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| Product | Description | |
|---|---|---|
| Oxaliplatin | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C8H14N2O4Pt C8H14N2O4Pt. CAS No. 61825-94-3. Prepack ID 27659030-1g. Molecular Weight 397.29. See USA prepack pricing. |  |
| Oxaliplatin | 250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C8H14N2O4Pt C8H14N2O4Pt. CAS No. 61825-94-3. Prepack ID 27659030-250mg. Molecular Weight 397.29. See USA prepack pricing. | |
| Oxaliplatin | Oxaliplatin is a a third-generation, diaminocyclohexane-containing platinum anti-cancer drug. It is typically used in combination with fluorouracil (5-FU) and leucovorin, known as FOLFOX, for the treatment of colorectal cancer. The leucovorin-modulated single-agent 5-FU regimens achieved a median overall survival of 15 months or less. Combination regimens of FOLFOX consistently lead to median survivals in the 15-20 month range. Group: Biochemicals. Alternative Names: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']platinum; (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN'][ethanedioato(2-)-kO1,kO2]platinum; (1R-trans)-1,2-Cyclohexanediamine Platinum Complex; Dacplat; Eloxatin; Elplat; Lipoxal; Oxalatoplatinum. Grades: Highly Purified. CAS No. 61825-94-363121-00-6. Pack Sizes: 25mg, 50mg, 100mg, 300mg, 500mg. Molecular Formula: C8H14N2O4Pt, Molecular Weight: 397.29. US Biological Life Sciences. |  Worldwide |
| Oxaliplatin | Oxaliplatin is a DNA synthesis inhibitor. Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. Oxaliplatin can be used for cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61825-94-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-17371. |  |
| Oxaliplatin | Oxaliplatin is a platinum-based antineoplastic agent used in cancer chemotherapy that inhibits DNA synthesis by conforming DNA adducts in cancer cells. Synonyms: Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]-, (SP-4-2)-; (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]platinum; 1,2-Cyclohexanediamine, platinum complex, (1R-trans)-; Platinum, (1,2-cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']-, [SP-4-2-(1R-trans)]-; Platinum, [(1R,2R)-1,2-cyclohexanediamine-κN,κN'][ethanedioato(2-)-κO1,κO2]-, (SP-4-2)-; Dacplat; Eloxatin; Elplat; l-OHP; Lipoxal; NSC 266046; Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II); Oxalato[trans-(-)-1,2-cyclohexanediamine]platinum(II); Oxalatoplatin; Oxalatoplatinum; Platinum, (1,2-cyclohexanediamine-κN,κN')[ethanedioato(2-)-κO1,κO2]-, [SP-4-2-(1R-trans)]-; RP 54780; trans-L-Diaminocyclohexane oxalatoplatinum. Grades: >98%. CAS No. 61825-94-3. Molecular formula: C8H14N2O4Pt. Mole weight: 397.29. |  |
| Oxaliplatin | Oxaliplatin, marketed as Eloxatin by Sanofi, is a platinum-based antineoplastic agent used in cancer chemotherapy.It is on the World Health Organizations List of Essential Medicines, a list of the most important medications needed in a basic health system. Group: Inhibitors. Alternative Names: Dacplat;Oxaliplatin;Elocatin. CAS No. 61825-94-3. Molecular formula: C8H14N2O4Pt. Mole weight: 395.27. Appearance: Solid. Purity: ≥98.0%. Canonical SMILES: O=C (O1) C (O [Pt]21 [NH2] [C@@H]3CCCC [C@H]3 [NH2]2) =O. Catalog: ACM61825943. |  |
| Oxaliplatin EP Impurity 1 | Oxaliplatin EP Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 82398-34-3. Molecular Formula: C12H24N5O5Pt2+. Mole Weight: 708.52. Catalog: APB82398343. |  |
| Oxaliplatin EP Impurity B | Oxaliplatin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 89955-85-1. Molecular Formula: C6H14N2O2Pt2+. Mole Weight: 341.27. Catalog: APB89955851. | |
| Oxaliplatin EP Impurity C | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: (OC-6-33)-[(1R,2R)-cyclohexane-1,2-diamine-kN,kN'][ethanedioato(2-)-κN,κN]dihydroxyplatinum. Grades: > 95%. Molecular formula: C8H14N2O6Pt. Mole weight: 429.3. | |
