Obeticholic Acid Suppliers USA
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Product | Description | |
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Obeticholic Acid Quick inquiry Where to buy Suppliers range | Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM. It reduced liver fat and reverted cholestasis in a rat model. Synonyms: 6-ECDCA; 6-Ethylchenodeoxycholic acid; Obeticholic acid; INT 747; INT-747; INT747; 6-ECDCA; Ocaliva; (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Grades: >98%. CAS No. 459789-99-2. Molecular formula: C26H44O4. Mole weight: 420.634. | |
Tauro-obeticholic acid Quick inquiry Where to buy Suppliers range | Tauro-obeticholic acid is an active metabolite of obeticholic acid, a farnesoid X receptor (FXR) agonist. Synonyms: Obeticholic acid taurine conjugate; Tauro 6-ethylchenodeoxycholic acid. Grades: ≥95%. CAS No. 863239-61-6. Molecular formula: C28H49NO6S. Mole weight: 527.76. | |
EP-024297 Quick inquiry Where to buy Suppliers range | EP-024297 is a novel agonist of farnesoid X receptor (FXR). Study in Chinese hamster ovary cells showed that it is 20000-fold more potent than obeticholic acid (OCA). EP-024297 is selective for FXR over TGR5. It promisingly becomes a new treatment of NASH. Uses: The potential treatment of nash. Synonyms: EP-024297; EP 024297; EP024297. | |
(R)-4-((3R,5R,8S,9S,10R,13R,14S,17R,Z)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid Quick inquiry Where to buy Suppliers range | (R)-4-((3R,5R,8S,9S,10R,13R,14S,17R,Z)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a] phenanthren-17-yl)pentanoic acid is an impurity of obeticholic acid, which is used in the treatment of primary biliary cholangitis and various liver diseases. Synonyms: (E)-3-hydroxy-6-ethylidene-7-keto-5-cholan-24-oic acid. CAS No. 1516887-34-5. Molecular formula: C26H40O4. Mole weight: 416.60. |