modulating agent for 5'-nucleotidase and may be applied to chemotherapeutic and anti-inflammatory treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 2105904-27-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H39ClFN5O14P2, Molecular Weight: 762.01. US Biological Life Sciences. | Worldwide |
Adenosine 5'-(α,β-methylene)diphosphate sodium salt Quick inquiry Where to buy Suppliers range | Adenosine 5'-(α,β-methylene)diphosphate sodium salt is the sodium salt of adenosine 5'-(α,β-methylene)diphosphate, which is used in the synthetic preparation of 5'-O-tosyl nucleoside. It is an ecto-5'-nucleotidase/CD73 inhibitor. It blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. It reverses the doxorubicin-resistance in ecto-5'-nucleotidase-positive MDR cells and inhibits rhodamine efflux from them. It is used as a vasoconstrictor. Synonyms: AMPCP; APCP; α,β-Methyleneadenosine 5'-diphosphate monosodium salt. Grades: ≥98% by HPLC. CAS No. 89016-30-8. Molecular formula: C11H16N5NaO9P2. Mole weight: 447.21. | |
Adenosine (9- β-D-ribofuranosyladenine, Adenine riboside, Adenine-9- β-D-ribofuranoside) Quick inquiry Where to buy Suppliers range | In the extracellular space, ecto-5?-nucleotidase (CD73) dephosphorylates adenosine triphosphate (ATP) to produce adenosine. Adenosine has four receptors namely A1R, A2AR A2BR and A3R. Adenosine plays a key role in the osteogenic differentiation. A1R induces osteoclast differentiation and A2AR induces osteoblast differentiation. Adenosine has been used: as a supplement in embryonic type culture medium for in vitro osteogenic differentiation for evaluation of its effect on cell survival by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT assay) and cell proliferation by 3H-thymidine incorporation assay in multi drug resistant glioblastoma stem-like cells (GSCs), and as a standard in high performance liquid chromatography (HPLC). as a constituent in collagenase solution for the collagenase digestion of mice fat tissue. Group: Biochemicals. Alternative Names: 9- β-D-Ribofuranosyl-9H-purin-6-amine; 9- β-D-Ribofuranosyladenine; Adenine Riboside; Adenocard; Adenocor; Adenogesic; Adenoscan; Adrekar; Boniton; D-Adenosine; 1-(6-Amino-9H-purin-9-yl)-1-deoxy- β-D-ribofuranose; Myocol; NSC 7652. Grades: Molecular Biology Grade. CAS No. 58-61-7. Pack Sizes: 100g, 500g. Molecular Formula: C10H13N5O4, Molecular Weight: 267.25. US Biological Life Sciences. | Worldwide |
Gemcitabine Hydrochloride (2-Deoxy-2,2-difluorocytidine Hydrochloride, dFdC, dFdCyd) Quick inquiry Where to buy Suppliers range | Gemcitabine is a nucleoside analog of deoxycytidine used as chemotherapy to treat patients with various types of cancer. After passage through the cell membrane via nucleoside transporters, gemcitabine undergoes complex intracellular conversion to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). dFdCTP inhibits DNA polymerase by competing with deoxycytidine triphosphate (dCTP). dFdCDP inhibits ribonucleoside reductase and DNA synthesis by causing depletion of deoxyribonucleotide pools, and thus potentiating the effects of dFdCTP. Gemcitabine can be inactivated to 2,2'-difluorodeoxyuridine, mainly by deoxycytidine deaminase. Also, 5'-nucleotidase catalyses the conversion of nucleotides to nucleosides and inhibits nucleoside kinases. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine Hydrochloride, dFdC, dFdCyd. Grades: Highly Purified. CAS No. 122111-03-9. Pack Sizes: 100mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
N-[(4-Aminophenyl)methyl]adenosine Quick inquiry Where to buy Suppliers range | N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor with Ki value of 29 nM for Rat ecto-5'-Nucleotidase. Synonyms: 4-Abza; 4Abza; 4 Abza; 4-ABzA; 4ABzA; 4 ABzA; N(6)-(4-aminobenzyl)adenosine; N6-[(P-Aminobenzyl)adenosine. Grades: >98 %. CAS No. 95523-13-0. Molecular formula: C17H20N6O4. Mole weight: 372.37. | |
P1,P5-Di(adenosine-5')pentaphosphate trilithium salt Quick inquiry Where to buy Suppliers range | A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5?-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor. Group: Biochemicals. Alternative Names: P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, 94108-02-8, A(5)P5(5)A, AC1O4WDE, D6392_SIGMA, CTK8G2238, EINECS 302-339-2, AP5A lithium salt P1,P5-Di(adenosine-5) pentaphosphate pentalithium salt, AG-H-86941, Diadenosine pentaphosphate trilithium salt, Diadenosine pentaphosphate pentalithium salt, K00187, A(5 inverted exclamation marka)P5(5 inverted exclamation marka)A trilithium salt, Adenosine 5-(hexahydrogen pentaphosphate), 5.5-ester with adenosine, pentalithium salt, P1,P5-Di(adenosine-5 inverted exclamation marka) pentaphosphate trilithium salt, 75522-97-3, pentalithium bis[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate. Grades: Highly Purified. CAS No. 75522-97-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H26N10O22P5Li3, Molecular Weight: 934.17. US Biological Life Sciences. | Worldwide |
PSB 12379 Quick inquiry Where to buy Suppliers range | PSB 12379, an α,β-Methylene-ADP (AOPCP) derivative, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human). PSB-12379 displayed high selectivity versus other ecto-nucleotidases (NTPDase 1-3 and NPP 1-3) and ADP-activated P2Y (P2Y1 and P2Y12) receptors. PBS-12379 represents the most potent eN inhibitor known to date, showing high selectivity and metabolic stability. Synonyms: PSB12379; PSB-12379; N6-Benzyl-α,β-methyleneadenosine 5'-diphosphate; N6-benzyl-(alpha,beta)-methylene-ADP; (1-Deoxy-1-(6-benzylamino-9H-purine-9-yl)-beta-D-ribofuranose-5-O-yl)phosphonylmethylphosphonic acid; N-Benzyl-5'-O-[hydroxy (phosphonomethyl) phosphoryl]adenosine; N-(phenylmethyl)-adenosine, 5'-[hydrogen P-(phosphonomethyl)phosphonate]. Grades: ≥98% by HPLC. CAS No. 1802226-78-3. Molecular formula: C18H23N5O9P2. Mole weight: 515.35. |