| Oxaliplatin EP Impurity D | Oxaliplatin EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 61758-77-8. Molecular Formula: C8H12N2O4Pt. Mole Weight: 395.28. Catalog: APB61758778. | |
| Oxaliplatin EP Impurity D | The (S,S) Oxaliplatin isomer. Synonyms: (S,S)-Oxaliplatin; [SP-4-2-(1S-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']platinum. Grades: > 95%. CAS No. 61758-77-8. Molecular formula: C8H14N2O4Pt. Mole weight: 397.3. | |
| Oxaliplatin EP Impurity E | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: (SP-4-2)-di-μ-oxidobis[(1R,2R)-cyclohexane-1,2-diamine-1κ2N,2κ2N']diplatinum; Diaquodiaminocyclohexaneplatinum dimer; (SP-4-2)-Di-oxobis[(1R,2R)-1,2-cyclohexanediamine-κN,κN']diplatinum(2+); Platinum(2+), bis(1,2-cyclohexanediamine-N,N')di-μ-hydroxydi-, stereoisomer; 1,2-Cyclohexanediamine, platinum complex, (1R-trans)-. Grades: ≥95%. CAS No. 108033-10-9. Molecular formula: C12H28N4O2Pt2. Mole weight: 650.54. | |
| Oxaliplatin EP Impurity E | Oxaliplatin EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H24N4O2Pt2. Mole Weight: 646.52. Catalog: APB10917. | |
| Oxaliplatin Impurity 1 | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: Dihydroxy Oxaliplatin-Pt(IV); (OC-6-33)-[(1R, 2R)-1, 2-Cyclohexanediamine-κN1, κN2][ethanedioato(2-)-κO1, κO2]dihydroxyplatinum. Grades: > 95%. CAS No. 111321-67-6. Molecular formula: C8H16N2O6Pt. Mole weight: 431.31. | |
| Oxaliplatin Impurity 2 | Cas No. 82398-34-3. | |
| Oxaliplatin Impurity 2 | Oxaliplatin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 66900-68-3. Molecular Formula: C6H12N4O6Pt. Mole Weight: 431.27. Catalog: APB66900683. | |
| Oxaliplatin Impurity B | A metabolite of Oxaliplatin, which is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Synonyms: (SP-4-2)-diaqua[(1R,2R)-cyclohexane-1,2-diamine-kN,kN']platinum. Grades: > 95%. Molecular formula: C6H18N2O2Pt. Mole weight: 345.3. | |
| Ascorbic Acid EP Impurity E (Oxaliplatin EP Impurity A) | Ascorbic Acid EP Impurity E (Oxaliplatin EP Impurity A). Uses: For analytical and research use. Group: Impurity standards. CAS No. 144-62-7. Molecular Formula: C2H2O4. Mole Weight: 90.03. Catalog: APB144627. | |
| Dihydroxy oxaliplatin-pt(IV) | Dihydroxy oxaliplatin-pt(IV). Group: Biochemicals. Alternative Names: (OC-6-33)-[(1R, 2R)-1, 2-cyclohexanediamine-κ N1, κ N2][ethanedioato(2-)-κ O1, κ O2]dihydroxyplatinum; [OC-6-33-(1R-trans)]-(1, 2-cyclohexanediamine-N, N')[ethanedioato(2-)-O, O']dihydroxyplatinum; (1R-trans)-1,2-Cyclohexanediamine platinum complex. Grades: Highly Purified. CAS No. 111321-67-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C8H16N2O6Pt. US Biological Life Sciences. | Worldwide |
| Dihydroxy Oxaliplatin-Pt(IV) | Dihydroxy Oxaliplatin-Pt(IV). Uses: For analytical and research use. Group: Impurity standards. CAS No. 111321-67-6. Molecular Formula: C8H16N2O6Pt. Mole Weight: 431.30. Catalog: APS111321676. SMILES: O[Pt+2]12 (O) ([NH2][C@@H]3CCCC[C@H]3[NH2]1)[O-]C (=O)C (=O)[O-]2. Format: Neat. | |
| (S,S)-Oxaliplatin | (S,S)-Oxaliplatin. Group: Biochemicals. Alternative Names: [SP-4-2-(1S-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']platinum. Grades: Highly Purified. CAS No. 61758-77-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C8H14N2O4Pt. US Biological Life Sciences. | Worldwide |
| 1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt | 1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt is used to prepare polyethyleneglycol-modified liposomal doxorubicin for therapies against drug resistant tumors. It is also used in the PEGylated liposomal drug formulation of the anti-cancer agent oxaliplatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 200880-42-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C42H82NaO10P. US Biological Life Sciences. | Worldwide |
