Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| ornithine decarboxylase | A pyridoxal-phosphate protein. Group: Enzymes. Synonyms: SpeC; L-ornithine carboxy-lyase. Enzyme Commission Number: EC 4.1.1.17. CAS No. 9024-60-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4761; ornithine decarboxylase; EC 4.1.1.17; 9024-60-6; SpeC; L-ornithine carboxy-lyase. Cat No: EXWM-4761. |  |
| Monoclonal Anti-Ornithine Decarboxylase (ODC) antibody produced in mouse | clone ODC-29, ascites fluid. Group: Fluorescence/luminescence spectroscopy. |  |
| 1,2-Didecanoyl-sn-glycerol | 1,2-Didecanoyl-sn-glycerol increases ornithine decarboxylase activity associated with tumor promotion in mouse skin. It can also function as a bioregulator of protein kinase C in human platelets. Group: Biochemicals. Grades: Highly Purified. CAS No. 60514-49-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C23H44O5, Molecular Weight: 400.59. US Biological Life Sciences. |  Worldwide |
| 24-Epibrassinolide | Epibrassinolide is a biologically active compound of the brassinosteroids that can be isolated from various plants. It belongs to steroid-derived plant growth regulator family and has been shown to decrease toxicity and stimulate healthy plant growth in plants under stress. It may be a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. It has also been shown to protect neuronal PC12 cells from 1-methyl-4-phenylpyridinium-induced oxidative stress and consequent apoptosis in dopaminergic neurons. It induced the decrease of intracellular polyamine levels accompanied by a significant ornithine decarboxylase (ODC) down-regulation in each prostate cancer cell. Uses: Plant growth regulators. Synonyms: B1105; BP55; (5S,6R,7aR,9aS)-10-[(2S,3R,4R,5R)-3,4-Dihydroxy-5,6-dimethylheptan-2-yl]-5,6-dihydroxy-7a,9a-dimethylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one; 6H-Benz[c]indeno[5,4-e]oxepin-6-one,1-[(1S,2R,3R,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]hexadecahydro-8,9-dihydroxy-10a,12a-dimethyl-,(1R,3aS,3bS,6aS,8S,9R,10aR,10bS,12aS)-; (22R,23R,24R)-2a,3a,22,23-Tetrahydroxy-B-homo-7-oxa-5a-ergostan-6-one; 24(R)-Epibrassinolide; 24-epi-Brassinolide. Grade: 95%. CAS No. 78821-43-9. Molecular formula: C28H48O6. Mole weight: 480.68. |  |
| (2S)-(+)-Amino-6-iodoacetamidohexanoic Acid | (2S)-(+)-Amino-6-iodoacetamidohexanoic acid is an ornithine decarboxylase and arginase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 35748-65-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C7H13IN2O3, Molecular Weight: 300.089999999999. US Biological Life Sciences. | Worldwide |
| 4-Deoxypyridoxine 5'-phosphate | 4-Deoxypyridoxine 5'-phosphate, a pyridoxal 5'-phosphate analogue, is a sphingosine 1-phosphate (S1P) inhibitor that inhibits ornithine decarboxylase activity with a Ki of 60 μM. It is a competitive inhibitor of the activation of glutamate apodecarboxylase by pyridoxal 5'-phosphate (Ki = 0.27 μM) and strongly inhibits glutamate-dependent labeling of glutamate decarboxylase. Synonyms: 5-hydroxy-4,6-dimethyl-3-pyridinemethanol, 3-(dihydrogen phosphate); NSC 29870; 5-(Phosphonooxymethyl)-2,4-dimethyl-3-pyridinol; (5-hydroxy-4,6-dimethyl-3-pyridinyl)methyl dihydrogen phosphate; 3-Pyridinemethanol, 5-hydroxy-4,6-dimethyl-, α-(dihydrogen phosphate); Deoxypyridoxine-P. Grade: ≥98%. CAS No. 883-84-1. Molecular formula: C8H12NO5P. Mole weight: 233.16. | |
| Caffeic Acid, Dimethyl Ether, Phenethyl Ester (Phenethyl Dimethyl Caffeate) | An Inhibitor of ornithine decarboxylase and protein tyrosine kinase. Group: Biochemicals. Alternative Names: Phenethyl Dimethyl Caffeate. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Chlorphenamine EP Impurity C | An impurity of Chlorpheniramine, which inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxylase mRNA translation by 50%-70% at the 250 μM. Synonyms: N-Desmethylchlorpheniramine; monodesmethylchlorpheniramine; N-Methyl-3-(4-chlorophenyl)-3-(2-pyridyl)propan-1-amine; γ-(4-Chlorophenyl)-N-methyl-2-pyridinepropanamine. Grade: 95%. CAS No. 20619-12-9. Molecular formula: C15H17ClN2. Mole weight: 260.76. | |
| Chlorpheniramine N-Oxide | Chlorpheniramine N-Oxide is the major metabolite of Chlorpheniramine. Chlorpheniramine inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxylase mRNA translation by 50%-70% at the 250 μM. Synonyms: 2-Pyridinepropanamine,γ-(4-chlorophenyl)-N,N-dimethyl-N-Oxide. Grade: > 95%. CAS No. 120244-82-8. Molecular formula: C16H19ClN2O. Mole weight: 290.79. | |