| (1R, 2R) -1, 2-Cyclohexane diaminedinitrate Platinum | (1R, 2R) -1, 2-Cyclohexane diaminedinitrate Platinum is an intermediate in the synthesis of Oxaliplatin (O845075) related compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C6H14N4O6Pt. US Biological Life Sciences. | Worldwide |
| ART26.12 | ART26.12 is an orally active FABP5 inhibitor with anti-cannabinoid properties. ART26.12 effectively prevents and alleviates Oxaliplatin (HY-17371)-induced pain through lipid modulation and cannabinoid receptor activation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2766800-24-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159115. | |
| AZ 10397767 | AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM). It significantly reduced the numbers of infiltrating neutrophils into both in vitro and in vivo tumor models and slows growing tumors. It attenuates oxaliplatin-induced NF-κB activation and increases oxaliplatin cytotoxicity, thus potentiates oxaliplatin-induced apoptosis in AIPC cells. It may be potential for treating cystic fibrosis and chronic obstructive pulmonary disease. It is orally bioavailable. Synonyms: AZ-10397767; AZ 10397767; AZ10397767. 5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one. Grades: ≥98% by HPLC. CAS No. 333742-63-5. Molecular formula: C15H14ClFN4O2S2. Mole weight: 400.88. | |
| Diaquo [ (1R, 2R) -1, 2-cyclohexanediamine] platinum Dinitrate | Oxaliplatin intermediate as anti-cancer therapeutic agent and dual therapeutic/imaging contrast agent. Group: Biochemicals. Alternative Names: (SP-4-2)-. Grades: Highly Purified. CAS No. 94042-08-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Nystatin | Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion [1] [2]. Nystatin is a cholesterol-sequestering agent [3] , partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis [5]. Uses: Scientific research. Group: Natural products. CAS No. 1400-61-9. Pack Sizes: 500 mg. Product ID: HY-17409. | |
| Nystatin | Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion. Nystatin is a cholesterol-sequestering agent, partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis. Group: Inhibitors. Alternative Names: MORONAL; MYCOSTATIN; MYCOSTATIN(R); NYSTATIN, STREPTOMYCES NOURSEI; NYSFUNGIN; NYSTATIN; biofanal; candio-hermal. CAS No. 1400-61-9. Molecular formula: C47H75NO17. Mole weight: 926.09. Appearance: suspension. Purity: 0.9829. Canonical SMILES: C[C@@H]1OC (C[C@H] (O)C[C@H] (O)C[C@H] (O)CC[C@@H] (O)[C@H] (O)C[C@@] (O) (O[C@H]2C[C@H] (/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@@H] ([C@@H] (O)[C@H]1C)C)O[C@H]3[C@@H] (O)[C@@H] (N)[C@H] (O)[C@@H] (C)O3)C[C@H] (O)[C@H]2C (O)=O)=O. [Nystatin A1]. Catalog: ACM1400619. | |
| Osemitamab | Osemitamab is an IgG1 antibody targeting to human claudin-18.2. Osemitamab consists of human-Mus musculus monoclonal TST001 γ1-chain, disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer (ACI). Osemitamab in combination with Capecitabine (HY-B0016) and Oxaliplatin (HY-17371), can be used for G/GEJ cancer study [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TST001. CAS No. 2460539-61-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9991. | |
| Oxalic Acid | An impurity of oxaliplatin which is a coordination complex that is used in cancer chemotherapy. A reducing agent and its conjugate base, known as oxalate (C2O42?), is a useful chelating agent for metal cations. Group: Biochemicals. Alternative Names: Ethanedioic Acid; Aktisal; Aquisal; DeerClean; NSC 132055; NSC 151956; NSC 62774; NSC 76990; Ultraplast Activate S 52. Grades: Highly Purified. CAS No. 144-62-7. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| Oxalic Acid-(1,2-13C2) | Oxalic Acid-(1,2-13C2) is the labelled analog of Oxalic Acid (O845120) which is an impurity of oxaliplatin which is a coordination complex that is used in cancer chemotherapy. It is also a reducing agent and its conjugate base, known as oxalate (C2O42?), is a useful chelating agent for metal cations. Group: Biochemicals. Grades: Highly Purified. CAS No. 62654-02-8. Pack Sizes: 5mg, 10mg. Molecular Formula: 13C2H2O4. US Biological Life Sciences. | Worldwide |
| S1RA | S1RA (E-52862) is a highly selective σ1 receptor (σ1R) antagonist with K i s of 17 nM and 23.5 nM for human σ1R and guinea pig σ1R, respectively. S1RA has Moderate antagonistic activity for human 5-HT 2B receptor (K i = 328 nM). S1RA has antinociceptive effects in neuropathic pain models. S1RA prevents mechanical and cold hypersensitivity in Oxaliplatin (HY-17371)-treated mice [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-52862. CAS No. 878141-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-18099. | |
| Satraplatin | Satraplatin, also known as JM216, is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. It has not yet received approval from the U.S. Food and Drug Administration. First mentioned in the medical literature in 1993, satraplatin is the first orally active platinum-based chemotherapeutic drug; other available platinum analogues-cisplatin, carboplatin, and oxaliplatin-must be given intravenously. It is made available in the United States jointly by Spectrum Pharmaceuticals and GPC Biotech under the name SPERA (Satraplatin Expanded Rapid Access). The drug has also been used in the treatment of lung and ovarian cancers. The proposed mode of action is that the compound binds to the DNA of cancer cells rendering them incapable of dividing. Synonyms: BMS-182751; BMS 182751; BMS182751; JM 216; JM216; JM-216. CAS No. 129580-63-8. Molecular formula: C10H24Cl2N2O4Pt. Mole weight: 500.28. | |
| SBHA (Suberohydroxamic acid, Suberic bis-hydroxamic acid, N, N'-dihydroxyoctane diamide) | SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50=0.25uM) and HDAC3 (IC50=0.30uM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 38937-66-5. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. | Worldwide |
| trans-L-Diaminocyclohexane oxalatoplatinum | trans-L-Diaminocyclohexane oxalatoplatinum. Group: Biochemicals. Alternative Names: [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioata(2-)-O,O']platinum; Oxaliplatin. Grades: Highly Purified. CAS No. 61825-94-3. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C8H14N2O4Pt. US Biological Life Sciences. | Worldwide |
| TREM2-IN-1 | TREM2-IN-1 (OPA) is a TREM2 inhibitor derived from oxaliplatin and artesunate. TREM2-IN-1 can relieves immunosuppressive tumor microenvironment and enhancing chemical anticancer efficiency. TREM2-IN-1 deters the tumor growth in mice models bearing MC38 colorectal tumor by reducing the number of CD206 + and CX 3 CR1 + immunosuppressive macrophages. TREM2-IN-1 also promotes the expansion and infiltration of immunostimulatory dendritic, cytotoxic T and natural killer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2000236-36-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160421. | |
| Veliparib | Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. In HCT-116 and HT-29 cell lines, the ability of ABT-888 to synergize the effect of the anti-cancer agents, SN38 or oxaliplatin, was determined using the SRB assay. PARP activity was significantly reduced in samples treated with SN38 in combination with ABT-888 (>4 fold at 24 h). Uses: For research used only. Synonyms: (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide; ABT888; ABT-888; ABT 888; Veliparib. Grades: 0.99. CAS No. 912444-00-9. Molecular formula: C13H16N4O. Mole weight: 244.298. | |
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