| diaminobutyrate decarboxylase | A pyridoxal-phosphate protein that requires a divalent cation for activity. N4-Acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine and lysine are not substrates. Found in the proteobacteria Haemophilus influenzae and Acinetobacter baumannii. In the latter, this enzyme is cotranscribed with the dat gene that encodes EC 2.6.1.76, diaminobutyrate-2-oxoglutarate transaminase, which can supply the substrate for this enzyme. Group: Enzymes. Synonyms: DABA DC; L-2,4-diaminobutyrate decarboxylase; L-2,4-diaminobutanoate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4835; diaminobutyrate decarboxylase; EC 4.1.1.86; DABA DC; L-2,4-diaminobutyrate decarboxylase; L-2,4-diaminobutanoate carboxy-lyase. Cat No: EXWM-4835. | |
| Diethylnorspermine | diethylnorspermine, also known as DENSPM, is a potent inducer of spermidine/spermine N1-acetyltransferase, is able to increase enzyme activity 200-1000 fold. The cell death induced by DENSPM treatment was apoptotic, as evidenced by cleavage of procaspase 3 and induction of caspase-3 activity. The DENSPM-induced polyamine depletion was also caused by the inhibition of ornithine decarboxylase. LA-N-1 cells contained a higher level of the prosurvival protein survivin, which was further increased after DENSPM treatment. Synonyms: DE-333, DE 333; DE333; BE-333, BE 333; BE333; N1,N11-Diethylnorspermine; 1,11-bis(ethylamino)-4,8-diazaundecan. CAS No. 121749-39-1. Molecular formula: C13H36Cl4N4. Mole weight: 244.42. | |
| Eflornithine | Eflornithine is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells. Synonyms: Ornithine, 2-(difluoromethyl)-; 2-(Difluoromethyl)ornithine; 2-(Difluoromethyl)-DL-ornithine; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; DFMO; DFMO (growth regulator); Difluromethylornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric acid; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine. Grade: ≥95%. CAS No. 70052-12-9. Molecular formula: C6H12F2N2O2. Mole weight: 182.17. | |
| Eflornithine | Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DFMO; MDL71782; RMI71782; α-difluoromethylornithine. CAS No. 70052-12-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0744. |  |
| Eflornithine hydrochloride | Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. Synonyms: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; MDL 71782 hydrochloride; RMI 71782 hydrochloride; MDL-71782 hydrochloride; RMI-71782 hydrochloride; α-difluoromethylornithine hydrochloride; Vaniqa hydrochloride. Grade: >98%. CAS No. 68278-23-9. Molecular formula: C6H13ClF2N2O2. Mole weight: 218.63. | |
| Eflornithine hydrochloride | Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride. CAS No. 68278-23-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0744A. | |
| Eflornithine hydrochloride hydrate | Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate. CAS No. 96020-91-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0744B. | |
| Eflornithine hydrochloride, hydrate | Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. It is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. It displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways. It also demonstrates antiparasitic activity in a model of C. parvum infection. Synonyms: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; MDL 71782 hydrochloride hydrate; RMI 71782 hydrochloride hydrate; MDL71782 hydrochloride hydrate; RMI71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate; Vaniqa hydrochloride hydrate. Grade: 98%. CAS No. 96020-91-6. Molecular formula: C6H15ClF2N2O3. Mole weight: 236.64. | |
| Eflornithine Hydrochloride Monoydrate | Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism. Group: Biochemicals. Alternative Names: 2-(Difluoromethyl)-DL-ornithine Hydrochloride Hydrate; 2- (Difluoromethyl) ornithine; DFMO; DL-2- (Difluoromethyl) ornithine; DL-α - (Difluoromethyl) ornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α , δ -Diamino-α - (difluoromethyl) valeric Acid; α-(Difluoromethyl)-DL-ornithine; α - (Difluoromethyl) ornithine. Grades: Highly Purified. CAS No. 96020-91-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??ClF?N?O?, Molecular Weight: 236.64. US Biological Life Sciences. | Worldwide |
| Herbacetin | Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects[1]. Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis[2]. Uses: Scientific research. Group: Natural products. CAS No. 527-95-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0240. | |
| Ivospemin | Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SBP-101. CAS No. 748119-79-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132822. | |
| L-Asparagine Monohydrate | L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine. L-Asparagine, a proteinogenic amino acid, from non-animal source is used in biomanufacturing cell culture systems for the production of therapeutic recombinant proteins and monoclonal antibodies. It has also been used as a component of LHC basal media for the culture of human airway epithelial cells.The amino acid L-asparagine is a structural analog of L-aspartic acid, where the side chain of the carboxylic acid moiety is amidated to give a terminal amine group. This renders L-asparagine neutral at physiological pH. The amide group of asparagine is derived from glutamine, in the reaction of aspartate and glutamine in the presence of ATP to yield asparagine and glutamate. In vivo, asparagine is hydrolyzed to aspartate and NH4+ by asparaginase. Asparagine is also an important amino acid in glycopeptide bonds, via N-glycosyl linkages to the sugar rings. Group: Biochemicals. Alternative Names: (S)-2-Aminosuccinic acid 4-amide; (S)-(+)-2-Aminosuccinamic acid; L-Aspartic acid 4-amide; L-Asn-OH·H2O. Grades: Cell Culture Grade. CAS No. 5794-13-8. Pack Sizes: 100g, 500g, 1Kg, 2.5Kg. Molecular Formula: C4H8N2O3 H2O, Molecular Weight: 150.13. US Biological Life Sciences. | Worldwide |
| Native Porcine Diamine Oxidase | Diamine oxidase from porcine kidney is a homodimer consisting of 2 equal subunits with a molecular weight of 87 kDa each. Each subunit contains one molecule of pyridoxal phosphate and one atom of copper. The molecular mass of the enzyme is found to be 170 kDa. The enzyme is a glycoprotein containing 5% hexose, 3.3% glucosamine, 2.6% N-acetylglucosamine, and 0.25% N-acetylneuraminic acid. The enzyme exhibits a high affinity for concanavalin A. It catalyzes the oxidation of monoamines, diamines, and histamine to aldehydes, ammonia, and hydrogen peroxide. Optimum pH with cadverine and histamine as substrates is found to be 6.3-7.4.2 The enzyme is classified as a copper amine oxid...a luminescence-based test for determining ornithine decarboxylase activity. diamine oxidase from porcine kidney has also been used in a study to investigate n-linked oligosaccharide structures in diamine oxidase. Group: Enzymes. Synonyms: EC 1.4.3.6; 9001-53-0; Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing); Diamine Oxidase; Amine oxidase (copper-containing). Enzyme Commission Number: EC 1.4.3.6. CAS No. 9001-53-0. Diamine Oxidase. Activity: > 0.05 unit/mg solid. Storage: -20°C. Source: Porcine kidney. Species: Porcine. EC 1.4.3.6; 9001-53-0; Amine:oxygen oxidoreductase (deaminating) (pyridoxal-containing); Diamine Oxidase; Amine oxidase (copper-containing). | |
| NCAO | N-ω-chloroacetyl-L-ornithine (NCAO) is a potent reversible competitive ornithine decarboxylase ( ODC ) inhibitor that exerts cytotoxic and antiproliferative effects on tumor cell lines with EC 50 values ranging from 1 to 50.6 μM. NCAO induces tumor cell Apoptosis and inhibits tumor cell migration in vitro. NCAO also exhibits a potent antitumor activity against both solid and ascitic tumors in a mouse model using the myeloma (Ag8) cell line. NCAO is promising for research of antitumor agents [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 20584-81-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-160843. | |
| NMDA Antagonist XI, N1-dansyl-spermine (NMDA Channel Blocker, N1-dansyl-spermine, N1-DnsSpm) | An N-sulfonyl-polyamine that acts as a potent and more specific antagonist ofnMDA receptors expressed in Xenopus oocytes (IC50 = 310, 340nM in NR1/NR2A and NR1/NR2B, respectively). The inhibition appears to be voltage-dependent and is non-competitive with respect to glutamate and glycine. Exhibits about 50-fold greater selectivity over NR1/NR2C and NR1/NR2D receptors (IC50 = 16 and 13uM, respectively). Also shown to block c-AMP-dependent, calmodulin-activated phosphodiesterase (IC50 = 58uM) and diminishes the induction of ornithine decarboxylase. At higher concentration (100uM) it is shown to reduce spontaneous epileptiform activity in mouse cortical slices. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Staurosporin | Staurosporine is an alkaloid isolated from the culture broth of Streptomyces staurospores and is a super-potent, cell permeable PKC inhibitor (IC50=0.7); at higher concentrations Staurosporine inhibits other protein kinases: CDK2/cyclin A (IC50=7uM) and CDK4/cyclin D (IC50=3-10uM). At a concentration of 50-100nM it is a functional neurotrophins agonist promoting neurite outgrowth in neuroblastoma, pheochromocytoma and brain primary neuronal cultures. Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase. This compound displays selectivity toward the PKC isoforms, inhibiting PKCα, PKC β, PKCγ, PKCδ, and PKCε, but not PKC?, and induces PKC translocation. Staurosporine also inhibits topoisomerase II directly by interaction with the ATP binding site, augments PMA-induced ornithine decarboxylase, and activates a bcl-2-regulated apoptosis pathway. Source:Streptomyces staurosporeus. Group: Biochemicals. Alternative Names: Antibiotic AM2282; Antibiotic 230; CCRIS 3272. Grades: Highly Purified. CAS No. 62996-74-1. Pack Sizes: 100ug, 1mg, 5mg, 10mg. Molecular Formula: C28H26N4O3, Molecular Weight: 466.53. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
